• The Journal of Korean Academy of Sensory Integration
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• v.16 no.2
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• pp.1-14
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• 2018

Objective : The present study investigated the effects of group play activities based on Ayres Sensory $Integration^{(R)}$ (ASI) on sensory processing ability, social skill ability and self-esteem of low-income children with attention deficit hyperactivity disorder (ADHD). Methods : A total of 20 low-income participants with children with ADHD were recruited and divided into an experimental group (n=10) and a control group (n=10). Sensory processing ability was measured via the Short Sensory Profile (SSP). Social skill ability was measured via the Social Skills Rating System (SSRS). To measure self-esteem, the Rosenberg's self- esteem scale was used. The experimental group received the $ASI^{(R)}$ group play activities for 50 minutes, twice per week for six weeks, while the control group did not receive an intervention. Level of significance of all statistical analyses was .05. Results : Social skill ability (F=4.443, p=.05), cooperation (F=5.328, p=.035) and self-esteem (F=5.358, p=.033) differed significantly between groups after the intervention. Conclusion : Our findings indicate that the group play activities based on $ASI^{(R)}$ are effective in improving social skill ability and self-esteem. This study provided a theoretical basis for the claim that sensory integration therapy should be applied in general elementary schools.

• International Journal of Human Ecology
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• v.12 no.2
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• pp.95-107
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• 2011

Recent intervention studies document that mother-child dyads with higher levels of Emotional Availability (EA) report fewer child behavior problems than dyads with lower EA. This study examines possible mechanisms that lead to this result by looking at the parent-child micro-system as a whole, with multi-dimensional relationships that include individual differences in the child's cognitive level, parental stress and parent-child interaction. A total 67 children ($1{\frac{1}{2}}$ to $5\;{\frac{1}{2}}$ years of age) and their mothers were videotaped during 30-min play interactions. Interactions were coded using the Emotional Availability (EA) Scales (Biringen, Robinson, & Emde, 1998). Mothers completed Parenting Stress Index-Short Form, Child Behavior Checklist/$1\;{\frac{1}{2}}$ - 5, and the Ages Stages Questionnaire. The findings showed that mothers with higher levels of parenting stress were more likely to be intrusive, hostile, insensitive, and had a tendency to do less structuring in play. The children of stressed and depressed mothers demonstrated less involvement and responsiveness towards their mothers. Children who have higher dyadic EA scores experienced fewer externalizing and internalizing problems. SEM analyses results showed a mediation effect of EA on the association between maternal psychological well-being and child behavior problems. Fewer deficits in child communication skills and problem solving skills that were related with lower parenting stress and depression were associated with higher maternal non-intrusiveness. Higher non-intrusiveness was related to less internalizing and externalizing problems that indicated the indirect effect of child cognitive competence. Possible interpretations and implications of the study findings are discussed.

• Convergence Security Journal
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• v.13 no.2
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• pp.55-66
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• 2013

Child abuse is urgent and important issue that dominates child's life and influences lifetime. Especially, the children who use the daycare facilities are vulnerable to ill-treatment because of young age, resulting in being serious in after-affect of its abuse. In case of being serious, a child may lead to death. Also, the main agent is absent that will speak for the abused child's injustice and ask for help. Thus, the child abuse has many cases of coming to a close always as children's miserable sacrifice. Hence, the child care center employees will need to recognize a fact that the child abuse is not a private problem within home any more, but a serious crime, and to be confronted by early finding and reporting abuse as a responsible person for report. When the child care center employees fully perform a role as a responsible person for report of child abuse and when the cooperation between child protection service and day care center is properly made after report, the daycare facilities will be able to play a role of child safety network, which protects children of being put in the exclusion.

• Journal of Genetic Medicine
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• v.12 no.1
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• pp.44-48
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• 2015

Townes-Brocks syndrome (TBS) is a rare genetic disorder characterized by the classic triad of congenital anomalies of the anus, thumbs, and ears, with variable expressivity. Additionally, renal malformations, cardiac anomalies, and endocrine and eye abnormalities can accompany TBS, although less frequently. TBS is inherited in an autosomal dominant fashion; however, about 50% of patients have a family history of TBS and the remaining 50% have de novo mutations. SALL1, located on chromosome 16q12.1, is the only causative gene of TBS. SALL1 acts as a transcription factor and may play an important role in inducing the anomalies during embryogenesis. Clinical features of TBS overlap with those of other multiple anomaly syndromes, such as VACTERL syndrome, Baller-Gerold syndrome, Goldenhar syndrome, cat eye syndrome, and Holt-Oram syndrome. Consequently, there are some difficulties in differential diagnosis based on clinical manifestations. Herein, we report a Korean family with two generations of TBS that was diagnosed based on physical examination findings and medical history. Although the same mutation in SALL1 was identified in both the mother and the son, they displayed different clinical manifestations, suggesting a phenotypic diversity of TBS.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.35 no.9
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• pp.65-75
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• 2019

This study aims at analyzing the therapeutic design characteristics implemented in the indoor atriums of the outpatient areas in four children's hospitals in London and San Francisco. A mixed-method approach was used to examine the spatial configurations and design elements in the atriums, while a literature review was conducted to understand the therapeutic design characteristics relevant to atrium spaces and children's healthcare facilities. The spatial design and the pattern of use of the atrium in each hospital were studied during field visits and interviews with the hospital management staff. Based on the literature review and the observations from the field study, a Visibility Graphic Analysis was chosen to examine the visibility, accessibility, and intelligibility of the spatial configurations in the atriums of each hospital. In addition, the openness, restfulness, and vibrant ambience of the design elements in the atriums of each hospital were investigated by surveying fifty-two design professionals on the quality of the design elements in the atriums. A spatial configuration analysis, confirmed that all the atrium spaces had high visibility, accessibility, and intelligibility due to their high connectivity, integration, intelligibility, and because the atriums were laid out in the open lobby space, along the major circulation axis, or in the circulation intersection. In the survey of the design element evaluation, all atriums proved to be appropriate in terms of openness, while the adequacy of restfulness and vibrant ambience differed depending on the hospitals. Notably, location and orientation, access, natural light, outdoor view, and play facilities were found significant environmental design elements determining the successful implementation of the therapeutic design in the atriums. The observations from the aforementioned are further discussed to enhance the therapeutic design quality of atrium spaces in children's hospitals.

• Molecules and Cells
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• v.46 no.4
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• pp.219-230
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• 2023

Down syndrome (DS) is the most common autosomal aneuploidy caused by trisomy of chromosome 21. Previous studies demonstrated that DS affected mitochondrial functions, which may be associated with the abnormal development of the nervous system in patients with DS. Runt-related transcription factor 1 (RUNX1) is an encoding gene located on chromosome 21. It has been reported that RUNX1 may affect cell apoptosis via the mitochondrial pathway. The present study investigated whether RUNX1 plays a critical role in mitochondrial dysfunction in DS and explored the mechanism by which RUNX1 affects mitochondrial functions. Expression of RUNX1 was detected in induced pluripotent stem cells of patients with DS (DS-iPSCs) and normal iPSCs (N-iPSCs), and the mitochondrial functions were investigated in the current study. Subsequently, RUNX1 was overexpressed in N-iPSCs and inhibited in DS-iPSCs. The mitochondrial functions were investigated thoroughly, including reactive oxygen species levels, mitochondrial membrane potential, ATP content, and lysosomal activity. Finally, RNA-sequencing was used to explore the global expression pattern. It was observed that the expression levels of RUNX1 in DS-iPSCs were significantly higher than those in normal controls. Impaired mitochondrial functions were observed in DS-iPSCs. Of note, overexpression of RUNX1 in N-iPSCs resulted in mitochondrial dysfunction, while inhibition of RUNX1 expression could improve the mitochondrial function in DS-iPSCs. Global gene expression analysis indicated that overexpression of RUNX1 may promote the induction of apoptosis in DS-iPSCs by activating the PI3K/Akt signaling pathway. The present findings indicate that abnormal expression of RUNX1 may play a critical role in mitochondrial dysfunction in DS-iPSCs.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.529-538
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• 2017

This study examines the effects of reading and story sharing through fairy tales on young children's character development in their role play using natural materials. To achieve this, 40 5-year-old children at early childhood educational institutes in Daejeon were tested 16 times for 8 weeks. The results were as follows. First, their role plays using natural objects through reading and talking had a positive effect on their personality cultivation. Second, there was no experimental difference in their prudence and filial piety of basic behavioral items, but their cleanliness and patience were proven effective in the experiment. Third, all their justice, conscience and service indicating their sociality-related friendship, kindness, gentleness and morality were proven effective in the experiment, which their role plays using natural objects through reading and story sharing through fairy tales had an educational effect on improving their sociality and morality through peer interaction. This suggests that their mind to improve social virtues with an exchange of emotions, particularly, treat natural role play in a friendly way, their public promises to cherish life, and their ethical virtues to obey the rules in the process of consideration, appreciation, understanding and help through mutual communication and cooperation in forest experience activities are very effective from an educational perspective.

• Journal of the Korean housing association
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• v.26 no.3
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• pp.25-32
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• 2015

Apartment complex has become the major residental type of the urban structure. apartment complex has started to equip various subsidiary welfare facilities recently. environmental planning for play space has especially been important due to the growing attention over children's emotional development. In this study, arrangement types for play spaces in apartments to invigorate communication had been analyzed focusing on physical environment. based on previous studies, the arrangement of subsidiary welfare facilities can be categorized into dispersal type, concentrative type, affiliated type, and affiliated concentration type, and the elements to invigorate communication consist of circulative elements which contain location of play space and affiliated facility, visual elements which contain visual openness, and social elements which draw arrangement types of benches. the result of the analysis devide the arrangement type into concentrative type, affiliated type, and affiliated concentration type. referring to the location of play space, the first, if it is situated outside of apartment complex, theme-centered play space can be equipped to invigorate communication, the second, if it is situated in the center of the complex or outside of the apartment complex, low fence can be applied for free sight, and the last, straight type of bench arrangement should be used in big scale play space, aspectant type and gazebo type of the arrangement can be situated only outside of complex. This research could serve as a baseline of physical environment analysis to invigorate communication for play space in apartment complex.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.6 no.10
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• pp.121-129
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• 2016

The purpose of this study is to explore the child education experiences of married female students who left their children in their home countries. This study consists of two questions. First, what is the meaning of the child in home country for married female students to their foreign student's life? Second, how they do the child education? For this study data was collected from March to May, 2016 through in-depth interviews with 6 married female students who left their children in their home countries to further their studies in Korea. Then, the data was analyzed their cases were analyzed. First, for married female students their children are always in the first place during their life as a foreign student in Korea. Second, their children play a great role in their foreign student life. Third, the child makes them to be exemplary student in their foreign student's life. In addition, children's education is entrusted to those who are raising them in their home country. However, when big decisions have to be made, it is done by the mother. Also, because they feel sorry towards their children they actively reflect the views of the children. Moreover, they often check everything about their children through SNS. Through this study, we expect to less school life's difficulty of foreign married students and it will be helpful material for them to graduate their foreign students' life. The purpose of this study is to explore the child education experiences of married female students who left their children in their home countries.

• Journal of the Korean association of regional geographers
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• v.8 no.4
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• pp.492-512
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• 2002

The daily life activities of primary school children have been increasingly diversified. This research examined the spatio-temporal characteristics of primary school children's daily life activities. The time allocation of primary school children's daily activities was monotonous. They tended to spend most of their time in school activities, private lessons after school, and studying at home. The daily trip to school has been diversified as the result the of increase in the number of double-income families, car owners, facilities for pastime, and educational facilities for private lessons after school. The selection of educational facilities for private lessons was strongly influenced by accessibility to the residence because of the limited time budget of primary school children and the controlled trip behavior by parents. The leisure activities were considered as a minor function and took place in the interval of performances of study-related activities. The high proportion of leisure activities was found in the indoor play. The amount of the time for leisure activity was very insufficient. The spatial range and time budget were strongly influenced by the institutional conditions of parents.