• Title/Summary/Keyword: Cell deformation

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A Meshfree procedure for the microscopic analysis of particle-reinforced rubber compounds

  • Wu, C.T.;Koishi, M.
    • Interaction and multiscale mechanics
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    • v.2 no.2
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    • pp.129-151
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    • 2009
  • This paper presents a meshfree procedure using a convex generalized meshfree (GMF) approximation for the large deformation analysis of particle-reinforced rubber compounds on microscopic level. The convex GMF approximation possesses the weak-Kronecker-delta property that guarantees the continuity of displacement across the material interface in the rubber compounds. The convex approximation also ensures the positive mass in the discrete system and is less sensitive to the meshfree nodal support size and integration order effects. In this study, the convex approximation is generated in the GMF method by choosing the positive and monotonic increasing basis function. In order to impose the periodic boundary condition in the unit cell method for the microscopic analysis, a singular kernel is introduced on the periodic boundary nodes in the construction of GMF approximation. The periodic boundary condition is solved by the transformation method in both explicit and implicit analyses. To simulate the interface de-bonding phenomena in the rubber compound, the cohesive interface element method is employed in corporation with meshfree method in this study. Several numerical examples are presented to demonstrate the effectiveness of the proposed numerical procedure in the large deformation analysis.

Mucolipidosis Type II in Vietnam

  • Vu, Chi Dung
    • Journal of mucopolysaccharidosis and rare diseases
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    • v.2 no.1
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    • pp.31-31
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    • 2016
  • Purpose: To describle clinical features and enzyme activity of Vietnamese patients with Mucolipidosis type II. Methods: Clinical features, laboratory and plasma lysosom enzyme activity by 4 MU-Fluorometric assay was studied from 2014-2015 at the Northern referral center of Pediatrics - National Children's Hospital. Results: 16 cases (7 girls and 9 boys) were diagnosed with I-cell bases on clinical symptoms and enzyme activities studies. Diagnosis age was $5.93{\pm}4.28$ years, onset age was recognised from birth to 4 years (median 1.25) with the feature of joint stiffness and bone deformation. All cases presented with the feature of joint stiffness, chest deformation and kyphoscoliosis; Fifteen cases (93.7%) had coarse facial features. No patients had hepatosplenomegaly on abdominal ultrasound, 5/15 patients had heart valves disease. Enzyme assay showed ${\alpha}$-Hexosaminidase of $1,885.9{\pm}338.7$ (nmol/mg plasma/17 hrs), ${\alpha}$-Iduronate sulfatase of $4,534.8{\pm}1,062.9nmol/mg$ plasma/4 hrs). Conclusion: Mucolipidosis II seriously affected the life of the patients with skeletal deformities, contractures develop in all joints and cardiac involvement.

Numerical and Exprimental Study of the Air Plate in a Fuel Cell Considering Structural Deformation (연료전지 공기판의 구조적 변형을 고려한 유동 해석과 실험)

  • Yang, Ji-Hae;Hahn, Oh-Hyun;Park, Jung-Sun
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.32 no.5
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    • pp.41-49
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    • 2004
  • The porous media of a proton exchange membrane fuel cell (PEMFC) is made of deformable materials. The shape of cross sectional area in air plate channels has been changed by structural deformation of the porous media. The uniform mass flow rate and pressure are major factors for safe and efficient operation in the PEMFC. Two kinds of models are provided for the flow analyses. Deformable and undeformable porous media are considered for numerical analysis and experiment of the air plate model. The numerical flow analysis results with deformable and undeformable porous media has some discrepancy in pressure distribution. The pressure differences are measured in order to compare with numerical analysis results. Pressures are measured between inlet and outlet of the air plate. The numerical analysis and experimental results show similar pressure distribution. It is shown that the pressure drops in the two approaches are well matched each other. It is proven that the consideration of structural deformation is required in the numerical analysis/experiment for the PEMFC design.

Analysis of Three Dimensional Equal Chanel Angular Pressing by Using the Finite Element Method in Conjunction with the Dislocation Cell Based Constitutive Model (전위 셀 구성모델을 결합한 유한요소법을 이용한 3차원 등통로각압출 공정 해석)

  • Yoon, Seung Chae;Kim, Hyoung Seop
    • Korean Journal of Metals and Materials
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    • v.47 no.11
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    • pp.699-706
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    • 2009
  • Deformation behavior of pure aluminum during equal channel angular pressing (ECAP) was simulated using a three-dimensional version of the finite element method in conjunction with a constitutive model based on the dislocation density and cell evolution. The three-dimensional finite element analyses for the prediction of microstructural features, such as the variation of the dislocation density and the cell size with the number of ECAP, are reported. The calculated stress and strain and their distributions are also investigated for the route Bc ECAP processed pure aluminum. The results of finite element analyses are found to be in good agreement with experimental results for the dislocation cell size. Due to the accumulation of strain throughout the workpiece and an overall trend to saturation in cell size, a decrease of the difference in cell size with the number of passes (1~4) was predicted.

Fast Planar Shape Deformation using a Layered Mesh (계층 메쉬를 이용한 빠른 평면 형상 변형)

  • Yoo, Kwang-Seok;Choi, Jung-Ju
    • Journal of the Korea Computer Graphics Society
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    • v.17 no.3
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    • pp.43-50
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    • 2011
  • We present a trade-off technique for fast but qualitative planar shape deformation using a layered mesh. We construct a layered mesh that is embedding a planar input shape; the upper-layer is denoted as a control mesh and the other lower-layer as a shape mesh that is defined by mean value coordinates relative to the control mesh. First, we try to preserve some shape properties including user constraints for the control mesh by means of a known existing nonlinear least square optimization technique, which produces deformed positions of the control mesh vertices. Then, we compute the deformed positions of the shape mesh vertices indirectly from the deformed control mesh by means of simple coordinates computation. The control mesh consists of a small number of vertices while the shape layer contains relatively a large number of vertices in order to embed the input shape as tightly as possible. Since the time-consuming optimization technique is applied only to the control mesh, the overall execution is extremely fast; however, the quality of deformation is sacrificed due to the sacrificed quality of the control mesh and its relativity to the shape mesh. In order to change the deformation behavior and consequently to compensate the quality sacrifice, we present a method to control the deformation stiffness by incorporating the orientation into the user constraints. According to our experiments, the proposed technique produces a planar shape deformation fast enough for real-time applications on limited embedded systems such as cell phones and tablet PCs.

Graphene accelerates osteoblast attachment and biomineralization

  • Ren, Jia;Zhang, Xiaogang;Chen, Yao
    • Carbon letters
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    • v.22
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    • pp.42-47
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    • 2017
  • In this paper, the in vitro biocompatibility of graphene film (GF) with osteoblasts was evaluated through cell adhesion, viability, alkaline phosphatase activity, F-actin and vinculin expressions, versus graphite paper as a reference material. The results showed that MG-63 cells exhibited stronger cell adhesion, better proliferation and viability on GF, and osteoblasts cultured on GF exhibited vinculin expression throughout the cell body. The rougher and wrinkled surface morphology, higher elastic modulus and easy out-of-plane deformation associated with GF were considered to promote cell adhesion. Also, the biomineralization of GF was assessed by soaking in simulated body fluid, and the GF exhibited enhanced mineralization ability in terms of mineral deposition, which almost pervaded the entire GF surface. Our results suggest that graphene promotes cell adhesion, activity and the formation of bone-like apatite. This research is expected to facilitate a better understanding of graphene-cell interactions and potential applications of graphene as a promising toughening nanofiller in bioceramics used in load-bearing implants.

Study on the prediction about thermal deformation of thin film solar cell according to metal substrates (금속기판재에 따른 박막형 태양전지의 열변형량 예측에 관한 연구)

  • Koo, Seung-Hyun;Lee, Heun-Yeol;Yim, Tai-Hong
    • 한국신재생에너지학회:학술대회논문집
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    • 2007.11a
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    • pp.285-288
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    • 2007
  • 박막형 태양전지 및 플렉서블 태양전지 기판으로 사용되는 금속기판의 우수성은 잘 알려져 있다. 그러나 상용 금속기판이 직면하고 있는 문제점을 보완하기 위해서 전주법으로 제조된 2원합금 금속포일을 개발하였으며, 박막형 및 플렉서블 태양전지의 기판재로 적용가능성을 확인하였다. 일반적으로 태양전지를 제조할 때 열 공정이 수행되며, 이때 기판재와 cell을 구성하는 반도체의 열팽창 계수 차이에 의한 열변형으로 결함이 발생될 수 있고, 태양전지 효율 및 수명을 저하시키는 원인이 될 수 있다. 이러한 원인이 될 수 있는 구성 재료간의 열팽창계수 차이에 의한 cell 의 변형량을 추정하기 위해 유한요소해석 방법을 사용하였다. 유한요소해석을 수행하기 위해 ALGOR 라는 해석 tool 을 사용하였다. 유한요소해석 수행에 사용된 상용 금속인 Mo, Ti, Al, SUS 포일과 전주법으로 제조된 2원합금 금속포일의 열팽창 계수는 실험을 통한 측정치이며, cell을 구성하는 반도체의 열팽창 계수와 열특성은 참고 문헌에 있는 자료들이다. 이 값들을 기반으로 cell 의 구성을 단순화시킨 가상의 태양전지가 제조 공정 온도에서 상온으로 냉각될 때의 열변형량을 계산하였다.

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Development of Thermal Management System Heater for Fuel Cell Vehicles (연료전지 자동차용 TMS 히터 개발)

  • Han, Sudong;Kim, Sungkyun;Kim, Chimyung;Park, Yongsun;Ahn, Byungki
    • Journal of Hydrogen and New Energy
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    • v.23 no.5
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    • pp.484-492
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    • 2012
  • The TMS(Thermal Management System) heater in a fuel cell vehicle has been developed to prevent a decline of fuel cell durability and cold start durability. Main functions of the COD(Cathode Oxygen Depletion) heater are depletion of oxygen in a cathode as heat energy and consumption of electric power for rapid warming up of a fuel cell stack. This paper covers subjects including the design specification of a heater, heater controller for detection of overheat and reliability assessment including coolant pressure cycle test of a heater. To verify the design concept, burst pressure and deformation analysis of plastic housing were carried out. Also, temperature distribution analysis of heater surface and coolant inside of housing were carried out to verify the design concept. By designing the plastic housing instead of a steel housing, the 30% weight lightening and 50% cost reduction were attained. A module-based design of a TMS system including a heater or reducing the watt density of a heater is a problem to be solved in the near future work.

Microstructural Characteristics of the Ordered and Disordered Leaves in Citrus junos Sieb.

  • Park, Min-Hee;Boo, Hee-Ock;Kim, Hong-Sub;Lee, Sook-Young
    • Plant Resources
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    • v.3 no.3
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    • pp.163-172
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    • 2000
  • We compared microstructural features of the ordered cell and disordered leaves in Citrus junos Sieb. by electron microscopy. In the cell of the ordered leaves, many chloroplasts and large vacuoles were particularly observed. Also a lot of vessel, companion cell and big nucleus were presented in vascular bundle regions. The mitochondria and the other organelles were interspersed among the chloroplasts in a thin, peripheral layer of cytoplasm. The chloroplast possessed typical grana and intergranal lamellae, numerous starch grains and a few small osmophilic globules. Besides, microbodies were closely associated with the mitochondria and the chloroplast. The process of the formation of the secondary cell wall from primary cell wall was observed the vessel elements, the tonoplast wall and the secondary cell wall. It was observed that the oil sac with the unique perfume distributed the adjacent cell wall. In the cell of disordered leaves, the all of the organelles were thrust toward the cell wall due to the fusion of vacuoles in the cells. It was observed that a lot of the very small particles spreaded in the cytoplasm. The loss of unique perfume of the leaves was resulted in the destruction of the oil sac. Also, there was not observed grana, lamellae, starch and osmophillic globules in the chloroplast. The small distributed organelles was not observed but the elongation of the cell wall was proceed no longer. Therefore, the plasma membrane diverged from the cell wall. All of organelles in the cell had poor function and deformation. A massive vacuole was fulfilled in single cell and the vacuole contains a lot of large and small particles. The organelles were presented on the side of the cell wall according to the enlargement of vacuole and they were observed to be breakdown.

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Cytological Modification of Sorghum Leaf Tissues Showing the Early Acute Response to Maize Dwrf Mosaic Virus

  • Choi, Chang-Won
    • Journal of Plant Biology
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    • v.39 no.3
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    • pp.215-221
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    • 1996
  • Sorghum leaf tissues showing the early acute response of systemic infection with maize dwarf mosaic virus (MDMV) strain A, contained unusual virus-induced cytological modifications including cell wall thickenings and protrusions, intercellular vesicles termed as "paramural bodies", modified plasmodesmata, abnormal plastids, and cylindrical inclusion bodies. Abnormal cell wall, some of which associated with paramural bodies, was frequently contained modified plasmodesmata. Various abnormal plastids were located within infected cells of leaf tissues showing the early acute response. The most important changes in chloroplast seen in the tissues are the presence of small vesicles, deformation of membranes, reduction in granal stack height, disappearance of osmiophilic globules and degeneration of stuctures. The cytological modification was not occurred in nucleus but a group of degenerated mitochondria with abnormal membranes attached to cylindrical inclusion bodies were observed. It was hard more or less to prove the relationship clearly between virus and cellular organelles in virus replication.plication.

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