• Smart Structures and Systems
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• 제24권3호
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• pp.345-360
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• 2019

The shear keys are set in a seismic isolation system to resist the long-term service loadings, and are cut off to isolate the earthquakes. This paper investigated the influence of shear keys on the seismic performance of a vertical spring-viscous damper-concave Coulomb friction isolation system by an incremental dynamic analysis (IDA) and a performance-based assessment. Results show that the cutting off process of shear keys should be simulated in a numerical analysis to accurately predict the seismic responses of isolation system. Ignoring the cutting off process of shear keys usually leads to untrue seismic responses in a numerical analysis, and many of them are unsafe for the design of isolated structure. And those errors will be increased by increasing the cutting off force of shear keys and decreasing the spring constant of shear keys, especially under a feeble earthquake. The viscous damping action postpones the cutting off time of shear keys during earthquakes, and reduces the seismic isolation efficiency. However, this point can be improved by increasing the spring constant of shear keys.

• 한국엔터테인먼트산업학회논문지
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• 제14권8호
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• pp.49-62
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• 2020

뮤지컬은 노래와 춤이 극의 플롯 전개에 긴밀하게 짜 맞추어진 연극으로 노래와 춤은 특정한 상황과 일련의 사건을 전개한다. 특히 노래는 등장인물이 지향하는 목표와 액션을 구체적으로 담아내면서 극의 중대한 변화를 일으키고 정서 환기와 증폭의 기능을 수행한다. 본 논문은 플롯 전개의 기능을 맡는 노래에 초점을 맞추어 '무대 위의 액션과 이야기를 구현하는 노래'를 '액션송'이라는 용어로 정의하고 그 역할과 중요성을 부각하고자 한다. '액션송'은 통합 뮤지컬의 극의 초반에 삽입되는 '캐릭터송'으로 부여받은 개인의 욕망이나 행동의 동기가 액션의 중심 사건인 갈등을 제공하면서 등장인물이 자신의 목표를 달성하기 위한 투쟁하는 과정을 다룬 노래이다. 즉, '액션송'은 무대 위의 액션을 가사가 있는 노래로 전달하여 음악과 서사를 유기적으로 결합한 노래를 뜻한다. 또한, 플롯을 앞으로 진전시키는(which move the plot forward) 노래이며 플롯 전개의 재료가 되는 일련의 사건 혹은 장면의 액션(Action)을 담은 노래이다. 본 논문은 우리에게 잘 알려지지 않은 '액션송'의 개념을 정리하고 연구의 토대를 마련하기 위한 것으로 뮤지컬 <공포의 꽃가게>를 대상으로 대본과 음악분석을 통해 '액션송'의 개념과 기능과 효용성을 알아보았다. 그 결과 액션송은 갈등으로 인한 긴장감을 축적하고 증폭시켜 극을 고조하게 만들며 관객의 감정몰입을 유도한다. 동시에 액션송 이후에 다음 장면에 대한 기대감을 상승시키면서 극의 재미와 흥미를 배가시키고 단일한 액션을 중심으로 한 극의 전개는 극의 내용을 선명하고 뚜렷하게 파악할 수 있게 만든다.

• 대한약리학회지
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• 제10권2호
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• pp.13-23
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• 1974

Results of an experiment on the general behavior of rats in order to explore the possible pharmacological actions of Panax Ginseng upon the central nervous system can be summarized as follows: 1) The rats treated with Ginseng-saponin intraperitoneally with the doses of 50 or 100 mg/kg show the decreased sleeping component and increase in lying and grooming component and walking and rearing component of general behavior. 2) There are no difference between control group and saline treated group in pattern of general behavior components. 3) In the Ginseng-saponin treated groups, the amphetamine stimulated walking and rearing component of genenarl behavior are reduced but lying and grooming component are elevated. 4) Ginseng-saponin shows very low acute toxicity in mice. The $LD_{50}$ in mice of 24 hours after intraperitoneal injection was 795 mg/kg. From the above findings, it is to suggest that the Ginseng saponin might stimulate the central nervous system but its mode of action appears to be different from that of amphetamine. And the effects of Ginseng saponin may be varied depending on various experimental situation or condition of animals.

• 약학회지
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• 제31권2호
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• pp.82-91
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• 1987

The effect of neurotoxic compound 6-hydroxydopamine (6-OHDA) on the change in blood pressure and contractile response of Vas deference by centrally acting agents has been studied in normal and DOCA-salt induced hypertensive rats. The treatment of neonatal rats with 6-OHDA (2$\times$100mg, 250mg Kg$^{-1}$s.c) significantly inhibited the antihypertensive and relaxant effects of Vas deference of clonidine(100$\mu\textrm{g}$ Kg$^{-1}$iv.). The simultaneous administration of desipramine with clonidine into neonatal rats decreased the antihypertensive response of clonidine although treated did not affect the relaxative response of Vas deference. Furthermore, the antihypertensive and relaxant responses of clonidine were reduced by the neonatal rats with 6-OHDA regardless of the administration of desipramine. When neonatal rats were administered with 6-OHDA, the development of DOCA-salt hypertension was prevented. These results suggest that 6-OHDA, clonidine and desipramine hada significant effect on the development and the inhibition of central hypertension mediating the central adrenergic neuron due to their affinity to the central nervous system.

• Structural Engineering and Mechanics
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• 제64권6권
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• pp.723-730
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• 2017

This paper studies on dynamic and stability behavior of a clamped-elastically restrained nanobeam under the action of a nonconservative force with an emphasis on the influence of surface properties on divergence and flutter instability. Using the Euler-Bernoulli beam theory incorporating surface effects, a governing equation for a clamped-elastically restrained nanobeam is derived according to Hamilton's principle. The characteristic equation is obtained explicitly and the force-frequency interaction curves are displayed to show the influence of the surface effects, spring stiffness of the elastic restraint end on critical loads including divergence and flutter loads. Divergence and flutter instability transition is analyzed. Euler buckling and stability of Beck's column are some special cases of the present at macroscale.

• Journal of Ginseng Research
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• 제16권1호
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• pp.18-23
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• 1992

Central dopaminergic activity of standardized ginseng extract G115 was investigated in comparison with those induced by haloperidol in rats. The effects of G115 on the locomotor activity and, stereotyped behavior induced by apomorphine, which interacts directly with dopamine receptor were observed. Apomorphine(2 mg/kg) significantly decreased locomotor activity, whereas it showed a markdly increased incidence of stereotyped behavior. Standardized ginseng extract G115(100 mg/kg) and haloperidol(1 mg/kg) showed a significant decrease in locomotor activity but not induced stereotyped hehavior. Locomotor activity induced by apomorphine was markdly decreased by haloperidol(1 mg/kg), but that was significantly increased by standardized ginseng extract G115(50 mg/kg). Stereotyped behavior induced by apomorphine was completely supressed haloperidol(1 mg/kg), but was not changed by standardized ginseng extract G115. These results suggest that standardized ginseng extract G115 plays an important role in central dopaminergic activity, and haloperidol and standardized ginseng extract G115 seem to have a different action in behavior.

• Steel and Composite Structures
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• 제47권2호
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• pp.203-216
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• 2023

The composite beam connections often encountered fracture failure in the welded bottom flange joint, and a bottom flange bolted connection has been proposed to increase the deformation ability of the bottom flange joint. The seismic performance of the bottom flange bolted composite beam connection was suffered from both the composite action of concrete slab and the asymmetric load transfer mechanisms between top and bottom beam flange joints. Thus, this paper presents a comprehensive numerical study on the working mechanism of the bottom flange bolted composite beam connections. Three available modelling methods and a new modelling method on the flange-stud-slab interactions were compared. The efficient numerical modeling method was selected and then applied to the parametric study. The influence of the composite slab, the bottom flange bolts, the shear composite ratio and the web hole shape on the seismic performance of the bottom flange bolted composite beam connections were investigated. A hogging strength calculation method was then proposed based on numerical results.

• 생약학회지
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• 제17권4호
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• pp.272-279
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• 1986

This study was conducted about the effect of Shihogesikungang-tang on the central nervous system and cardiovascular system for the investigation of its clinical effect based on the Oriental medicinal references. The results of this study were summerized as follows; Analgesic activity as evaluated by the writhing syndrome in mice was significantly noted. A decrease effect of the spontaneous movement as estimated by wheel cage method, muscle relaxant effect as evaluated by the rotor rod method and the prolonged effect of sleeping time induced by thiopental-Na were significantly shown in mice. A antipyretic activity in febrile rats induced by the endotoxin was recognized. Anti-inflammatory effect in carrageen-induced paw edema in rats was significantly noted. Negative inotropic action on the isolated heart of frogs was noted. A vasodilative action in rabbits peripheral blood vessels and hypotension in anesthetized rabbits were remarkably recognized.

• Fashion, Industry and Education
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• 제15권2호
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• pp.36-52
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• 2017

In this study, we tried to understand preschooler clothing trends and identify the purchase behaviors of various consumers, such as grandparents, aunts, uncles, and parents, who are the main consumers of the preschooler clothing market. We conducted in-depth interviews with consumers who were interested in preschooler clothing, purchased it frequently, and bought preschooler clothing within the last three months. Their purchase motivations and purchase behaviors were analyzed through exploratory and inductive analysis. The analysis was conducted by integrating categories into one process centered on core categories through open coding, axial coding, and selective coding. The results of this study included that 1) a variety of clothing purchase behaviors appeared as a central phenomenon, 2) the causal conditions that contributed to this phenomenon were the buyers' childcare experiences, purchase experiences, the personal consumption values of individuals, and income levels, 3) in response to the central phenomenon, the parents' action/interaction strategies were acceptance and rejection of purchased clothing, 4) contextual and Intervening conditions affecting action/interaction strategy were family environment changes, the VIB (Very Important Baby) phenomenon, parents' clothing involvement, and the relationship with the buyers, and acceptance by the users, and 5) as a result of the strategy expressed as acceptance and rejection, various clothing behaviors emerged. In this study, we identified that there are various influencers, apart from parents, involved in children's clothing consumption. Therefore, we need to keep in mind that various purchase behaviors and clothing trends that appear during one's childhood may affect the individual's clothing behavior in the future.

• Biomolecules & Therapeutics
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• 제2권4호
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• pp.347-360
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• 1994

The general and some pharmacological actions of DWP 301 were investigated in animals and the following results were obtained. In central nervous system, DWP 301 had no effects on the pentobarbital induced anaesthesia, rotarod test, traction test, analgesic action, anticonvulsant action in mice and body temperature in rat. But DWP 301 showed a little decrease of locomotor activity at a dose of 3,000 mg/kg. From these results, DWP 301 was considered to have little pharmacological effect on the central nervous system. Furthermore, DWP 301 had no influences on the normal blood pressure and heart rate. DWP 301 showed no effect on the isolated guinea pig ileum, trachea, right atrium, and nonpregnant rat uterus. But, in the isolated guinea pig vas deference, DWP 301 had showed inhibitory effect on the contractions produced by norepinephrine. DWP 301 showed rise of gastric juice pH and decrease of urine volume. Also, DWP 301 had no effect on the gastrointestinal motility and blood aggregation. From these results, it is concluded that the general pharmacological effect of DWP 301 are similar to or weaker than M and AGA.