• Korean Journal of Clinical Pharmacy
• /
• v.20 no.1
• /
• pp.85-87
• /
• 2010

Recently, the prevalence of bladder cancer is increasing in the Korean society. As the risk factors of bladder carcinoma are variable, the early-stage diagnosis is regarded the best preventive practice. Hematuria is a specific sign of the malignancy as well as a kind of various medication-related adverse reactions. Some anti-coagulation therapy can cause bleedings including hematuria to the patients with cardiovascular diseases such as paroxysmal atrial fibrillation (PAF). Therefore, to the clinical pharmacists working in the anti-coagulation services (ACS), a closer monitoring of patients can give an opportunity to find certain ailments unexpectedly. In this case, a patient with PAF had episodes of sporadic hematuria in the course of warfarin therapy even though with its low levels of INR. An ACS pharmacist found a discrepancy between the bleeding symptoms and INR values, and recommended properly the patient to refer urologist. Fortunately, an early-stage of bladder carcinoma was found then followed by an excision performed to the lesion. Therefore, alert-minded and precise monitoring done by ACS pharmacist could optimize the therapeutic outcomes as well as increase the quality of life of the patient.

• Journal of the Korean Society of Safety
• /
• v.31 no.3
• /
• pp.28-33
• /
• 2016

Since defects in the wheels of railway vehicles, which occur due to wears with the rail, cause serious damage to the running device, the diagnostic monitoring system for condition-based maintenance is required to secure the driving safety. In this paper, we studied to apply a useful Cepstrum analysis to detect periodic structure in spectrum among the vibration signal processing techniques for the fault diagnosis of a rotating body such as wheel. In order to analyze in variations of train velocity, the Cepstrum analysis was performed after a domain change of the vibration signal from time domain to rotation angle domain. When domains change, it is important to use a interpolation for a uniform interval of the rotation angle. Finally, the Cepstrum analysis for wheel flat detection was verified by using the vibration signal including the disturbance resulting from the rail irregularities and the vibration of bogie components.

• Journal of Sensor Science and Technology
• /
• v.25 no.1
• /
• pp.35-40
• /
• 2016

Pulse diagnosis is one of the representative diagnostic methods in Oriental medicine. In this study, a pulse pressure sensor array coated with silicone, which includes 6 piezo-resistive sensors and 1 thermistor, is fabricated for pulse measurement. It is necessary to coat the pulse sensor array with silicone to avoid the fracture or damage of pressure sensors when the sensor is in contact with the skin and a constant pressure is applied. However, the silicone coating on the pulse sensor array can cause signal interference among the sensors in the pulse sensor array. The interference number (IN), a calculation for expressing the degree of interference among channels, is changed according to the silicone thickness on the pulse sensor array. The IN is increased by a thick silicone coating, but the fabrication error, an important index for the mass production of the sensor array, is reduced by the thickness of the silicone coating. We propose that the thickness of the silicone on the pulse sensor array is an important consideration for the performance of the fabricated sensor and manufacturing repeatability.

• Annals of Clinical Neurophysiology
• /
• v.9 no.2
• /
• pp.69-74
• /
• 2007

Electroencephalogram (EEG) is a representative diagnostic tool in epilepsy. However, there are several points of debate on the role of EEG in diagnosis and management of epilepsy. We suggest that EEG has some limitations for differential diagnosis from nonepileptic episodic diseases, classification of epilepsy, prediction of recurrence, and evaluation of treatment response. Interictal EEG cannot diagnose or exclude epilepsy because interictal epileptic discharge (IED) is frequently absent in epilepsy and can appear in nonepileptic conditions. Although EEG is helpful in classification of epilepsy, focal spikes in generalized epilepsy and secondary bilateral synchrony in localization related epilepsy cause interrater disagreement. It is controversial whether EEG predicts recurrence after the first seizure in adults. The predictive value of EEG in antiepileptic drug (AED) withdrawal is not absolute. The prognosis after AED withdrawal depends on epilepsy syndrome. Many studies could not confirm the value of EEG in assessing the treatment response. After all, epilepsy is clinically diagnosed and assessed. Interictal EEG alone does not provide decisive information and routine follow-up of EEG is not recommended.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.14 no.2
• /
• pp.183-193
• /
• 2001

Background: Ramsay Hunt syndrome is a disease that cause faical palsy, ear pain, ear vesicle, tinnitus, hardness of hearing by geniculate ganglion herpes. Ramsay Hunt syndrome could be taken two sides view of herpes zoster and facial palsy. In traditional oriental medicine Ramsay Hunt syndrome could be diagnosed as heat and dryness syndromes. Object: These studies are clinical observations about two Ramsay Hunt syndrome patient cases that is recovered under the treatment by herbal-acupuncture therapy and moxibustion. Methods: For treatment in acute state, acupuncture therapy was used and in convalescent stage, herbal acupuncture therapy and moxibustion therapy were used. For diagnosis system, House-Brackmann system, Yanagihara's system used as diagnosis scales. Result&Conclusion: The results as follows. 1. Generally, to treat Ramsay Hunt syndrome, it is knwon that from invasion of virus to period of first effect a short term bring about good result, but in these two cases, though a long term. considerable effect was braught out. 2. In treating two cases, herbal acupuncture therapys what are called CF, JSD were used. satisfactory results was produced.

• The Plant Pathology Journal
• /
• v.36 no.3
• /
• pp.204-217
• /
• 2020

In nature, plants are always under the threat of pests and diseases. Pathogenic bacteria are one of the major pathogen types to cause diseases in diverse plants, resulting in negative effects on plant growth and crop yield. Chemical bactericides and antibiotics have been used as major approaches for controlling bacterial plant diseases in the field or greenhouse. However, the appearance of resistant bacteria to common antibiotics and bactericides as well as their potential negative effects on environment and human health demands bacteriologists to develop alternative control agents. Bacteriophages, the viruses that can infect and kill only target bacteria very specifically, have been demonstrated as potential agents, which may have no negative effects on environment and human health. Many bacteriophages have been isolated against diverse plant-pathogenic bacteria, and many studies have shown to efficiently manage the disease development in both controlled and open conditions such as greenhouse and field. Moreover, the specificity of bacteriophages to certain bacterial species has been applied to develop detection tools for the diagnosis of plant-pathogenic bacteria. In this paper, we summarize the promising results from greenhouse or field experiments with bacteriophages to manage diseases caused by plant-pathogenic bacteria. In addition, we summarize the usage of bacteriophages for the specific detection of plant-pathogenic bacteria.

• Tribology and Lubricants
• /
• v.30 no.6
• /
• pp.356-363
• /
• 2014

Marine diesel engines operate in environments in which damage easily occurs from corrosion. Recently, damage to cylinder liners has increased from corrosion wear caused by increased engine power. This damage can cause serious problems in the economy. Thus, many researchers have treated and studied damaged cylinder liners. However, a method is necessary for real-time monitoring of damage to cylinder liners during operation of the engine, before serious damage can occur. This study carries out reciprocating friction and wear tests on a cast iron specimen under various corrosion atmospheres and verifies the variations of friction coefficient and friction surface. Additionally, the friction coefficient and friction status are predicted by using a neural network that learns the vibration and frequency spectrum data from an acceleration sensor. According to our conclusions, amplitude is distributed highly at high frequencies, and values of standard deviation and kurtosis are high when damage to the friction surface is serious. The accuracy rate of the friction coefficient predicted by the neural network is over 80% of the real measured value without NaCl, and application of the neural network is very effective for diagnosing the friction condition and damage to the cylinder liner.

• Journal of Korean Neurosurgical Society
• /
• v.29 no.3
• /
• pp.411-419
• /
• 2000

Hematomyelia is an extremely rare condition that cause severe neurological symptoms. We reported 4 cases of spontaneous hematomyelia, two cases of cavernous angioma and two cases of hematoma. In all patients, the clinical course was progressive ; motor and sensory abnormalities below the lesion and voiding difficulties were the common presenting symptom complex. The preoperative diagnosis was made by magnetic resonance imaging and the all patients underwent surgical exploration. Complete removal of hematoma was done in 3 patients and complete evacuation after aspiration of hematoma were performed in one patients. Neurological function did not worsen postoperatively in any patients. The early diagnosis with magnetic resonance imaging and immediate surgical treatment of the hematoma and the associated vascular malformation are considered to be the best way to halt the progression of the disease.

• Journal of Yeungnam Medical Science
• /
• v.12 no.1
• /
• pp.141-148
• /
• 1995

The Magnetic resonance imaging has been used widely to evaluate the disk position without any interruption of the TMJ structures, and the dynamic MRI presenting computed serial imaging or the video-recorded simulation images is thought to be very effective to evaluate the disk position under function. This is to study the correlation between the clinical diagnosis and the findings of dynamic MRI for diagnosis of internal derangement of the 7 patients were examined clinically, and the movement of TMJ meniscus was reviewed in the dynamic MRI. MRI was very reliable to diagnose the amount of anterior displacement of articular disc, the structural abnormality of temporomandibular joint, the cause of functional limitation, and to differentiate the muscle related pain & dysfunction.

• Korean Journal of Head & Neck Oncology
• /
• v.35 no.1
• /
• pp.25-27
• /
• 2019

Lipoblastoma is a rare benign tumor with 80-90% occurring in children less than 3 years of age and 40% occurring in children less than 1 year of age. The most common site of incidence is limb, and then trunk. Neck is the rare site of incidence. The main symptom that the patient complains about is a rapidly growing neck mass without pain. When the size of mass increases, it can cause dyspnea, Horner's syndrome. Lipoblastoma is usually diagnosed as a lipoma in the fine needle aspiration. Since it is not differentiated from lipoma, liposarcoma, and hibernating adenoma in CT and MRI, the definitive diagnosis is histologic diagnosis through surgical resection. The treatment is complete surgical resection. And recurrence rate is 9-25% due to incomplete resection. Authors report this case with a review of literatures since we experienced a case of lipoblastoma diagnosed histopathologically after surgical treatment of neck mass.