• 분석과학
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• 제34권2호
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• pp.87-98
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• 2021

In this study, we developed the nanoparticle multi-generator by 3D printer fusion deposition modeling (FDM) method that can reliably generate and deliver nanoparticles at a constant concentration for inhalation risk assessment. A white ABS filament was used as the test material, and SMPS was used for concentration analysis such as particle size and particle distribution. In the case of particle size, the particle size was divided by 100 nm or less and 100 to 1,000 nm, and the number of particles concentration, mass concentration, median diameter of particles, geometric average particle diameter, etc were measured. The occurrence conditions were the extruder temperature, the extruding speed of the nozzle, and the air flow rate, and experiments were conducted according to the change of conditions including the manufacturer's standard conditions. In addition, the utility of inhalation risk assessment was reviewed through a stability maintenance experiment for 6 h. As a result of the experiment, the size of the nanoparticles increased as the discharger temperature increased, as the discharge speed of the nozzle increased, and as the air flow rate decreased. Also, a constant pattern was shown according to the conditions. Even when particles were generated for a long time (6 h), the concentration was kept constant without significant deviation. The distribution of the particles was approximately 80 % for particles of 60 nm to 260 nm, 1.7 % for 1 ㎛ or larger, 0.908 mg/㎥ for the mass concentration, 111 nm for MMAD and 2.10 for GSD. Most of the ABS particles were circular with a size of less than 10 nm, and these circular particles were aggregated to form a cluster of grape with a size of several tens to several hundred nm.

• 한국자기공명학회논문지
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• 제24권4호
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• pp.136-142
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• 2020

Apolipoprotein B-100 (apo B-100), the main protein component that makes up LDL (Low density lipoprotein), consists of 4,536 amino acids and serves to combine with the LDL receptor. The oxidized LDL peptides by malondialdehyde (MDA) or acetylation in vivo were act as immunoglobulin (Ig) antigens and peptide groups were classified into 7 peptide groups with subsequent 20 amino acids (P1-P302). The biomimetic peptide P99 (KGTYG LSCQR DPNTG RLNGE) out of B-group peptides carrying the highest value of IgM antigens were selected for structural studies that may provide antigen specificity. Circular Dichroism (CD) spectra were measured for peptide secondary structure in the range of 190-260 nm. Experimental results show that P99 has pseudo α-helice and random coil structure. Homonuclear (COSY, TOCSY, NOESY) 2D-NMR experiments were carried out for NMR signal assignments and structure determination for P99. On the basis of these completely assigned NMR spectra and proton distance information, distance geometry (DG) and molecular dynamic (MD) were carried out to determine the structures of P99. The proposed structure was selected by comparisons between experimental NOE spectra and back-calculated 2D NOE results from determined structure showing acceptable agreement. The total Root-Mean-Square-Deviation (RMSD) value of P99 obtained upon superposition of all atoms were in the set range. The solution state P99 has mixed structure of pseudo α-helix and β-turn(Gln[9] to Thr[13]). These NMR results are well consistent with secondary structure from experimental results of circular dichroism. Structural studies based on NMR may contribute to the prevent oxidation studies of atherosclerosis and observed conformational characteristics of apo B-100 in LDL using monoclonal antibodies.

• 대한토목학회논문집
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• 제29권5A호
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• pp.421-431
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• 2009

본 연구는 유도초음파를 기반으로 한 구조물 건전성 모니터링 알고리즘 검증에 관한 것이다. 유도초음파 중 램파를 기반으로 하는 능동검사시스템을 사용하였으며 본 알고리즘의 적용에 관한 기초연구로서 강판에 표면결함인 원형노치를 감지하는 실험을 수행하였다. Pitch-catch방법으로 강판 표면 원형노치에 대한 손상 탐상을 수행하여 손상전후의 $S_0$모드를 비교함으로써 손상 특성을 파악하며 손상전후 신호의 수학적 차에 의해 구한 산란램파(scatter)에 의해 손상을 평가할 수 있다. 손상전후 신호의 $S_0$모드 램파를 분석하기 위해서 연속 가보 웨이블릿 변환을 사용하여 전파시간을 구할 수 있다. 본 알고리즘은 손상모니터링 다각형과 Pitch-catch 방법을 기초로 하며 손상 위치표정값들의 평균과 표준편차에 의해 손상위치표정 및 크기를 정확히 추정 가능함이 검증되었다.

• 터널과지하공간
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• 제13권5호
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• pp.397-402
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• 2003

일반적으로 암반의 물성은 암반이 가지고 있는 불확실성이란 특성 때문에 하나의 대표치로 표현되는 것보다는 어느 정도의 분산성을 포함하는 값으로 표현되는 것이 타당하다. 이러한 특성은 지하구조물 설계에 중요한 부분이지만 아직까지 잘 정립되지 못한 부분이다. 확률유한요소법은 결정론적 유한요소법에 대비되는 말로써 구조계의 불확실성을 해석에 반영하기 위해 개발된 방법이다. 따라서, 이 방법을 이용하면 구조계의 응답 변화도를 얻을 수 있고 이를 통하여 확률적 안정성 분석이 이루어 질 수 있다. 본 연구에서는 암반물성(변형계수)을 평균과 표준편차로 정의되는 확률변수로 표현하여 정수압상태의 암반에 원형공동이 굴착될 경우 변위의 응답변화도를 분석하였다. 분석된 변위의 응답변화도는 변형계수의 표준편차에 따라 상당한 편차를 보이고 있어 신뢰성 있는 변형계수의 평균과 표준편차를 이용한 지하구조물의 확률적 안정성 분석이 이루어져야 할 필요성을 보여주고 있다.

• 한국실내디자인학회논문집
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• 제15권6호
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• pp.77-88
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• 2006

According to critics and architects, non-linear structure is not only an organic form of space, but also a form of space detached from modem style. Accordingly, non-linear structure can be accepted as an alternative to what has remained unsolved by deconstructionist. However, they are criticized for not clarifying the interdependent relationship between non-linearity of space and cognitive structure of human being. They ended up remaining the hypothesis just an intuitive and abstract one. This research began on the basis that their hypothesis is hard to be objectified, and it needs further inquiry. The purpose of this thesis is to explore how the redundant factors constitute non-linear structures of digital media centered space design. Geometric compositions of space structure were analyzed to define what types of redundant factors are contrived in the process of visual information. This study about the visual form, researching the Information Theory, and then offer a quantitative analysis that makes those more objective. Space structure and geometric composition were analyzed to define what types of redundancy are contrived in the process of visual information. In particular, I put higher theoretical emphasis on what characteristics are ensued in the process of structuring spaces than any other subjects. Followings are the conclusion of analysis. First, as a result of examining, we can assume that NOX' space structure is not a chaotic form, but has an operating the form of its own. Second, in case of curvilinear, the structure was found redundancy on mid deviation ratio and discontinuous circular fabric. Although most of their structures appeared complex with a higher coherent constant, they were found to be stable factors because of the low deviation ratio between systems. The amount of surplus information was stable structure as well.

• 대한기계학회논문집A
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• 제21권7호
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• pp.1166-1173
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• 1997

Due to progress in manufacturing techniques, the performance of the harmonic drive has been improved but not sufficiently. One of the important problems which the current harmonic drive has is that while there is the potential for having a wider tooth contact area, the total number of teeth engaged simultaneously is still small. This is mainly due to the involute tooth profile. Hence, in this study, the cycloid-type tooth profile is developed to improve this problem. This paper represents the design methodology and performance evaluation f the cycloid-type harmonic drive. Cycloide tooth profile was derived by analyzing geometry of the tooth engagement and the contact mechanisms of the tooth which were examined and analyzed by load analysis. The stress due to elastic deformation of a flexspline was also obtained by approximate formula and computer analysis. Finally, the cycloid-type harmonic drive with 1:100 speed ratio was manufactured and the performance of the harmonic drive was evaluated.

• 대한기계학회논문집
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• 제15권1호
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• pp.154-162
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• 1991

본 연구에서는 내치차의 절삭가공에서 발생하는 치형오차를 대상으로 이에 영 향을 미치는 제반 조건 중, 커터의 이론적인 인벌류트 치형으로부터의 편차, 커터와 내치차의 잇수에 의한 간섭, 창성과정(generating process)중 원주방향 이송과 같은 가공조건이 기어의 치형오차에 미치는 영향을 분석하고 이를 최소로 하는 조건을 유도 하여 양질의 내치차 생산에 기여 하고자 한다.

• 수산해양기술연구
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• 제48권3호
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• pp.235-241
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• 2012

The efficiency tests of automatic positioning transmitter (APT) using satellite on life jacket were carried out to minimize casualties of fishermen and to make system optimization for effective SAR (Search and Rescue) operation. As the result of the tests, average position was equaled on the comparison between SPOT using low earth orbit satellite and DGPS (Differential Global Positining System), but standard deviation of DGPS for latitude and longitude were 66.4% and 46.3% smaller than those of SPOT. The position precision of SPOT was almost two times lower than LGT using geostationary satellite to compare 95% circular error probability. However, the success rate of receiver for SPOT was revealed as 86.5~94.1% on the experiments in the South Sea and the West Sea and it was 4.5 times higher than LGT. Therefore, SPOT is expected to contribute greatly to the rapid rescue of victim.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2009년도 하계학술발표대회 논문집
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• pp.804-809
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• 2009

The present study measured frost pattern on a cylinder to propose empirical correlation equations for the local and average frost thickness, frost density and frost mass. The key parameters were diameter of the cylinders (7mm, 20mm), cooling surface temperature of the circular tube, absolute humidity of air, air temperature and air velocity. A 50% ethylene glycol aqueous solution was applied as a coolant. The frost thicknesses at both front and rear were larger than those at the other parts, while they were increased as diameter of the cylinder was increased. The local frost thicknesses at high air velocity were more uniform than those at low air velocity. The values predicted by Kim et al. under the freezer condition showed larger by the maximum of $30{\sim}50%$ than the measured data under heat pump condition. The empirical correlations for the local and average frost thickness and frost mass were proposed. The correlation equations for the frost thickness and frost mass under the heat pump condition in the present study might predict more accurate than the other correlation equations. The proposed correlations might be applied for the freezer condition within the maximum 15% deviation from the previous correlations under freezer condition.

• Advances in materials Research
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• 제6권2호
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• pp.155-168
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• 2017

The terrorist attacks and dangers by bomb blast have turned into an emerging issue throughout the world and the protection of the people and structures against terrorist acts depends on the prediction of the response of structures under blast and shock load. In this paper, behavior of aluminum and unidirectionally reinforced E-Glass Epoxy composite plates with and without focal circular holes subjected to shock loading has been identified. For isotropic and orthotropic plates (with and without holes) the classical normal mode approach has been utilized as a part of the processing of theoretical results. To obtain the accurate results, convergence of the results was considered and a number of modes were selected for plate with and without hole individually. Using a shock tube as a loading device, tests have been conducted to composite plates to verify the theoretical results. Moreover, peak dynamic strains, investigated by experiments are also compared with the theoretical values and deviation of the results are discussed accordingly. The strain-time histories are likewise indicated for a specific gauge area for aluminum and composite plates. Comparison of dynamic-amplification factors between the isotropic and the orthotropic plates with and without hole has been discussed.