• Wind and Structures
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• v.38 no.3
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• pp.193-202
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• 2024

Modern high-rise tower designs incorporating recessed balcony cavity spaces can be prone to high-frequency and narrow-band Rossiter aerodynamic excitations under glancing incident winds that can harmonize and compete with recessed balcony volume acoustic Helmholtz modes and facade elastic responses. Resulting resonant inertial wind loading to balcony facades responding to these excitations is additive to the peak design wind pressures currently allowed for in wind codes and can present as excessive facade vibrations and sub-audible throbbing in the serviceability range of wind speeds. This paper presents a methodology to determine Cavity Amplification Factors to account for façade resonant inertial wind loads resulting from balcony cavity aero-acoustic-elastic resonances by drawing upon field observations and the results of full-scale monitoring and model-scale wind tunnel tests. Recessed balcony cavities with single orifice type openings and located within curved façade tower geometries appear particularly prone. A Cavity Amplification Factor of 1.8 is calculated in one example representing almost a doubling of local façade design wind pressures. Balcony façade and tower design recommendations to mitigate wind induced aero-acoustic-elastic resonances are provided.

• Journal of Korean Society for Atmospheric Environment
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• v.9 no.4
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• pp.295-302
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• 1993

The nature of the cavity region and dispersion around trianglular ridge was investigated using model. The artifical neutral boundary layer was simulated in water channel. Two dimensional trianglar ridges, having height of 1.2 cm and various width were placed normal to the flow. Mean velocity with many dimensionless parameters were measured and compared with wind tunnel results by other studies. Using vorticity generator and roughness, the neutral boundary layer was well represented by the water channel. concentration patterns resulting from dye source placed 0.2 cm height above were examined. Narrower the trianglar ridge width resulted in increased amplification factor and the larges amplification factor was observed near downward top of the ridge.

• International Journal of Aeronautical and Space Sciences
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• v.7 no.2
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• pp.26-32
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• 2006

This paper targets a direct and quantitative prediction of characteristics of unstable waves in a combustion chamber, which employs the governing equations derived in terms of amplification factors of flow variables. A freshly formulated nonlinear acoustic equation is obtained and the analysis of unsteady waves in a rocket engine is attempted. In the present formalism, perturbation method decomposes the variables into time-averaged part that can be obtained easily and accurately and time-varying part which is assumed to be harmonic. Excluding the use of conventional spatially sinusoidal eigenfunctions, a direct numerical solution of wave equation replaces the initial spatial distribution of standing waves and forms the nonlinear space-averaged terms. Amplification factor is also calculated independently by the time rate of changes of fluctuating variables, and is no longer an explicit function for compulsory representation. Employing only the numerical computation, major assumptions inevitably inherent, and in erroneous manner, in up to date analytical methods could be avoided. With two definitions of amplification factor, 1-D stable wave and 3-D unstable wave are examined, and clearly demonstrated the potentiality of a suggested theoretical-numerical method of combustion instability.

• Journal of Chest Surgery
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• v.43 no.6
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• pp.588-595
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• 2010

Background: Base on types of tumor, the types of expressed tumor is diverse and the difference in its expression rate is even more various. Due to such reasons an animal model is absolutely needed for a clinical research of lung cancer. The author attempted oncogenesis by cultivating a cell line of non-small cell carcinoma and then injecting it inside thoracic cavities of nude mice. The author conducted quantitative analyses of HER2/neu tumor gene - an epidermal growth factor receptor (EGFR) related to lung cancer, and TGF-${\beta}_1$, which acts as a resistance to cell growth inhibition and malignant degeneration. In order to investigate achievability of the oncogenesis, histological changes and the expression of cancer gene in case of orthotopic lung cancer is necessary. Material and Method: Among 20 immunity-free male BALB/c, five nude mice were selected as the control group and rest as the experimental group. Their weights ranged from 20 to 25 gm (Orient, Japan). After injection of lung cancer line (SW900 G IV) into the pleural cavity of nude mice, They were raised at aseptic room for 8 weeks. HER2/neu was quantitatively analyzed by separating serum from gathered blood via chemiluminiscent immunoassay (CLIA), and immunosandwitch method was applied to quantitatively analyze TGF-${\beta}_1$. SPSS statistical program (SPSS Version 10.0, USA) was implemented for statistical analysis. Student T test was done, and cases in which p-value is less than 0.05 were considered significant. Result: Even after lung cancer was formed in the normal control group or after intentionally injected lung cancer cell line, no amplification of HER2/neu gene showed reaction. However, the exact quantity of TGF-${\beta}_1$ was $28,490{\pm}8,549pg/mL$, and the quantity in the group injected with lung cancer cell was $42,362{\pm}14,449pg/mL$, meaning 1.48 times highly Significant (p<0.483). It proved that HER2/neu gene TGF-${\beta}_1$ had no meaningful interconnection. Conclusion: TGF-${\beta}_1$ gene expressed approximately 1.48 times amplification in comparison to the control group. The amplification of TGF-${\beta}_1$ meant somatic recuperation inhibition mechanism due to carcinogenesis in nude mice was definitely working. It may be implemented as a quantitative analysis that allows early detection of lung cancer in human body.