• Asia Marketing Journal
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• v.8 no.3
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• pp.123-139
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• 2006

Cheil Communications, a leading ad agency in Korea. has been implementing successful marketing strategies in the following three areas: (1) total strategic planning that maximizes clients' brand equity; (2) distinctive creative strategies that increase viewer acceptance with outstanding artwork; and (3) media planning and execution strategies based on systematic consumer research. This case demonstrates how Cheil Communications has empowered the clients' brands in the ever-changing marketplace, reinventing itself as a prominent global agency for the future.

• Clinical and Experimental Reproductive Medicine
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• v.39 no.1
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• pp.10-14
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• 2012

The ovarian follicles develop initially from primordial follicles. The majority of ovarian primordial follicles are maintained quiescently as a reserve for the reproductive life span. Only a few of them are activated and develop to an advanced follicular stage. The maintenance of dormancy and activation of primordial follicles are controlled by coordinated actions of a suppressor/activator with close communications with somatic cells and intra-oocyte signaling pathways. Many growth factors and signaling pathways have been identified and the transforming growth factor-beta superfamily plays important roles in early folliculogenesis. However, the mechanism of maintaining the dormancy and survival of primordial follicles has remained unknown for decades. Recently, since the first finding that all primordial follicles are activated prematurely in mice deficient forkhead box O3a, phosphatidylinositol 3 kinase/phosphatase and tensin homolog (PTEN) signaling pathway was reported to be important in the regulation of dormancy and initial follicular activation. With these informations on early folliculogenesis, clinical application can be expected such as in vitro maturation of immature oocytes or in vitro activation of follicles by PTEN inhibitor in cryopreserved ovarian cortical tissues for fertility preservation.