• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.22 no.4
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• pp.303-329
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• 2019

Intestinal failure (IF) is the critical reduction of the gut mass or its function below the minimum needed to absorb nutrients and fluids required for adequate growth in children. Severe IF requires parenteral nutrition (PN). Pediatric IF is most commonly due to congenital or neonatal intestinal diseases or malformations divided into 3 groups: 1) reduced intestinal length and consequently reduced absorptive surface, such as in short bowel syndrome (SBS) or extensive aganglionosis; 2) abnormal development of the intestinal mucosa such as congenital diseases of enterocyte development; 3) extensive motility dysfunction such as chronic intestinal pseudo-obstruction syndromes. The leading cause of IF in childhood is the SBS. In clinical practice the degree of IF may be indirectly measured by the level of PN required for normal or catch up growth. Other indicators such as serum citrulline have not proven to be highly reliable prognostic factors in children. The last decades have allowed the development of highly sophisticated nutrient solutions consisting of optimal combinations of macronutrients and micronutrients as well as guidelines, promoting PN as a safe and efficient feeding technique. However, IF that requires long-term PN may be associated with various complications including infections, growth failure, metabolic disorders, and bone disease. IF Associated Liver Disease may be a limiting factor. However, changes in the global management of IF pediatric patients, especially since the setup of intestinal rehabilitation centres did change the prognosis thus limiting "nutritional failure" which is considered as a major indication for intestinal transplantation (ITx) or combined liver-ITx.

• Journal of Sasang Constitutional Medicine
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• v.17 no.3
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• pp.103-112
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• 2005

1. Objective : The present author have examined the comparative effects of Hyeongbangjihwang-tang and Sibimikwanjung-tang in glycerol-induced acute renal failure, a model for myoglobinuric acute renal failure. 2. Methods : Above two prescriptions were applied to rat ad libitum and serum level of creatinine, glucose and blood urea nitrogen(BUN) were measured. And serum level of $Na^+$, $K^+$ and $Cl^-$, too. 50%(vol/vol) glycerol at a dose of 10 ml/kg of rat body weight intramuscularly and 1% concentration of prescriptions were applied to rats for 7 days ad libitum. 3. Results : Serum level of creatinine and $K^+$ significantly increased by glycerol injection, and these showed pre-renal and renal cause of acute renal failure. Hyeongbangjihwang-tang administered group showed decreasing tendency on serum level of creatinine when compared with control groups, but not significant. Sibimikwanjung-tang administered group showed significant increase of serum level of BUN when compared with control groups. 4. Conclusions : Above two prescriptions showed no significant changes on glycerol induced acute renal failure, but Hyeongbangjihwang-tang and Sibimikwanjung-tang showed a little different manner of response.

• Journal of The Korean Society of Agricultural Engineers
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• v.56 no.1
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• pp.71-79
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• 2014

In this study, an experiment with large-scale model was performed according to raising the embankment in order to investigate the behavior of failure for embankment and spillway transitional zone due to overtopping. The pore water pressure, earth pressure, settlement and failure pattern by a rapid drawdown and overtopping were compared and analyzed. The pore water pressure and earth pressure at spillway transitional zone by overtopping increased a rapidly with the expansion of seepage erosion, but the crest showed a smally change due to effect of the inclined core type. And it is considered an useful data that can accurately estimate the possibility of failure of the reservoirs. A settlement at overtopping decreased a rapidly due to failure of crest. The relative settlement difference due to change of the water level at the upstream and downstream slope cause increase largely crack of crest. The behavior of failure by overtopping was gradually enlarged towards reservoirs crest from the bottom of the spillway transition zone, the inclined core after the raising the embankment was influenced significantly to prevent the seepage erosion.

• International Journal of Quality Innovation
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• v.8 no.1
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• pp.137-153
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• 2007

Failure mode and effects analysis (FMEA) is a preventive technique in reliability management field. The successful implementation of FMEA technique can avoid or reduce the probability of system failure and achieve good product quality. The FMEA technique had applied in vest scopes which include aerospace, automatic, electronic, mechanic and service industry. The marking process is one of the back ends testing process that is the final process in semiconductor process. The marking process failure can cause bad final product quality and return although is not a primary process. So, how to improve the quality of marking process is one of important production job for semiconductor testing factory. This research firstly implements FMEA technique in laser marking process improvement on semiconductor testing factory and finds out which subsystem has priority failure risk. Secondly, a CCD position solution for priority failure risk subsystem is provided and evaluated. According analysis result, FMEA and CCD position implementation solution for laser marking process improvement can increase yield rate and reduce production cost. Implementation method of this research can provide semiconductor testing factory for reference in laser marking process improvement.

• Earthquakes and Structures
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• v.19 no.6
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• pp.471-484
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• 2020

Previous earthquakes show that, structural safety evaluations should include the evaluation of nonstructural components. Failure of nonstructural components can affect the operational capacity of critical facilities, such as hospitals and fire stations, which can cause an increase in number of deaths. Additionally, failure of nonstructural components may result in economic, architectural, and historical losses of community. Accelerations and random vibrations must be under the predefined limitations in structures with high technological equipment, data centers in this case. Failure of server equipment and anchored server racks are investigated in this study. A probabilistic study is completed for a low-rise rigid sample structure. The structure is investigated in two versions, (i) conventional fixed-based structure and (ii) with a base isolation system. Seismic hazard assessment is completed for the selected site. Monte Carlo simulations are generated with selected parameters. Uncertainties in both structural parameters and mechanical properties of isolation system are included in simulations. Anchorage failure and vibration failures are investigated. Different methods to generate fragility curves are used. The site-specific annual hazard curve is used to generate risk curves for two different structures. A risk matrix is proposed for the design of data centers. Results show that base isolation systems reduce the failure probability significantly in higher floors. It was also understood that, base isolation systems are highly sensitive to earthquake characteristics rather than variability in structural and mechanical properties, in terms of accelerations. Another outcome is that code-provided anchorage failure limitations are more vulnerable than the random vibration failure limitations of server equipment.

• Journal of Applied Reliability
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• v.10 no.2
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• pp.93-105
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• 2010

The following thesis provides an explanation for the definition of the MIL-HDBK-2155 : Failure Reporting, Analysis and Corrective Action System (FRACAS), which systemizes the collection and analysis of failure data and the feedback process of the results. It also presents a plan based on MIL-HDBK-2155 for the collection and analysis of operating specifications on weapon systems. The collection and analysis of failure data and the feedback process utilizing FRACAS contributes to identifying improvement requirements during equipment operation as well as finding and eliminating the root cause of the failures. The objective of applying FRACAS to weapon systems is to receive source data feedback for reliability enhancements and performance improvements during operation. This is done by recognizing weaknesses in the design or operation by identifying the type of failures that might occur, and by performing Failure Modes, Effects and Criticality Analysis(FMECA) and Failure Tree Analysis(FTA).

• Proceedings of the Korean Nuclear Society Conference
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• 1996.05b
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• pp.622-627
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• 1996

Detailed analysis of Feedwater Line Break (FLB) event for the fuel failure point of view are lack because the event was characterized as the increase in reactor coolant system (RCS) pressure. Up to now, the potential of the rapid system heatup case has been emphasized and comprehensively studied. The cooldown effects of FLB event is considered to be bounded by the Steam Line Break (SLB) event since the cooldown effect of SLB event is larger than that of the FLB event. This analysis provides a new possible path which can cause the fuel failure. The new path means that the fuel failure can occur under the heatup scenario because the Pressurizer Safety Valves (PSVs) open before the reactor trips. The 1000 MWe typical C-E plant FLB event assuming Loss of Offsite Power (LOOP) at the turbine trip has been analyzed as an example and the results show less than 1% of the fuel failure. The result is well within the acceptance criteria. In addition to that, a study was accomplished to prevent the fuel failure for the heatup scenario case as an example. It is found that giving the proper pressure gap between High Pressurizer Pressure Trip (HPPT) analysis setpoint and the minimum PSV opening pressure could prevent the fuel failure.

• Proceedings of the Korean Nuclear Society Conference
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• 2002.10a
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• pp.193.2-193
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• 2002

• Journal of the Korean Institute of Gas
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• v.22 no.3
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• pp.53-64
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• 2018

Natural gas is an explosive fluid and can cause severe human/material damage when buried high-pressure pipeline is failure, and there have been reported cases of considerable human life damage to actual buried pipeline failure. In domestic cases, the length and duration of pipeline operating are short due to rapid growth. Therefore, it is a fact that the establishment of effective accident data is insufficient for the cause of the accident. In order to systematically construct an accident database, the operation history of natural gas pipeline is longer than domestic, and the cause and frequency analysis of recent natural gas pipeline related accidents occurred in overseas major countries with a long pipeline network was conducted. Then, after grasping the trend of occurrence frequency by incident cause, we tried to establish the foundation for securing the stability of the domestic high-pressure gas transport pipeline network.

• Proceedings of the Korean Nuclear Society Conference
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• 2005.05a
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• pp.1313-1314
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• 2005