• Title/Summary/Keyword: Cfo1

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A Ferroxidase, Cfo1, Regulates Diverse Environmental Stress Responses of Cryptococcus neoformans through the HOG Pathway

  • Lee, Kyung-Tae;Lee, Jang-Won;Lee, Dohyun;Jung, Won-Hee;Bahn, Yong-Sun
    • Mycobiology
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    • v.42 no.2
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    • pp.152-157
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    • 2014
  • The iron uptake and utilization pathways play a critical role in allowing human pathogens, including Cryptococcus neoformans, the causative agent of fatal meningoencephalitis, to survive within the mammalian body by competing with the host for iron. Here we show that the iron regulon is also required for diverse environmental stress responses and that in C. neoformans, it is regulated by the high-osmolarity glycerol response (HOG) pathway. Between CFO1 and CFO2, two ferroxidase genes in the iron regulon, CFO1 but not CFO2 was induced during oxidative and osmotic stress. Interestingly, we found that the HOG pathway repressed basal expression of both CFO1 and CFO2. Furthermore, when the HOG pathway was blocked, CFO2 also responded to oxidative and osmotic stress and the response of CFO1 was increased. We also established that CFO1 plays a major role in responding and adapting to diverse environmental stresses, including oxidative and genotoxic damage, osmotic fluctuations, heavy metal stress, and stress induced by cell membrane destabilizers. Therefore, our findings indicate that in C. neoformans, the iron uptake and utilization pathways are not only required for iron acquisition and survival, but also play a significant role in the environmental stress response through crosstalk with the HOG pathway.

3D Hierarchical Flower-Like Cobalt Ferrite Nanoclusters-Decorated Cotton Carbon Fiber anode with Improved Lithium Storage Performance

  • Meng, Yanshuang;Cheng, Yulong;Ke, Xinyou;Ren, Guofeng;Zhu, Fuliang
    • Journal of Electrochemical Science and Technology
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    • v.12 no.2
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    • pp.285-295
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    • 2021
  • The inverse spinel Cobalt ferrite (CoFe2O4, CFO) is considered to be a promising alternative to commercial graphite anodes for lithium ion batteries (LIBs). However, the further development of CFO is limited by its unstable structure during battery cycling and low electrical conductivity. In an effort to address the challenge, we construct three-dimensional hierarchical flower-like CFO nanoclusters (CFO NCs)-decorated carbonized cotton carbon fiber (CFO NCs/CCF) composite. This structure is consisted of microfibers and nanoflower cluster composited of CFO nanoparticle, in which CCF can be used as a long-range conductive matrix, while flower-like CFO NCs can provide abundant active sites, large electrode/electrolyte interface, short lithium ion diffusion path, and alleviated structural stress. As anode materials in LIBs, the flower-like CFO NCs/CCF exhibits excellent electrochemical performance. After 100 cycles at a current density of 0.3 A g-1, the CFO NCs/CCF delivers a discharge/charge capacity of 1008/990 mAh g-1. Even at a high current density of 15 A g-1, it still maintains a charge/discharge capacity of 362/361 mAh g-1.

Magnetocapacitance Properties of Multilayered CoFe2O4/BaTiO3/CoFe2O4 Thin Film by Pulsed Laser Deposition

  • Lee, Seong Noh;Shim, Hyun Ju;Shim, In-Bo
    • Journal of Magnetics
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    • v.19 no.2
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    • pp.121-125
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    • 2014
  • $CoFe_2O_4(CFO)/BaTiO_3(BTO)/CoFe_2O_4(CFO)$ multilayered thin films were deposited on $Pt/TiO_2/SiO_2/Si$ substrates by the pulsed laser deposition (PLD) system with KrF excimer laser (${\lambda}=248nm$). BTO, CFO, BTO/CFO and CFO/BTO/CFO structured thin films were prepared and their crystal structures and microstructures, as well as their magnetic and magneto-electrical properties, were studied. The C-V characteristics of these multilayered thin films with different capacitor structures were obtained to confirm the change in their capacitances under a magnetic field. Finally, the capacitance of the CFO/BTO/CFO thin film as a function of bias voltage under an in-plane magnetic field of 1,000 Oe increased to 951.04 pF at 1 MHz, from 831.90 pF measured under no magnetic field, indicating 14.3% increase in magnetocapacitance.

An Enhanced Scheme with CFO and SFO in OFDMA system (OFDMA 시스템에서 SFO와 CFO 저감 기법에 관한 연구)

  • Lee, Young-Gwang;Lee, Kyu-Seop;Choi, Gin-Kyu
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.14 no.1
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    • pp.1-6
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    • 2014
  • Recently, orthogonal frequency-division multiplexing(OFDM), with clusters of subcarriers allocated to different subscribers(often referred to as OFDMA), has gained much attention for its ability in enabling multiple-access wireless multimedia communications. In such systems, carrier frequency offsets (CFOs) can destroy the orthogonality among subcarriers. And the mismatch in sampling frequencies between transmitter and receiver can lead to serious degradation due to the loss of orthogonality between the subcarriers. As a result, multiuser interference (MUI) along with significant performance degradation can be induced. In this paper, we present a scheme to compensate for the SFOs and CFOs at the base station of an OFDMA system. A novel sampling frequency offset estimation algorithm is proposed, which is based on the repetition of a symbol at the communication start-up. Then, circular convolutions are employed to generate the interference after the discrete Fourier transform processing, which is then removed from the original received signal to increase the signal to interference power ratio(SIR). Simulation result shows that the proposed scheme can improve system performance.

Robust CFO Acquisition in PN-Padded OFDM Systems

  • Liu, Guanghui;Zeng, Liaoyuan;Li, Hongliang;Xu, Linfeng;Wang, Zhengning
    • ETRI Journal
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    • v.35 no.4
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    • pp.706-709
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    • 2013
  • As an alternative to the traditional pilot-aided orthogonal frequency division multiplexing (OFDM), the time-domain pseudonoise (PN)-padded OFDM provides a higher spectral efficiency. However, the carrier frequency offset (CFO) attenuates peaks of the conventional PN correlation output, which limits the CFO estimation range of the OFDM synchronizer. An improved correlation is proposed in this letter to remove the CFO-induced amplitude attenuation of correlation peaks. For a synchronizer adopting the designed correlator, a larger range of CFO acquisition is obtained through using wider correlation windows with a smaller interval between them. The proposed method of CFO acquisition is verified in a digital terrestrial multimedia broadcast receiver, in which the synchronizer is able to acquire CFOs up to ${\pm}320$ kHz in the DVB-T F1 channel. Furthermore, the acquisition range can be expanded in more favorable channels.

An Optimized Multi-Bit Digital FSK Receiver Robust to CFO for Long-Range WPAN Applications (광역 WPAN 응용을 위한 주파수 오차에 강인한 최적 다중비트 디지털 FSK 수신기)

  • Oh, Mi-Kyung;Choi, Sangsung
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39A no.1
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    • pp.43-49
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    • 2014
  • This paper proposes an optimized multi-bit digital FSK receiver robust to large carrier frequency offset (CFO) toward recently emerging long-range WPAN standards. Due to a short preamble length and strict BER requirements, we design a simple multi-bit digital demodulator combined with CFO estimator which guarantees the target BER performance. Simulation results verify that the proposed FSK receiver achieves CFO-free BER performance with the short preamble and satisfies the BER requirement by the recent WPAN applications.

Carrier Frequency Offset and 2-D AoA Estimation Method for an OFDM-based Mobile Relay Station with Uniform Circular Array (등간격 원형 어레이를 갖는 OFDM 기반의 이동 릴레이를 위한 반송파 주파수 옵셋 및 2-D 입사각 추정 기법)

  • Ko, Yo-Han;Cho, Yong-Soo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.5A
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    • pp.423-431
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    • 2011
  • In this paper, carrier frequency offset and 2-D AoA (Angle-of-Arrival) estimation methods are proposed for an OFDM-based MRS (Mobile Relay Station) with UCA (Uniform Circular Array). The proposed methods are performed by using the preamble symbol in downlink and can improve the performance of CFO estimation significantly, compared with the conventional method. The proposed methods can be divided into two methods (method 1 and method 2) depending on the order of the AoA estimation and CFO estimation. It is shown by computer simulation under Mobile WiMAX environments that the proposed methods can estimate the CFOs and AoAs of adjacent BSs effectively.

Detection of Porcine Stress Syndrome from Genomic DNA of Hair Follicle by PCR-RFLP in Breeding Pig (종돈의 모근 Genomic DNA를 이용한 스트레스 증후군 검색)

  • 김계웅;김진우;유재영;박홍양
    • Reproductive and Developmental Biology
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    • v.28 no.1
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    • pp.37-43
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    • 2004
  • This study was carried out to investigate PSS (Porcine Stress Syndrome) with the PSE (Pale, Soft, Exudative) in 319 different pigs(Yorkshire 150; Landrace 89 and Duroc 80). The PCR-RFLP method was adapted to detect the ryanodine receptor (RYR 1) gene mutation and to estimate the genotype frequency of the RYR1 gene in breeding pig population. The DNA samples were collected from hair follicles of pigs of Yorkshire, Landrace and Duroc. After DNA amplification by PCR, the PCR products were digested by restriction enzyme, Cfo I. Primary PCR products of ryanodine receptor gene were length of 659 bp in hair follicle and their second PCR products were length of 522 bp in hair follicle. The exon region (522 bp) including point mutation ($C \arrow T; Arg \arrow Cys$) in the porcine ryanodine receptor gene, which is a causal mutation for PSS, was digested with Cfo I restriction enzyme. The RYR1 gene was classifed into three genotypes by agarose gel electrophoresis. The normal homozygous (NN) individuals showed two DNA fragments consisted of 439 and 83 bp. The mutant homozygous (nn) individuals showed only one DNA fragment 522 bp. In addition, all three fragments (522, 439 and 83 bp) were showed in heterozygous (Nn) carrier animals. The normal homozygous (NN), heterozygous (Nn) and mutant homozygous (nn) were 98.00, 2.00 and 0.00% in Yorkshire pigs, 87.64, 11.24 and 1.12% in Landrace, 100.00, 0.00 and 0.00% in Duroc, respectively. The gene frequencies of N and n were 0.990 and 0.010 in Yorkshire pigs, 0.933 and 0.067 in Landrace, 1.000 and 0.000 in Duroc, respectively.

Decision Feedback Equalizer Based on LDPC Code for Fast Processing and Performance Improvement (고속 처리와 성능 향상을 위한 LDPC 코드 기반 결정 궤환 등화기)

  • Kim, Do-Hoon;Choi, Jin-Kyu;Ryu, Heung-Gyoon
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.23 no.1
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    • pp.38-46
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    • 2012
  • In this paper, we propose a decision feedback equalizer based on LDPC(Low Density Parity Check) code for the fast processing and performance improvement in OFDM system. LDPC code has good error correcting capability and its performance approaches the Shannon capacity limit. However, it has longer parity check matrix and needs more iteration numbers. In our proposed system, MSE(Mean Square Error) of signal between decision device and decoder is fed back to equalizer. This proposed system can improve BER performance because it corrects estimated channel response more accurately. In addition, the proposed system can reduce complexity because it has a lower number of iterations than system without feedback at the same performance. Simulation results evaluate and show the performance of OFDM system with the CFO and phase noise in multipath channel.