• Title/Summary/Keyword: Charles Darwin

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Trends in Incidence of Head and Neck Cancer in the Northern Territory, Australia, between 2007 and 2010

  • Jayaraj, Rama;Singh, Jagtar;Baxi, Siddhartha;Ramamoorthi, Ramya;Thomas, Mahiban
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7753-7756
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    • 2014
  • Incidence trends of head and neck cancer (HNC) have implications for screening strategies, disease management, guiding health policy making, and are needed to further oral cancer research. This paper aims to describe trends in age-adjusted HNC incidence rates focusing on changes across calendar period between 2007 and 2010 in Australian Northern Territory. Age-adjusted incidence rates of HNC were calculated for 2007-2010 using Northern Territory population based data assembled by Department of Health, Northern Territory Government of Australia. Changes in the HNC rate ratio (RR) and Estimated Annual Percentage Change (EAPC) between 2007-2008, 2008-2009 and 2009-2010 were calculated. A total of 171 HNC patients were recorded by the Northern Territory Department of Health during the time period between 2007 and 2010, out of which, 135 were males (78.9% of male HNC patients) and 36 were females (21.1% of female HNC patients). In conclusion, HNC incidence rate has decreased in the Northern Territory Australian males but remains unchanged in Australian females. High incidences of HNC may be associated with the high smoking rate and high alcohol consumption in the Northern Territory. Continued monitoring of trends in HNC incidence rates is crucial to inform Northern Territory based cancer prevention strategies.

From So Simple a Beginning, From So Simple a Theory

  • Choe, Jae-Chun
    • Journal of Ecology and Environment
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    • v.32 no.4
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    • pp.217-220
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    • 2009
  • The year of 2009 marks the $200^{th}$ anniversary of Charles Darwin's birth and the 150th anniversary of the publication of his book, On the Origin of Species. Having survived the 150 years of hardening and tempering, Darwin's theory of natural selection is now more comprehensive and powerful than ever. It casts its shadow over nearly all academic disciplines and societal sectors. It truly revolutionized the way we look at the world and ourselves. In the midst of Darwinian revolution, however, Korea remains as a backward country as far as the understanding of Darwin and his theory is concerned. A variety of intellectual activities organized to celebrate the Year of Darwin is helping to narrow the gap. This article summarizes the kinds of such activities held in Korea this year and explains how Darwin made all this possible. To paraphrase the famous quotation by Theodosius Dobzhansky, I now dare to say, "Nothing in life makes sense except in the light of evolution".

An Australian Retrospective Study to Evaluate the Prognostic Role of p53 and eIF4E Cancer Markers in Patients with Head and Neck Squamous Cell Carcinoma (HNSCC): Study Protocol

  • Singh, Jagtar;Jayaraj, Rama;Baxi, Siddhartha;Mileva, Mariana;Curtin, Justin;Thomas, Mahiban
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4717-4721
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    • 2013
  • Complete surgical resection of the primary tumour is a crucial predictive step for head and neck squamous cell carcinoma (HNSCC), because incomplete resection may lead to increase in the recurrence rate. Molecular cancer markers have been investigated as potential predictors of prognosis marker, to identify patients who are at high risk of local recurrence. This retrospective study aimed to determine the prognostic correlation between p53 and eIF4E expression and clinical characteristics, recurrence and overall survival. Forty eight HNSCC patients were selected between 2006 and 2009 diagnosed at the Royal Darwin Hospital, Darwin, Northern Territory, Australia. Out of 48, only those 24 with negative surgical margins with hematoxylin and eosin (HandE) were chosedn for further analysis. A total of 77 surgical margins were obtained and subsequently analysed by immunohistochemical (IHC) staining with monoclonal p53 and polyclonal eIF4E antibodies. Contingency table and ${\chi}^2$-test were used to investigate the correlation between p53 and eIF4E expression and clinical characteristics, recurrence and overall survival of the HNSCC patients. The follow up period was 74 months (range 1-74 months). The Kaplan-Meier method was used to generate recurrence and survival curves. This is a first retrospective study of Northern Territory patients, including Indigenous and non-Indigenous Australians. Molecular study of surgical margins could help to identify patients with and without clear margins after surgery and help in choice of the most appropriate adjuvant treatment for HNSCC patients.

Charles Darwin's 'The Voyage of the Beagle (찰스 다윈의 '비글호 항해기'와 지구과학)

  • Chang, Soon-Keun
    • Journal of the Korean earth science society
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    • v.21 no.4
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    • pp.488-501
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    • 2000
  • 'The Voyage of the Beagle' , one of the best record of scientific travels ever made, written by Charles Darwin (1809-82), the greatest naturalist ever born, is reviewed in the viewpoint of the Earth Sciences. Various observations and interpretations on the Earth Sciences are told in the Voyage. First of all, Darwin understood the geological time much more longer than accepted then as well as the geological phenomena and processes such as orogeny, uplifting, subsidence, erosion, and deposition. And he also provided a perfect interpretation on the formation of coral reefs and a good theory on the evolution of organisms. Reasonable paleoenvironmental reconstructions and interpretations based on the fossils were given in the Voyage. His observations on meteorological phenomena were from the dust composed of organisms collected on the 'Beagle' in the Atlantic Ocean, to the movement of air and extreme clear dry condition experienced on the crest of the Andes, and etc. He made several observations on the general oceanography such as the discoloration of the sea, the lights on the sea surface, conchoidal provinces noted on the Galapagos Archipelago, the trees and plants found in the remotely separated islands, and etc. However relatively scarce observation was carried out on astronomy probably due to his relatively much land travelling. Most of his interpretations and suggestions are accepted in this time.

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Post-traumatic Stress Disorder and Post-traumatic Growth in Breast Cancer Patients - a Systematic Review

  • Parikh, Darshit;Ieso, Paolo De;Garvey, Gail;Thachil, Thanuja;Ramamoorthi, Ramya;Penniment, Michael;Jayaraj, Rama
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.641-646
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    • 2015
  • Breast cancer (BC) is potentially a traumatic stressor which may be associated with negative outcomes, such as post-traumatic stress disorder (PTSD) or positive changes, such as post-traumatic growth (PTG). This study aims to identify the core issues of BC related PTSD, PTG and psychological distress by interrogating the literature in BC survivors. We have also highlighted issues related to the assessment, diagnosis and clinical management of PTSD and PTG. The authors systematically reviewed studies published from 1985 to 2014 pertaining to PTSD, psychological distress and PTG in BC survivors with particular attention paid to incidence rates and causative factors. Multiple studies intimated that women with BC have evidence of PTSD at the initial stages of diagnosis, whereas PTG develops once patients undergo treatment. Early diagnosis and treatment of PTSD/PTG is paramount from literature review but the previously mentioned relationship between PTSD and PTG in BC patients could not be verified. It is evident from the literature that a small percentage of BC patients experience PTSD, while the majority experience PTG after BC diagnosis and treatment. Future research should include prospective studies focusing on high-risk patients, causative factors and the development of psychological interventions.

Incidence and Mortality from Mucosal Head and Neck Cancers amongst Australian States and Territories: What It Means for the Northern Territory

  • Singh, Jagtar;Jayaraj, Rama;Baxi, Siddhartha;Ramamoorthi, Ramya;Thomas, Mahiban
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5621-5624
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    • 2013
  • Mucosal head and neck cancers are squamous cell carcinomas that develop in the upper-aero digestive epithelium. Together they constitute the sixth most common cancer with an estimated 900,000 new cases and 350,000 deaths each year reported worldwide. The risk factors are tobacco, alcohol and human papillomavirus (HPV). Our research team initially reported a high incidence rate of HNC in the indigenous population of the Northern Territory. Mortality rates also vary in the Australian States and Territories, with particularly high mortality observed in the Northern Territory. There is a paucity of incidence studies of HNC for the Australian States and Territories. Therefore this review primarily focuses on variation in incidence and mortality iacross the country and highlights specifically the high incidence and mortality in the Northern Territory. Attention is also given to sex-specific incidence and mortality rates.

Brief Discussions On The Scientific Creationism Critiques (과학적 창조론 비판에 대한 소고)

  • Yang, Seung-Hun
    • Journal of The Korean Association For Science Education
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    • v.7 no.2
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    • pp.89-95
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    • 1987
  • Historically, one of the most famous and endless controversies in science and science education is on the origin of life. Since 1859, when the 1st edition of 'On The Origin Of Species' written by Charles Darwin had been published in London. evolutionism had the support of the public and scholars Creationists. however, argue recently that the scientific creationism is supported by the vast geological, biological, palaeontological biochemical and even astronomical evidences. Strong arguments of creationists stirred up the sharpening critiques of evolutionists. In this paper. the author summarizes three recent evolutionary critiques on creationism and refutes them from creationist view. After examing the critiques. we find that they are not based on the decisive evolutionary evidences but considerable conjectures And we show that the majority of critiques stem from the lack of communication in the academic communities.

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Species Diversity and Seasonal Distribution of Culicoides spp. (Diptera: Ceratopogonidae) in Jeju-do, Republic of Korea

  • Kim, Heung Chul;Bellis, Glenn A.;Kim, Myung-Soon;Klein, Terry A.;Gopurenko, David;Cai, Du-Cheng;Seo, Hyun-Ji;Cho, In-Soo;Park, Jee-Yong
    • Parasites, Hosts and Diseases
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    • v.53 no.4
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    • pp.501-506
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    • 2015
  • Biting midges belonging to the genus Culicoides (Diptera: Ceratopogonidae) were collected by Mosquito $Magnet^{(R)}$ and black light traps at 5 sites on Jeju-do, Republic of Korea (Korea), from May-November 2013 to determine species diversity and seasonal distribution. A total of 4,267 specimens were collected, of which 99.9% were female. The most common species was Culicoides tainanus (91.8%), followed by C. lungchiensis (7.2%) and C. punctatus (0.6%), while the remaining 4 species accounted for <0.5% of all Culicoides spp. that were collected. High numbers of C. tainanus were collected in May, followed by decreasing numbers through August, and then increasing numbers through November when surveillance was terminated. Peak numbers of C. lungchiensis were collected during September, with low numbers collected from May-August and October-November. The presence of C. lungchiensis in Korea was confirmed by morphological and molecular analyses.

Why Learners Found Transfer Pricing Difficult? Implications for Directors

  • Abeysekera, Indra;Jebeile, Sam
    • The Journal of Asian Finance, Economics and Business
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    • v.6 no.1
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    • pp.9-19
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    • 2019
  • A recent survey of Australian directors conducted by the Financial Reporting Council found that directors require a detailed understanding of technical accounting issues. With the aim of understanding learner difficulties in learning and applying higher learning material relevant to directors, this study explores the transfer pricing topic taught as a case presentation in an undergraduate accounting program at an Australian university. Before intervention with improvements, this study invited 25 students to take part in the study after they had learned the topic and been given one week to understand it. By adopting a transfer pricing problem presented in their essential reading and interviewing those students to gain further insights, the study found that learners experienced conceptual difficulties at various stages in attempting to learn. Intervention to ease learning difficulties was addressed through instructor training. The intervention improvements included using guided workbooks to develop a better understanding of concepts among learners, and representing the problem at hand with diagrams. After intervention with improvements, this study repeated the same procedures with 25 students who had not taken part in the previous study and found that interventions increased the learning. Results have implications for most directors, who are novices to the detailed technical accounting issues of transfer pricing.