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Epigenetic Regulation in the Brain after Spinal Cord Injury : A Comparative Study

  • Park, Bit-Na-Ri;Kim, Seok Won;Cho, Sung-Rae;Lee, Ji Yong;Lee, Young-Hee;Kim, Sung-Hoon
    • Journal of Korean Neurosurgical Society
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    • v.53 no.6
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    • pp.337-341
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    • 2013
  • Objective : After spinal cord injury (SCI), functional and structural reorganization occurs at multiple levels of brain including motor cortex. However, the underlying mechanism still remains unclear. The current study was performed to investigate the alterations in the expression of the main regulators of neuronal development, survival and death, in the brain following thoracic contusive SCI in a mouse model. Methods : Eight-week-old female imprinting control region mice (n=60; 30-35 g) were used in this study. We analyzed the expression levels of regulators such as brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF) and histone deacetylase (HDAC) 1 in the brain following thoracic contusive SCI. Results : The expression of BDNF levels were elevated significantly compared with control group at 2 weeks after injury (p<0.05). The expression of NGF levels were elevated at 2, 4 weeks compared with control group, but these difference were not significant (p>0.05). The GDNF levels were elevated at 2 week compared with control group, but these differences were not significant (p>0.05). The difference of HDAC1 levels were not significant at 2, 4 and 8 weeks compared with control group (p>0.05). Conclusion : These results demonstrate that the upregulation of BDNF may play on important role in brain reorganization after SCI.

Comparisons of Body Image, Depression, and Climacteric Symptoms among Middle-Aged Women with and without Thyroidectomy (갑상선절제술을 받은 중년여성과 받지 않은 중년여성의 신체상, 우울, 갱년기 증상 비교)

  • Yun, Byeong Sook;Back, Ji Eun;Lee, June Sang;Park, Mi Jeong;Lim, Young Mi
    • Journal of Korean Clinical Nursing Research
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    • v.14 no.3
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    • pp.5-14
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    • 2008
  • Purpose: The purpose of this study was to compare body image, depression, and climacteric symptoms among middle-aged women with and without thyroidectomy. Method: The research design was a comparative descriptive study using a self-report questionnaire. A total of 102 women aged 40~59 years were recruited using a convenient sampling method. A total of 52 women out of 102 were within a year after thyroidectomy due to benign disease. The rest of the subjects were healthy women without any previous diseases in thyroid. The instruments included Body Image Concern Inventory, Climacteric symptoms, and Center for Epidemiological Studies Depression Scale. The data were analyzed by descriptive statistics, t-test, $x^2$-test, one-way ANOVA, and correlation analysis. Results: There were no significantly differences in age, education, menstruation states between women with and without thyroidectomy. The demographic characteristics of two groups were homogeneous. There were significantly statistical differences in body image (t= 8.456, p=.000), and depression (t=3.142, p=.002) between the groups. There was, however, no significantly differences of climacteric symptoms. In addition, in women with thyroidectomy, no significant associations were found among body image, depression, and climacteric symptoms. Conclusion: The findings demonstrated the need to develop an effective nursing intervention to increase body image and to reduce depression in middle-aged women after thyroidectomy.

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The Humanities Course Experience of Multicultural Couples : Focusing on Movie Making (다문화부부의 인문학강좌 참여경험 : 영화만들기를 중심으로)

  • Kang, Jaime M.;Byun, Soung-Won;Kim, Deok-Soon;Kim, Jeong-Uk;Park, Hyun-Jung
    • Journal of Digital Convergence
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    • v.11 no.7
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    • pp.305-312
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    • 2013
  • The purpose of this qualitative study is to analyze the experience of multicultural couples who participated in the movie making educational activity within the program "Communication Development among Multicultural and Indigenous Couples Through Intercultural Praxis." This program was held for 8 months from March 10, 2012 to November 11, 2012. Among the participants, 4 couples agreed for both individual and group interviews and provided data for this paper. The interview result can be categorized into the following four: quality relationship, acceptance and support, positive thinking, and accomplishment.

A CLINICAL STUDY ON THE CARE OF ODONTOGENIC INFECTIONS IN THE ADMISSION PATIENTS WITH AGE-RELELATED GERIATRIC DISEASES (노인성 전신질환 입원환자에서 치성감염 관리에 관한 임상적 연구)

  • Yoo, Jae-Ha;Choi, Byung-Ho;Han, Sang-Kwon;Chung, Won-Gyun;Noh, Hie-Jin;Jang, Sun-Ok;Kim, Jong-Bae;Nam, Ki-Young;Chung, Jae-Hyung;Kim, Byung-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.5
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    • pp.414-421
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    • 2004
  • This is a reprospective study on the care of odontogenic infections in admission patients with geriatric diseases. The study was based on a series of 480 patients at Dong San Medical Center, Wonju Christian Hospital and Il San Health Insurance Hospital, From Jan. 1, 2000, to Dec. 31, 2002. The Obtained results were as follows: 1. The systemic malignant tumor was the most frequent cause of the geriatric diseases with odontogenic infectious diseases, and refractory lung disease, systemic heart disease, type II diabetes mellitus, cerebrovascular disease, bone & joint disease, senile psychologic disease were next in order of frequency. 2. Male prediction(57.5%) was existed in the odontogenic infectious patients with geriatric diseases. But, there were female prediction in senile psychologic disease, systemic heart disease and cerebrovascular disease. 3. The most common age group of the odontogenic infectious patient with geriatric disease was the sixty decade(47.9%), followed by the seventy & eighty decade in order. 4. In the contents of chief complaints on the odontogenic infectious patients with geriatric disease, peak incidence was occurred as toothache(52.7%), followed by extraction wish, tooth mobility, oral bleeding, oral ulcer, fracture of restoration, gingival swelling in order. 5. In the diagnosis group of odontogenic infectious diseases, periodontitis, pulpitis & periapical abscess were more common. 6. In the treatment group of odontogenic infectious diseases, the most frequent incidence(34.2%) was showed in primary endodontic treatment (pulp extirpation, occlusal reduction and canal opening drainage) and followed by scaling, incision & drainage, only drugs, pulp capping, restoration in order.

CEMENTOMAS OF THE MANDIBLE;REPORT OF TWO CASES & DISCUSSION (하악골에 발생된 백아종 2예)

  • Yoo, Jae-Ha;Ryu, Soo-Jang
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.12 no.1
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    • pp.148-157
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    • 1990
  • The cementomas are derived from the periodontal ligament and a diversified group of nonrelated lesions producing cementum-like material. The diagnostic term, Cementoma, has encompassed several unrelated lesions : periapical cemental dysplasia, benign (true) cementoblastoma, cementifying fibroma and familial multifle (gigantiform) cementoma. The authors treated one case of benign cementoblastoma & the other of cementifying fibroma by conservative enucleation & curettage. By follow up check of the patient, We obtained of good result without any signs of recurrence of the lesions.

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The LCOS Optical Engine Evaluation and the Temperature Measurement

  • Mo, Chi-Neng;Chen, Ching-Chung;Wu, Shih-Min;Liu, Chia-Lin;Chen, Hun-Wei;Chang, Ming
    • 한국정보디스플레이학회:학술대회논문집
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    • 2004.08a
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    • pp.947-950
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    • 2004
  • The discusses of this study is that we combined the systems with a new type of LCOS optical engine and the latest color management of LMS to measure the distribution of illuminance, chromaticity and Contrast on the big size of the screen and we will focus on the distribution of temperature at the surface of the PS converter under the heat to evaluate the effectiveness of the heat dissipated faculty of the optical engine system. It will support that we design and fabricate the optics devices and optical engines.

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Selection of Environmentally Conscious Manufacturing's Program Using Multi-Criteria Decision Making: A Case Study in Electronic Company

  • Sutapa, I. Nyoman;Panjaitan, Togar W.S.
    • Industrial Engineering and Management Systems
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    • v.10 no.2
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    • pp.123-127
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    • 2011
  • Nowadays, green purchasing, stop global warming, love the mother earth, and others that related to environment become hot issues. Manufactures industries tend to more active and responsive to those issues by adopting green strategies or program like Environmentally Conscious Manufacturing (ECM). In this article, an electronic company had applied 12 ECM Program and tries to choose one of those programs using 6 criteria, such as total cost involved, quality, recyclable material, process waste reduction, packaging waste reduction, and regulation compliance. By using multi-criteria decision making model, i.e. Analytical Hierarchy Process (AHP), Technique for Order Preference by Similarity to Ideal Solution (TOPSIS), and Modified TOPSIS methods, the ECM Program 9 (Open pit) is the best option.

New Attributes and Variables Control Charts under Repetitive Sampling

  • Aslam, Muhammad;Azam, Muhammad;Jun, Chi-Hyuck
    • Industrial Engineering and Management Systems
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    • v.13 no.1
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    • pp.101-106
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    • 2014
  • New control charts under repetitive sampling are proposed, which can be used for variables and attributes quality characteristics. The proposed control charts have inner and outer control limits so that repetitive sampling may be needed if the plotted statistic falls between the two limits. Particularly, the new np and variable X-bar control charts under repetitive sampling are considered in detail. The in-control and out-of-control average run lengths are analyzed according to various process shifts. The performance of the proposed control charts is compared with the existing np and the X-bar control charts in terms of the average run lengths.

A Time Truncated Two-Stage Group Sampling Plan for Weibull Distribution

  • Aslam, Muhammad;Jun, Chi-Hyuck;Rasool, Mujahid;Ahmad, Munir
    • Communications for Statistical Applications and Methods
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    • v.17 no.1
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    • pp.89-98
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    • 2010
  • In this paper, a two-stage group sampling plan based on the time truncated life test is proposed for the Weibull distribution. The design parameters such as the number of groups and the acceptance number in each stage are determined by satisfying the producer's and consumer's risks simultaneously when the group size and the test duration are specified. The acceptable reliability level is expressed by the ratio of the true mean life to the specified life. It was demonstrated from the comparison with single-stage group sampling plans that the proposed plan can reduce the average sample number or improve the operating characteristics.

Effect of substrates on the geometries of as-grown carbon coils

  • Park, Semi;Kim, Sung-Hoon;Kim, Saehyun;Jo, Insu
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2012.11a
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    • pp.163-164
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    • 2012
  • Carbon coils could be synthesized using $C_2H_2/H_2$ as source gases and $SF_6$ as an incorporated additive gas under thermal chemical vapor deposition system. The substrate with oxygen incorporation and the substrate without oxygen incorporation were employed to elucidate the effect of substrate on the formation of carbon coils. The characteristics (formation densities, morphologies, and geometries) of the deposited carbon coils on the substrate were investigated. In case of Si substrate, the microsized carbon coils were dominant on the substrate surface. While, in case of oxygen incorporated substrate, the nanosized carbon coils were prevail on the substrate surface. The cause for the different geometry formation of carbon coils according to the different substrates was discussed in association with the different thermal expansion coefficient values between the substrate with oxygen incorporation and the substrate without oxygen incorporation.

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