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The Relationships among Chemotherapy-Induced Nausea and Vomiting (CINV), Non-Pharmacological Coping Methods, and Nutritional Status in Patients with Gynecologic Cancer (부인암 환자의 항암화학요법으로 인한 오심과 구토, 비약물적 대처방법과 영양상태간의 관계)

  • Lee, Haerim;ChoiKwon, Smi
    • Journal of Korean Academy of Nursing
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    • v.47 no.6
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    • pp.731-743
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    • 2017
  • Purpose: Chemotherapy-induced nausea and vomiting (CINV) can cause severe malnutrition. However, relationships between CINV levels, non-pharmacological coping methods, and nutritional status of female cancer patients have rarely been investigated. Therefore, this study aimed to analyze their relationships in gynecologic cancer patients. Methods: Participants receiving a highly and moderately emetogenic chemotherapy were recruited. The level of CINV was assessed using a numeric rating scale. Coping methods were determined using multiple-choice self-report questionnaires and categorized into seven types for statistical analysis. Nutritional status was evaluated using biochemical and anthropometric parameters. Results: Among all the 485 patients, 200 eligible inpatients were included. Despite the administration of prophylactic antiemetics, 157 patients (78.5%) still experienced CINV, and several used nonmedically recommended coping methods, such as just enduring the symptom or rejecting food intake. A total of 181 patients (90.5%) had nutritional disorders. Although the level of CINV was indirectly related to the occurrence of nutritional disorders, patients who rejected food (${\beta}=1.57$, p=.023) and did not use physical measures (${\beta}=-1.23$, p=.041) as coping methods were under the high risk of nutritional disorders. Conclusion: Korean gynecologic cancer patients had high levels of CINV and were at high risk of nutritional disorders, which may be related to the use of nonscientific coping methods, possibly due to cultural backgrounds and lack of proper nutritional program. Therefore, developing a culturally appropriate educational program for the cancer patients with CINV is urgently needed.

Comparative Review of Pharmacological Treatment Guidelines for Bipolar Disorder (양극성 장애의 약물치료 가이드라인 비교)

  • Seoyeon Chin;Hyoyoung Kim;Yesul Kim;;Bo-young Kwon;Boyoon Choi;Bobae Lee;Jiye Lee;Chae-Eun Kwon;Yeongdo Mun;Kaveesha Fernando;Ji Hyun Park
    • Korean Journal of Clinical Pharmacy
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    • v.33 no.3
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    • pp.153-167
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    • 2023
  • Objective: Bipolar disorder displays a spectrum of manifestations, including manic, hypomanic, depressive, mixed, psychotic, and atypical episodes, contributing to its chronic nature and association with heightened suicide risk. Creating effective pharmacotherapy guidelines is crucial for managing bipolar disorder and reducing its prevalence. Treatment algorithms grounded in science have improved symptom management, but variations in recommended medications arise from research differences, healthcare policies, and cultural nuances globally. Methods: This study compares Korea's bipolar disorder treatment algorithm with guidelines from the UK, Australia, and an international association. The aim is to uncover disparities in key recommended medications and their underlying factors. Differences in CYP450 genotypes affecting drug metabolism contribute to distinct recommended medications. Variances also stem from diverse guideline development approaches-expert consensus versus metaanalysis results-forming the primary differences between Korea and other countries. Results: Discrepancies remain in international guidelines relying on meta-analyses due to timing and utilized studies. Drug approval speeds further impact medication selection. However, limited high-quality research results are the main cause of guideline variations, hampering consistent treatment conclusions. Conclusion: Korea's unique Delphi-based treatment algorithm stands out. To improve evidence-based recommendations, large-scale studies assessing bipolar disorder treatments for the Korean population are necessary. This foundation will ensure future recommendations are rooted in scientific evidence.

Osteomyelitis of Mandibular Condyle : A Case Report in 9-year-old Child (9세 소아에서 발생한 하악과두의 골수염)

  • Lee, Kyung-Eun;Choi, Soon-Jeong;Suh, Bong-Jik
    • Journal of Oral Medicine and Pain
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    • v.34 no.3
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    • pp.333-340
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    • 2009
  • Osteomyelitis means inflammation of the bone marrow. It usually begins in the medullary cavity, involving the cancellous bone; then it extends and spreads to the cortical bone and eventually to the periosteum. The cause is usually thought to be microbiological. But there still are factors that predispose to produce a possible bone infection such as injuries, syphilis, actionomycosis, chronic kidney failure, alcoholism, malnutrition, radiotherapy, and chemotherapy. Treatment of modalities have been directed toward eradicating microbes and improving circulation in the early stage. In the case presented, surgical debridement and IV antibiotics were the treatment of choice. Osteomyelitis in children is mainly affected in the mandible. And in childhood, the mandibular condyle is regarded as an important center of mandibular growth. Therefore, in young patients, osteomyelitis involving this region may cause a restraint of mandibular development, resulting in facial asymmetry. So diagnosis in the early stage is important in child with osteomyelitis. Recently, we have encountered an interesting case of osteomyelitis of the mandibular condyle in 9-year-old boy. So we present the case and review the literature about osteomyelitis.

ADENOMATOID ODONTOGENIC TUMOR ASSOCIATED WITH AN IMPACTED MANDIBULAR RIGHT LATERAL INCISOR (하악 우측 측절치에 발생한 선양 치성 종양)

  • Park, Mi-Seon;Park, Ho-Won;Lee, Ju-Hyun;Seo, Hyun-Woo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.38 no.4
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    • pp.407-412
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    • 2011
  • Adenomatoid odontogenic tumor(AOT) is an infrequent odontogenic tumor which arise in the jaw. It was considered as a variant of ameloblastoma. The adenomatoid odontogenic tumor is clearly benign and, in contrast to the ameloblastoma, present a very low recurrence. It most often appears in the canine region of the maxilla. The adenomatoid odontogenic tumor is frequently asymptomatic, however it may cause painless swelling. The radiological findings of adenomatoid odontogenic tumor frequently share characteristics of dentigerous cyst and unicystic ameloblastoma. Conservative surgical enucleation and curettage are the treatment of choice. In this case a 10-year-old child was presented with mandibular right lateral incisor in unerupted. Radiographically, the tooth was impacted and a radiolucency was seen in the area. The lesion was enuclated without extraction of the tooth. Bracket was attached on the tooth for orthodontic extrusion installed. Histopathologically adenomatoid odontogenic tumor was revealed.

Local Control after Radiation Therapy for T1-T2 Glottic Carcinoma (T1-T2 성문암의 방사선 치료 성적)

  • Kwon, Byung-Hyun;Kim, Dong-Won
    • Radiation Oncology Journal
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    • v.12 no.3
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    • pp.331-336
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    • 1994
  • Purpose : To assess the effectiveness and problems of the primary radiation therapy and salvage surgery in a series of patients affected by T1-T2NO glottic cancers treated from 1985 to 1991 at the Pusan National University Hospital. Materials and Methods : From 8/85 to 12/91,34 patients affected by early glottic carcinoma histologically proven were treated with curative radiation therapy, Distribution of patients according to T stage was 30 for T1 and 4 for T2. Male to female ratio was 33:1. Age of patients ranged from 31 to 73 with mean age of 58 years. All of the patients were treated with radical radiation with total tumor dose of 63-75. 3Gy(median 68.2Gy), of 5 weekly fractions of 1.8-2Gy and with 6MV photon beams through two laterally opposed fields. Results : The overall 5-year local control rates were $74\%$(8/30) for Tl, and $25\%$(3/4) for T2. The main cause of failure was progression or recurrence in T(10/11). One failures were observed in T and N at the same time. Of these 11 patients, 9($81\%$) were salvaged with surgery, After surgical salvage of radiation failures, the 5-year survival rates were $96\%$ for T1 and $75\%$ for T2. Among the survivors, $73\%$ of T1 and $33\%$ of T2 were able to preserve the larynx. Conclusion : It can be concluded that radiotherapy is the first choice in the treatment of glottic T1 carcinoma.

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Utilization of Medical Assistance Patients in Nursing Hospital (의료급여환자의 요양병원 이용에 관한 연구)

  • Lee, Yong-Jae
    • The Journal of the Korea Contents Association
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    • v.17 no.5
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    • pp.366-375
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    • 2017
  • The purpose of this study is to analyze the use of hospital, hospitalization, medical service, discharge and power of medical care patients who are concerned about moral hazard. We conducted focus group interview with 3 medical care patients and their families and 5 workers who had worked for more than 4 years in a nursing hospital. The main results and implications are as follows. First, admission to nursing hospitals was mostly based on the linkage between the medical institutions and the competition to attract the patients rather than the choice of the patients. Second, the main cause of the long-term hospitalization of medical assistance patients was the lack of social protection measures such as absences of residence and care giver, although there are factors that cause moral hazard such as low self-pay. Third, most of the patients were in need of treatment, but they were admitted to the hospital even though their needs were not higher than those of the health insurance patients. Fourth, the rehabilitation service is the mainstay of the medical service of the nursing hospital, and the roles of nursing staff and care givers are important. Fifth, medical care patients are paying medical expenses for nursing hospitals due to cost of living and family support, but they are exempted from the hospital expenses or the burden of their own expenses in the hospital. Sixth, public institutions and social welfare institutions have not managed continuously since commissioning patients to nursing hospitals and have neglected the connection with community services after discharge.

A Case of Pulmonary Endometriosis Resected by Video-Assisted Thoracoscopic Surgery (흉강경술로 제거한 폐 자궁내막증 (Pulmonary Endometriosis) 1예)

  • Ham, Hyoung Suk;Chung, Man Pyo;Lee, Byung-Wook;Han, Kyung Hoon;Kim, Hojoong;Han, Joungho;Shim, Yong Mog;Kwon, O Jung
    • Tuberculosis and Respiratory Diseases
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    • v.56 no.5
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    • pp.542-549
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    • 2004
  • Catamenial hemoptysis is a rare condition caused by thoracic endometriosis that presents as tracheobronchial or pulmonary endometriosis. While hormonal treatment may cause virilization and sterility, due to the antiestrogenic effect, its surgical removal via thoracotomy is a particularly invasive procedure and is not recommended as the first choice treatment in young woman. Successful surgical removal by video-assisted thoracoscopic surgery (VATS) has recently been reported, and may be indicated for young patients who at some stage would like to become pregnant. Herein, a case of a 25-year-old unmarried woman with catamenial hemoptysis, cured by VATS, is reported.

The Relationship Between Congestion Pricing and In-vehicle Crowding Level in Public Transport (혼잡통행료 징수와 대중교통 차내 혼잡수준의 관계)

  • YU, Sang-Gyun;BAE, Gi-Mok
    • Journal of Korean Society of Transportation
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    • v.34 no.6
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    • pp.510-522
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    • 2016
  • In studies involving public transport, social welfare improvement is simply explained by the increase in public transport demand. However, the increase in the demand for public transport is mostly observed by the change in the frequency of public transport service, and in-vehicle crowding in public transport has not been an object of concern. This study examines and tries to reveal the cause of the changes of the social welfare and in-vehicle crowding of the changing public transport from imposing congestion pricing. We observe that congestion pricing increases in-vehicle crowding in public transport. This predictable phenomenon is more exacerbated in case of not operating bus-only lane. It should be noted that in-vehicle crowding is more increased in suburban, but in First-best toll system it tends to get worse less than it in other congestion pricing systems. We identify that the change of in-vehicle crowding is affected by the change of proximity of the housing to workplace, the number of commuting trips, and unpredictable distortion effect of the congestion charge.

Transcatheter Embolotherapy of Giant Pulmonary Arteriovenous Malformation Using Amplatzer® Vascular Plug (Amplatzer® 혈관폐색장치를 이용한 거대 폐동정맥기형 색전술 1예)

  • Jung, Ki Hwan;Lee, Seung Hwa;Shin, Chol;Kim, Je Hyeong
    • Tuberculosis and Respiratory Diseases
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    • v.67 no.1
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    • pp.52-58
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    • 2009
  • Pulmonary arteriovenous malformation (PAVM) is a rare pulmonary vascular anomaly due to an abnormal communication between the pulmonary artery and vein. The most common presenting symptom is a dyspnea on exertion related to this right-to-left shunt. If left untreated, PAVM has been known to result in serious complications. Incomplete pulmonary capillary network can be the cause of cerebral abscesses and other noninfectious neurological complications, such as stroke and transient ischemic attacks due to paradoxic embolism Transcatheter embolotherapy, using coils or balloons, has replaced surgical resection as the treatment of choice for PAVM. However, the risk of device embolization has limited the use of coil embolotherapy, while the size of PAVM is huge. Recently, Amplatzer$^{(R)}$ Vascular Plug has been proposed as an alternative endovascular occlusion device for arteriovenous malformation. We report a case of 81-year-old male patient with a giant PAVM, which was successfully treated by transcatheter embolotherapy using the Amplatzer$^{(R)}$ Vascular Plug.

A Study on the Domestic Behavioral Patterns of Korean Tourists by the Characteristics of Residences (관광자의 거주지 특성에 따른 관광행태 연구)

  • Song, Young-Chol
    • Journal of the Korean association of regional geographers
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    • v.8 no.1
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    • pp.83-97
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    • 2002
  • In this study we shall compare the differences among Korean tourists' behavioral patterns according to tourists' residences by using statistical techniques on questionnaires for 1,372 tourists around Korea. In conclusion, we found varying degrees of influences among touristic behaviors in relation to residences, We documented 11 out of 14 categories of touristic behaviors in urban/rural areas around Korea. And there were 4 out of 14 categories of those found in provincial areas. Characteristics of urban/rural areas had a significant influence on touristic behaviors compared to provincial areas. Therefore, tour authorities provide for a balanced policy of travel around Korea. As mentioned above, these touristic behaviors had many differences according to urban/rural areas and provinces. We are concerned that these differences are likely to cause psychological disturbances among social classes. I hope that these results will be reflected in the development policies of tourist goods and tour sites.

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