• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.9 no.2
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• pp.19-31
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• 1999

Most breakthrough tests are conducted at higher concentration levels compared to those in the field of air-purifying respirator applications. For example, typical challenge concentrations for breakthrough tests agains tcarbon tetrachloride are ranged between 250-1000 ppm although applicable concentrations range for air-purifying cartridge is 5-50 ppm for carbon tetrachloride. However, no guarantee has been made that isotherms derived from the experiment at high challenge concentrations could estimate adsorption capacity at the lower concentration range where workers wear usually air-purifying respirators. Three models of adsorption isotherms (Freundlich, Langmuir and Dubinin/Radushkevich(D/R) isotherms) that have been commonly applied for respirator cartridge testing were evaluated. Adsorption capacity at each challenge concentration was calculated from the Reaction Kinetic equation fitted for the breakthrough data. These data were used for derivation of three isotherms. In general, the D/R isotherm has given the best agreement between estimated adsorption capacities and experimentally measured. If the challenge concentration of 100 ppm is included for derivation of models, Freundlich and D/R models could succes sfully produced good estimations for adsorption capacities at 50 ppm level. Estimated adsorption capacities by both models ranged in 94 - 109 % of the experimentally measured. However, Langmuir model gives underes timation in all cases.

• Biomolecules & Therapeutics
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• v.31 no.6
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• pp.611-618
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• 2023

Rhizome of Alisma orientale has been used as a traditional medicine for treating kidney diseases in East Asian countries. Its inhibitory effects on hypersensitivity responses have been reported for methanol extracts, with alisol B 23-acetate (AB23Ac) being the most active constituent among six terpenes in inhibiting the direct passive Arthus reaction. However, whether AB23Ac has efficacy against allergic asthma has not been tested to date. The in vivo efficacy of AB23Ac in an ovalbumin (OVA)-induced allergic asthma mouse model was evaluated by administrating AB23Ac before OVA sensitization or OVA challenge in BALB/c mice. AB23Ac suppressed antigen-induced degranulation of RBL-2H3 mast cells in a concentration-dependent manner. The administration of AB23Ac both before OVA sensitization and OVA challenge greatly lowered pulmonary resistance and the increase in immune cell counts and inflammatory responses around the peribronchial and perivascular regions. In addition, the inflammatory cytokine levels of Th1/Th2/Th17 cells in the bronchoalveolar lavage fluid decreased in the AB23Ac-treated groups. AB23Ac reduced the number of PAS-stained cells in the lungs. Furthermore, a computer modeling study indicated that AB23Ac can bind tightly to spleen tyrosine kinase (Syk). These results suggest that AB23Ac may ameliorate allergic asthma by suppressing immune responses in dendritic cells during sensitization and in mast cells during challenge periods.

• International Journal of Computer Science & Network Security
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• v.23 no.12
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• pp.81-90
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• 2023

Cloud computing is an emerging business model popularized during the last few years by the IT industry. Providing "Everything as a Service" has shifted many organizations to choose cloud-based services. However, some companies still fear shifting their data to the cloud due to issues related to the security and privacy. The paper suggests a novel Trust based Mutual Authentication Mechanism using Secret P-box based Mutual Authentication Mechanism (TbMAM-SPb) on the criticality of information. It uses a particular passcodes from one of the secret P-box to act as challenge to one party. The response is another passcode from other P-box. The mechanism is designed in a way that the response given by a party to a challenge is itself a new challenge for the other party. Access to data is provided after ensuring certain number of correct challenge-responses. The complexity can be dynamically updated on basis of criticality of the information and trust factor between the two parties. The communication is encrypted and time-stamped to avoid interceptions and reuse. Overall, it is good authentication mechanism without the use of expensive devices and participation of a trusted third party.

• The Journal of the Korea Contents Association
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• v.11 no.5
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• pp.291-301
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• 2011

This research describes the comparison broker's role and its effectiveness measurement framework of comparison shopping. We verified seller-led comparison challenge method provide comparison information of products to buyers more efficiently. Buyer's satisfaction of purchase (S) can be defined as an interactive function between seller's competitiveness vector (P) of products that supplied to the market, and buyer's informed level vector (B) of products that is known from a lot of sources. Then the buyer's informed level can be changed through the information analysis among products by transformation process using comparison matrix (C). So the role of comparison shopping is to construct a comparison matrix and to serve it to the buyers, and to change the buyer's informed level. The changed informed level influences a buyer's satisfaction, that improved satisfaction of purchase is defined as the effectiveness of comparison shopping. As a perfect construction and usage of comparison matrix is impossible, a more efficient method for improving the comparison effectiveness is the comparison challenge. This research shows that comparison shopping makes 9.32% and comparison challenge makes 19.11% enhancement of comparison effectiveness through television market data experiments.

• The Journal of the Acoustical Society of Korea
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• v.40 no.5
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• pp.479-487
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• 2021

In this paper, we propose an Sound Event Detection (SED) model using self-training based on a noisy student model. The proposed SED model consists of two stages. In the first stage, a mean-teacher model based on an Residual Convolutional Recurrent Neural Network (RCRNN) is constructed to provide target labels regarding weakly labeled or unlabeled data. In the second stage, a self-training-based noisy student model is constructed by applying different noise types. That is, feature noises, such as time-frequency shift, mixup, SpecAugment, and dropout-based model noise are used here. In addition, a semi-supervised loss function is applied to train the noisy student model, which acts as label noise injection. The performance of the proposed SED model is evaluated on the validation set of the Detection and Classification of Acoustic Scenes and Events (DCASE) 2020 Challenge Task 4. The experiments show that the single model and ensemble model of the proposed SED based on the noisy student model improve F1-score by 4.6 % and 3.4 % compared to the top-ranked model in DCASE 2020 challenge Task 4, respectively.

• Proceeding of EDISON Challenge
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• 2016.03a
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• pp.344-346
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• 2016

본 논문에서는 3-stream model에 기반한 Dopant diffusion simulator를 사용하여 실리콘 기판 내부의 As이온의 확산을 시뮬레이션한 결과와 Dual-Pearson Analytic model에 기반하여 Ion implantation을 1-D doping simulation한 결과를 토대로 여러 공정 설계에서 diffusion simulator의 사용가능함을 확인하였다.

• Korean Journal of Social Welfare
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• v.67 no.2
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• pp.203-236
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• 2015

Given the interdependence of a marital couple, this study examined the effects of both cultural challenge and economic hardship on intention to divorce among the multicultural couple using the actor-partner interdependence model(APIM), and explored dyadic patterns of actor and partner effects. 415 couples(n=830) participated in this self-administered questionnaire study. Results of path analyses based on APIMs revealed that for Korean husbands perceived cultural challenge contributed positively to divorce intention of the couple showing both actor and partner effects, whereas for immigrant wives such perception showed only an actor effect. In contrast, perceived economic hardship among the husbands had little effect on divorce intention of both husbands and wives, whereas such perception by wives had both actor and partner effects on divorce intention. Results of dyadic pattern analyses performed by Bootstrap indicated the actor-only pattern and the couple pattern of perceived cultural challenge on divorce intention of husbands and wives respectively. In case of perceived economic hardship comparison of the effect size suggested the partner-only pattern and the actor-only pattern for divorce intention of husbands and wives respectively. These findings implied that in order to promote conjugal harmony and to prevent the multicultural family from being dissolved, Korean husbands need to develop greater cultural competence so as to tolerate cultural differences between the couple, whereas immigrant wives and their families need to develop greater economic competence so as to foster a hope for economic reliance.

• Journal of the Korean Data and Information Science Society
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• v.26 no.2
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• pp.495-504
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• 2015

The Gaussian geostatistical model has been widely used for modeling spatial data. However, this model suffers from a severe difficulty in computation because inference requires to invert a large covariance matrix in evaluating log-likelihood. In addressing this computational challenge, three strategies have been employed: likelihood approximation, lower dimensional space approximation, and Markov random field approximation. In this paper, we reviewed statistical approaches attacking the computational challenge. As an illustration, we also applied integrated nested Laplace approximation (INLA) technology, one of Markov approximation approach, to real data to provide an example of its use in practice dealing with large spatial data.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.10a
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• pp.441-443
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• 2018

This paper deals with the analysis of leg motion using RGB image. We used RGB image as gait analysis element by using BMC(Background Model Challenge) method and by using combining object recognition segmentation algorithm and attitude detection algorithm. It is considered that gait analysis incorporating image can be used as a parameter for classification of gait pattern recognition and abnormal gait.

• Biotechnology and Bioprocess Engineering:BBE
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• v.9 no.6
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• pp.490-494
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• 2004

An efficacy test of PRP (polyribosylribitol phosphate)-TT (Tetanus toxoid) conjugate vaccines was carried out using BALB/c mice as an animal model by inoculating Haemophilus in­fluenzae type b (Hib) with a virulence enhancement factor (VEF). Three administrations of the conjugate vaccines at 2-week intervals elicited a significantly high level of PRP antibodies (P>0.0001). The protective activity of the PRP immunization was challenged with either Hib with iron dextran (Hib/) or with a combination of mucin and hemoglobin (Hibmh) as a VEF. The me­dium lethal dose $(LD_{50})$ for Hibmh and Hibiwas measured as 10 CFU (Colony Forming Unit) and $2.5{\times}10^{8}$ CFU respectively. Each immunized animal was challenged with five or ten times the $LD_{50}$ level of bacteria with a VEF. A significant difference in mortality between the immunized and control mice (P> 0.01) was observed with the Hibmh challenge inoculation but not with the Hibi challenge inoculation. These results show that a combination of mucin and hemoglobin was able to enhance the virulence of Hib in BALB/c mice to cause a lethal infection, thus suggesting that BALB/c mice introduced to this method can be an effective model animal for testing the protective efficacy of H. influenzae conjugate vaccines.