• Tuberculosis and Respiratory Diseases
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• 제63권6호
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• pp.511-514
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• 2007

Mycoplasma pneumoniae에 의한 폐렴의 임상양상은 다양하다고 알려져 있으며, 흉부 방사선 소견상 대부분 기관지 주위 폐렴이나 반점형 폐 침윤 양상을 보이고 폐허탈은 5% 정도로 매우 드물게 발생하는 것으로 되어 있다. 본 저자들은 미열, 두통, 건성 기침, 근육통 등 비정형적인 폐렴의 증상을 보이면서 대엽성 무기 폐로 발현한, 마이코플라즈마 폐렴을 경험하였기에 이를 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제65권4호
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• pp.328-333
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• 2008

박리성 간질성 폐렴은 흡연가에 호발하는 비교적 드문 미만성 간질성 폐질환이다. 박리성 간질성 폐렴은 치료에 대한 반응과 예후가 좋은 질환이나, 재발하는 경우가 있고 치료기간이 명확히 정해져 있지 않으며, 심한 섬유화가 동반되는 경우는 드문 질환이다. 저자들은 흉부 전산화단층 촬영에서 견인성 기관지확장증과 초기의 벌집모양 폐 소견과 함께 미만성 간유리혼탁화를 보이는 환자에서 흉강경하 폐 조직 검사로 박리성 간질성 폐렴을 진단하였고, 치료 종결 후 재발한 박리성 간질성 폐렴을 경험하였기에 이를 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제62권1호
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• pp.67-70
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• 2007

흉선암종은 드문 종격동의 악성 종양으로서 흉선상피세포에서 기원하지만 흉선종과는 조직학적 특징이 다르다. 흉선종이 자가면역질환을 종종 동반하는데 반해 흉선암종에서 자가면역질환이 동반되는 예는 드물다. 국내에서는 흉선암종과 자가면역질환이 동반된 예가 보고된 적이 없는데 저자들은 전신 근육통을 주소로 내원한 49세 남자 환자가 전신홍반루프스와 흉선암종을 동시에 진단받고 항암치료를 시작한 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제81권2호
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• pp.156-162
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• 2018

Background: Eosinophilia is well recognized in specific conditions. The objective of the present study was to determine clinico-radiologic characteristics of eosinophilia and changes in prevalence over 10 years in recipients of private health screening program at a tertiary hospital in Korea. Methods: Data of private health screening program recipients at the health promotion center of Chung-Ang University Hospital from 2004 to 2013 were collected. Health-related questionnaires and laboratory findings of private health screening program with possible relation with eosinophilia were reviewed. Results of enzyme-linked immunosorbent assay (ELISA) for parasite, chest computed tomography, and pulmonary function test were also reviewed. Results: The cumulative prevalence of eosinophilia was 4.0% (1,963 of 48,928). Prevalence of eosinophilia showed a decreased trend from 2004 to 2013. Most cases (96.6%) had mild degree of eosinophilia. Eosinophilic subjects were older and male-predominant. They showed lower levels of forced expiratory volume in 1 second ($FEV_1%$), forced vital capacity (FVC%), and $FEV_1/FVC$ than those without eosinophilia. Eosinophilic subjects showed higher positive rate for common parasite in ELISA than those without eosinophilia. On radiologic findings, consolidation and ground glass opacities were positively associated with the degree of eosinophilia. When eosinophil was classified based on severity, statistically significant correlation between the severity of eosinophil and radiologic abnormalities was found. Conclusion: Eosinophilia is uncommon in healthy population. It usually occurs at a mild degree. Eosinophilic patients have more radiologic abnormalities compared to those without eosinophilia. Such radiologic abnormalities are associated with the severity of eosinophilia.

• Parasites, Hosts and Diseases
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• 제58권1호
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• pp.57-60
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• 2020

During the mobile clinic activities in Tak Province, Thailand, Paragonimus sp. eggs were found in a fecal sample of a 72-year-old Karen resident. Paragonimus DNA was amplified from the stool sample and identified to P. heterotremus. The patient did not have any symptoms. Apparent pulmonary lesion was not found on the chest X-ray. The patient admitted habitual consumption of semi-cooked or roasted waterfall crabs for several years. The waterfall crabs collected from stream near the village were found negative for Paragonimus metacercariae. In northern Thailand, paragonimiasis remains as one of the public health concerns and should be ruled out for asymptomatic pulmonary patients.

• Tuberculosis and Respiratory Diseases
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• 제43권3호
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• pp.461-466
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• 1996

Diffuse alveolar hemorrhage is a very rare manifestation in Henoch-Schoenlein purpura. Recently we experience a case of diffuse alveolar hemorrhage associated with Henoch-Schoenlein purpura which was diagnosed by typical clinical manifestation and renal biopsy. A 25 year old male was admitted due to hemoptysis and dyspnea. Chest X-ray, HRCT and BAL revealed diffuse alveolar hemorrhage. He also had a history of skin rash, polyarthralgia, and hematochezia with abdominal pain. Renal biopsy which was taken for the evaluation of microscopic hematuria showed IgA nephropathy. Under the diagnosis of Henoch-Schoenlein purpura, we treated him with solumedrol pulse therapy, plasma-pheresis and prednisolone with cytoxan. After then he showed marked improvement in clinical manifestation and was discharged with prednisolone and cytoxan.

• Tuberculosis and Respiratory Diseases
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• 제51권6호
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• pp.603-608
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• 2001

저자들은 속립성 폐결핵과 연관되어 급성 경과를 보인 결핵성 뇌수막뇌염 환자에서 뇌혈관 자기공명영상으로 혈관염 소견을 확인하고, 스테로이드의 투여와 중단, 재투여에 따라 뇌증의 증세가 뚜렷히 변하는 임상경과, 증상이 호전된 후 추적한 뇌혈관 자기공명영상에서 혈관 영상이 정상화된 것을 확인할 수 있었던 사례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제72권1호
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• pp.93-97
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• 2012

Propylthiouracil (PTU) is one of the most common drugs used in the treatment of Graves' disease. There are a number of side effects found with PTU use including fever, rash, arthralgia, and flu-like symptoms. Recently antineutrophil cytoplasmic antibodies (ANCA) positive vasculitis after PTU treatment was reported as a rare side effect, which can cause diffuse alveolar hemorrhage and glomerulonephritis. A 45-year-old woman with Graves' disease had been treated with PTU for five months, complained of hemoptysis due to pulmonary alveolar hemorrhage causing anemia, and also had hematuria. Simple chest X-ray and HRCT showed bilateral consolidation and bronchoalveolar lavage fluid revealed alveolar hemorrhage. A serologic test was positive for ANCA against myeloperoxidase and proteinase-3. Such findings suggested that the presence of PTU induced ANCA positive vasculitis. Cessation of PTU and the administration of high dose steroids improved the clinical manifestation, radiologic and serologic findings. We observed ANCA titer serially for 6 years. During the follow up period, ANCA titer decreased slowly and stayed within the acceptable upper normal limit.

• Tuberculosis and Respiratory Diseases
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• 제72권1호
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• pp.37-43
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• 2012

Background: A lung bulla may rarely shrink as a result of an inflammation within the bulla or a closing of a bronchus involved in the inflammation process, which is termed 'autobullectomy'. The purpose of this study was to describe clinical features of patients with regressions of bullae during follow-up. Methods: We retrospectively reviewed the cases and individuals who showed unequivocal evidence of interval regressions in a pre-existing bulla. A total of 477 cases with a bulla >5 cm in diameter were screened manually. Thirty cases with bullae that showed regression during follow-up were selected. Results: Regressions of large bullae occurred in 30 of 477 cases (6.3%). The median age of those patients was 61 (range, 53~66) years and 87% of those patients were men. The main cause of a bulla was emphysema (80%). Among 30 cases, 16 cases had pneumonia in the lung parenchyma of the peribullous area. Another 7 cases had a regressed bulla accompanied by an air-fluid level within the bulla. The remaining 7 cases showed a spontaneous regression of the bulla without such events. Complete regression of a bulla occurred in 25 cases. A follow-up chest-X ray showed that in all cases except one, the bulla remained in a collapsed state after 24 months. Forced expiratory volume in one second ($FEV_1$) improved in 3 cases and the other 2 cases had increased forced vital capacity (FVC). In addition, total lung capacity (TLC) and residual volume (RV) decreased in another 2 cases. Conclusion: Regression of a lung bulla occurred not only after pneumonia or the presence of air-fluid level within the bulla, but also without such episodes. The clinical course of regression of a lung bulla varied. After regression of a bulla, lung function could be improved in some cases.

• Tuberculosis and Respiratory Diseases
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• 제62권2호
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• pp.149-153
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• 2007

폐모세포종은 폐종양으로 매우 드물게 나타나며 드물게 간, 흉외 림프절, 심장으로 전이된다고 보고되고 있다. 본 저자들은 복부의 팽만감과 통증 및 호흡곤란을 주소로 내원한 환자에서 간과 폐의 거대 종괴를 발견하였고, 조직 검사를 통하여 간, 횡격막, 심장 등 다발성 침범을 동반한 폐모세포종으로 진단받은 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.