• Title/Summary/Keyword: Cell Type

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Evaluation of Driving Properties by Cell-gap Difference of Single Particle-Microcapsule Type Electronic Paper (싱글입자-마이크로캡슐형 전자종이의 셀갭 차이에 따른 구동 특성평가)

  • Song, Jin-Seok;Kim, Young-Cho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.28 no.8
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    • pp.518-523
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    • 2015
  • We fabricate a single particle-microcapsule type electronic paper using electrophoresis, which is different with a reported dual particle-microcapsule type and of which electro-optical researches are not reported. So we analyzed a basic properties, such as reflectivity, response time, and driving voltage. Our display panels having various cell-gaps of $30{\mu}m$, $34{\mu}m$, $38{\mu}m$, $42{\mu}m$, and $46{\mu}m$ are inspected. As a results, a driving voltage is defined to 10 V and desirable cell-gap is $30{\mu}m$ or $34{\mu}m$. Considering a mechanical strength, the optimum cell-gap is $34{\mu}m$ for the single particle type electronic paper.

Discharge Properties of an AC Plasma Display Panel with Comb-Type Electrodes (Comb형 전극구조를 갖는 AC 플라즈마 디스플레이 패널의 방전특성)

  • Kim, Dong-Su;Jang, Ji-Geun;Im, Seong-Gyu;Jang, Ho-Jeong
    • Korean Journal of Materials Research
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    • v.9 no.2
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    • pp.195-198
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    • 1999
  • The newly designed Ac-PDP(plasma display panel with comb-type electrode) structure was fabricated by using the screen printing method and the electrical and optical characteristics were measured under the various discharge conditions. The minimum firing voltages measured under pure Ne and Ne+Xe mixture gas with the application of 10 kHz square wave were 190V and 160V, respectively. The firing voltages of the PDP cell with the comb-type electrode were compared with those of the cell with matrix electrode under the same discharge condition. The firing voltage of the PDP cell with comb-type electrode was 15 V lower than that of the PDP cell with conventional matrix electrodes.

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Primary Renal Cell Tumors in Four Nonhuman Primates (영장류의 신장종양 발생 4례)

  • Park, Jun-Won;Jung, Iruo;Jee, Hyang;Yoo, Mi-Jin;Kim, Dae-Yong;Shin, Nam-Shik
    • Journal of Veterinary Clinics
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    • v.26 no.5
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    • pp.508-510
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    • 2009
  • Primary renal cell tumors were described in four nonhuman primates (Erythrocebus patas, Macaca cyclopis, Mandrillus sphinx, and Macaca fascicularis) that have been kept for exhibition at Seoul Zoo. Histologically, all of them were renal adenoma. Each one was clear cell type and tubular type, respectively. The rest two were papillary type adenoma. Clear cell type adenoma was bilaterally affected.

한국산 산개구리 (Rana dybowskii Gruenther)의 뇌하수체에 관한 연구: II. 활동기와 동면기의 미세구조 비교

  • 김창환;김우갑;한성식;김지현
    • The Korean Journal of Zoology
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    • v.24 no.1
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    • pp.38-57
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    • 1981
  • Cardell, Jr. (1964)는 도룡뇽의 뇌하수체 전염에서 5가지의 분비세포를 구분하였으며 Dent와 Gupta (1967), 그리고 Iturrza (1964)는 영원류에서 5가지 분비세포를 구분하여 보고한 바 있다. 또 Doerr-Schott (1965)는 개구리에서 5가지 분비세포를, Mira-Moser (1969, 1970)는 6가지의 분비세포와 한가지의 무과립세포를 구분하였다. Shinkawa등 (1972)도 역시 7가지 cell type을 구분하였다. Shinkawa와 Nakai (1972)는 참개구리에서 역시 7가지 cell type을, 그리고 이들이 선정한 3 cell type에서 ACTH를 분비한다는 사실을 보고 하였다. 이에 본 연구자들은 산개구리를 재료로 하여 우선 동면기의 것을 실험하였던 바 7가지 cell type을 구분한 바 있고, 다시 활동기의 것을 재료로하여 세포내 소기관의 변화를 관찰하였는데 여기서 몇가지 차이점을 보고하는 바이다.

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The role of cell type-specific mitochondrial dysfunction in the pathogenesis of Alzheimer's disease

  • Kim, Dong Kyu;MookJung, Inhee
    • BMB Reports
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    • v.52 no.12
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    • pp.679-688
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    • 2019
  • The decrease of metabolism in the brain has been observed as the important lesions of Alzheimer's disease (AD) from the early stages of diagnosis. The cumulative evidence has reported that the failure of mitochondria, an organelle involved in diverse biological processes as well as energy production, maybe the cause or effect of the pathogenesis of AD. Both amyloid and tau pathologies have an impact upon mitochondria through physical interaction or indirect signaling pathways, resulting in the disruption of mitochondrial function and dynamics which can trigger AD. In addition, mitochondria are involved in different biological processes depending on the specific functions of each cell type in the brain. Thus, it is necessary to understand mitochondrial dysfunction as part of the pathological phenotypes of AD according to each cell type. In this review, we summarize that 1) the effects of AD pathology inducing mitochondrial dysfunction and 2) the contribution of mitochondrial dysfunction in each cell type to AD pathogenesis.

Ammonium Ion Effects and Its In Situ Removal by Using Immobilized Adsorbent in Hybridoma Cell Culture (하이브리도마 세포배양에서 암모늄 이온의 영향 및 고정화 흡착제에 의한 암모늄 이온의 동시제거)

  • 정연호;이해익
    • KSBB Journal
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    • v.11 no.3
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    • pp.329-339
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    • 1996
  • The effects of ammonium ion on cell growth kinetics, monoclonal antibody productivity, and cell metabolism of hybridoma cells were investigated. The mouse-mouse hybridoma cell line VlIIH-8 producing mouse IgG2a was used as a model system. Ammonium ion showed an inhibitory effect on cell growth and monoclonal antibody production. New immobilized adsorbents were developed for the reduction of the inhibitory effect of ammonium ion. The ammonium ion selective zeolite, Phillipsite-Gismondine was entrapped in calcium alginate bead or in dialysis membrane and applied to the hybridoma cell culture system for the in situ removal of ammonium ion from culture media. The effects of ammonium the both serum supplemented and serum free media on the cell growth were studied by applying immobilized adsorbents of calcium alginate bead type. The results demonstrated a substantial enhancement in cell growth. Applying immobilized adsorbents of dialysis membrane type to serum supplemented media also resulted in the stimulation of cell growth, cell viability and monoclonal antibody production.

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Transgenic tobacco plants overexpressing the Nicta; CycD3; 4 gene demonstrate accelerated growth rates

  • Guo, Jia;Wang, Myeong-Hyeon
    • BMB Reports
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    • v.41 no.7
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    • pp.542-547
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    • 2008
  • D-type cyclins control the onset of cell division and the response to extracellular signals during the G1 phase. In this study, we transformed a D-type cyclin gene, Nicta;CycD3;4, from Nicotiana tabacum using an Agrobacterium-mediated method. A predicted 1.1 kb cyclin gene was present in all of the transgenic plants, but not in wild-type. Northern analyses showed that the expression level of the Nicta;CycD3;4 gene in all of the transgenic plants was strong when compared to the wild-type plants, suggesting that Nicta;CycD3;4 gene driven by the CaMV 35S promoter was being overexpressed. Our results revealed that transgenic plants overexpressing Nicta;CycD3;4 had an accelerated growth rate when compared to wild-type plants, and that the transgenic plants exhibited a smaller cell size and a decreased cell population in young leaves when compared to wild-type plants.

Development of the Pin Type Load-cell Using Strain Gauge (Strain Gauge를 이용한 핀형 로드셀 개발)

  • Lee, Dong-Wook;Park, Min-Hyuk;Lee, Gye-Gaong;Kim, In-Hwan;Lee, Seok-Soon
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.13 no.4
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    • pp.75-82
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    • 2014
  • A pin-type load-cell which uses shear-type strain gauges was developed to measure the tension of a wire in a winch. A finite element analysis was performed to determine the locations of the strain gauges. All of the shear-type strain gauges were attached onto parts that undergo regularly shear stress distributions. A Wheatstone bridge circuit was used to connect each of the gauges and to measure the strains. Linearity within the 5% error range was noted when testing the pin-type load-cell.

NADPH oxidase inhibitor diphenyleneiodonium induces p53 expression and cell cycle arrest in several cancer cell lines (NADPH oxidase 저해제인 diphenyleneiodonium의 p53 발현 및 암세포의 성장억제에 대한 연구)

  • Jo, Hong-Jae;Kim, Kang-Mi;Song, Ju-Dong;Park, Young-Chul
    • Journal of Life Science
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    • v.17 no.6 s.86
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    • pp.778-782
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    • 2007
  • The Diphenyleneiodonium (DPI) is widely used as an inhibitor of flavoenzymes, particularly NADPH oxidase. In this study, we investigated the effect of DPI on the cell growth progression of human colon cancer cells HCT-116 (wild-type p53), HT-29 (p53 mutant) and human breast cancer cells MCF-7 (wild-type p53). DPI treatment in cancer cells evoked a dose- and time-dependent growth inhibition, and also induced the cell cycle arrest in C2/M phase. The peak of cell population arrested in C2/M phase was observed at12 hr after treatment of DPI. In addition, DPI significantly induced the expression of p53, which induces proapoptotic genes in response to DNA damage or irreparable cell cycle arrest, at 6 hr in DPI-stimulated cells. However, a catechol apocynin, which inhibits the assembly of NADPH oxidase, did not induce p53 expression. This suggest that p53 expression induced by DPI is not associated with the inhibition of NADPH oxidase. In conclusion, we suggest that DPI induces the expression of wild-type p53 by ROS-in-dependent mechanism in several cancer cells, and upregulated p53 may be involved in regulatory mechanisms for growth inhibition and cell cycle arrest at C2/M phase in DPI-stimulated cells.

Power Output in Various Types of Solar Panels in the Central Region of Korea (한국 중부 지역의 태양광 모듈 타입에 따른 발전량 특성)

  • Chang, Hyo Sik
    • Journal of the Korean Solar Energy Society
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    • v.38 no.1
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    • pp.37-44
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    • 2018
  • Solar panels are modules made up of many cells, like the N-type monosilicon, P-type monosilicon, P-type multisilicon, amorphous thin-film silicon, and CIGS solar cells. An efficient photovoltaic (PV) power is important to use to determine what kind of cell types are used because residential solar systems receive attention. In this study, we used 3-type solar panels - such as N-type monosilicon, P-type monosilicon, and CIGS solar cells - to investigate what kind of solar panel on a house or building performs the best. PV systems were composed of 3-type solar panels on the roof with each ~1.8 kW nominal power. N-type monosilicon solar panel resulted in the best power generation when monitored. Capacity Utilization Factor (CUF) and Performance Ratio (PR) of the N-type Si solar panel were 14.6% and 75% respectively. In comparison, N-type monosilicon and CIGS solar panels showed higher performance in power generation than P-type monosilicon solar power with increasing solar irradiance.