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Synthesis and Spectroscopic Characterization of Manganese(II), Iron(III) and Cobalt(III) Complexes of Macrocyclic Ligand. Potential of Cobalt(III) Complex in Biological Activity

  • El-Tabl, Abdou S.;Shakdofa, Mohamad M.E.;El-Seidy, Ahmed M.A.
    • Journal of the Korean Chemical Society
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    • v.55 no.6
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    • pp.919-925
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    • 2011
  • A new series of manganese(II), iron(III) and cobalt(III) complexes of 14-membered macrocyclic ligand, (3,6,10,13,16,19-hexaazabicyclo[6.6.6]icosane-1,8-diamine) have been prepared and characterized by elemental analyses, IR, UV-VIS, $^1H$- and $^{13}C$- NMR spectra, magnetic susceptibilities, conductivities, and ESR measurements. Molar conductance measurements in DMF solution indicate that the complexes are electrolytes. The ESR spectrum for cobalt(III) complex in $CD_3OD+10%D_2O$ after exposure to $^{60}Co-{\gamma}$-rays at 77 K using a 0.2217 M rad $h^{-1}$ vicrad source showed $g_{\perp}$ > $g_{\parallel}$ > $g_e$, indicating that, the unpaired electron site is mainly present in the $d_z2$ orbital with covalent bond character. In this case, the ligand hyperfine tensors are nearly collinear with ${\gamma}$-tensors, so there is no major tendency to bend. Therefore, little extra delocalization via the ring lobe of the $dz^2$ orbital occurs. However, the ESR spectrum in solid state after exposure to $^{60}Co-{\gamma}$-rays at 77 K showed $g_{\parallel}$ > $g_{\perp}$ > $g_e$, indicating that, the unpaired electron site is mainly present in the $d_x2_{-y}2$ ground state as the resulting spectrum contains a large number of randomly oriented molecules provided that, the principle directions of g and A tensors. Manganese (II) complex 2, $[H_{12}LMn]Cl_4.2H_2O$, showed six isotropic lines characteristic to an unpaired electron interacting with a nucleus of spin 5/2, however, iron(III) complex 3, $[H_{12}LFe]Cl_5.H_2O$, showed spectrum of a high spin $^{57}Fe$ (I=1/2), $d^5$ configuration. The geometry of these complexes was supported by elemental analyses, IR, electronic and ESR spectral studies. Complex 1 showed exploitation in reducing the amount of electron adducts formed in DNA during irradiation with low radiation products.

Implication of policy on the evaluation and utilization of modern industrial inheritance of Daejeon (대전지역 근대산업유산의 가치와 활용에 관한 정책적 함의)

  • Choi, Jang-Nak;Lee, Sang-Hee
    • Journal of Digital Convergence
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    • v.11 no.11
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    • pp.107-115
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    • 2013
  • The Old Town of Daejeon has significantly gone down due to population decrease and vacancy of buildings. To resolve these problems, it is necessary to develop revitalization measures with unique features, but it is also important to use historical and cultural resources from a certain point for the regeneration of local community. The Old Town of Daejeon has a number of industrial structures and architectural heritages that give character to the spaces, but most of them are being impoverished without any use although they have universal value. This study examined the standards to evaluate the importance and value of modern industrial heritages as historical resources that contributed to the development of local community and discussed case studies to review the value and use of industrial heritages that laid the foundation of Daejeon's development as a modern city to address the needs for urban regeneration through preservation and use of modern industrial heritages. Also, the limitations of administrative efforts were identified and the solutions were sought to address the needs to gather efforts with local government offices and the private sector. In conclusion, this study suggests an active and open policies to use cultural heritages through the use of modern industrial heritages for the revitalization of local communities based on the study of policies for the communication of urban users and community cultural spaces, preservation of landscapes including industrial heritages, and preservation in connection to social organizations and social companies, and that it is necessary to provide policies followed by efforts, i.e., to arbitrate the owners.

Color therapy and application of color to oriental medical science (색채치료(色彩治療)와 한의학(漢醫學)에서의 색(色)의 적용(適用))

  • Park, Seung Lim;Kang, Jung Soo
    • Journal of Haehwa Medicine
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    • v.12 no.1
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    • pp.79-102
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    • 2003
  • It has been believed that the human body can be effected by color, sound, smell, and taste - each of them is based on the original character. Out of these elements, the color can be a mediation that absorbs energy into human body and adapts it to the creatures whose life are definitely based on the solar energy. This thesis makes a study of the possibility of applying the color to the oriental medical science by researching the color psychology and therapy which are studied in the west medical science, the recognition and application of color developed from orientalism, and the opinion of color in the oriental medical science. Color therapy is one of the psychological treatment techniques that are able to recover and maintain the health with the rays of the sun rays and the color. The light and the color have its energy that may relax, harmonize, encourage, or excite a human being. This is because the wavelength and the vibration of each color will take effects to human body. The core energy of absorbing and distributing the color vibration is made in the 7 "chakras" in the body, which are the pith and marrow of bio-energy directly connected with the center of the nervous system. There are several methods in the color therapy - the treatment of solar ray, the color-bath, the water-therapy using color energy, the inducement of the solar energy into the body, the acupuncture, the therapy of crystal and jewel, and the self-suggestion dependent upon the color. The color therapy can help us to keep our balance by changing the emotion into the positive energy that will cure the disease with color. As a result, this method not only must be useful to cure physical disease, or develop into good health but also will be used in conforming itself to the mental disease. The color therapy mainly uses the eight colors, which are made by mixing Red, Yellow and Blue basic colors in the field. They are never used in the treatment, but they will go along with complementary colors. This rule is closely connected with the theory of yin and yang which lies at the root of oriental philosophy, and with the treatment principle of oriental medical science whose field is focused on the balancing the body mentally as well as physically. In the East, it is the Obangsaek - the color of blue, red, yellow, white, and black in the theory of yin and yang and the five elements that have been used in helping people having trouble with their health for a long time. In the view of the oriental medical science, these five colors attached the theory of five-elements have been very useful to the physiology, the pathology, or the diagnosis, and been applied to the medical treatment, combining themselves with a five-taste in medicinal herbs. Since the study of color and human physiology has been made in some different interest and fields these days, it goes to prove that the different function of color we couldn't have got before becomes very useful to the medical science. The color must be worth researching the diversity for applying itself to the oriental medical science.

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The Population Characteristic of First Record on the Cottus koreanus from Hoam Stream, Korea (호암천에서 처음 채집된 둑중개 개체군의 특성)

  • Byeon, Hwa-Keun;Lee, Byeong-Ryong
    • Korean Journal of Environment and Ecology
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    • v.31 no.2
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    • pp.166-173
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    • 2017
  • Morphological and population characteristics of the Cottus koreanus were investigated at Hoam stream from October 2015 and April 2016. This is the first record on C. koreanus not only from Hoam stream (the upstream region of Daejong stream, Gyeongsangbuk-do Gyeongju-si Yangbuk-myeon Hoam-ri) but also from the stream flowing into the Samcheogosip stream, in the southern part of East Sea, Korea. The distribution of C. koreanus ranged from Girim temple to Yongyeon waterfall, about 1.2 km, and the water surface were about $3,600m^2$. The population size was assumed to 1,656 individual number, 46 object per $100m^2$. The morphometric characteristics of C. koreanus in the Hoam stream and the Han river are very similar except that the population at Hoam stream shorter head length, ventral fin ray length, pectoral fin ray length and mouth width when compared with the population at Han river. Other than that, the two populations showed the same meristic characters. Frequency analysis of total length indicated that the group with 40~59 mm in total length was one year old, the 60~79 mm was two years old, and the group over 80 mm was three years old. The average number of eggs in the ovaries was estimated as 361 (239~468) per matured female. The number of matured eggs size in ovaries was $2.6{\pm}0.21$ (23.~3.1) mm and this species was large eggs type. Calculation of the length-weight relation of C. koreanus showed the value of constant a as 0.00001 and b as 3.01, and the Condition factor (K) was 1.26 an on average.

A Study on Cancer Patients' Quality of Life, Perceived Health Status and Susceptibility.Severity for Cancer Recurrence (암환자의 삶의 질, 지각된 건강상태 및 암재발 인지에 관한 연구)

  • Shin, Im-Sik;Han, Sang-Sook
    • Journal of East-West Nursing Research
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    • v.11 no.2
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    • pp.146-154
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    • 2005
  • Purpose: This study was designed to identify the relationship between quality of life, perceived health status, perceived susceptibility severity to recurrence of cancer and character of object in cancer patients to provide the basic data of effective nursing interventions. Method: The subject of this study was randomly chosen from the patients diagnosed of cancer and being hospitalised or receiving chemotherapy as outpatients, at a Division of Hemato-Oncology, Department of Internal Medicine of a university hospital located in Seoul. The tool used in this study was a measurement tool for quality of life (${\alpha}=.829$), perceived health status (${\alpha}=.903$), and perceived susceptibility and severity for cancer recurrence (${\alpha}=.860$). The collected data were analysed using SPSS PC 12.0 Programme for real number, percentage, average, standard deviation, Pearson's Correlation, t-test and ANOVA, according to the purpose of this study. Result: 1) The score of quality of life in cancer patients was 3.64 point, perceived health status was 2.62 and perceived susceptibility severity to recurrence of cancer was 2.41. 2) There was a significant difference in the quality of life according to general characteristics, such as level of education, occupation, level of activity, pain, medication period, diagnosis, disease stage, purpose of medication, and recurrence. There was a significant difference in perceived health status according to age, level of activity, pain, diagnosis, purpose of medication, and recurrence. There was a significant difference in perceived susceptibility severity to recurrence of cancer according to age, level of education, and pain. 3) The cancer patients' quality of life showed significant correlation with perceived health status, perceived susceptibility severity to recurrence of cancer, pain, job, treatment purpose, relapse. The perceived health status showed significant correlation with perceived susceptibility severity to recurrence of cancer, pain, treatment purpose, relapse. The perceived susceptibility severity to recurrence of cancer showed significant correlation with pain. The relapse showed significant correlation with treatment purpose. The cancer patients' quality of life, perceived health status, and perceived susceptibility and severity for cancer recurrence, as confirmed above, showed differences according to the related factors of each subject, and it was also confirmed that those factors were significantly related with general characteristics. Upon these results, I suggest further studies on the factors that affect the cancer patients' quality of life.

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The Literal Study of Health Caring(養生)Nursing Intervention According to Sasang Constitution(四象) (사상체질별 양생 간호중재)

  • Kim, Yoon-Hee;Moon, Heui-Ja;Rho, In-Suk;Song, Young-A;Shin, Yoon-Mi;Jung, Tae-Oak
    • Journal of East-West Nursing Research
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    • v.8 no.1
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    • pp.50-62
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    • 2003
  • Through this literal study, we have endeavored to provide korea's unique nursing intervention methods based upon Lee Je-Ma's Sasang Constitutional Theory which is a unique korean medical science. The Sasang Constitution Theory lay great emphasis upon health caring medicine to promote health according to self Constitution at normal times, preventive medicine to manage byself body and mind in everyday life, and eventually, ethical medicine to love benevolence and kindness but to dislike jealousy.A variety of methods has been introduced to diagnose a person's Constitution. And yet, appearance, mind and pathological signs are three major criteria. In appearance, comprehensive features such as figure (the shape of the human body), countenance, behavior, mood, and posture are observed. In mind, nature (character), talent, steadiness, personality, and greed are investigated. In pathological signs, physiological conditions when healthy and peculiar symptoms when being ill are diagnosed. By these three criteria, each Constitution is categorised into Taiyang Person, Soyang Person, Taieum Person or Soeum Person. Different healthcaring methods exist for each Constitution such as mind and body healthcaring, diet healthcaring, knowledge and behaviour leathering, age group healthcaring, regional healthcaring, social life hralthcaring, everyday life healthcaring, and materia medication healthcaring. An independent and unique healthcaring method for each person according to self Constitution could be an important nursing intervention strategy, and can product a new nursing theory. To enjoy longevity by inducing positive caring methods, I believe that individual nursing may be the most desirable nursing approach. Lee Je-Ma's Sasang Constitution caring method is not only a general nursing theory but also expected to be an important landmark/milestone/factor in Korean nursing, preventive nursing, developing new nursing intervention methods and forming new nursing theories. Therefore, it is required to conduct thorough, practical and theoretical researches in the field of nursing.

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Neuropsychiatric Evaluation of Head-Injured Patients(I) : Comparison of Structural and Functional Brain Studies in Post-Traumatic Organic Mental Disorder (두부외상 환자의 신경정신의학적 평가(I) : 외상후 기질성정신장애 환자에서 뇌의 구조적 및 기능적 검사소견의 비교)

  • Yi, Jang Ho;Chang, Hwan-Il
    • Korean Journal of Biological Psychiatry
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    • v.3 no.1
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    • pp.57-65
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    • 1996
  • The Evaluation of patients complaining of psychiatric symptoms following head injury is much affected by the results of various tests. The objecive of this paper is to investigate the effectiveness of each lest by comparing the structual and fuctional brain studies. The subjects were 93 organic menial disorder in and out patients at the Dept. of Neuropsychiatry of the Kyung Hee University Hospital. After carrying out MRI, CT, SPECT, EEG, the results of each were analysed for the sesitivity and ability to detect focal lesion. The degree of inter-test correlations of lest results were also investigated. Furthermore, the characteristic features of psychological tests were studied and the relationship between each of above mentioned tests and psychological test was examined. As for the test sensitivity to diagnosis, the SPECT was the most superior followed by MRI, CT, EEG in thai order. In the case of abnormality, SPECT ranked 1st in detection of focal lesion, followed by MRI, CT in that order. In the inter-test result correlation, the correlation of SPECT-MRI was statistically significant. When mare than moderate abnormality EEG finding was reported, it correlated significantly with that of MRI findings. In the MMPI, the average scores on F, Hs, D, Hy, Pa, Pt, Sc subscales were above 60. Abnormal SPECT group scored significantly high on the F, Pd, Pa, Sc, Ma scales and therefore in comparison ot the SPECT normal group, displayed more psychotic features. In K-WAIS, the mean full scale IQ was down to 77. 23(Verbal IQ : 78.76, Performance IQ : 77.44) but there was no characterogic significant relationship between the lowered to and abnormal SPECT, MRI, CT and EEG results. In conclusion, 1) The SPECT was mast superior in sensitivity and detection of focal lesions. In comparision with other tests, the results of SPECT correlated well with MRI had thus is thought to be very usefull testing method in the evaluation of organic mental disorder patients. 2) The MRI had relatively high sensitivity, ability to detect focal lesion and superior correlation with other test. 3) Although EEG fared less an sensitivity in comparison to other tests, the results of above moderate abnormal grade group and that of MRI correlated significantly. 4) In the MMPI highly scored in F, Hs, D, Hy, Pa, Pt, Sc subscales and abnormal SPECT patients were shown to display more sever psychotic features. There was no significant character relationship between the lowered IQ(in K-WAIS) and abnormal findings on MRI, CT, SPECT, EEG.

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A Preliminary Study of Attentional Blink of Rapid Serial Visual Presentation in Burn Patients with Posttraumatic Stress Disorder (화상 환자에서 신속 순차 시각 제시를 이용한 주의깜빡임에 관한 예비연구)

  • Kim, Dae Hee;Jun, Bora;Seo, Cheong Hoon;Cho, Yongsuk;Yim, Haejun;Hur, Jun;Kim, Dohern;Chun, Wook;Kim, Jonghyun;Jung, Myung Hun;Choi, Ihngeun;Lee, Boung Chul
    • Korean Journal of Biological Psychiatry
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    • v.17 no.2
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    • pp.79-85
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    • 2010
  • Objectives : Trauma patients have attentional bias which enforces traumatic memories and causes cognitive errors. Understanding of such selective attention may explain many aspects of the posttraumatic stress disorder(PTSD) symptoms. Methods : We used the rapid serial visual presentation(RSVP) method to verify attentional blink in burn patients with PTSD. International affective picture system(IAPS) was used as stimuli and distracters. In the 'neutral test', patients have been presented series of pictures with human face picture as target stimuli. Each picture had 100ms interval. However the distance between target facial pictures was randomized and recognition of second facial picture accuracy was measured. In the 'stress test', the first target was stress picture which arouses patient emotions instead of the facial picture. Neutral and Stress tests were done with seven PTSD patients and 20 controls. In '85ms test' the interval was reduced to 85ms. The accuracy of recognition of second target facial picture was rated in all three tests. Eighty-five ms study was done with eighteen PTSD patients. Results : Attentional blinks were observed in 100-400ms of RSVP. PTSD patients showed increased recognition rate in the 'stress test' compared with the 'neutral test'. When presentation interval was decreased to 85 ms, PTSD patient showed decrease of attentional blink effect when target facial picture interval was 170ms. Conclusion : We found attentional blink effect could be affected by stress stimulus in burn patients. And attentional blink may be affected by stimulus interval and the character of stimulus. There may be some other specific mechanism related with selective attention in attentional blink especially with facial picture processing.

A Case Study on Social Enterprises as Social Venture in Korea (소셜 벤처로서 사회적 기업에 대한 사례연구)

  • Hwang, Sunil
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.12 no.4
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    • pp.191-200
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    • 2017
  • As Korea experienced a Asian foreign exchange crisis in 1997 and a world financial crisis in 2008, the social structure of Korea has undergone many changes. The problem of polarization has become more serious, and the social class has become harder to move between strata. This problem has been accompanied by a growing sense of crisis that the power of social development can be lost along with the problem of population cliffs. Behind the crisis is a reflection of the fact that the growth-oriented economic policies and welfare policies implemented in various European countries can not solve the problem. As an alternative to this, the emergence of social enterprises is attracting attention. Social enterprises have the characteristic of seeking to generate economic profit in order to achieve the purpose of the public interest to provide jobs to the underprivileged. In recent years, the importance of social ventures to expand the scope of new social enterprises in innovative ways has increased. The social venture is a venture business in that it takes risks to develop new areas, not existing business areas, but it also has the character of a social enterprise to achieve the public interest. In other words, an innovative corporate model that provides a creative and challenging solution of social problems in the venture spirit. Although the interest and importance of social enterprises and social ventures are increasing, this academic research is still lacking. The purpose of this study is to introduce and analyze cases of successful social enterprises and social ventures in order to reflect these social interests and their importance and to fill the gap of previous studies. In addition, I hope that this study will stimulate interest and research on the start - up of social venture.

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Genealogy of the Rainbow Stripe in Ethnic Costumes in East Asia (동부아시아 민족복식 색동계보)

  • Cho, Woo-Hyun;Kim, Mi-Jin
    • Journal of the Korean Society of Costume
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    • v.60 no.4
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    • pp.113-125
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    • 2010
  • This study is purpose to trace a genealogy of Rainbow stripe in 30 ethnic costumes in East Asia. And with through comparative views between Korean and the other minority that is shown a bilateral relation of rainbow stripe in their costume, we make sure the unique character of rainbow stripe in Korean traditional costume. The stripe in the costumes was generally used on sleeves with 3~6 patches. There were 10 types of methods for making the stripe including sewing. Weaving and sewing with trimming was also frequently used either and the stripe by weaving with multicolored yarns were mostly found in the southern region of china. Black, blue and red were frequently used in the costume as a main color that was contrasted with rainbow stripe and especially, black was mostly used. Korean preferred bright colors as a main color. Contents of the genealogy of the multicolored stripe in ethnic costume in East Asia are followed. The 28 ethnic groups who used the stripe in their dress except Korean, the Mans, Mongo people and Tibetan were located in the southern region of East Asia. And the other ethnic groups distributed in the northwest and northeast region of East Asia. The distribution of the rainbow stripe in the costume could be grouped into two sections: the southern region people and Korean-the Mongol people-the Tus- the Zangs group. And the latter group was shown strong relation with the culture of Korean's rainbow stripe costume. 11 ethnic peoples including Korean, the Vis, the Miaos, the Tus, the Mongol people, the Chaoxians, the Zangs, the Lahus, the Jinuos, the Hanis, the Luobas and the Dulongs, were saliently used the stripe in their costume. The stripe in Japanese costume was judged that was not a kind of the rainbow stripe was shown the other ethnic groups, was a color arrangement by layered dress or geometrical pattern. From above, we could recap a particular characteristic of the rainbow stripe in Korean traditional costume. Many colors were used in the stripe and bodies than the other ethnic people and the color was bright. In many cases, a color of patch at the point of armhole was red and Black color was not used in the stripe. The width of patch was a relatively narrow and regular. It has shown that the rainbow stripe in Korean traditional costume was organized independently.