• BMB Reports
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• v.54 no.6
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• pp.329-334
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• 2021

Collagen type I is the most abundant form of collagen in human tissues, and is composed of two identical α-1 type I chains and an α-2 type I chain organized in a triple helical structure. A previous study has shown that human collagen α-2 type I (hCOL1A2) promotes collagen synthesis, wound healing, and elastin production in normal human dermal fibroblasts (HDFs). However, the biological effects of human collagen α-1 type I (hCOL1A1) on various skin properties have not been investigated. Here, we isolate and identify the hCOL1A1-collagen effective domain (CED) which promotes collagen type I synthesis. Recombinant hCOL1A1-CED effectively induces cell proliferation and collagen biosynthesis in HDFs, as well as increased cell migration and elastin production. Based on these results, hCOL1A1-CED may be explored further for its potential use as a preventative agent against skin aging.

• Applied Chemistry for Engineering
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• v.33 no.3
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• pp.322-327
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• 2022

Fucoidans were degraded by hydrogen peroxide under the electron beam (2.5 MeV) with various radiation doses (5 kGy, 10 kGy, 15 kGy, and 20 kGy) at room temperature. The degradation property was analyzed with a gel permeation chromatography (GPC-MALLS) method. An average molecular weight of fucoidan decreased from 99,956 at the irradiation dose of 0 kGy to 6,725 at the irradiation dose of 20 kGy. The solution viscosity of fucoidans showed a similar pattern to the molecular weight change. The number of chain breaks per molecule (N) increased with increasing the irradiation dose and concentration of hydrogen peroxide. The radiation yield of scission value markedly increased with increasing the irradiation dose up to 15 kGy. Also a 10% hydrogen peroxide concentration was more efficient than that of 5%. The structures of degraded fucoidan samples were studied with Fourier transform infrared spectroscopy (FT-IR). The results showed that the degradation process did not significantly change the chemical structure or the content of sulfate group. The sulfur content of each sample was determined with an Elemental Analyzer. With increasing the concentration of hydrogen peroxide, the ratios of sulfur/carbon, hydrogen/carbon, and nitrogen/carbon slightly decreased. The antioxidant activities of fucoidans were investigated based on hydroxyl radical scavenging activities. The ability of fucoidan to inhibit the hydroxyl radical scavenging activity was depended on its molecular weight.

• Development and Reproduction
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• v.24 no.4
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• pp.327-335
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• 2020

Genomic DNA (gDNA) extracted from two populations of natural and cultured river pufferfish (Takifugu obscurus) was amplified by polymerase chain reaction (PCR). The complexity of the fragments derived from the two locations varied dramatically. The genetic distances (GDs) between individuals numbered 15 and 12 in the cultured population was 0.053, which was the lowest acknowledged. The oligonucleotide primer OPC-11 identified 88 unique loci shared within each population reflecting the natural population. The OPC-05 primer identified 44 loci shared by the two populations. The average band-sharing (BS) values of individuals in the natural population (0.683±0.014) were lower than in those derived from the cultured population (0.759±0.009) (p<0.05). The shortest GD demonstrating a significant molecular difference was found between the cultured individuals # 15 and # 12 (GD=0.053). Individual # 02 of the natural population was most distantly related to cultured individual # 22 (GD=0.827). A cluster tree was built using the unweighted pair group method with arithmetic mean (UPGMA) Euclidean GD analysis based on a total of 578 various fragments derived from five primers in the two populations. Obvious markers identified in this study represent the genetic structure, species security, and proliferation of river pufferfish in the rivers of the Korean peninsula.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.2
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• pp.75.4-75.4
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• 2019

We present a quantitative analysis of the relationship between the gas dynamics and star formation history of DDO 210 which is an irregular dwarf galaxy in the local Universe. We perform profile analysis of an high-resolution neutral hydrogen (HI) data cube of the galaxy taken with the large Very Large Array (VLA) survey, LITTLE THINGS using newly developed algorithm based on a Bayesian Markov Chain Monte Carlo (MCMC) technique. The complex HI structure and kinematics of the galaxy are decomposed into multiple kinematic components in a quantitative way like 1) bulk motions which are most likely to follow the underlying circular rotation of the disk, 2) non-circular motions deviating from the bulk motions, and 3) kinematically cold and warm components with narrower and wider velocity dispersion. The decomposed kinematic components are then spatially correlated with the distribution of stellar populations obtained from the color-magnitude diagram (CMD) fitting method. The cold and warm gas components show negative and positive correlations between their velocity dispersions and the surface star formation rates of the populations with ages of < 40 Myr and 100~400 Myr, respectively. The cold gas is most likely to be associated with the young stellar populations. Then the stellar feedback of the young populations could influence the warm gas. The age difference between the populations which show the correlations indicates the time delay of the stellar feedback.

• Structural Engineering and Mechanics
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• v.87 no.1
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• pp.1-18
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• 2023

The paper presents a Bayesian Finite element (FE) model updating methodology by utilizing modal data. The dynamic condensation technique is adopted in this work to reduce the full system model to a smaller model version such that the degrees of freedom (DOFs) in the reduced model correspond to the observed DOFs, which facilitates the model updating procedure without any mode-matching. The present work considers both the MPV and the covariance matrix of the modal parameters as the modal data. Besides, the modal data identified from multiple setups is considered for the model updating procedure, keeping in view of the realistic scenario of inability of limited number of sensors to measure the response of all the interested DOFs of a large structure. A relationship is established between the modal data and structural parameters based on the eigensystem equation through the introduction of additional uncertain parameters in the form of modal frequencies and partial mode shapes. A novel sampling strategy known as the Metropolis-within-Gibbs (MWG) sampler is proposed to sample from the posterior Probability Density Function (PDF). The effectiveness of the proposed approach is demonstrated by considering both simulated and experimental examples.

• Smart Structures and Systems
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• v.31 no.1
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• pp.29-43
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• 2023

This study investigates the possibility of damage detection of a real bridge by means of a modal parameter-based finite element (FE) model update. Field moving vehicle experiments were conducted on an actual steel plate girder bridge. In the damage experiment, cracks were applied to the bridge to simulate damage states. A fast Bayesian FFT method was employed to identify and quantify uncertainties of the modal parameters then these modal parameters were used in the Bayesian model update. Material properties and boundary conditions are taken as uncertainties and updated in the model update process. Observations showed that although some differences existed in the results obtained from different model classes, the discrepancy between modal parameters of the FE model and those experimentally obtained was reduced after the model update process, and the updated parameters in the numerical model were indeed affected by the damage. The importance of boundary conditions in the model updating process is also observed. The capability of the MCMC model update method for application to the actual bridge structure is assessed, and the limitation of FE model update in damage detection of bridges using only modal parameters is observed.

• Korea Trade Review
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• v.46 no.1
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• pp.59-81
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• 2021

This paper aims to analyze Korea's trade and investment performance in Spain and the business environment of Spain, and to find efficient strategies for entering into the Spanish market. This study is organized into five chapters. To begin with, it explains an overview of the Spanish economy and the current status of its major industries. Then, it analyzes Korea's trade and investment performance in Spain, the structure of comparative advantage and the trade trends of major import and export items, since 2011 when the Korea-EU FTA went into effect. Lastly, based on the results of this analysis, Korea's strategies for entering into the Spanish market are derived. The strategies derived from the analysis are as follows: (1) entering startups in the Spanish market through CVC cooperation and participation in large tech forums, (2) linking the Spanish interest in K-Culture to consumer goods exports, (3) promoting cooperation in the IT industry in response to the Spanish government's 'Connected Industry 4.0', (4) building a new Korean-Spanish value chain in response to the mobility revolution, (5) advancing jointly into a third country by combining the strengths of both Korea and Spain, (6) cooperating with the Spanish government to establish a sustainable energy policy, (7) promoting jointly with the Spanish government through smart city strategies and project exchanges, and (8) building a European logistics hub in Spain in preparation for post-Brexit.

• Journal of the Korean Society of Clothing and Textiles
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• v.47 no.6
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• pp.977-995
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• 2023

This study was aimed at determining the connection between ancient Korean embroidery and the Cheonsuguk mandala-embroidery insignia. Literature and empirical studies were conducted simultaneously, with the scope of these analyses spanning up to 7C in ancient Korea and Japan. The present study confirmed that the structure of Goguryeo tomb murals influenced by Buddhist art is represented in the Cheonsuguk mandala-embroidery insignia, and changes in the image resulted in modifications to the embroidery technique. Embroidery and color composition via complementary color contrast were implemented through Variant 1 outline stitching, which exhibited the development of Baekje embroidery. The embroidery technique confirmed that the form of embroidery developed in to chain stitching, needle looping stitching, outline stitching, satin stitching and Variant 1·2 outline stitching. These findings indicate that Cheonsuguk mandala-embroidery insignia is the result of the integration of the Goguryeo and Baekje cultures.

• Nuclear Engineering and Technology
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• v.56 no.2
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• pp.498-505
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• 2024

In this paper, a cable-driven endoscopic manipulator (CEM) is designed for the Chinese latest compact fusion reactor. The whole CEM arm is more than 3000 mm long and includes end vision tools, an endoscopic manipulator/control system, a feeding system, a drag chain system, support systems, a neutron shield door, etc. It can cover a range of ±45° of the vacuum chamber by working in a wrap-around mode, etc., to meet the need for observation at any position and angle. By placing all drive motors in the end drive box via a cable drive, cooling, and radiation protection of the entire robot can be facilitated. To address the CEM motion control problem, a discrete trajectory tracking method is proposed. By restricting each joint of the CEM to the target curve through segmental fitting, the trajectory tracking control is completed. To avoid the joint rotation angle overrun, a joint limit rotation angle optimization method is proposed based on the equivalent rod length principle. Finally, the CEM simulation system is established. The rationality of the structure design and the effectiveness of the motion control algorithm are verified by the simulation.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.7
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• pp.2047-2066
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• 2024

In order to improve the coverage and achieve massive spectrum access, non-orthogonal multiple access (NOMA) technology is applied in millimeter wave massive multiple-input multiple-output (mMIMO) communication network. However, the power assumption of active sensors greatly limits its wide applications. Recently, Intelligent Reconfigurable Surface (IRS) technology has received wide attention due to its ability to reduce power consumption and achieve passive transmission. In this paper, spectral efficiency maximum problem in the millimeter wave mMIMO-NOMA system with IRS is considered. The sparse RF chain antenna structure is designed at the base station based on continuous phase modulation. Furthermore, a joint optimization problem for power allocation, power splitting, analog precoding and IRS reconfigurable matrices are constructed, which aim to achieve the maximum spectral efficiency of the system under the constraints of user's quality of service, minimum energy harvesting and total transmit power. A three-stage iterative algorithm is proposed to solve the above mentioned non-convex optimization problems. We obtain the local optimal solution by fixing some optimization parameters firstly, then introduce the relaxation variables to realize the global optimal solution. Simulation results show that the spectral efficiency of the proposed scheme is superior compared to the conventional system with phase shifter modulation. It is also demonstrated that IRS can effectively assist mmWave communication and improve the system spectral efficiency.