• CELLMED
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• v.14 no.3
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• pp.68.1-68.4
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• 2024

Objective: Study on a case of improvement of depression through the use of OCNT Methods: OCNT was implemented due to depression that lasted over prolonged period time on a 59-year old Korean female. Results: Depression gradually improved a little by little following the implementation of OCNT and symptoms improved eventually to the extent of enabling the patient to engage in internal and external activities. Conclusion: Application of OCNT to those suffering from depression can be helpful in alleviation of symptoms.

• CELLMED
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• v.14 no.3
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• pp.69.1-69.3
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• 2024

Objective: A Case of improvement of hyperlipidemia through the use of OCNT. Methods: A Korean female in her 40s has been suffering from a wide range of symptoms due to hyperlipidemia. Results: Hyperlipidemia was improved following implementation of OCNT. Conclusion: Application of OCNT on hyperlipidemia can be helpful in alleviation of symptoms.

• CELLMED
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• v.14 no.3
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• pp.70.1-70.3
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• 2024

Objective: Report of a case of improvement of hair loss through the use of OCNT. Methods: A 60-year old Korean male has been suffering from hair loss. Results: Hair loss was markedly improved following implementation of OCNT. Conclusion: Application of OCNT to hair loss can be helpful in alleviation of the symptoms.

• CELLMED
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• v.14 no.4
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• pp.71.1-71.3
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• 2024

Objective: Improvement of angina pectoris using OCNT Methods: OCNT was applied to a Korean woman in her 60s who was experiencing chest pain and dizziness due to angina pectoris for about six months. Results: After starting OCNT, symptoms of chest pain and dizziness due to angina pectoris gradually decreased, and after about six months, such symptoms no longer caused discomfort. Conclusion: For patients with angina pectoris who experience chest pain and dizziness, OCNT can help relieve symptoms.

• CELLMED
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• v.14 no.1
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• pp.66.1-66.3
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• 2024

Objective: To improve the symptoms of patients with urolithiasis and chronic dyspepsia using OCNT. Methods: A 60-year-old Korean male who had undergone extracorporeal shock wave lithotripsy six times without natural stone removal was treated with OCNT for two weeks. Results: The stones were removed through adequate hydration and light exercise while undergoing OCNT. Conclusion: The application of OCNT in patients with urolithiasis can be beneficial in alleviating symptoms.

• IMMUNE NETWORK
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• v.2 no.4
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• pp.183-188
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• 2002

Gradual attrition of telomere to a critical short length elicits successive cellular response of cellular senescence and crisis. Cancer cells evade this process by maintaining functional telomeres via one of two known mechanisms of telomere maintenance. The first and most frequent mechanism involves reactivation of enzyme activity of telomerase, a ribonucleoprotein complex mainly via transcriptional up-regulation of TERT, a catalytic subunit of telomerase complex. The second mechanism utilizes telomerase-independent way termed ALT (for Alternative Lengthening of Telomere), which possibly involves recombination pathways. Thus master key for cellular immortalization is supposed to possess adequate telomere reserves. Indeed, telomerase can alone induce the immortalization under culture on feeder cell layers without generally known inactivation mechanism of tumor suppressor genes. Including this phenomena, this review will focus on telomerase and telomere-associated proteins, thereby implication of these proteins for cellular immortalization processes.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.11
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• pp.1582-1585
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• 2004

The antioxidative ability on the basis of reduced glutathione sulphydryl level, the inhibition activities of linoleic acid peroxidation of cell free extract of Lactobacillus spp. and the effects of types of media and growth phase of the cells on the cellular GSH level have been determined. Correlation between reduced glutathione sulphydryl level and antioxidative ability of Lactobacillus spp. was analyzed: Lactobacillus casei HY 2782 contained 25.15 $\mu$mole/g of GSH, the cellular GSH level of L. casei HY 2782 reached maximum after 24 h of cultivation and tended to decrease on further cultivation up to 72 h. There was a significantly higher level of cellular GSH when grown in de Man Rogosa and Sharpe (MRS) broth than in tryptone phytone yeast extract (TPY) broth or bromcresol pruple dextrose (BCP) broth (p<0.05). The antioxidant activity of cell free extract of Lactobacillus spp. have been shown to be significantly different among strains in the inhibition of linoleic acid peroxidation by thiobarbituric acid (TBA) test (p<0.01). L. casei HY 2782 and L. acidophilus ATCC 4356 revealed a high degree of antioxidative effect in linoleic acid oxidation system. Spearmans' rank correlation coefficient between inhibitory activity on linoleic acid peroxidation and cellular GSH levels of Lactobacillus spp. was 0.65, which means a significant positive correlation.

• BMB Reports
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• v.33 no.1
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• pp.59-62
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• 2000

Hepatitis C virus (HCV) nonstructural 5B (NS5B) protein is an RNA-dependent RNA polymerase (RdRp). To determine whether it can contribute to viral replication by interaction with cellular proteins, the yeast two-hybrid screening system was employed to screen a human liver cDNA library. Using the HCV NS5B as a bait, we have isolated positive clones encoding a cellular protein. The NS5B interacting protein, 5BIP, is a novel cellular protein of 170 amino acids. Interaction of the HCV NS5B protein with 5BIP was confirmed by a protein-protein blotting assay. Recently, we have demonstrated that NS5B possesses an RdRp activity and thus it is possible that 5BIP, in association with NS5B, plays a role in HCV replication.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.7 no.1
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• pp.1-18
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• 2001

Objective: This experimental study was carried out to evaluate the effects of Saussurea Radix and Plantaginis Herba on cellular viability, proliferation, apoptosis and expression of the cell cycle-related genes in cultured gastric cancer cells. Method :MTT assay for analysis of cellular toxicity and the effect on suppression of cellular viability, $[^{3}H]$ thymidine incorporation assay for evaluation of the effect on suppression of DNA replication, tryphan blue exclusion assay for measurement of induction of apoptosis and Quantitative RT-PCR for analysis of the effects on expression of cell cycle or apoptosis-related genes were performed. Results: Antitumor activity of Saussurea Radix associated with inhibition of cell cycle progression and promotion of apoptosis caused by transcriptional regulation of p53, p21/Wafl and the other related genes was observed.

• ETRI Journal
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• v.38 no.1
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• pp.81-89
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• 2016

In this paper, a beam ID preamble (BIDP) technique, where a beam ID is transmitted in the physical layer, is proposed for efficient beam training in millimeter-wave cellular communication systems. To facilitate beam ID detection in a multicell environment with multiple beams, a BIDP is designed such that a beam ID is mapped onto a Zadoff-Chu sequence in association with its cell ID. By analyzing the correlation property of the BIDP, it is shown that multiple beams can be transmitted simultaneously with the proposed technique with minimal interbeam interference in a multicell environment, where beams have different time delays due to propagation delay or multipath channel delay. Through simulation with a spatial channel model, it is shown that the best beam pairs can be found with a significantly reduced processing time of beam training in the proposed technique.