• Title/Summary/Keyword: Catching-up

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Early Biologic Treatment in Pediatric Crohn's Disease: Catching the Therapeutic Window of Opportunity in Early Disease by Treat-to-Target

  • Kang, Ben;Choe, Yon Ho
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.21 no.1
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    • pp.1-11
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    • 2018
  • The emergence of mucosal healing as a treatment goal that could modify the natural course of Crohn's disease and the accumulating evidence showing that biologics are most effective in achieving mucosal healing, along with the success of early treatment regimens for rheumatoid arthritis, have led to the identification of early Crohn's disease and development of the concept of catching the therapeutic window during the early disease course. Thus, an increasing number of pediatric gastroenterologists are adopting an early biologic treatment strategy with or without an immunomodulator. Although early biologic treatment is effective, cost and overtreatment are issues that limit its early use. Currently, there are insufficient data on who will benefit most from early biologics, as well as on who will not need early or even any biologics. For now, top-down biologics should be considered for patients with currently known high-risk factors of poor outcomes. For other patients, close, objective monitoring and accelerating the step-up process by means of a treat-to-target approach seems the best way to catch the therapeutic window in early pediatric Crohn's disease. The individual benefits of immunomodulator addition during early biologic treatment should be weighed against its risks and decision on early combination treatment should be made after comprehensive discussion with each patient and guardian.

The technological innovation patterns of component suppliers in the post catching-up period : The case study of component suppliers in mobile phone industry (탈(脫) 추격체제에서 부품업체의 기술혁신활동: 휴대전화 부품업체 사례연구)

  • Song, Wi-Chin;Hwang, Hye-Ran
    • Journal of Korea Technology Innovation Society
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    • v.9 no.3
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    • pp.435-450
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    • 2006
  • As technological capabilities have enhanced, the patterns of innovation activities of latecomer firms changed to post catch-up mode. The purpose of this research is to provide conceptual frameworks for post catch-up mode of innovation activities, based on the case study on Korean mobile phone industry. It presents the possibilities of architectural innovation of latecomer firms, which is stimulated by the co-operative innovation activities between component suppliers and users from the initial stage of final product development.

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Fiscal Policy and Redistribution in a Small Open Economy with Aging Population

  • Jung, Yongseung
    • East Asian Economic Review
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    • v.25 no.4
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    • pp.361-401
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    • 2021
  • This paper sets up a two agent small open economy with monopolistically competitive firms and catching up with the Joneses to investigate the labor and capital Laffer curve, taking into account aging population along the line of Auray et al. (2016), Galí and Monacelli (2005), and Trabandt and Uhlig (2011). The paper finds that the higher the market power of firms is, the larger the consumption inequality between asset holders and non-asset holders is in the economy with aging population. It also finds that there is room for government to increase the tax revenue by raising tax rates under the economy with higher markup, as households will work more hours to compensate for their loss of labor income to tax hikes. The expected maximum tax revenue is likely to shrink with progressive taxations, since non-asset holders with additional dividend income work less and consume more. The paper finds that the fiscal multiplier decreases with the degree of progressive redistribution.

Consumption Capital, Cultural Capital and Technology Catch-up in Cultural Industries: An Economic Model of Catch up in Cultural Industries (소비자본, 문화자본과 문화산업 기술추격: 문화산업 기술추격의 경제이론)

  • Ok, Sung-Soo
    • Journal of Technology Innovation
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    • v.17 no.1
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    • pp.205-221
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    • 2009
  • Since second half of 1990s, Korean "Han-Ryu" focuses international attention, which means Korean cultural industries increase their exports. However, traditional theories of international trade in cultural industries could not explain this phenomenon of increasing cultural goods from developing countries. Using the fact that Becker(1996)'s 'consumption capital' can increase productivity in cultural industries as well as contribute to form 'taste' for new cultural goods. This study suggests the proper conditions for catching-up of developing countries in cultural industries through comparative statistics.

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Speed of Catch-up and Digital Divide: A Study of Three Information Communication Technologies for 44 African Countries.

  • Shamba, Kudzai;Jeon, Seong-Min;Jang, Yu-Sang
    • 한국벤처창업학회:학술대회논문집
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    • 2018.11a
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    • pp.277-281
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    • 2018
  • Information system has been at center of economic development in several developed countries, and as Africa envision to improve its global economic competitiveness it is important to assess penetration rate the digital divide and catch-up effect over the years. This paper examined whether there exists digital divide and if so, is it narrowing over time and whether the ICT is converging with time in the African countries. Three technologies namely mobile-cellular, internet and fixed broadband were used to measure the digital divide and the catch-up effect. Gamma and sigma convergence methodology together with averaged penetration ratios were used to assess the cross-country performance of each technology. This study confirms both the narrowing of digital divide and convergence of ICT in all three technologies for both total group and subgroups. The digital gap was narrowing over time and the low-income countries were catching up faster to the middle-income countries in all three technologies. However, there are marked differences exhibited in the speed of narrowing digital divide and the speed of convergence between the total groups and the subgroups of countries. Some policy implications were discussed in the conclusion and they can be utilized in designing developmental ICT policies in each technology case for individual countries.

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Who demands the Survey of Industry Demand?: Paradox of Demand-Based Engineering Education Under Catch-up Paradigm (누가 '산업체 수요 조사'를 수요하는가? : 추격형 수요기반 공학교육의 역설)

  • Han, Kyong-hee
    • Journal of Engineering Education Research
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    • v.19 no.4
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    • pp.72-82
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    • 2016
  • In Korea, engineering education based on industry demand is highly emphasized; the survey of industry demand or company satisfaction is frequently conducted. Although engineering schools have often attempted and implemented the reform of engineering education, it was found that company satisfaction with college education was always low. In this context, this study aimed to find the cause of the low satisfaction. To this end, the social background for the active survey of industry demand and company satisfaction, and its progress were investigated. The findings of this study showed that the survey of industry demand in Korea has limitations in improving the quality of college education or developing its future demand, contrary to its intention. This industry demand based approach has its historical and social root in the Korea-specific model of the catching-up style industry development and technology innovation. Therefore, it is difficult to establish appropriate academy-industry relations and discover future vision based on this model. This study presents a new way to understand and develop the future-oriented industrial and social demand, not just arguing for the uselessness of the survey of industry demand in engineering education.

Improvement of Sea Eel Pots (붕장어 통발의 개량)

  • KO Kwan-SoH;KWON Byeong-Guk
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.20 no.2
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    • pp.95-105
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    • 1987
  • Traditional sea Eel pots can be divided into two groups such as bamboo and plastic pots, however they are nearly same in a shape with one entrance and fishing efficiency, except their materials. Very few yet have been studied on their catching methods or catching mechanisms at the view point of behavior. Accordingly, we have designed tubular pots in order to fill up faults of traditional fishing gear construction and behaviors of sea eel. The suitable tubular pots was decided by comparative experiments in the water tank and the fishing efficiency was compared through the field experiments. The results obtained are as follows : 1. The differences between traditional plastic pots and improved tubular pots are firstly two entrances in both ends of tube without holes, secondly flapper nets are fixed at the end of each cone, and thirdly a bait bag is fixed at the center of pot. 2. The standard size of the suitable tubular pot is: $$Tube\;:\;\phi\;12\~13{\times}L80\;cm$$, $$Cone\;:\;Inside\;ring\;\phi6{\times}D5\;cm$$, Flapper : L10 cm. 3. The fishing efficiency of tubular rots is 2.3 times better than that of plastic pots.

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An International Comparison of Technological Systems : The Case of CNC Machine Tools in Korea, Sweden, and U.S.A.

  • Sung, Tae-Kyung;Carlsson, Bo
    • Journal of Technology Innovation
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    • v.12 no.2
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    • pp.21-46
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    • 2004
  • Focusing on a product, this paper reconstructs the concept of technological systems first introduced by Carlsson and Stankiewicz (1991). Based on the model and our earlier works, we compare the salient features of technological systems for computer numerically controlled (CNC) machine tools in Korea, Sweden, and the United States.. We also try to measure the performance of the systems in an international comparison. Major findings are as follows: (1) The length of 'learning period' for local (national) technological system is substantial, even though it is a catching-up case. (2) The key success factor of the technological system appears to be the connectivity among various actors or infrastructures, rather than just the existence or formation of those. (3) In three countries' experience, the government played an important role in the formation of each own technological system. (4) The performance of Korea's technological system for CNC machine tools during the past two decades(1981-97) seems to be better than that of Sweden and the U.S. Lastly, many policy implication are presented.

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Developing the Impact Testing Module with LabVIEW (랩뷰를 이용한 FFT 분석기의 충격시험모듈 개발)

  • Choi, Ki-Soo;Jeon, Soo-Hong;Jeong, Weui-Bong
    • Proceedings of the KSME Conference
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    • 2007.05a
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    • pp.885-890
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    • 2007
  • Fast Fourier Transformation(FFT) is one of the most useful way to analyze response signal for the purpose of grasping the dynamic characteristics of system. Vibration test using impact hammer is typical and simple experimental method widely used for catching hold of dynamic peculiar characters and modal behaviors of system. In this thesis, impact testing module for NI-PXI equipment is developed. The analyzing and visualizing module are developed with LabVIEW tool. A user can see quickly and easily modal shape of system after analyzing acquired data. This developed module will be expected to build up more convenient and serviceable measurement system.

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What lessons can China learn from the Japanese prolonged financial slump?

  • Suzuki, Yasushi;Sohrab Uddin, S.M.
    • Journal of Contemporary Eastern Asia
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    • v.10 no.1
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    • pp.55-71
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    • 2011
  • China has been experiencing high economic growth along with massive change in its industrial structure. How will the industrial structure change affect the Chinese economy? Similar changes were observed by Japan, when the Japanese banking system fell into a structural failure in terms of the inability to respond to the paradigm shift from "catching up" to "frontier economy." This paper is undertaken to highlight the lessons that China can learn from Japan's prolonged financial slump. We point out that big cities in China have already shifted to frontier economy and major provinces are on the same trend. We argue that in spite of economic reform reshaping the Chinese banking system, the financing pattern of state owned commercial banks (SOCB) is not in line with the industrial change. The Chinese banking system should be overhauled or transformed to respond to the increasing uncertainty along with the paradigm shift. Otherwise, China may fall into the same dilemma that Japan had faced in its industrial structure change.