• Title/Summary/Keyword: Chung-Sup Yoon

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Effects of Fasting versus Non-Fasting on Emetic Complications in Radiological Examinations Using Intravascular Non-Ionic Iodinated Contrast Media: A Systematic Review and Meta-Analysis

  • Hyewon Choi;Hyunsook Hong;Min Jae Cha;Soon Ho Yoon
    • Korean Journal of Radiology
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    • v.24 no.10
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    • pp.996-1005
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    • 2023
  • Objective: To compare the incidence of aspiration pneumonia, nausea, and vomiting after intravascular administration of nonionic iodinated contrast media (ICM) between patients who fasted before contrast injection and those who did not. Materials and Methods: Ovid-MEDLINE and Embase databases were searched from their inception dates until September 2022 to identify original articles that met the following criteria: 1) randomized controlled trials or observational studies, 2) separate reports of the incidence of aspiration pneumonia, nausea, and vomiting after intravascular injection of non-ionic ICM, and 3) inclusion of patients undergoing radiological examinations without fasting. A bivariate beta-binomial model was used to compare the risk difference in adverse events between fasting and non-fasting groups. The I2 statistic was used to assess heterogeneity across the studies. Results: Ten studies, encompassing 308013 patients (non-fasting, 158442), were included in this meta-analysis. No cases of aspiration pneumonia were reported. The pooled incidence of nausea was 4.6% (95% confidence interval [CI]: 1.4%, 7.8%) in the fasting group and 4.6% (95% CI: 1.1%, 8.1%) in the non-fasting group. The pooled incidence of vomiting was 2.1% (95% CI: 0.0%, 4.2%) in the fasting group and 2.5% (95% CI: 0.7%, 4.2%) in the non-fasting group. The risk difference (incidence in the non-fasting group-incidence in the fasting group) in the incidence of nausea and vomiting was 0.0% (95% CI: -4.7%, 4.7%) and 0.4% (95% CI: -2.3%, 3.1%), respectively. Heterogeneity between the studies was low (I2 = 0%-13.5%). Conclusion: Lack of fasting before intravascular administration of non-ionic ICM for radiological examinations did not increase the risk of emetic complications significantly. This finding suggests that hospitals can relax fasting policies without compromising patient safety.

Quantitative Analysis of (+)-Catechin and Diosgenin from Smilax china L. Rhizome (토복령에 함유되는 (+)-Catechin과 Diosgenin의 함량분석)

  • Yin, Jun;Yoon, Ki Hoon;Hwang, Yoon Jeong;Lee, Ji Yeon;Shin, Hwa Sup;Lee, Min Won
    • Korean Journal of Pharmacognosy
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    • v.46 no.3
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    • pp.189-194
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    • 2015
  • Validation and contents determination of (+)-catechin and diosgenin from Smilax china L. rhizome (SC) were confirmed using Ultra-Performance Liquid Chromatography (UPLC). (+)-Catechin was isolated from 60% prethanol SC extract and diosgenin was isolated by acid hydrolysis of saponin fraction from 60% prethanol extract of SC. Finally we have established the validation of the isolated compounds [(+)-catechin, diosgenin] and contents determinations of (+)-catechin and diosgenin by UPLC on 60% prethanol extract of SC [(+)-catechin: 0.06878%, diosgenin: 0.48169%], and on hot water extract of SC [(+)-catechin: 0.06584%, diosgenin: 0.42178%].

Occupational Exposure during Intraperitoneal Pressurized Aerosol Chemotherapy Using Doxorubicin in a Pig Model

  • Wongeon Jung;Mijin Park;Soo Jin Park;Eun Ji Lee;Hee Seung Kim;Sun Ho Chung;Chungsik Yoon
    • Safety and Health at Work
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    • v.14 no.2
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    • pp.237-242
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    • 2023
  • Background: This study evaluated occupational exposure levels of doxorubicin in healthcare workers performing rotational intraperitoneal pressurized aerosol chemotherapy (PIPAC) procedures. Methods: All samples were collected during PIPAC procedures applying doxorubicin to an experimental animal model (pigs). All procedures were applied to seven pigs, each for approximately 44 min. Surface samples (n = 51) were obtained from substances contaminating the PIPAC devices, surrounding objects, and protective equipment. Airborne samples were also collected around the operating table (n = 39). All samples were analyzed using ultra-high performance liquid chromatography-mass spectrometry. Results: Among the surface samples, doxorubicin was detected in only five samples (9.8%) that were directly exposed to antineoplastic drug aerosols in the abdominal cavity originating from PIPAC devices. The telescopes showed concentrations of 0.48-5.44 ng/cm2 and the trocar showed 0.98 ng/cm2 in the region where the spraying nozzles were inserted. The syringe line connector showed a maximum concentration of 181.07 ng/cm2, following a leakage. Contamination was not detected on the surgeons' gloves or shoes. Objects surrounding the operating table, including tables, operating lights, entrance doors, and trocar holders, were found to be uncontaminated. All air samples collected at locations where healthcare workers performed procedures were found to be uncontaminated. Conclusions: Most air and surface samples were uncontaminated or showed very low doxorubicin concentrations during PIPAC procedures. However, there remains a potential for leakage, in which case dermal exposure may occur. Safety protocols related to leakage accidents, selection of appropriate protective equipment, and the use of disposable devices are necessary to prevent occupational exposure.

Two Layered Image Tile Mosaics (두 층 이미지 타일 모자이크)

  • Kang, Dong-Wann;Park, Young-Sup;Seo, Sang-Hyun;Yoon, Kyung-Hyun
    • Journal of the Korea Computer Graphics Society
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    • v.12 no.2
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    • pp.9-11
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    • 2006
  • 본 논문은 원 영상의 세부 묘사를 유지하는 사진 타일 모자이크 방법을 제안한다. 이 방법은 타일 내부의 세부 묘사를 위한 사진 타일의 사용과 타일간의 빈 공간을 제거하기 위한 겹쳐진 타일의 사용을 통해 구현된다. 본 논문에서 제시한 방법은 다음 세 단계로 구성된다. 첫째, 에지 회피 기법이 적용된 CVD를 통해 메인 타일의 위치를 얻고, 딜로니 삼각형화를 이용해 서브 타일의 위치를 계산한다. 둘째, 타일간의 관계를 고려해 타일의 크기와 방향성을 구한다. 셋째, 사진 타일을 사용하기 위해 포토 모자이크 기법을 사용한다. 이때, 다단계 인덱싱기법을 통해 사진 검색의 속도를 높인다. 위의 과정을 통해 타일 간의 빈공간이 최소화되고 타일 내부의 세부 묘사가 극대화된 모자이크 영상을 얻는다.

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Image Mosaic based on generation of color paper (색종이 타일 생성을 기반으로 한 이미지 모자이크)

  • Gi, Yong-Jea;Park, Young-Sup;Seo, Sang-Hyun;Yoon, Kyung-Hyun
    • Journal of the Korea Computer Graphics Society
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    • v.11 no.3
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    • pp.28-33
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    • 2005
  • 본 논문은 색종이 리스트를 미리 생성하여 필요할 때마다 불러들여 찢어 붙이는 방법의 색종이 모자이크 렌더링 기법을 소개한다. 색종이 리스트는 색종이 이외에도 잡지와 같은 다양한 종이들을 미리 생성하여 사용할 수 있기 때문에 여러 가지 형태의 모자이크를 표현 할 수 있다는 장점을 가진다. 색종이 모자이크를 생성하기 위해서는 색종이 타일의 선택, 모양 결정, 그리고 배치의 3가지 과정을 거쳐야 한다. 먼저 색종이 타일을 붙일 위치에서 가장 알맞은 타일을 리스트로부터 선택하고, 적절한 모양으로 찢는다. 마지막으로 입력 영상의 특징(경계선 등)이 유지될 수 있도록 타일을 배치하여 최종 결과 영상을 생성한다.

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