• Molecules and Cells
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• v.22 no.3
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• pp.328-335
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• 2006

Imperatoxin A ($IpTx_a$), a 3.7 kDa peptide from the African scorpion Pandinus imperator, is an agonist of the skeletal muscle ryanodine receptor (RyR1). In order to study the structure of the toxin and its effect on RyR1, $IpTx_a$ cDNA was PCR-amplified using 3 pairs of primers, and the toxin was expressed in E. coli. The toxin was further purified by chromatography, and various point mutants in which basic amino acids were substituted by alanine were prepared by site-directed mutagenesis. Studies of single channel properties by the planar lipid bilayer method showed that the recombinant $IpTx_a$ was identical to the synthetic $IpTx_a$ with respect to high-performance liquid chromatography mobility, amino acid composition and specific effects on RyR1. Mutations of certain basic amino acids ($Lys^{19}$, $Arg^{23}$, and $Arg^{33}$) dramatically reduced the capacity of the peptide to activate RyRs. A subconductance state predominated when $Lys^8$ was substituted with alanine. These results suggest that some basic amino acid residues in $IpTx_a$ are important for activation of RyR1, and that $Lys^8$ plays an important role in regulating the gating mode of RyR1.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.3
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• pp.519-525
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• 2014

In this paper, we show a scheme to directly access DLNA network with the 3G/4G communication module of a smartphone in home or office environment. By exploiting this scheme, end users can use DLNA service more conveniently regardless of the type of activated communication module in a smartphone. For the implementation of this scheme, we use a femtocell that is a basestation with small coverage. A problem caused by the IP address hierarch discrepancy between the IP address of 3G/4G module of smartphone and those of local network nodes is resolved by deploying local IP address scheme. The processing of multicasting packet, that is required in DLNA service, is enabled by using IP tunneling scheme. As a result, end user can access DLNA network regardless of the type of activated wireless communication module. We validate the design result by implementing it on a commercial WCDMA femtocell.

• Journal of Communications and Networks
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• v.7 no.2
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• pp.192-206
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• 2005

Integration of mobile networks and Internet has started with 2.5 generation of mobile cellular networks. Internet traffic is today dominant traffic type worldwide. The hanger for higher data rates needed for data traffic and new IP based services is essential in the development of future wireless networks. In such situation, even 3G with up to 2 Mbit/s has not provided data rates that are used by Internet users with fixed broadband dial-up or through wired local area networks. The solution to provide higher bit rates in wireless access network has been found in wireless LAN although initially it has been developed to extend wired LAN into wireless domain. In this paper, we propose and describe a solution created for interoperability between mobile cellular network and WLAN. The integration between two networks, cellular and WLAN, is performed on the authentication, authorization, and accounting, i.e., AAA side. For that purpose we developed WLAN access controller and WLAN AAA gateway, which provide gateway-type access control as well as charging and billing functionalities for the WLAN service. In the development process of these elements, we have considered current development stadium of all needed network entities and protocols. The provided solution provides cost-effective and easy-to-deploy PLMN-WLAN Internetworking scenario.

• Microbiology and Biotechnology Letters
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• v.25 no.6
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• pp.592-597
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• 1997

During the screening of inhibitors against phospholipase C (PLC) and the formation of inositol phosphates (IP$_{t}$) at NIH3T3${\gamma}$1 cells from microbial secondary metabolites, we selected a fungal strain MT60109 which was capable of producing an inhibitor. By the taxonomic studies, this fungus was identified as Pseudallescheria sp. MT60109 and an inhibitor of PLC was purified by BuOH extraction and chromatographic techniques from the culture broth of Pseudallescheria sp. MT60109. The inhibitor was identified as thielavin B by the physico-chemical properties and spectroscopic analysis of UV, FAB-MS, $^{1}$H, $^{13}$C-NMR, $^{1}$H-$^{1}$H COSY and HMBC. Thielavin B showed potent inhibitory activity against PLC purified from bovine brain with an IC$_{50}$ of 20 $\mu$M. And it also inhibited the formation of inositol phosphates in platelet-derived growth factor (PDGF) -stimulated NIH3T3${\gamma}$1 cells with an IC$_{50}$ of 20 $\mu$M.

• Proceedings of the Korean Information Science Society Conference
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• 2007.06d
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• pp.100-104
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• 2007

라디오 주파수를 이용하여 사물의 정보를 인식할 수 있는 RFID 기술은 다양한 분야에 활용되고 있는데 이러한 RFID 망을 All-IP 기반의 이동통신망과 연동할 경우 RFID의 각종정보와 휴대단말기의 위치정보 및 이동성, 그리고 다양한 IP 기반의 정보서버를 활용한 새로운 형태의 위치기반 서비스의 창출이 가능하다. 즉, RFID 태그에 태그 리더기 역할을 하는 단말기의 위치를 부여하고 이를 RFID 서버에서 지속적으로 관리함으로써 RFID 태그의 Code와 위치를 기반으로 한 위치기반서비스를 제공할 수 있다. 본 연구에서는 RFID망과 이동통신망의 연동을 기반으로 한 위치기반서비스 모델로 Mobile Information Retrieval Service (MIRS), Mobile Location Tracking Service (MLTS), Localization Service by Fixed Tag (LSFT) 세 가지 모델을 제시하였으며 이러한 서비스 모델은 실제 서비스를 개발하는데 있어 다양한 방식으로 활용될 수 있다.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04a
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• pp.550-552
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• 2004

현재 MANET에 관한 대부분의 연구는 라우팅문제에 초점을 맞추고 있다. 하지만 우리는 MANET에서 응용될 수 있는 시스템에 대하여 관심을 갖게 되었다. 특히 셀룰라망(Cellular network)의 단점, 즉 처리량(Throughput)이 낮고 독립적인 망 구축과 데이터 서버로의 접근이 용이하지 않다는 것을 보완하기 위한 802.11기반 위치기반서비스(LBS： Location Based Service)라는 응용 시스템을 제안하게 되었고 MANET에서의 동적 IP 주소 할당과 웹 기반 응용프로그램(Web based application)을 구현하였다. 본 논문에서는 이동적응 망에서의 802.11기반 위치기반서비스에서 필요한 서비스발견(Service discovery)과 등록(Service registration), 동적 IP 주소 할당, 라우팅(Routing)과 웹 기반 응용프로그램(Web based application)을 연동한 시스템 프로토타입을 제안하고 구현한다.

• Journal of Communications and Networks
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• v.14 no.5
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• pp.487-494
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• 2012

A standard paradigm for the allocation of wireless resources in communication demands symmetry, that is, all users are assumed to be on equal footing and hence get equal shares of the system's communication capabilities. However, there are situations in which "prime users" should be given priority, as for example in the transmission of emergency messages. We examine prioritization policies that could be implemented at the physical layer and propose a new one, termed interference priority (IP), which is shown to have excellent performance. We evaluate the performance of these prioritization techniques both in controlled settings and within the context of a full cellular system and discuss the impact of prioritized use of resources on the unprioritized users.

• Proceedings of the Korea Information Processing Society Conference
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• 2009.11a
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• pp.551-552
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• 2009

조선산업에서 선박의 건조 과정 중 탑재 공정은 작업자 간의 긴밀한 통신을 필요로 하며 매우 위험한 작업이다. 이러한 작업을 음성 품질이 매우 열악한 무전기나 호접속 지연이 많은 주파수 공용통신(TRS)를 이용하여 통신을 하고 있어 매우 위험하다. 따라서, 이러한 기존 통신방식을 대체하는 IP 기반 그룹통신 시스템과 이에 대한 품질 측정 및 평가가 필요하다. 본고에서는 IP 멀티미디어 시스템의 최초의 서비스인 PoC(PTT over Cellular) 서비스를 기반으로 조선산업에서 통합통신(Unified Communication)을 지향하기 위하여, 강재로 인한 매우 열악한 비가시 거리(NLOS)를 극복하고, 효율적인 통신 서비스를 제공하기 위한 엔터프라이즈 PoC을 기반으로 그룹통신의 품질을 측정하고 평가하였다. WiBro 기반 엔터프라이즈 PoC 서비스는 실제적으로 적용이 가능할 뿐 아니라, 실제의 작업자가 통신할때 지연이 느껴지지 않는 1초 이내의 그룹통신 지연시간에 대해 상기 서비스를 분석하였으며, 이론 상으로는 충분히 제공 가능함을 보이고 있다.

• Proceedings of the Korean Information Science Society Conference
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• 2002.10e
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• pp.649-651
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• 2002

이동 컴퓨팅 환경에서 양질의 멀티미디어 서비스를 제공하기 위해서는 트래픽에 대한 QoS가 보장되어야 한다. 그러나 기존의 자원 예약 기법은 유선 네트워크를 위해 설계된 것이므로 무선 이동 네트워크에서의 QoS 보장 문제를 상당부분 해결하지 못하고 있는 실정이다. 또한 최근에는 마이크로 셀들로 구성된 네트워크가 증가함에 따라 빈번한 핸드오프로 인한 전송지연 문제와 이동호스트(MN: Mobile Node)의 위치 이동을 신속하게 제어해야 하는 문제 등이 발생하고 있다. 따라서 이러한 마이크로 셀룰러 환경에서는 기존의 Mobile IP와 RSVP 연동기법을 사용하는 것만으로는 한계가 있다. 본 논문에서는 마이크로 셀룰러 네트워크에서 QoS를 보장하기 위해 CRSVP(Cellular RSVP Protocol)라는 새로운 프로토콜을 제안한다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.2 no.4
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• pp.171-183
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• 2008

Nowadays, wireless packet data services are provided over Wireless MAN (WMAN) at a high data service rate, while 3G cellular networks provide wide-area coverage at a low data service rate. The integration of mobile WiMAX and 3G networks is essential, to serve users requiring both high-speed wireless access as well as wide-area connectivity. In this paper, we propose a cross-layer optimization scheme for a vertical handover between mobile WiMAX and 3G cellular networks. More specifically, L2 (layer 2) and L3 (layer 3) signaling messages for a vertical handover are analyzed and reordered/combined, to optimize the handover procedure. Extensive simulations using ns-2 demonstrate that the proposed scheme enhances the performance of a vertical handover between mobile WiMAX and 3G networks: low handover latency, high TCP throughput, and low UDP packet loss ratio.