• Advances in biomechanics and applications
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• 제1권1호
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• pp.41-55
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• 2014

Acellular intra-myocardial biomaterial injections have been shown to be therapeutically beneficial in inhibiting ventricular remodelling of myocardial infarction (MI). Based on a biventricular canine cardiac geometry, various finite element models were developed that comprised an ischemic (II) or scarred infarct (SDI) in left ventricular (LV) antero-apical region, without and with intra-myocardial biomaterial injectate in layered (L) and bulk (B) distribution. Changes in myocardial properties and LV geometry were implemented corresponding to infarct stage (tissue softening vs. stiffening, infarct thinning, and cavity dilation) and injectate (infarct thickening). The layered and bulk injectate increased ejection fraction of the infarcted LV by 77% (II+L) and 25% (II+B) at the ischemic stage and by 61% (SDI+L) and 63% (SDI+B) at the remodelling stage. The injectates decreased the mean end-systolic myofibre stress in the infarct by 99% (II+L), 97% (II+B), 70% (SDI+L) and 36% (SDI+B). The bulk injectate was slightly more effective in improving LV function at the remodelling stage whereas the layered injectate was superior in functional improvement at ischemic stage and in reduction of wall stress at ischemic and remodelling stage. These findings may stimulate and guide further research towards tailoring acellular biomaterial injectate therapies for MI.

• Journal of Chest Surgery
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• 제54권1호
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• pp.59-64
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• 2021

Background: Diaphragmatic injuries following blunt or penetrating thoraco-abdominal trauma are rare, but can be life-threatening. Rib fractures are the most common associated injury in patients with a traumatic diaphragmatic injury (TDI). We hypothesized that the pattern of rib fracture injuries could dictate the likelihood of acute TDIs. Methods: A retrospective study was carried out between April 2014 and October 2018 to analyze patients with TDIs and rib fractures at a major trauma center in London, United Kingdom. Results: Over the study period, 1,560 patients had rib fractures, of whom 14 had associated diaphragmatic injuries. Left-sided diaphragmatic injuries were found in 8 patients (57%). A significant proportion of the rib fractures were located posterolaterally (44.9%). The highest frequency of fractures was found in ribs 5-10, which accounted for 74% of all the fractures. Ten patients underwent surgery, of whom 7 were diagnosed with a diaphragmatic injury intraoperatively after video-assisted thoracoscopic surgery assessment of the pleural cavity. Two patients died due to severe injuries of other organs and the remaining 2 patients were managed conservatively. Conclusion: Our series of patients demonstrates a relationship between significant rib fractures and diaphragmatic injuries in trauma patients, and the diagnostic difficulties in identifying the condition. We found that the location of the rib fractures and the pattern of injury in patients with TDIs were much lower and posterolateral in the chest wall without a preference for laterality. We suggest using a thoracoscope in patients undergoing chest wall surgery post-trauma to aid in diagnosing this condition.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제35권2호
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• pp.88-93
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• 2013

Purpose: Maxillary sinus elevation has been widely used to enable insertion of endosseous implants in severely resorbed maxilla. Maxillary sinusitis after this procedure was considered to be the major drawback, therefore, preoperative evaluation of paranasal sinus is considered to be important. In order to evaluate the condition of the sinus, we used Waters' projection. In this study, asymptomatic patients were evaluated by Waters' view, and compared to timing to assess the sinus cavity. Methods: The retrospective study was based on 14 patients who were performed sinus elevation surgery in Seoul National University Dental Hospital. These patients did not show any signs of maxillary sinusitis. These patients were taken Waters' view at preoperative, postoperative 1 day, 3 months, 6 months. In Waters' view, presence of air fluid level, radiopacity of sinus wall, or radiopacity of entire maxillary sinus were evaluated. The density, and sinus dimension changes were assessed using Adobe Photoshop CS5$^{(R)}$ (Adobe Systems Inc., San Jose, CA, USA). Results: Findings of Waters views in patients with clear maxillary sinus at preoperative time were followed by elevated sinus floor with transplanted bone, mucosal swelling, and air fluid level. At postoperative 3 months, and 6 months, the radiographic findings were similar to preoperative state. By contrast, patients with preoperative mucosal swelling, or haziness in sinus cavity showed radiopacity entire sinus in Waters' view. In cases of the patients who were treated with simultaneous treatment to mucosal swelling, good status of sinus cavity were found. Conclusion: Although Waters' projections provide the limited information, and is less sensitive method compared with computed tomography, it is simple, easy, and economical method to assess of maxillary sinus. We suggest using Waters' view as radiographic routine tool for evaluation of sinus condition, especially in the sinus elevation surgery.

• Korean Chemical Engineering Research
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• 제49권1호
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• pp.47-55
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• 2011

K사의 고무 사출성형에 있어서 애로사항인 등속조인트 부트(boots)의 크 (crack) 발생 등의 문제점을 해결하기 위하여, 상용 CAE 프로그램인 MOLDFLOW(Ver. 5.2)를 이용한 전산모사를 수행하여 적정금형설계를 도출하고 적정작업조건을 구축하였다. 그 결과 크 의 발생 원인은 크 이 발생하는 위치에 형성되는 weld 및 meld line의 형성 때문이고, 또한 크 이 발생하는 위치에서의 가류(curing)가 불완전한 것이 확인되었다. 이와 같은 weld 및 meld line의 형성을 방지하기 위해서 게이트(gate)의 위치를 변경하고 최적위치에 설계함으로써, 유동선단(melt front)의 충돌 또는 수지흐름의 만남을 최소화하는 충전패턴(fill pattern)을 형성하고 부트 안쪽 하단의 크 발생을 방지하였다. Weld 및 meld line과 에어트랩(air trap) 불량이 가장 큰 게이트 위치는 각각 최적 게이트위치를 기준으로 서로 정반대 방향임이 관찰 되었다. 한편 몰드(mold)의 온도를 $170^{\circ}C$로 유지하게 함으로써 크 이 발생했던 위치에 가류조건을 만족시켰다.

• 대한소아치과학회지
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• 제38권4호
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• pp.376-382
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• 2011

제1대구치는 막중한 역할을 함에도 불구하고, 청소년 이전에 건강을 상실하는 경우가 드물지 않다. 본 연구는 청소년기 이전에 치수치료를 받게 된 제1대구치의 우식 및 수복 상태와 분포를 파악할 목적으로 시도되었다. 최근 5년간 부산대학교 치과병원에서 치수치료를 받은 18세 이하 106명 환자의 135개 제1대구치를 대상으로 의무기록에 대한 조사를 시행하여 다음과 같은 결과를 얻었다. 1. 평균 연령은 11.9세(남 11.5세, 여 12.5세)였고 유의한 성차를 보였으며(p<0.05), 악별로는 상악 47개, 하악 88개로 하악 치아가 더 많았다. 2. 치수 치료 전 치료 기왕력이 없는 치아는 74개, 치수 또는 수복 치료를 받은 치아는 61개였다. 그 중 재치수치료를 받게 된 경우는 22개로 치수절제술-치수절단술의 순이었으며, 단순 수복치료를 받았던 치아는 39개로 복합레진-아말감-GI-인레이-수복물 탈락 후 미치료-열구전색 및 주조 전장관의 순이었다. 3. 병소 위치가 분류 가능한 73개의 병소 중에서는 근심면 병소가 22개, 교합면 혹은 협설면 병소 39개, 원심면 병소가 12개를 차지하였다.

• 치위생과학회지
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• 제17권2호
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• pp.116-122
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• 2017

본 연구는 QLF-D를 이용하여 와동 내벽에 형성된 초기 이차우식증을 탐지가 가능한지 평가해보고, 표면에서 관찰한 우식병소와 실제 와동 내벽에 발생한 병소 간에 차이가 있는지 확인해보고자 시행하였으며, 다음과 같은 결과를 얻었다. 시간의 흐름에 따라 시편의 표면에서 관찰되는 이차우식병소가 점점 진행되었다. 수복물 변연의 우식병소 부분이 수복물에 가려지거나 형광에 의해 우식부분을 육안으로 판단하기에 어려운 부분들이 보였으며, 수복물이 있는 경우의 ${\Delta}F$값은 $-14.20{\pm}3.24$, 와동만 있는 경우의 ${\Delta}F$값은 $-11.56{\pm}3.94$ 로 수복물이 있는 경우의 ${\Delta}F$값이 유의하게 높게 나타났다(p<0.001). 또한 수복한 표면에서 측정한 병소의 ${\Delta}F$값은 $-14.20{\pm}3.24$, 횡단면에서 측정한 병소의 ${\Delta}F$값은 $-18.64{\pm}3.75$로 횡단면보다 표면에서 측정한 병소의 ${\Delta}F$값이 약 1.31배 가량 유의하게 크게 나타났으며, correlation은 0.026으로 낮게 나타났다(p<0.001). 하지만 수복하지 않은 표면과 횡단면의 ${\Delta}F$값 간의 correlation값은 0.613으로 높게 나타났다. 이를 통해 QLF-D를 이용하여 표면에서도 이차우식병소의 탐지가 가능하다는 것을 알 수 있었다. 다만, 수복물에 의한 간섭이 있을 수 있고, 병소의 특성상 실제 병소의 심도보다 적게 측정될 수 있으므로 이에 대한 고려를 통한 탐지가 이루어져야 할 것이다.

• 한국전산유체공학회지
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• 제15권2호
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• pp.86-94
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• 2010

A thermal-hydraulic code, named CUPID, has been developed for the analysis of transient two-phase flows in nuclear reactor components. A two-fluid three-field model was used for steam-water two-phase flows. To obtain numerical solutions, the finite volume method was applied over unstructured cell-centered meshes. In steam-water two-phase flows, a phase change, i.e., evaporation or condensation, results in a great change in the flow field because of substantial density difference between liquid and vapor phases. Thus, two-phase flows are very sensitive to the local pressure distribution that determines the phase change. This in turn puts emphasis on the accurate evaluation of local pressure gradient. This paper presents a new reconstruction method to evaluate the pressure gradient at cell centers on unstructured meshes. The results of the new scheme for a simple test function, a gravity-driven cavity, and a wall boiling two-phase flow are compared with those of the previous schemes in the CUPID code.

• International Journal of Fluid Machinery and Systems
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• 제3권2호
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• pp.122-128
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• 2010

The attachment of inducer in front of main impeller is a powerful method to improve cavitation performance; however, cavitation surge oscillation with low frequency occurs with blade cavity growing to each throat section of blade passage simultaneously. Then, one conceptual method of installing suction axi-asymmetrical plate has been proposed so as to keep every throat passage away from being unstable at once, and the effect on suppression of the oscillation were investigated. In the present study, cavitation behaviors in the inducer is observed with distributing multi-cameras circumferentially, recording simultaneously and reconstructing multi-photos on one plane field as moving a linear cascade. Observed results are utilized for discussion with other measuring results as casing wall pressure distribution. Then the suppression mechanism of oscillation by installing axi-asymmetrical inlet plate will be clarified in more details.

• Applied Microscopy
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• 제18권2호
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• pp.91-101
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• 1988

The ultrastructure of the sac and tail portion of the large ampullate gland and production of the silk materials in the orb web spider, Nephila clavata L. Koch, are studied with electron microscope. Large ampullate glands, the largest glands among the seven kinds of silk glands in this species, are composed of three parts which are the excretory duct, the storage sac and the convoluted tail. The wall of the sac is composed of a single layer of columnar epithelial cells. In the cytoplasm of these cells several kinds of the secretory granules, which are commonly associated with the rough endoplasmic reticula and had characteristic crystalloid, are seen. According to the morphology and internal textures of these granules, the sac portion is subdivided into proximal(connected with the convoluted tail) and distal(connected with excretory duct) portion. Between these two portions, the proximal portion is longer than the distal by four times. Silk materials, being synthesized to the shape of secretory granules, within the glandular epithelial cell of the tail portion are released to the inner cavity by the mechanism of the eccrine secretion. These secretory granules are originated from the rough endoplasmic reticula of the glandular epithelial cells, whereas no Golgi complexes has been found in any of the cells which have been examined.

• 한국항공우주학회지
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• 제34권12호
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• pp.18-24
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• 2006

슬롯과 다공판을 이용한 충격파와 난류 경계층 간섭유동의 피동제어에 관한 연구가 수행되었다. 슬롯의 다양한 형상 변화가 간섭유동에 미치는 영향이 관찰되었으며, 이를 위하여 간섭유동 후방에서 피토/벽압력 분포 및 쉴리렌, 유맥선, 오일막 간섭 줄무늬 형상과 같은 유동가시화 결과 등이 얻어졌다. 유동방향의 슬롯의 경우 간섭유동 후방에서 제어되지 않은 경우와 비교하여 보다 높은 피토압력이 국소적으로 관찰되었으나, 폭방향 슬롯제어는 전체적으로 제어되지 않은 경우에 비하여 피토압력 크기에서 큰 장점을 보이지 않았다.