• Title/Summary/Keyword: Chinese Medical Academy

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A Comparative Study of Medical Data Classification Methods Based on Decision Tree and System Reconstruction Analysis

  • Tang, Tzung-I;Zheng, Gang;Huang, Yalou;Shu, Guangfu;Wang, Pengtao
    • Industrial Engineering and Management Systems
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    • v.4 no.1
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    • pp.102-108
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    • 2005
  • This paper studies medical data classification methods, comparing decision tree and system reconstruction analysis as applied to heart disease medical data mining. The data we study is collected from patients with coronary heart disease. It has 1,723 records of 71 attributes each. We use the system-reconstruction method to weight it. We use decision tree algorithms, such as induction of decision trees (ID3), classification and regression tree (C4.5), classification and regression tree (CART), Chi-square automatic interaction detector (CHAID), and exhausted CHAID. We use the results to compare the correction rate, leaf number, and tree depth of different decision-tree algorithms. According to the experiments, we know that weighted data can improve the correction rate of coronary heart disease data but has little effect on the tree depth and leaf number.

The Impact of Self-Efficacy on Nurses' Well-Being: Does Digital Competence Matter?

  • Li, Yali;Jing, Qi;Feng, Taiwen;Yang, Xiaoling
    • Journal of Korean Academy of Nursing
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    • v.53 no.4
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    • pp.385-396
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    • 2023
  • Purpose: Drawing on person-environment fit theory and social cognitive theory, this study aimed to examine how self-efficacy affects nurses' workplace well-being via person-job fit and the moderating role of digital competence. Methods: A two-wave survey was conducted to collect data. Data were collected from six hundred and ninety-five nurses at three Chinese hospitals between May 2022 and September 2022. We employed hierarchical regression analysis and bootstrapping to analyze the data. Results: Self-efficacy positively influenced person-job fit (β = .55, p < .001), which positively affected nurses' workplace well-being (β= .32, p < .001). Person-job fit mediated the effect of self-efficacy on nurses' workplace well-being. Additionally, digital competence strengthened the positive impact of self-efficacy on person-job fit (β = .12, p < .001). Conclusion: Recruiting nurses with both self-efficacy and digital competence benefits hospitals. It is critical for nurses to improve their digital competence for achieving person-job fit and attaining workplace well-being in the post-coronavirus disease 2019 (COVID-19) era.

Time Trends of Ovarian Cancer Incidence in China

  • Wang, Bing;Liu, Shu-Zheng;Zheng, Rong-Shou;Zhang, Fang;Chen, Wan-Qing;Sun, Xi-Bin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.191-193
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    • 2014
  • The aim of this study was to examine the trend of ovary cancer incidence from 1999 to 2010 in China and predict the burden up to 2020. Crude incidence, age specific incidence and age-adjusted incidence rates were calculated. Joinpoint regression was performed to obtain estimated annual percentages and Bayesian age-period-cohort modeling was used to predict the incidence rate until the year 2020. In China, the crude rate of ovary cancer was 7.91/100,000 and the age-adjusted rate was 5.35/100,000 overall during period 1999-2010. The rates in urban regions were higher than in rural regions. A significant rising trend during 1999-2006 was followed by a drop during 2006-2010 in age-adjusted rates for urban females. In contrast, constant rise was observed in rural women. The decrease in ovary cancer of urban areas tended to be restricted to women aged 50 years and younger. In contrast, increases of ovary cancer in rural areas appeared in virtually all age groups. Although the age-adjusted incidence rate for ovary cancer was predicted to be reduced after year 2011, the crude rate was likely to be relative stable up to 2020. The burden of ovary cancer in China will continue to be relative stable due to the aging population.

Genome-Wide Transcriptomic Analysis of n-Caproic Acid Production in Ruminococcaceae Bacterium CPB6 with Lactate Supplementation

  • Lu, Shaowen;Jin, Hong;Wang, Yi;Tao, Yong
    • Journal of Microbiology and Biotechnology
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    • v.31 no.11
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    • pp.1533-1544
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    • 2021
  • n-Caproic acid (CA) is gaining increased attention due to its high value as a chemical feedstock. Ruminococcaceae bacterium strain CPB6 is an anaerobic mesophilic bacterium that is highly prolific in its ability to perform chain elongation of lactate to CA. However, little is known about the genome-wide transcriptional analysis of strain CPB6 for CA production triggered by the supplementation of exogenous lactate. In this study, cultivation of strain CPB6 was carried out in the absence and presence of lactate. Transcriptional profiles were analyzed using RNA-seq, and differentially expressed genes (DEGs) between the lactate-supplemented cells and control cells without lactate were analyzed. The results showed that lactate supplementation led to earlier CA p,roduction, and higher final CA titer and productivity. 295 genes were substrate and/or growth dependent, and these genes cover crucial functional categories. Specifically, 5 genes responsible for the reverse β-oxidation pathway, 11 genes encoding ATP-binding cassette (ABC) transporters, 6 genes encoding substrate-binding protein (SBP), and 4 genes encoding phosphotransferase system (PTS) transporters were strikingly upregulated in response to the addition of lactate. These genes would be candidates for future studies aiming at understanding the regulatory mechanism of lactate conversion into CA, as well as for the improvement of CA production in strain CPB6. The findings presented herein reveal unique insights into the biomolecular effect of lactate on CA production at the transcriptional level.

Antiserum Preparation of Recombinant Sweet Potato Latent Virus-Lotus (SPLV-Lotus) Coat Protein and Application for Virus-Infected Lotus Plant Detection

  • He, Zhen;Dong, Tingting;Chen, Wen;Wang, Tielin;Gan, Haifeng;Li, LiangJun
    • The Plant Pathology Journal
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    • v.36 no.6
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    • pp.651-657
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    • 2020
  • Lotus is one of the most important aquatic vegetables in China. Previously, we detected sweet potato latent virus from lotus (SPLV-lotus) and found that it has highly significant sequence diversity with SPLV-sweet potato isolates (SPLV-sp). Here, we developed serological methods for the detection of SPLV-lotus in Chinese lotus cultivation areas. Based on the high sensitivity of SPLV-lotus coat protein antiserum, rapid, sensitive and large-scale diagnosis methods of enzyme-linked immunosorbent assay (ELISA) and dot blot in lotus planting area were developed. The established ELISA and dot blot diagnostic methods can be used to detect SPLV-lotus from samples successfully. And our results also showed that the SPLV-lotus and sweet potato isolates appeared clearly distinction in serology. Our study provides a high-throughput, sensitive, and rapid diagnostic method based on serology that can detect SPLV on lotus, which is suggested to be included in viral disease management approach due to its good detection level.

Occupational Health Protection for Health Workers in China With Lessons Learned From the UK: Qualitative Interview and Policy Analysis

  • Xu, Huan;Zhang, Min;Hudson, Alan
    • Safety and Health at Work
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    • v.12 no.3
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    • pp.304-310
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    • 2021
  • Background: Healthcare settings have been recognized among the most hazardous places to work. Based on the five categories of occupational hazards that were identified by the ILO and WHO, this study aimed to analyze policy framework relevant to occupational health protection of health workers (HWs) in public health service in China, then discussed how to share the experience of the National Health Service (NHS) England for improvement. Methods: Based on policy learning theories, policy analysis and qualitative interview were used in this study. Results: In the Chinese public health service, at least five laws related to the regulation of occupational health protection for HWs; however, enforcement of relevant laws was separated and multi-centered; the national monitoring system, which targeted to occupational hazards and health outcome for HWs in China, had yet to be developed; the top three priorities were workplace violence, bloodborne pathogens, and musculoskeletal disorders; national strategies included Security Hospital, and Healthy China 2030. In NHS England, three laws were fundamental; several monitoring systems had been set up, including NHS Staff Survey, Commissioning for Quality and Innovation incentive scheme; mental health, musculoskeletal problem, and nutrition disorder and overweight were raised great concern; Health and Safety, and NHS Healthy Workforce Program were critical nationwide strategies. Conclusion: There were several similarities as well as differences between the Chinese public health system and NHS England, which laid foundation of learning by China. Recommendations of improving occupational health policies in China were provided, based on the lessons learned from the NHS England.

Impact and Evaluation of International Cancer Control Congresses

  • Sarwal, Kavita;Trapido, Edward J.;Sutcliffe, Simon;Qiao, You-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.1159-1163
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    • 2013
  • International meetings on various aspects of cancer- its etiology, its diagnosis, its treatment, its palliation, and its prevention and control are held frequently. Many have similar themes, and many seek and receive the same speakers and audiences. A fundamental question arises: what difference does any individual meeting/congress/conference make or add to our understanding of the relevant issues? While many meetings conduct evaluations at the end of the Congress, few use evaluation as a tool to guide design, implementation, and evaluation of both short and long term impacts, and address the question of "what difference did the Congress make". The International Cancer Control Congresses, which are held biennially in different regions of the world, took the opportunity to use evaluation in this way, and ask the relevant questions. This paper describes that evaluation session of the ICCC4, held in Seoul, Korea in November 2011, which was part of the larger evaluation issue.

MECHANISM OF CHEMOPREVENTION OF CARCINOGENIC HETEROCYCLIC AMINES BY TEA POLYPHENOLS AND COFFEE LIPIDS

  • Fred F. Kadlubar;Lin, Dong-xin;Daniel A. Casciano
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.41-42
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    • 2001
  • The chemopreventive effect of tea against 2-amino-l-methyl-6-phenylimidazo[4, 5-b ]pyridine (PhIP)-DNA adduct formation and its mechanism were studied. Rats were exposed to freshly prepared aqueous extracts of green tea (3% w/v) as the sole source of drinking water for 10 days prior to administration with a single dose of PhIP (10 mg/kg body wt) by oral gavage. PhIP-DNA adducts in the liver, colon, heart, and lung were measured using the $^{32}$ P-postlabelling technique.(omitted)

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A New Cycloartane Glycoside from Camptosorus sibiricus Rupr.

  • Ning-Li;Xian-Li;Peng-Zhang;Li, Zhan-Lin;Yang, Shi-Lin;Wang, Jin-Hui
    • Archives of Pharmacal Research
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    • v.27 no.7
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    • pp.727-729
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    • 2004
  • A new cycloartane glycoside was isolated from the dried whole herbs of Camptosorus sibiricus Rupr By means of chemical (hydrolysis) and spectroscopic methods (IR, 1D, and 2D NMR, ESI-MS), the structure was established as $3{\beta}$, $7{\beta}$, $24{\beta}$, 25, 30-pentahydroxycycloartane-3-O-${\beta}$-D-glucopyranoside-24-O-${\beta}$-D-glucopyranoside (1).