• Title/Summary/Keyword: Cell analysis

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Spindle Cell (Sarcomatoid) Carcinoma of the Larynx : A Case Report (후두에 발생한 방추세포암종 1예)

  • Hong, Ki-Min;Jung, Gi-Hwa;Lim, Jae-Yol;Choi, Jeong-Seok
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.25 no.1
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    • pp.39-41
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    • 2014
  • Spindle cell carcinoma is an uncommon type of squamous cell carcinoma characterized by a mixture of malignant epithelial and mesenchymal cells. Most spindle cell tumors are polypoid and pedunculated. It is usually detected at an early stage, removed by laryngoscope guided polypectomy at the time of diagnosis, and seems to have good prognosis. The tools for diagnosing spindle cell carcinoma are histopathological analysis and immunohistochemical analysis. With reviews of literature, we report a 72-year-old patient complaining of hoarseness and dysphagia who was later diagnosed as spindle cell carcinoma.

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Establishment and Identification of a Debao Pony Ear Marginal Tissue Fibroblast Cell Line

  • Zhou, X.M.;Ma, Y.H.;Guan, W.J.;Zhao, D.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.10
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    • pp.1338-1343
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    • 2004
  • The Debao pony ear marginal tissue fibroblast cell line (NDPEM 2/2) was uccessfully established using either primary explant technique or collagenase technique. The characterizations of the cell line were identified as following: the cells were adherent and of density limitation; population doubling time (PDT) of cells made with the two techniques were 35.9 h and 48 h, respectively; chromosome analysis showed that the frequency of cell chromosome number to be 2n=64 was 91.3%-92.8%. Confirmed by isoenzyme analysis, this cell line had no cross- contamination. Tests for microbial contamination from bacteria, fungi, virus or mycoplasma were negative. This newly established cell line meets all the standard quality controls of ATCC. It will provide a precious genetic resource for the conservation of the Debao pony breed, as well as effective experimental material for genetic studies on Debao ponies.

Cell Cycle Regulation in the Budding Yeast

  • Nguyen, Cuong;Yoon, Chang-No;Han, Seung-Kee
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2005.09a
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    • pp.278-283
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    • 2005
  • Cell cycle is regulated cooperatively by several genes. The dynamic regulatory mechanism of protein interaction network of cell cycle will be presented taking the budding yeast as a sample system. Based on the mathematical model developed by Chen et at. (MBC, 11,369), at first, the dynamic role of the feedback loops is investigated. Secondly, using a bifurcation diagram, dynamic analysis of the cell cycle regulation is illustrated. The bifurcation diagram is a kind of ‘dynamic road map’ with stable and unstable solutions. On the map, a stable solution denotes a ‘road’ attracting the state and an unstable solution ‘a repelling road’ The ‘START’ transition, the initiation of the cell cycle, occurs at the point where the dynamic road changes from a fixed point to an oscillatory solution. The 'FINISH' transition, the completion of a cell cycle, is returning back to the initial state. The bifurcation analysis for the mutants could be used uncovering the role of proteins in the cell cycle regulation network.

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Parallelization of Cell Contour Line Extraction Algorithm (세포 외곽선 추출 알고리즘의 병렬화)

  • Lee, Ho Seok;Yu, Suk Hyun;Kwon, Hee Yong
    • Journal of Korea Multimedia Society
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    • v.18 no.10
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    • pp.1180-1188
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    • 2015
  • In this paper, a parallel cell contour line extraction algorithm using CUDA, which has no inner contour lines, is proposed. The contour of a cell is very important in a cell image analysis. It could be obtained by a conventional serial contour tracing algorithm or parallel morphology operation. However, the cell image has various damages in acquisition or dyeing process. They could be turn into several inner contours, which make a cell image analysis difficult. The proposed algorithm introduces a min-max coordinates table into each CUDA thread block, and removes the inner contour in parallel. It is 4.1 to 7.6 times faster than a conventional serial contour tracing algorithm.

A QoS-Guaranteed Cell Selection Strategy for Heterogeneous Cellular Systems

  • Guo, Qiang;Xu, Xianghua;Zhu, Jie;Zhang, Haibin
    • ETRI Journal
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    • v.28 no.1
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    • pp.77-83
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    • 2006
  • In order to improve the accuracy of cell selection in heterogeneous cellular systems, this paper proposes a fuzzy multiple-objective decision-based cell selection (FMDCS) strategy. Since heterogeneous cellular systems have different access technologies and multiple traffic classes, the strategy adopts cell type, data rate, coverage, transmission delay, and call arrival rate as evaluation indices, and uses different weight vectors according to the traffic classes of the mobile host. Then, a fuzzy multiple-objective decision algorithm is applied to select the optimal cell from all candidates. This paper also gives an instance analysis and simulation. The instance analysis shows FMDCS makes different selections for different traffic classes. Simulation results of the after-handoff quality-of-service (QoS) show the selected cell can provide MH optimal service.

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Bifurcation analysis of budding yeast cell cycle

  • Nguyen, Cuong;Yoon, Chang-No;Kim, Hak-Yong;Han, Seung-Kee
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2004.11a
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    • pp.50-56
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    • 2004
  • Bifurcation analysis of cell cycle regulation in the budding yeast is performed basedon the mathematical model by Chen et al [Molecular biology of cell, 11:369-391, 2000]. On the bifurcation diagram, locations of both stable and unstable solutions of the nonlinear differential equations are presented by taking the mass of cell as a controlparameter. Based on the bifurcation diagram, dynamic mechanism underlying the 'start' transition, initiation of a new round of cell cycle, and the 'finish' transition, completion of cell cycle and returning back to the initial state, is discussed: the 'start' transition is a transition from a stable fixed solution for a small mass and to an oscillatory state for a large mass, and the 'finish' transition is a switching back to the stable fixed solution from the oscillatory state. To understand the role of the genes during the cell cycle regulation, bifurcation diagrams for the mutants are compared with that of the wild type.

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Mechanical/Biochemical Analysis of Cell Adhesion Strengthening (세포흡착 거동의 기계적/생화학적 분석)

  • Shin, Heung-Soo
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.1455-1457
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    • 2008
  • Cell adhesion is a coordinated process involving initial binding of integrin receptors to extracellular matrix (ECM), recruitment of adhesion proteins, and focal adhesion assembly. The formation of mechanically stable focal adhesion assembly of cells within surrounding ECM is a key parameter to direct numerous cellular functions including cell migration, differentiation, and apotosis. With current cell adhesion assays, it is difficult to understand contributions of each coordinated event on evolution of cell adhesion strengthening since cells spontaneously spread upon their adhesion to the substrate, thus remodeling their cytoskeletal structure. In this presentation, novel approaches for analysis of cell adhesion strengthening process based on the combination of mechanical device, micro-patterned substrates, and molecular biological techniques will be discussed.

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Flow analysis of the Hydrogen Recirculation System for Fuel Cells (연료전지 수소 재순환 시스템의 유동해석)

  • Kim, Jae-Choon;Lee, Yong-Taek;Chung, Jin-Taek;Kim, Yong-Chan;Hwang, In-Chul
    • 유체기계공업학회:학술대회논문집
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    • 2005.12a
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    • pp.759-764
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    • 2005
  • In this paper, numerical analysis of hydrogen recycle system has been conducted in order to enhance the efficiency of automotive fuel cell. Generally, the excess hydrogen is provided in the automotive fuel cell. Since the non-reaction hydrogen reduces automotive fuel cell efficiency, reuse of the non-reaction hydrogen can be helpful to improve the fuel cell performance. In case of PEM FC, the water vapor is provided to hydrogen from the cathode so that the mixture experiences phase change depending on the changes of pressure and temperature. The internal flow of the mixture in the hydrogen recirculation system of fuel cell was investigated for real flow conditions. The variation of performance, properties and mass fractions of mixture, hydrogen and water-vapor were investigated. This study was performed based on 80KW level automotive fuel cell's recycling system.

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Research on the Indices for Demonstrating Cell Conditions

  • Kim, Ik-Hyun;Pan, Sung-Bum
    • Journal of Sensor Science and Technology
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    • v.21 no.5
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    • pp.324-328
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    • 2012
  • In the past a few decades, various kinds of cells have been examined in laboratories all over the world, and their interesting results have been expressed through various methods in journal publications. For a representative example, the increment or reduction of cell numbers during a bio-related experimental process has been demonstrated using the hazard ratio in survival analysis or in the form of a graph. In addition, the condition of cells such as their normality or abnormality would be indicated by the images of the cell nuclei or membranes treated with proper fluorescent labeling. However, the above methods seem to not be quantitative but rather qualitative assessments, which might be difficult to provide people with the eidetic understanding through parameters or numerical data. With adequate suggestions on any indices enabling the explanation for cell conditions, some analyses may be underestimated due to the lack of objectiveness caused by merely linguistic evaluation for the cell conditions, not numerally scientific interpretation. Therefore, in this study, we would suggest some indices enabling quantitative analysis on the cellular conditions.

Three-Dimensional Fluid Flow Analysis of Photoacoustic Spectroscopy Cell for Measurement of Automotive Exhaust Gas (자동차 배출가스 측정을 위한 Photoacoustic Spectroscopy Cell의 3차원 유동장 해석)

  • 김현철;박종호
    • Transactions of the Korean Society of Automotive Engineers
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    • v.11 no.2
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    • pp.111-118
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    • 2003
  • Recently, environmental damage to urban area becomes serious problem due to the exhaust emissions by increasing the number of vehicle. Especially, exhaust emission from diesel vehicles are blown to be harmful to human health and environment. Photoacoustic Spectroscopy system is very useful technology for simultaneous and continuous measurement of the various components of the automotive exhaust gas. In this study, in order to reduce emission gases from automobile, we tried to develop the measurement system of Photoacoustic Spectroscopy. To improve performance of high sensitive Photoacoustic Spectroscopy system for automotive exhaust emissions, the shape of Photoacoustic Spectroscopy cell was optimized to use the flow analysis. And Exhaust emission data of the 1,500cc gasoline engine was fixed the working fluid. The characteristics of fluid flow for cell were analyzed by various conditions in detail.