• 한국약용작물학회지
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• 제7권4호
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• pp.316-324
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• 1999

중국에서 약용식물은 서양의학과 동등한 수준으로 인간의 건강증진과 유지 및 치료를 위해 매우 중요한 역할을 수행하고 있는데 본 논문에서는 중국에서 약용식물의 산업적 발달에 관해서 간략히 고찰하였다. 현계 중국에서 약용식물로 이용되고 있는 식물은 11, 118종에 달한다. 이들 약용식물이 가공되지 않고 천연산물로 이용되는 연간 총 생산액은 60억달러에 달하며 조제형태로 이용되는 총 생산액은 30억달러에 달한다. 지금까지 약용식물로부터 100여종 이상의 신약이 개발되었으며 천연자원에 의존하려는 세계적인 추세를 감안한다면 약용식물의 중요성은 더욱 증대할 것이며 산업적 개발이 인류의 건강을 유지하는데 결정적 역할을 할 것으로 기대된다.

• Journal of Pharmaceutical Investigation
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• 제17권1호
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• pp.22-30
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• 1987

Evaluation method of crude drug preparations was studied in Saengmaek-san. Zig-zag TLC scanning profiles and high performance liquid chromatograms were obtained from Saengmaek-san and its each crude drug. A method using TLC densitometry and high performance liquid chromatography was established for the precise determination of ginsenoside $Rb_1$ in Saengmaek-san containing Ginseng Radix. Consequently, ginsenosicle $Rb_1$ content was 0.45-0.48 mg per g of Saengmaek-san. This method was found to be useful for the quality evaluation of oriental medicinal preparations.

• 대한본초학회지
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• 제23권4호
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• pp.171-177
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• 2008

Objectives: This study presents a reversed-phase high-performance liquid chromatography- pulsed amperometric detection(RP-HPLC-PAD) method for the determination of puerarin and daidzin in Puerariae Radix extract and Chinese medicinal preparations. Methods: Chromatographic separation was performed using a 10% acetonitrile with a reversed-phase column(Unison UK-C18, $100mm{\times}2.0mm$ I.D.; $3{\mu}m$). The analyses were detected by pulsed amperometric detector(PAD) in alkaline conditions by combining with post-column NaOH solution. Geniposide was used as an internal standard. Results: The limit of detection(S/N=3) and the limit of quantification(S/N=10) were 0.025 ng, 0.075 ng for puerarin, and 0.05 ng, 0.15 ng for daidzin, respectively. The intra- and inter-day precisions(RSDs) were less than 6.5% and average recoveries of puerarin were 99.7-101.3% and those of daidzin were 101.0-102.8%. Conclusions: According to above results, we developed a determination method for puerarin and daidzin in Puerariae Radix with high sensitivity and selectivitely.

• 동의생리병리학회지
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• 제31권3호
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• pp.153-158
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• 2017

As social interest in acne treatment has grown, various external preparations have been developed and studied. So, we investigated the external prescription which can treat acne in medical classics, then reviewed and divided it by dynasty. The data for analysis of Herbal formula was taken from 'medicine Dictionary of traditional Chinese medicine prescriptions(中醫方劑大辭典)'. 31 external medicines were searched, 3 were before song(宋) dynasty, 11 were Song(宋) dynasty, 11 were Yuan(元) dynasty, 7 were Ming(明) dynasty and 7 were Qing(淸) dynasty. The recipe and usage were only making them pill(丸) and paste(膏) using grinded medicinal herbs, then rubbing to face. As the age developed, unique manufacturing process(i.e fermentation method), and usage(i.e time-based usage, herbal medicine extracts for wash) were proposed. The external application with oriental medicine for acne used with Angelicae Gahuricae Radix(n=12), Bletillae Rhizoma(n=8), Syzygii Flos, Saposhnikoviae Radix(n=7) and so on. In particular, Bletillae Rhizoma was searched with high frequency in this study, but it was not included or studied in patent composition. The results of this study will provide basic data for future experiments and clinical studies.