• 제목/요약/키워드: Chronic depression

검색결과 619건 처리시간 0.029초

자유로운 신체운동과 멜라토닌이 우울장애 동물모델에 미치는 효과 (Effects of Physical Activity and Melatonin in a Rat Model of Depression Induced by Chronic Stress)

  • 성호현;정성모;김시원;김연정
    • Journal of Korean Biological Nursing Science
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    • 제17권1호
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    • pp.37-43
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    • 2015
  • Purpose: Stress, depending on its intensity and duration, results in either adaptive or maladaptive physiological and psychological changes in humans. Also, it was found that stressful experiences increase the signs of behavioral despair in rodents. On the other hand, exercise and melatonin treatment is believed to have many beneficial effects on health. Thus, this study was designed to evaluate the anti-depressant effects of physical activity and melatonin against chronic stress-induced depression in rats. Methods: Adult male Sprague-Dawley(SD) rats(200-250g, 7 weeks of age) were subjected to depression induced by chronic stress. Chronic depression was induced with forced-swim stress (FSS) and repeated change of light-dark cycle for 4 weeks. In the last 2 weeks, some rats were confined in a cage enriched with a running wheel, seesaw and chewed a ball from 19:00 to 07:00 every day. Melatonin was injected intra-peritoneally (I.P), and the rats received intraperitoneal injections of melatonin (15 mg/kg). The Forced Swim Test (FST) was performed to evaluate the immobility behaviors of rats for a 5 min test. Results: It was found that, the immobility time in FST was significantly (p<.05) lower in physical exercise ($M=58.83{\pm}22.73$) and melatonin ($M=67.33{\pm}37.73$) than in depressive rats ($M=145.93{\pm}63.16$) without physical activity. Also, TPH positive cell in dorsal raphe was significantly (p<.05) higher in exercise ($M=457.38{\pm}103.21$) and melatonin ($M=425.38{\pm}111.56$) than in depressive rats ($M=258.25{\pm}89.13$). Conclusion: This study suggests that physical activity and melatonin produces antidepressant-like effect on stress-induced depression in rats. So, physical exercise and melatonin may be a good intervention in depression patients.

만성 요통환자의 수지요법 적용에 대한 효과 (The Effects of Koryo Hand-Acupuncture on the Patients with Chronic Low Back Pain)

  • 임난영;이여진
    • 대한간호학회지
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    • 제33권1호
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    • pp.79-86
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    • 2003
  • Purpose: The purpose of this study was to identify the effects of Koryo Hand-Acupuncture on health status(pain, trunk flexion, IADL, depression) of patients with chronic low back pain. Method: This study used a quasi experimental pre-test and post-test design. Data were collected from December 1st, 2000 to December 20th, 2001. 63 chronic low back pain patients(35 experimental group, 28 control group) admitted to the Back-School and consented to this study. The experimental group participated in treatment: Koryo Hand-Acupuncture and AB-Bong. Two groups was homogeneity. After 4 weeks the effects of treatment on the health status was measured between experimental and control group. Data were analyzed using SPSSWIN 10.0 with crosstab, t-test, and paired t-test. Result: In the experimental group, pain(t=4.85, p=.000) and IADL difficulty(t=2.05, p=.045) was significantly lower than those in the control group. It makes no difference trunk flexion(t=-1.60, p=.114) and depression(t=1.50, p=.138) between experimental and control group. Conclusion: These findings indicate that Koryo-Hand Acupuncture is an effective method for reducing pain and IADL difficulty in patients with chronic low back pain, and is considered as a independent nursing intervention for chronic low back pain.

일 대도시 여성노인의 우울에 영향을 미치는 요인 (Factors Influencing Depression of Elderly Women in a Metropolitan City)

  • 양승애
    • 한국보건간호학회지
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    • 제26권1호
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    • pp.158-173
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    • 2012
  • Purpose: This study was conducted in order to investigate factors related to depression of elderly women in a Metropolitan city. Methods: Subjects included 118 elderly women older than 65 years of age. Structured questionnaires were used for data collection, and descriptive statistics, t-test, ANOVA, Pearson correlation coefficients, and hierarchical regression analysis were performed for data analysis. Results: A significant difference in depression was observed according to number of chronic diseases(F=4.963, p=.001). Significant factors influencing depression included number of chronic diseases (${\beta}$=.265, p<.01), cognitive function (${\beta}$=.290, p<.01), quality of sleep(${\beta}$=.212, p<.01), and nutritional state (${\beta}$=.161, p<.05). These factors explained 54.2% of the variance. Conclusion: Findings of this study suggest the need for development of nursing strategies to decrease the incidence of depression in elderly women.

COVID-19로 인한 만성질환 관리 비대면 프로그램의 효과성 연구 (A Study on Effectiveness of Chronic Disease Online Program Due to COVID-19)

  • 김연미;김현진
    • 디지털융복합연구
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    • 제20권4호
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    • pp.759-768
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    • 2022
  • 본 연구의 목적은 코로나 19 장기화로 지역사회주민 만성질환 예방 관리를 위해 온라인 기반 만성질환관리 비대면 프로그램을 적용하여 그 효과를 확인하기 위한 단일군 전후 설계 유사실험 연구이다. 본 연구의 프로그램은 간호, 영양, 운동 프로그램으로 12주간 실시하였다. 대상자는 보건소 만성질환 관리센터를 이용하는 성인 남녀 69명으로 2021년 5월 3일부터 8월 6일까지 프로그램 적용 전후 수축기압, 이완기압, 공복 혈당, BMI와 우울, 삶의 질의 설문 도구를 사용하여 조사하였다. 자료 분석은 SPSS 20.0을 이용하여 분석하였다. 연구 결과, 수축기압, 이완기압, 공복혈당이 유의하게 감소하였으며, 삶의 질에서도 유의하게 나타났다. 우울은 유의하지 않았으나 경중 우울이 감소하였다. 따라서 위드 코로나 시대에 지속적인 만성 질환 관리를 위해 다양한 비대면 프로그램 프로그램을 개발하여 적용 관리한다면 심뇌혈관질환으로 이행을 방지하고 만성질환 예방 및 건강 유지 증진에 기여할 것이라 사료된다.

The Effect of Breathing Training on the Physical Function and Psychological Problems in Patients with Chronic Stroke

  • Lee, Dong-Kyu
    • The Journal of Korean Physical Therapy
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    • 제32권3호
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    • pp.146-151
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    • 2020
  • Purpose: To identify the effect of breathing training on the physical function and psychological problems in patients with chronic stroke. Methods: In total, 26 patients with chronic stroke were randomly assigned to one of two groups: the experimental group, who underwent breathing training and neurodevelopmental treatment, and the control group, who underwent neurodevelopmental treatment (13 patients per group). Physical function was evaluated using the balance and Activities of Daily Living (ADL). Psychological problems were assessed using the Depression. Balance was measured using the Berg Balance Scale (BBS). ADLs were measured using the Modified Barthel Index (MBI). Depression was measured using the Beck Depression Inventory (BDI). The BBS, MBI, and BDI were recorded before and after the 4-week treatment. Results: As a result of comparison within groups, the experimental and control group showed significant difference for BBS, MBI and BDI after the experiment (p<0.05). In comparison between two groups, the experimental group showed more significant difference in BBS, MBI and BDI than the control group (p<0.05). Conclusion: This study showed that breathing training was effective improvement physical function, and psychological problems in patients with chronic stroke.

우울증(憂鬱症)모델 흰쥐에 대한 조위승청탕(調胃升淸湯)과 fluoxetine의 항우울효과(抗憂鬱效果) 비교 (The effects of Jowiseungchungtang versus fluoxetine in the chronic mild stress model of depression in rats)

  • 류재면;김종우;지상은;김은주;박은혜;황의완
    • 동의신경정신과학회지
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    • 제15권1호
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    • pp.27-41
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    • 2004
  • This study was performed to evaluate the effects of Jowiseungchungtang and fluoxetine in the chronic mild stress(CMS) model of depression in rats. Chronic exposure to mild unpredictable stress was found to depress the consumption of sucrose solution in rats for 5 weeks. These CMS-treated rats were stratified into Jowiseungchungtang group, fluoxetine group and vehicle group. And control rats were also stratified into other CMS-treated group. The change of the consumption of sucrose solution was measured, and open field test were performed to investigate the anti-depression effect of Jowiseungchungtang and fluoxetine. The results were as follows : 1. The consumption of sucrose solution was significantly reversed in Jowiseungchungtang-treated group at 7 week, but there was no significant change in other groups. 2. CMS schedule decreased body weight. Jowiseungchungtang group and fluoxetine group showed significant decrease of body weight after 6 weeks. 3. In open field test, Jowiseungchungtang group and fluoxetine group showed no significant change of exploratory activity.

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Pain, Depression, Body Mass Index in Conscripts with Chronic Low Back Pain in South Korea

  • Lee, Ju Hwan;Um, Ki Mai;Wang, Jung San;Lee, Sa Gyeom;Park, Joo Hyun;Koo, Ja Pung;Kim, Jung Hee;Lee, Suk Hee;Moon, Ok Kon
    • 국제물리치료학회지
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    • 제5권1호
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    • pp.661-667
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    • 2014
  • This study is a cross-sectional study for conscripts with chronic low back pain, where it is designed to investigate general characteristics that conscripts with chronic low back pain carry, and it is also aimed to analyze the correlation as well as discrepancy within pain, depression and body mass index depending on their ranks. In this study, 90 Korean conscripts with chronic low back pain participated. And in order to analyze general characteristics as well as pain, depression and body mass index of the subjects, this study adopted a survey questionnaire upon general characteristics, and it also employed Visual Analogue Scacle(VAS) and Center for Epidemiological Studies Depression(CES-D) Scale which have proven their credibility, where BMI values for the subjects were calculated based on 'Asian Pacific standard' Body Mass Index(BMI). From the general characteristics exhibited by the subjects through this study, average age and average height of the subjects were $20.78{\pm}1.41$ and $175.97{\pm}5.34$ respectively; and corporals displayed the highest ratio of 42% with the chronic low back pain while 40% of the total subjects experienced the duration of the illness less than 6 to 9 months. Moreover, 57.8% of all subjects were reportedly suffering moderate pain, and 48% exhibited depression while 49% carried BMI value between 18.5 and $22.9kg/m^2$(normal range). Based on the analysis of correlation among pain, depression, discrepancy of BMI depending on the ranks and each independent variable, it appears that there is no significant difference amongst the ranks, and there is no correlation between independent variables; however, it was obvious that all groups divided by the ranks had a moderate pain(45-74mm), depression(${\geq}16$) and BMI value in normal range(18.5-22.9).

만성질환으로 입원한 노인 환자의 우울, 자아존중감 및 일상생활수행능력(ADL)간 관계연구 (The Relationship among Depression, Self-esteem and ADL in the Case of the Hospitalized Elderly Patients with Chronic Disease)

  • 여연옥;유은광
    • 성인간호학회지
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    • 제22권6호
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    • pp.676-686
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    • 2010
  • Purpose: This study has aimed to examine the relationship among self-esteem, Activities of Daily Living (ADL) and depression reported by hospitalized elderly patients with chronic diseases. Methods: A descriptive correlation study by means of a self-report questionnaire or face-to-face interview was used to collect data from 119 elderly patients who were hospitalized in a General Hospital from January 5 to February 25, 2010. Their levels of depression was measured using Short-Form Geriatric Depression Scale, self esteem using Jeon's, and activities of daily living using K-ADL. Results: 80.7% of the subjects experienced depression. Depression correlates with self-esteem (r=-.67) and ADL (r=.45). The influencing factors on depression were self-esteem, ADL, subjective health status, and family support satisfaction ($R^2=.57$), while self esteem in itself explained 45% of variance in depression. Conclusion: These findings indicate the importance of early detection of depression, which starts from the admission of patients and the continuing evaluation/management in daily life after discharge to ensure their well-being and quality of life. The development of program empowering self esteem, ADL and subjective health status with adequate family support during hospitalization and in daily life is indispensible.

만성 폐쇄성 폐질환 환자의 증상경험과 우울의 관계에 미치는 극복력의 매개효과 (The Mediating Effects of Resilience between Symptom Experience and Depression in Patients with Chronic Obstructive Pulmonary Disease)

  • 공경란;이은남
    • 성인간호학회지
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    • 제27권4호
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    • pp.375-383
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    • 2015
  • Purpose: The purpose of this study was to identify the relationship of resiliency and symptom experience and depression. Subjects (N=152) were patients with chronic obstructive pulmonary disease (COPD).admitted to D University Medical Center in B City. Methods: Data collection was conducted from July 20 to August 25, 2013. The levels of symptom, resilience, and depression were measured using a seven question symptom experience measuring instrument, a 25-question resilience instrument, and a 15-question Short Geriatric Depression Scale (SGDS). The collected data were analyzed by descriptive analysis, Pearson's correlation coefficients, and path analysis using SPSS/Win 19.0 and AMOS 5.0. Results: There was a significant negative correlation between symptom and resilience, a significant positive correlation between symptom and depression, and a significant negative correlation between resilience and depression. Symptom showed a direct effect on depression and an indirect effect on depression scores through resilience as a mediating variable. Conclusion: It is necessary to develop nursing intervention programs to relieve symptom in COPD patients, and to develop appropriate resilience enhancement programs to reduce their depression.

일 의료기관 이용자의 자살생각 영향요인 - 만성질환 노인을 중심으로 (Factors Affecting Suicidal Ideation by Medical Institutions Users - Focusing on elderly people with chronic diseases)

  • 임경태
    • 한국콘텐츠학회논문지
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    • 제19권6호
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    • pp.644-654
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    • 2019
  • 본 연구는 만성질환 노인들의 자살 생각에 대한 우울증, 자아 존중감 및 일상생활능력의 영향을 확인하기 위한 연구이다. 연구 대상자는 D 광역시에 소재한 종합병원의 외래 환자 및 입원 환자 170명이었다. 데이터 수집을 위한 설문 실시 후, t-test, ANOVA 및 다중 회귀분석을 실시하고 SPSS 12.0/win 프로그램을 사용하여 분석하였다. 결과에 따르면 자살 생각은 성별, 건강상태, 만성질환 진단명 및 자살시도의 경험에 영향을 받았으며, 우울증과 양의 상관관계가 있고 일상생활능력은 음의 상관관계로 나타났다. 자살시도 경험, 우울증, 자아 존중감, 일상생활능력은 자살생각에 50.8 %의 설명력을 보였다. 자살생각을 줄이기 위해서 우울증은 줄이고 일상생활능력을 향상시키는 중재 프로그램을 운영하여 만성질환 노인의 자살 생각을 줄여야 할 것이다.