• Journal of Ginseng Research
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• 제44권1호
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• pp.1-7
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• 2020

The sense of vision is the primary means by which we gather information from our surroundings, and vision loss, therefore, severely compromises the life of the affected individuals, their families, and society. Loss of vision becomes more frequent with age, and diabetic retinopathy, age-related macular degeneration, cataracts, and glaucoma are the major causes of vision impairment. To find active pharmacological compounds that might prevent or ameliorate the vision-threatening eye diseases, numerous studies have been performed, and some botanical compounds, including those extracted from ginseng, have been shown to possess beneficial effects in the treatment or prevention of common ocular diseases. In this review, we summarize the recent reports investigating the therapeutic effects of ginseng and ginsenosides on diverse ocular diseases and discuss their therapeutic potential.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2008년도 춘계학술발표회
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• pp.63-64
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• 2008

• 대한족부족관절학회지
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• 제17권4호
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• pp.321-324
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• 2013

Xanthoma is a relatively rare soft tissue lesion on the Achilles tendon and is usually associated with hyperlipidemia (lipid metabolism abnormality), mental retardation, cataract and atherosclerotic disease. We report on a case of normolipidemic bilateral Achilles tendon xanthoma without any notable cause. We herein describe the case where we achieved a satisfactory result by subtotal resection.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1998년도 제50차 추계 학술대회 연제집
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• pp.74-75
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• 1998

• Archives of Pharmacal Research
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• 제29권7호
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• pp.577-581
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• 2006

Oxidative mechanisms are thought to have a major role in cataract formation and diabetic complications. Antioxidant enzymes play an essential role in the antioxidant system of the cells that work to maintain low steady-state concentrations of the reactive oxygen species. When HLE-B3 cells, a human lens cell line were exposed to 50-100 mM glucose for 3 days, decrease of viability, inactivation of antioxidant enzymes, and modulation of cellular redox status were observed. Significant increase of cellular oxidative damage reflected by lipid peroxidation and DNA damage were also found. The glycation-mediated inactivation of antioxidant enzymes may result in the perturbation of cellular antioxidant defense mechanisms and subsequently lead to a pro-oxidant condition and may contribute to various pathologies associated with the long term complications of diabetes.

• 한국임상수의학회지
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• 제37권6호
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• pp.345-349
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• 2020

An 8-month-old female rabbit was presented with a white intraocular mass in the right eye. Slit-lamp biomicroscopy showed a white mass behind the iris, accompanied by rubeosis iridis and aqueous flare. Ocular B-scan ultrasonography revealed hyperechoic material within the anterior chamber connected with cataractous lens in the right eye. Signs deteriorated despite treatment, and enucleation was performed. Histopathologically, phacoclastic endophthalmitis due to Encephalitozoon cuniculi infection was confirmed. This was the first report of a client-owned rabbit affected with E. cuniculi-associated phacoclastic uveitis. Serological detection of anti-E. cuniculi antibodies should be considered to prevent potential zoonotic risk.

• 대한유전성대사질환학회지
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• 제22권2호
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• pp.37-45
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• 2022

Inherited metabolic disorders (IMD) are a large group of rare disorders affecting normal biochemical pathways. The ophthalmic involvement can be very varied affecting any part of the eye, including abnormalities of cornea, lens dislocation and cataracts, retina and the optic nerve, and extraocular muscles. Eye disorders can be initial symptoms of some IMD and can be clue for diagnosis of IMD. However, eye disorders can evolve later in the natural history of an already diagnosed metabolic disorder. Awareness of IMDs is important to facilitate early diagnosis and in some cases instigate early treatment if a patient presents with eye involvement suggestive of a metabolic disorder. Ophthalmological interventions are also an important component of the multisystem holistic approach to treating patients with metabolic disorders.

• 분석과학
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• 제7권1호
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• pp.53-64
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• 1994

아미노산의 광학 이성질체를 분리하는 방법을 확립하고 식품이나 생체에 있는 광학이성질체를 분리 정량하여 영양학이나 생화학적 관계를 연구한다. 필수아미노산 20종을 포함하여 총 38종의 d, l-from 아미노산을 검색 대상으로 삼았다. 단백질은 한국산 콩, 된장, 고추장, 간장, 분유 및 환자의 백내장을 시료로 하여 산 가수분해 후 esterification과 acylation으로 TFA-IPA 유도체를 만들어 chirasil val GLC column을 사용하여 분리하였다. 이성질화가 일어나는 아미노산은 alanine, aspartic acid, glutamic acid, phenyl alanine으로 식물성 시료인 된장에서는 d-alanine이 검출되었으나 동물성 시료인 백내장과 분유에서는 검출되지 않았다. 연령추정 등 생리적으로 이용이 가장 적적한 것은 분리능과 함량을 비교했을 때 aspartic acid였다. d-from 아미노산의 분율은 가정용 된장이 3~6, 시판용 된장이 약 3%, 간장이 2~4%, 콩이 약 1%, 백내장 시료에서 1~2%, 분유에서 1.0~1.5%로 검출되었으며, 숙성 발효시 광학이성질체의 변환이 현저함을 알 수 있다.

• Journal of Trauma and Injury
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• 제24권2호
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• pp.61-67
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• 2011

Purpose: Lawn trimmers are widely used to cut the weeds around graves in South Korea, but they can cause ocular injury. We investigate at the emergency room the incidence and the clinical features of ocular trauma induced by lawn trimmers. Methods:The authors analyzed 106 patients who visited Konyang University Hospital's emergency room from March 1, 2007, to October 31, 2011, because of ocular trauma caused by a lawn trimmer. Patients were sorted into two groups, severe ocular injury and mild ocular injury. Results: Over a 5-year period, 106 patients with ocular trauma caused by a lawn trimmer underwent clinical study. Most of the patient (103 patients) were males, and the average age of the patients was $51.75{\pm}11.66$ years. The incidence of ocular trauma peaked in the sixth decade of life. Most injuries occurred between July and September. Severe ocular injury developed in 46.2% of all patients. As age increased, so did the severity of the ocular injury. The impacting object was a small stone in 43.4% of all patients. Nobody wore protective gear. The most common diagnosis were corneal abrasion, followed by intraocular foreign body, corneal laceration, and sclera laceration. Fifty-four patients were followed up, and thirty-six patients of them had severe injury. The most common complication was a traumatic cataract. Conclusion: Ocular trauma induced by a lawn trimmer is more severe than general ocular trauma. We suggest that everyone using a lawn trimmer should wear protective gear and follow safety guidelines.

• 한국안광학회지
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• 제19권3호
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• pp.403-406
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• 2014

목적: 울산지역의 안질환 발생환자에 있어서 연령별에 따른 특정질환을 알아보고자 하였다. 방법: 울산지역의 안과병원을 내원한 환자 300명을 대상으로 환자의 성별, 초진당시 연령, 과거력, 진단명 등을 기준으로 분석하였다. 결과: 10대의 경우에는 각막염이 가장 많은 비중을 차지하였고, 20대는 건조증과 각막염, 30대는 콩다래끼와 결막염, 40~50대의 경우에는 결막염, 60대의 경우에는 결막염과 백내장이 많은 비중을 차지하는 것으로 나타났다. 결론: 주요 안질환 원인으로는 10~20대는 콘택트렌즈의 부적절한 착용과 스마트폰과 컴퓨터 매체 등의 장기간 사용, 30~50대는 알러지성 결막염이나 화학물질 등으로 인한 반응 등 여러 가지 요인으로 분석되는데 특히, 공업지역의 특성상 타지역 보다 결막염의 발생빈도가 더 높게 나타났으며, 50대 중반부터 60대 이상은 일종의 노화현상이 원인인 것으로 분석되어진다. 따라서, 본 연구결과는 울산지역에서 발생될 수 있는 안질환 예방을 위한 기초 자료로 활용될 수 있을 것으로 여겨진다.