• 제목/요약/키워드: Change Mechanism of Importance

검색결과 53건 처리시간 0.023초

Site | Structure | Architecture - Projects that Create Change

  • Chow, Leo;AIA, AIA;Sarkisian, Mark P.;LEED, PE SE
    • 국제초고층학회논문집
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    • 제6권3호
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    • pp.237-248
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    • 2017
  • China's rapid growth has created great opportunities for design and construction of projects that not only transform sites but cities. This work combines local, national, and international expertise in developing memorable designs that seek to humanize urban life and emphasize the importance of visionary clients. Innovative examples of work in China will be presented with emphasis on three iconic projects designed and built for Poly Corporation based in China. These projects include developments in Beijing and Guangzhou and introduce the use of locally supplied materials and construction techniques. The Poly Corporate Headquarters, the Poly Real Estate Headquarters, and the Poly International Plaza, and will be described through innovative ideas that integrate urban planning, structure, and architecture.

The Effect of the Streamlined Shoe on Dynamic Gait Change and Foot Plantar Pressure in Healthy Young Adults

  • Shim, Jae-Hun;Koong, Hwa-Soo;Chon, Seung-Chul
    • 대한인간공학회지
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    • 제32권6호
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    • pp.489-494
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    • 2013
  • Objective: This study compared the effects of streamlined shoes on dynamic gait and foot plantar pressure in healthy young adults. Background: With the importance of ankle and lower extremity mechanism, streamlined shoes are contributing to a static gait factors. However, the study of dynamic gait factor is still insufficient. Method: Sixty subjects were randomly allocated to two groups: experimental group(n=30) and control(n=30), respectively. The experimental group performed streamlined shoes, whereas the control group applied usual shoes. Main outcome measurements were assessed contact time, step length and foot plantar pressure using gait analysis with the treadmill. Independent t-test was used to compare the both groups. Results: Compared with control group, contact time of forefoot, midfoot and hindfoot decreased significantly in experimental group(p<.05), Step length increased significantly in experimental group(p<.05). Foot plantar pressure of midfoot and hindfoot increased significantly in experimental group(p<.05), whereas that of forefoot did not show significantly in experimental group(p>.05). Conclusion: Our findings suggest that streamlined shoes was more effective than usual shoes in dynamic gait change including contact time and step length and foot plantar pressure in healthy young adults. Application: The results of streamlined shoes might help to control for the gait of industrial workers.

Local Climate Mediates Spatial and Temporal Variation in Carabid Beetle Communities on Hyangnobong, Korea

  • Park, Yong Hwan;Jang, Tae Woong;Jeong, Jong Cheol;Chae, Hee Mun;Kim, Jong Kuk
    • Journal of Forest and Environmental Science
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    • 제33권3호
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    • pp.161-171
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    • 2017
  • Global environmental changes have the capacity to make dramatic alterations to floral and faunal composition, and elucidation of the mechanism is important for predicting its outcomes. Studies on global climate change have traditionally focused on statistical summaries within relatively wide scales of spatial and temporal changes, and less attention has been paid to variability in microclimates across spatial and temporal scales. Microclimate is a suite of climatic conditions measured in local areas near the earth's surface. Environmental variables in microclimatic scale can be critical for the ecology of organisms inhabiting there. Here we examine the effect of spatial and temporal changes in microclimates on those of carabid beetle communities in Hyangnobong, Korea. We found that climatic variables and the patterns of annual changes in carabid beetle communities differed among sites even within the single mountain system. Our results indicate the importance of temporal survey of communities at local scales, which is expected to reveal an additional fraction of variation in communities and underlying processes that has been overlooked in studies of global community patterns and changes.

Roles of Protein Histidine Phosphatase 1 (PHPT1) in Brown Adipocyte Differentiation

  • Kang, Joo Ae;Kang, Hyun Sup;Bae, Kwang-Hee;Lee, Sang Chul;Oh, Kyoung-Jin;Kim, Won Kon
    • Journal of Microbiology and Biotechnology
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    • 제30권2호
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    • pp.306-312
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    • 2020
  • Despite the importance of brown adipocytes as a therapeutic target for the prevention and treatment of obesity, the molecular mechanism underlying brown adipocyte differentiation is not fully understood. In particular, the role of post-translational modifications in brown adipocyte differentiation has not been extensively studied. Histidine phosphorylation is increasingly recognized an important process for protein post-translational modifications. In this study, we show that histidine phosphorylation patterns change during brown adipocyte differentiation. In addition, the expression level of protein histidine phosphatase 1 (PHPT1), a major mammalian phosphohistidine phosphatase, is reduced rapidly at the early phase of differentiation and recovers at the later phase. During white adipocyte differentiation of 3T3-L1 preadipocytes, however, the expression level of PHPT1 do not significantly change. Knockdown of PHPT1 promotes brown adipocyte differentiation, whereas ectopic expression of PHPT1 suppresses brown adipocyte differentiation. These results collectively suggest that histidine phosphorylation is closely linked to brown adipocyte differentiation and could be a therapeutic target for obesity and related metabolic diseases.

Private sector engagement in large scale solar power deployment in Sri Lanka: Role of green climate fund

  • Liyanage, Namal
    • 한국태양광발전학회지
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    • 제6권1호
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    • pp.21-34
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    • 2020
  • Sri Lanka has strongly understood the importance of mitigation of climate change and various measures have been taken. To tackle the climate change, after ratifying Paris Agreement, Sri Lanka has pledged to reduce her greenhouse gas emission in the energy sector by 20% (16% unconditional and 4% conditional) by 2030 based on the BAU scenario. Simultaneously, the government introduced its new energy policy and strategies in 2019 with a vision of achieving carbon neutrality by 2050. This paper survey related key government documents, policies, reports, and academic articles to investigate opportunities for the private sector to invest large scale solar power deployment (10 MW or above) and to get support from climate finance under article 6 of the Paris Agreement. It has found, growing concern on the environment, energy security issues and increase import expenses for fossil fuels are the main influencing factors to move renewable sources. Further, government investment and FDI both have gradually decreased in the energy sector. Therefore, an alternative financing mechanism is needed. Although the private sector allowed investing in the energy sector since 1996 with the introduction of IPP (Independent Power Producers), it could not make considerable progress on involving large scale solar utility projects. This has revealed government policy is not aligning with the long term generation plan of the electricity sector. The study has also found, it needs more strategic road map, coordination with different institutions, monitoring system to enhance large scale solar contribution.

내진성능 확보를 위한 기존교량의 보강 (Strengthening of an Existing Bridge for Achievement of Seismic Performance)

  • 국승규
    • 한국전산구조공학회논문집
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    • 제22권2호
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    • pp.181-187
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    • 2009
  • 내진 설계기준이 도입된 이후, 신설교량에 대한 내진 설계의 시행은 물론 기존교량의 내진 성능 검토에 의한 내진 성능 확보가 요구되고 있다. 기존교량의 내진 성능 확보 또한 내진 설계의 기본개념에 따라 붕괴방지수준을 만족하여야 하며, 확보방안으로는 교량의 중요도와 형식에 따라 보강규모가 다른 여러 가지 방안이 제시되어야 한다. 현재 일반교량의 경우 받침의 교체, 교각의 보강 및 전단키 설치 등의 보강방안이 내진 성능 향상 및 확보 방안으로 가장 많이 연구, 적용되고 있는 상황이다. 이 연구에서는 내진 설계가 수행되지 않은 일반적인 기존 교량은 해석대상교량으로 선정하고, 붕괴방지 수준을 만족하기 위해 연성파괴메카니즘을 확보하도록 기존교량의 설계변경을 수행하고 내진 성능을 검토하였다. 기존교량의 경우, 하부구조 교각기둥의 설계단면 결정 및 상/하부구조 연결부 받침의 기능변경 등 교량시스템의 재 설계에 의해 내진 성능을 확보할 수 있다는 것을 제시하였다.

전략적 성과측정 및 평가시스템의 개발과 적용에 관한 연구

  • 이승규;라준영;이수열
    • 한국경영과학회:학술대회논문집
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    • 한국경영과학회 1998년도 추계학술대회 논문집
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    • pp.114-117
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    • 1998
  • Failure to link business or operations strategy with the activities of operations is a critical problem in strategy implementation process. This problem comes from malfunction of a coordination and control mechanism to support the strategic direction by effective communication throughout the firm. A performance measurement and evaluation system (PMES) is thought as a core mechanism to monitor, direct. and induce desirable activities. We have developed a new strategic PMES (SPMES) that can effectively support the manufacturing strategy by utilizing customized performance measures. They are selected from a pool of four distinct but closely related sets of performance measures; financial, market, internal competency, and performance driver. In this paper, we briefly review the structure of the SPMES and explain the change process of PMES into SPMES in manufacturing business units. First we analyze the business environment and manufacturing strategy to identify short- and long-term issues facing the management. Next step is scrutinizing the objectives and activities of every function and process in the business unit. Using the information obtained, we can diagnose the gaps between currently effective PMES and desirable SPMES supporting the strategies. Once the problems in existing system are identified, we reconfigure the existing and new measures to establish a SPMES through a series of analyses, discussions and workshops. In organizing the selected measures in the new system, we use AHP method to reflect the relative importance of the measures in a specific business. Finally, modification or development of information system to support the SPMES wraps up the development process, and implementation begins. We explain the entire process using two cases to clarify the real meanings and the difficulties of PMES change process.

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REDD+ 모니터링 시스템 구축을 위한 원격탐사기술의 활용방안 (Application of Remote Sensing Technology for Developing REDD+ Monitoring Systems)

  • 박태진;이우균;정래선;김문일;권태협
    • 한국산림과학회지
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    • 제100권3호
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    • pp.315-326
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    • 2011
  • 최근 기후변화와 관련하여 국내를 비롯한 국제적인 관심이 증폭되고 있으며, 이러한 시대적인 흐름 속에 탄소흡수원으로서의 산림의 중요성이 부각되고 있다. 특히, 산림전용 및 황폐화 방지를 통한 온실가스감축(Reduced Emissions from Deforestation and Degradation, REDD) 및 산림탄소축적보존 및 증진, 지속가능한 산림경영을 포함하는 REDD+가 post-2012에 이행될 신규 메커니즘으로 활용될 전망이다. 메커니즘의 이행을 위해서는 기본적으로 MRV(Measuring, Reporting and Verification) 시스템을 통해 메커니즘 적용 효과를 인증 받아야 한다. 본 연구에서는 가장 효율적인 모니터링 방법 중 하나로 인정받고 있는 다양한 원격탐사기술의 토지피복변화 탐지 및 탄소축적량 추정하는 방법 및 효과를 비용 및 기술(불확실성)측면에서 분석하였다. 그 결과 토지피복변화탐지를 위해서는 중해상도 광학영상 및 위성 탑재 SAR(Synthetic Aperture Radar)가 가장 적합한 원격탐사자료로 도출되었다. 그리고 탄소축적량 추정에 있어서는, 항공기 탑재 LiDAR(Light Detection and Ranging), SAR와 같이 불확실성이 낮은 기술과 비용효율적인 기술인 중해상도 광학영상, 위성 탑재 SAR 간의 통합을 통해 효율적인 결과를 도출할 수 있음을 확인할 수 있었다. 하지만, 아직까지 본 메커니즘에 대한 명확한 인증기관, 가이드라인 및 불확실성에 대한 기준이 결정 되지 않고 있으므로, 추후 지속적인 관심을 통해 국제적인 흐름을 파악하고, 적합한 방법론을 구축해야 한다. 뿐만 아니라 개발된 메커니즘을 대상 개도국에 활용하기 위해서는 긴밀한 국제협력관계 구축 및 대상국에 적합한 모니터링 방법 또한 고려해야 할 필요성이 있다.

Reduced graphene oxide field-effect transistor for biomolecule detection and study of sensing mechanism

  • Kim, D.J.;Sohn, I.Y.;Kim, D.I.;Yoon, O.J.;Yang, C.W.;Lee, N.E.;Park, J.S.
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2011년도 제40회 동계학술대회 초록집
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    • pp.431-431
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    • 2011
  • Graphene, two dimensional sheet of sp2-hybridized carbon, has attracted an enormous amount of interest due to excellent electrical, chemical and mechanical properties for the application of transparent conducting films, clean energy devices, field-effect transistors, optoelectronic devices and chemical sensors. Especially, graphene is promising candidate to detect the gas molecules and biomolecules due to the large specific surface area and signal-to-noise ratios. Despite of importance to the disease diagnosis, there are a few reports to demonstrate the graphene- and rGO-FET for biological sensors and the sensing mechanism are not fully understood. Here we describe scalable and facile fabrication of rGO-FET with the capability of label-free, ultrasensitive electrical detection of a cancer biomarker, prostate specific antigen/${\alpha}1$-antichymotrypsin (PSA-ACT) complex, in which the ultrathin rGO sensing channel was simply formed by a uniform self-assembly of two-dimensional rGO nanosheets on aminated pattern generated by inkjet printing. Sensing characteristics of rGO-FET immunosensor showed the highly precise, reliable, and linear shift in the Dirac point with the analyte concentration of PSA-ACT complex and extremely low detection limit as low as 1 fg/ml. We further analyzed the charge doping mechanism, which is the change in the charge carrier in the rGO channel varying by the concentration of biomolecules. Amenability of solution-based scalable fabrication and extremely high performance may enable rGO-FET device as a versatile multiplexed diagnostic biosensor for disease biomarkers.

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미소 중력장에 있는 저신장율 화염소화에 미치는 다차원 효과 (Multi-Dimensional Effects on a tow Strain Rate Flame Extinction Under Microgravity Environment)

  • 오창보;김정수;;박정
    • 대한기계학회논문집B
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    • 제29권9호
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    • pp.988-996
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    • 2005
  • Flame structure and extinction mechanism of counterflow methane/air non-premixed flame diluted with nitrogen are studied by NASA 2.2 s drop tower experiments and two-dimensional numerical simulations with finite rate chemistry and transport properties. Extinction mechanism at low strain rate is examined through the comparison among results of microgravity experiment, 1D and 2D simulations with a finite burner diameter. A two-dimensional simulation in counterflow flame especially with a finite burner diameter is shown to be very important in explaining the importance of multidimensional effects and lateral heat loss in flame extinction, effects that cannot be understood using a one-dimensional flamelet model. Extinction mechanism at low strain rate is quite different from that at high strain rate. Low strain rate flame is extinguished initially at the outer flame edge, the flame shrinks inward, and finally is extinguished at the center. It is clarified from the overall fractional contribution by each term in energy equation to heat release rate that the contribution of radiation fraction with 1D and 2D simulations does not change so much and the overall fractional contribution is decisively attributed to radial conduction ('lateral heat loss'). The experiments by Maruta et at. can be only completely understood if multi-dimensional heat loss effects are considered. It is, as a result, verified that the turning point, which is caused only by pure radiation heat loss, has to be shifted towards much lower global strain rate in microgravity flame.