• 품질경영학회지
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• 제46권4호
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• pp.863-876
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• 2018

Purpose: There are several KPI(key performance indicators) models: BSC(balanced scorecard), IPOO(Input-process-output-outcomes) indicators, QCDP(quality-cost-delivery-productivity) indicators. This paper analyze these models and gives some suggestions to help the effective usage of KPI. Methods: This paper reviews and summarize the criteria to evaluate the PI(performance indicators) through literature review. Evaluation and analysis on the PI factors of the KPI developing models is performed by the criteria. Results: Criteria to evaluate the PI, which can be used to evaluate the goodness of PI is suggested. This paper also proposes some suggestions for the KPI models and their factors for the effective development of PI in the organization. Conclusion: This research will help the managers to develop and select useful PI and KPI for their business and processes.

• Archives of Pharmacal Research
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• 제25권6호
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• pp.978-983
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• 2002

Small intestinal transit (SIT) has often been regarded as an index of pathophysiological state of postoperative ileus (PI) in rats. The reliability of SIT as an index of PI was examined in the present study. PI was induced via abdominal surgery (i.e., laparotomy with evisceration and manipulation) in rats. For one group of PI-induced rats, SIT of a charcoal test meal was measured. When necessary, the physical state (i.e., severity and site of distension) of the gastrointestinal (GI) tract in each rat was visually examined. For another group of PI-induced rats, abdominal X-ray radiographs were obtained after introducing the barium sulfate suspension. The abdomen was then opened and the physical state of the GI tract was visually examined. The SIT was decreased in most of the PI-induced rats, and the GI distension was observed, with substantial intersubject variations, in all of the PI-induced rats. However, no linear relationship was evident between the SIT and the severity of GI distension (e.g., at 20 h after PI induction). Instead, the severity and site of GI distension could be monitored by the X-ray radiology. Therefore, the use of SIT as an index of PI should be substantially limited.

• 조명전기설비학회논문지
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• 제28권2호
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• pp.9-18
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• 2014

This paper proposes the fuzzy PI controller for maximum power point tracking(MPPT) control of photovoltaic system. The output characteristics of the solar cell are a nonlinear and affected by a temperature, the solar radiation. The MPPT control is a very important technique in order to increase an output and efficiency of the photovoltaic system. The conventional perturbation and observation(PO) and incremental conductance(IC) are the method which finding maximum power point(MPP) by the continued self-excitation vibration, and uses the fixed step size. If the fixed step size is a large, the tracking speed of maximum power point is faster, but the tracking accuracy in the steady state is decreased. On the contrary, when the fixed step size is a small, the tracking accuracy is increased and the tracking speed is slower. Therefore, this paper proposes the MPPT control using the fuzzy PI controller that can be improve a MPPT control performance. The fuzzy PI controller is adjusted a input of PI controller by fuzzy control and compensated a cumulative error of fuzzy control by PI controller. The fuzzy PI MPPT control is compared to conventional PO and IC MPPT method for various temperature and radiation condition. This paper proves the validity of the fuzzy PI controller using these results.

• The Korean Journal of Physiology and Pharmacology
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• 제16권5호
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• pp.361-365
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• 2012

Anti-tumor activity of the proteins from Gecko (GP) on cervical cancer cells, and its signaling mechanisms were assessed by viable cell counting, propidium iodide (PI) staining, and Western blot analysis. GP induced the cell death of HeLa cells in a dose-dependent manner while it did not affect the viability of normal cells. Western blot analysis showed that GP decreased the activation of Akt, and co-administration of GP and Akt inhibitors synergistically exerted anti-tumor activities on HeLa cells, suggesting the involvement of PI3-kinase/Akt pathway in GP-induced cell death of the cancer cells. Indeed, the cytotoxic effect of GP against HeLa cells was inhibited by overexpression of constituvely active form of Akt in HeLa cells. The candidates of the functional proteins in GP were analyzed by Mass-spectrum. Taken together, our results suggest that GP elicits anti-tumor activity against HeLa cells by inhibition of PI3-kinase/Akt pathway.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.156-156
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• 2001

We have previously shown that H-ras, but N-ras, induces an invasiveness and cell motility in human breast epithelial cells (MCFl0A), while both H-ras and N-ras induce transformed phenotype. It has been recently shown that phosphatidylinositol 3-kinase (PI3K) plays an important role on cell migration. In the present study, we wished to investigate the functional role of PI3K in H-ras-induced invasive phenotype in MCF10A cells.(omitted)

• 한국독성학회:학술대회논문집
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• 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
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• pp.142-142
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• 2002

Many studies have identified the phosphatidylinositol 3-kinase (PI3K) as a key regulator for various cellular functions including cell survival, growth and motility. We have previously shown that H-ras, but not N-ras, induces invasiveness and motility in human breast epithelial cells (MCF10A), while both H-ras and N-ras induce transformed phenotype.(omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.223.1-223.1
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• 2003

Many studies have identified the phosphatidylinositol 3-kinase (PI3K) as a key regulator for various cellular functions including cell survival, growth and motility. We have previously shown that H-ras, but not N-ras. induces invasiveness and motility in human breast epithelial cells (MCF10A), while both H-ras and N-ras induce transformed phenotype. In the present study, we wished to investigate the functional role of PI3K pathway in H-ra-induced invasive phenotype and motility of MCF10A cells. (omitted)

• 분석과학
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• 제14권4호
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• pp.340-348
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• 2001

감귤류와 한국산 청피에 함유된 glycosided flavonoids (naringenin, naringin, narirutin, hesperidin, hesperetin)를 HPLC, UV, 그리고 NMR로 분리하고 분석하였다. Glycosided flavonoids의 함량을 감귤종류와 성숙도에 따라 비교하였다. 청피의 주성분을 hesperidin이었고, narirutin, hesperetin도 상당량 들어있었다. 지실의 주성분은 naringin, narirutin, naringenin이었고, 지각의 주성분은 narirutin, hesperidin이었다. 밀감과 오렌지의 주성분은 narirutin, hesperidin이었으며, glycosided flabonoids의 함량은 감귤의 성숙도에 따라 감소하였다.

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2003년도 추계학술대회
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• pp.144-144
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• 2003

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2002년도 Molecular and Cellular Response to Toxic Substances
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• pp.142-142
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• 2002