• 한국가스학회지
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• 제2권2호
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• pp.12-17
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• 1998

급속한 도시가스 보급률의 증가로 인해 국내 도시가스시설에서는 많은 사고가 일어났었다. 이러한 도시가스 사고에 대한 예방 대책으로 여러 관련기관에서는 도시가스의 물성치등 안전 관련 자료들과 도시가스시설에 대한 정보들을 부분적으로 구축$\cdot$관리하고 있다. 하지만 각 기관들이 구축한 정보들을 공유하고 있지 않기 때문에 정보들을 중복되게 구축$\cdot$관리하고 있어 이에 대한 효율성이 결여되어 있다. 따라서 정보 관리와 공유를 효과적으로 할 수 있으며, 정보들을 이용하여 정량적 위험성 평가 및 방재 계획을 지원할 수 있는 지리정보시스템에 관한 연구를 하였다.

• Journal of Microbiology and Biotechnology
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• 제22권2호
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• pp.256-263
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• 2012

A strain of bacterium producing antifungal antibiotic was isolated and identification of the strain was attempted. We could identify the bacterium as being a Bacillus sp., based on morphological observation, physiological characteristics, and 16S rDNA sequence analysis, thus leading us to designate the strain as Bacillus sp. AH-E-1. The strain showed potent antibiotic activity against phytopathogenic and human pathogenic fungi by inducing mycelial distortion and swelling and inhibiting spore germination. The antibiotic metabolite produced by the strain demonstrated excellent thermal and pH (2-11) stability, but was labile to autoclaving. From these results, we could find a broader antifungal activity of Bacillus genus. Isolation and characterization of the active agent produced by the strain are under progress.

• Journal of Plant Biotechnology
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• 제35권1호
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• pp.13-21
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• 2008

형질전환작물 상업화의 최종 규제단계는 위해성심사와 품종출원이다. 위해성심사를 위한 형질전환작물의 위해성 평가는 광범위한 과학자 네트워크, 고비용과 오랜 기간을 필요로 한다. 따라서 형질전환작물 개발자는 우수한 형질의 개발 이외에 위해성평가에 대한 이론적 및 전략적 측면을 부가적으로 고려해야 한다. 유전자변형생물체의 위해성평가에 대한 일반적인 개념은 화학물 위해성평가로부터 유래하였다. 그러나 생물체가 가지는 복잡성 때문에 실질적동등성과 친숙성으로 대표되는 비교접근 방법이 개발되어 왔다. 실제적인 측면에서 통합적인 위해성평가는 유전자이동성, 독성과 알레르기와 같은 개별 위해성평가보다 더 어렵다. 형질전환 계통의 품종출원을 위해서는 위해성평가 단계에서부터 품종보호요건을 고려한 평가자료 생산과 위해성 심사 승인 계통을 이용한 다양한 LMO 품종 육종전략이 필요하다.

• 한국토양비료학회지
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• 제44권1호
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• pp.38-47
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• 2011

This study focused on health risk assessment via multi-routes of As exposure to establish a target cleanup level (TCL) in abandoned mines. Soil, ground water, and rice samples were collected near ten abandoned mines in November 2009. The As contaminations measured in all samples were used for determining the probabilistic health risk by Monte-Carlo simulation techniques. The human exposure to As compound was attributed to ground water ingestion. Cancer risk probability (R) via ground water and rice intake exceeded the acceptable risk range of $10^{-6}{\sim}10^{-4}$ in all selected mines. In particular, the MB mine showed the higher R value than other mines. The non-carcinogenic effects, estimated by comparing the average As exposure with corresponding reference dose were determined by hazard quotient (HQ) values, which were less than 1.0 via ground water and rice intake in SD, NS, and MB mines. This implied that the non-carcinogenic toxic effects, due to this exposure pathway had a greater possibility to occur than those in other mines. Besides, hazard index (HI) values, representing overall toxic effects by summed the HQ values were also greater than 1.0 in SD, NS, JA, and IA mines. This revealed that non-carcinogenic toxic effects were generally occurred. The As contaminants in all selected mines exceeded the TCL values for target cancer risk ($10^{-6}$) through ground water ingestion and rice intake. However, the As level in soil was greater than TCL value for target cancer risk via inadvertent soil ingestion pathway, except for KK mine. In TCL values for target hazard quotient (THQ), the As contaminants in soil did not exceed such TCL value. On the contrary, the As levels in ground water and polished rice in SD, NS, IA, and MB mines were also beyond the TCL values via ground water and rice intake. This study concluded that the health risks through ground water and rice intake were greater than those though soil inadvertent ingestion and dermal contact. In addition, it suggests that the abandoned mines to exceed the risk-based TCL values are carefully necessary to monitor for soil remediation.

• 한국산업융합학회 논문집
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• 제24권5호
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• pp.609-615
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• 2021

Chemical accidents can happen anywhere in the world. To prevent chemical accidents, Korea introduced the Chemicals Control Act. However, Small and medium-sized businesses do not meet these regulations. Accordingly, the Ministry of Environment is providing a chemical safety management support project for Small and medium-sized businesses. However, there are many small and medium-sized businesses, and businesses that need support need priority. In this study, the risk of the plants was classified into hig h, medium, and low risk based on four methods. As a result, out of 90 plants subject to the study, high risk was 30% and medium risk was 70%. The industries with the high risk were chemical products manufacturing and paint manufacturing. The plating and printing industries showed relatively medium risk. This risk classification has the advantage that it can obtain intuitive and quick results. These studies can be used as basic data for chemical safety management of local governments and Ministry of Environment.

• 한국안전학회지
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• 제10권1호
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• pp.56-63
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• 1995

Two methods of the numerical method of CPQRA(Chemical Process Quantitative Risk Analysis) and the manual method of IAEA(International Atomic Energy Agency) were used to estimate the individual risk and societal risk around the chemical plant. Where, the CPQRA is introduced to verify the theoritical background of the manual of international atomic energy agency. The Gaussian plume model which has a weather stability class D with velocity of 5m/s was applied to calculate dispersion of hazard material. Also, 8-point method was employed to the effects of accidents for wind distribution. Furthermore, historical record, FTA(Fault Tree Analysis) and ETA(Event Tree Analysis) were used to estimate the probability or frequency of accidents. Eventually, the individual risk shows isorisk contour and the societal risk shows F-N curve around hazard facility, especially in chemical plants. Caulculated results, which both individual and societal risk, by using IAEA manual show simillar results to those of calculation by numerical method of CPQRA.

• 한국가스학회지
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• 제12권2호
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• pp.25-31
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• 2008

최근 들어 도시가스사업자들이 안전관리의 수준을 더욱 향상시키기 위하여 정량적 평가(Quantitative assessment)에 기초한 위험 관리(risk management)를 많이 고려하고 있는 상황이다. 이 논문은 천연가스 배관의 정량적 위험평가의 절차에 초점을 맞췄으며, 이를 위하여 European Gas Pipeline Incident Data Group과 BG Transco의 자료를 사용한 사고발생빈도의 계산방법, 화재에 의한 사고피해영향 분석방법, 개인적 위험(Individual Risk)과 사회적 위험(Societal Risk)의 계산 방법을 체계적으로 제시하였다. 또한 국내 집단 에너지공급사업용 고압배관의 시범적용을 통하여 개인적 위험과 사회적 위험 기준을 제시하였다. 제시된 정량적 위험평가 절차는 고압배관 설계, 시공 및 변경 등의 위험관리에 유용할 것으로 판단된다.

• 한국안전학회지
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• 제8권2호
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• pp.58-63
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• 1993

Recently, a large amount of flammable or explosive materials have been handled or stored in chemical industries. H the equipments fail or the materials release in consequence of operation errors, fire and explosion could occur to them. Thus, risk assessment using quantification of risks is very important when design of processes and modifications of installed processes are performed. The purpose of this study is to develop the program for fire and explosion index in order to quantify the expected damage of fire and explosion incidents in chemical plants, to identify equipment that would be likely to contribute to the creation or escalation of an incident, to comunicate the potential fire and explosion risk to management and to account of damage cost.

• 한국가스학회지
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• 제22권3호
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• pp.84-90
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• 2018

정수장에서 염소 누출 사고 시 피해를 최소화하는 방안을 연구하였다. 장외영향평가의 위험도는 영향범위내 주민수와 사고 발생 빈도의 조합으로, 취급시설 운전온도, 긴급차단밸브 설치 위치 및 시설의 밀폐정도에 따른 피해범위 변화를 분석하여 피해범위 내 주민 수를 줄일 수 있는 최적의 조건을 제시하였다. 피해범위 산정은 KORA(Korea Off-site Risk Assessment Supporting Tool) 프로그램을 이용하였고, 운전온도가 낮아질수록, 용기의 브렌치 배관마다 긴급차단밸브가 설치될수록, 시설의 밀폐수준이 높을수록 피해범위가 감소하였다. 최악의 사고시나리오에서 감소율은 각각 17.6%, 71%, 34.5% 이며, 대안의 사고시나리오에는 각각 31.6%, 69.0%, 34.8% 이다.

• 한국안전학회지
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• 제33권5호
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• pp.141-149
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• 2018

In a PCB factory, there is a corrosive chemical substance supply system that can causes major leakage accidents. These accidents can give rise to shut down the factory and do residents damage that cause enormous loss of properties. To mitigate these risks, it is necessary to provide a chemical disaster prevention system. Moreover, after considering the situation and environment of the production site, it is of great importance to build an optimal chemical accident prevention system by reflecting risk reduction measures from the point of process design and by assessing quantitative risk based on reliability data. However, because there was no established database of the reliability about facilities and equipment that can be used in the domestic, the business site and consulting organization had being used the reliability data such as USA CCPS(Center for Chemical Process Safety). In these days, Korean institutes are studying on reliability data utilization method of quantitative risk assessment for preventing chemical accidents and domestic utilization algorithms and storage bed of reliability data. This study presents samples of reliability database about the chemical substance supply system that constructed from the history data such as failure, maintenance for 10 years at a PCB factory. Also, this work proposes the safety design criteria for supply facilities of corrosive chemical substance by assessing quantitative risk on the basis of the reliability data.