• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.4
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• pp.423-429
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• 2009

This study was conducted to investigate the effects of pine (Pinus densiflora) needle extracts on hepatic antioxidative system in rats fed high-cholesterol diet. Eight-week old Sprague Dawley rats were divided into four groups; normal diet group (CON), 0.5% cholesterol diet group (0.5% CHOL), 0.5% cholesterol diet and pine needle extracts prepared by using hot water group (HOT water), and 0.5% cholesterol diet and pine needle extracts prepared by using sub-supercritical $CO_2$ group (Sub-supercritical). The serum ALP, AST, and ALT activities were increased by 0.5% cholesterol diet supplementation, but treatment with pine needle extracts showed decrease compared with 0.5% CHOL group. The SOD activity in liver at 0.5% cholesterol diet group was more decreased than control group while Sub-supercritical group had significantly higher SOD activity than 0.5% CHOL group. Moreover, groups with pine needle extracts supplementation had higher level of GPx in liver than 0.5% cholesterol diet group. These results suggest that pine needle extracts increased antioxidative activities.

• Journal of the Korean Institute of Landscape Architecture
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• v.36 no.5
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• pp.64-72
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• 2008

The purpose of this study is to compare a habitat suitability grid unit included within a radius of 100m and $1km^2,\;2km^2,\;4km^2$ watershed units in order to predict suitable habitats for Chungcheong province's endangered leopard species(Prionailurus bengalensis). Other developed countries have carried out habitat assessment and established management policies for species conservation using such methods as HEP(Habitat Evaluation Procedures), HSI(Habitat Suitability Index) and GAP(Gap Analysis Program), etc. In accordance with these studies, many evaluation methods for habitat conservation have been proposed in Korea, but these studies are lacking in consideration of analytic units and general application of analysis results. This study predicted leopard habitat using a logistic regression analysis according to analytic units by data from 56 location and 8 sources of environmental data, including elevation, slope, forest area, land cover, roads, water, broadleaf trees, and human habitation. Moreover, the habitat suitability assessment unit was confirmed by a model comparison process encompassing model explanation. verification, and application on a regional scale. Results showed that assessment methods that took into consideration areas in and around the location points were beneficial in predicting habitat and that the assessment unit was appropriate for a 30m grid unit including areas within a radius of 100m and a $1km^2$ watershed unit in Chungcheong Province. This study suggests a method for regional habitat conservation to complement existing conservation area selection methods, and the results are expected to be used in conservation area selection and ecosystem management policies for endangered species.

• Proceedings of the KAIS Fall Conference
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• 2000.10a
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• pp.30-33
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• 2000

최근 국내에서도 관 동맥 질환 환자의 수가 급증하고 있으며, 관 동맥 질환의 치료 방법인 관 동맥 성형 술은 관 동맥 stent의 도입에 의하여 보편화되어 국내에서 년간 5000개 이상의 stent가 시술되고 있다. 그러나 stent는 고가(1,200천원/개)로 전량 수입에 의존하고 있으며, 시술 후 사망까지 이를 수 있는 혈전에 의한 급성 페쇠와 재 협착이 문제점이다. 이를 위한 한가지 방법이 생체 적합성이 뛰어난 복합 stent의 개발인데 SiC나 Carbon을 coating한 stent는 시술 후 혈전 형성을 억제하는 것으로 알려져 있다. 특히 가장 순수한 Pyrolytic carbon은 hemocompatibility가 탁월하고 기밀 성이기 때문에 본 연구에서 그의 CVB-Kinetics를 연구코저 하는 것이다. methane으로부터 pyrolytic carbon의 CVD는 온도에 따라서 다양한 구조를 가지며 따라서 그의 mechanism도 다양하다는 것은 잘 알려져 있다. 더구나 광간(균질)반응과 표면(불균질)반응의 정량적 관계에 따라서도 다르다는 것도 확인되었다. 그러나 stainless steel 316L로 만든 stent는 12 - 15 %의 Ni과 2%의 Mo을 함유해서 금속성을 잃지 않는 저온(600℃)에서도 pyrolytic carbon의 속매적 CVD가 가능함을 그리고 SiC의 코팅에 적합한 buffer layer 역할을 함을 확인하였다. 그리하여 본 연구는 반응기 설계에 필요한 저온 촉매적 pyrolytic carbon의 CVD-kinetics의 연구결로 그의 mechanism과 함께 rate law 식을 유도, 확인하였으며 600℃, 90kPa에서 P/sub ch4//P/sub H2/=5:1과 체류시간 1.8 sec가 최적임을 발견하였다. 이때 석출속도 11.2 g-mol/g-cat.h 혹은 두께속도로 73 nm/sec를 나타내었다.메타놀-물 (1 : 1) 유출액에서 $(0.80\;{\mu}g)$ 검출되었다. 하면 morey eel내장에서 얻은 독물질도 DEAE-셀루로즈에서 ST-1 과 ST-2로 나누어지며, 이 ST-1의 TLC, HPLC 및 알루미나 컬럼상의 거동이 파랑비늘돔에서 얻은 ST-1의 그것과 같으므로 scaritoxin으로 보고한 ST-1은 ciguatoxin의 형태인 less polar cigutoxin (LPCTX) 으로 생각된다.에서 각각 대조구의 57, 413 및 315% 증진되었다. 거품의 열안정성은 15분 whipping시, pH 4.0(대조구, 30.2%) 및 5.0(대조구, 23.7%)에서 각각 $0{\sim}38.0$ 및 $0{\sim}57.0%$이었고 pH 7.0(대조구, 39.6%) 및 8.0(대조구, 43.6%)에서 각각 $0{\sim}59.4$ 및 $36.6{\sim}58.4%$이었으며 sodium alginate 첨가시가 가장 양호하였다. 전체적으로 보아 거품안정성이 높은 것은 열안정성도 높은 경향이며, 표면장력이 낮으면 거품형성능이 높아지고, 비점도가 높으면 거품안정성 및 열안정성이 높아지는 경향이 있었다.protocol.eractions between application agents that are developed using different languages. Dynamic agent invocation is accomplished by Java Native Interface(JNI) that links two heterogeneous methods, and by KQML language interface that facilitates the communications between heterogeneous agents. This scheme of dyna

• The Korean Journal of Physiology and Pharmacology
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• v.5 no.1
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• pp.55-63
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• 2001

In macrophages, lipopolysaccharide (LPS) alone or in combination with $interferon-{\gamma}\;(IFN-{\gamma})$ has been shown to release a nitric oxide (NO) through the increase of the transcription of the inducible nitric oxide synthase (iNOS) gene. To investigate the exact intracellular signaling pathway of the regulation of iNOS gene transcription by LPS plus $IFN-{\gamma},$ the effects of protein tyrosine kinase (PTK) inhibitor and protein kinase C (PKC) inhibitors on NO production, iNOS mRNA expression, nuclear $factor-_{\kappa}B\;(NF-_{\kappa}B)$ binding activity and the promoter activity of iNOS gene containing two $NF-_{\kappa}B$ sites have been examined in a mouse macrophage RAW 264.7 cells. LPS or $IFN-{\gamma}$ stimulated NO production, and their effect was enhanced synergistically by mixture of LPS and $IFN-{\gamma}.$ The PTK inhibitor such as tyrphostin reduced LPS plus $IFN-{\gamma}-induced$ NO production, iNOS mRNA expression and $NF-_{\kappa}B$ binding activity. In contrast, PKC inhibitors such as H-7, Ro-318220 and staurosporine did not show any effect on them. In addition, transfection of RAW 264.7 cells with iNOS promoter linked to a CAT reporter gene revealed that tyrphostin inhibited the iNOS promoter activity through the $NF-_{\kappa}B$ binding site, whereas PKC inhibitors did not. Taken together, these suggest that PTK, but not PKC pathway, is involved in the regulation of the iNOS gene transcription through the $NF-_{\kappa}B$ sites of iNOS promoter in RAW 264.7 macrophages by LPS plus $IFN-{\gamma}$.

• Restorative Dentistry and Endodontics
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• v.20 no.2
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• pp.508-526
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• 1995

This experiment was performed to study mechanisms of desensitization by chemical desensitizing agents in hypersensitive dentin and compare effects of these agents by measuring the activity of intradental nerves and observing their occluding aspects on dentinal tubules with SEM over time after application of chemical desensitizing agents to the exposed dentinal surfaces. Canines of adult cats weighing 2-3 kg were cross-sectioned at 1.5 mm from incisal apex, and the smear layer of the exposed dentinal susface was removed by 32 % $H_3PO_4$ for 15 sec. Chemical desensitizing agents such as 10% $SrCl_2$, 5% $KNO_3$ and 30% $K_2C_2O_4$, were applied to the exposed dentin surfaces for 2 minutes. Intradental nerve activity was measured immediately after application of the agents, at 15 minutes and at 30 minutes by stimulating with 4M NaCl. To compare occluding ability of desensitizing agents on dentinal tubules in vivo and in vitro, the structures of the exposed dentinal surfaces of nonvital and vital teeth were morphologically observed by SEM. The results obtained were as follows : 1. Intradental nerve activity was decreased immediately after the application of 10 % $SrCl_2$, 5% $KNO_3$ and 30% $K_2C_2O_4$. (p<0.01), among which 30% $K_2C_2O_4$. showed the highest desensitizing effect(p<0.01). 2. The immediately decreased intradental nerve activity after application of 10 % $SrCl_2$ and 5% $KNO_3$ was increased over time. 10% $SrCl_2$ and 5% $KNO_3$ showed no desensitizing effect respectively at 30 minutes and at 15 minutes after application. 3. The immediately decreased intradental nerve activity after application of 30 % $K_2C_2O_4$ was persistently continued during the period of observation (p<0.01). 4. Precipitates of $SrCl_2$ and $KNO_3$ were not noted on the exposed dentinal surfaces and within dentinal tubules by SEM examination. On the other hand, 30 % $K_2C_2O_4$ produced precipitates on the exposed dentinal surfaces and openings of dentinal tubules without any formed preciptates within dentinal tubules. 5. Ten percent $SrCl_2$, 5 % $KNO_3$ and 30 % $K_2C_2O_4$ showed no differences in their occluding aspects on dentinal tubules either in vivo or in vitro studies and either immediately following application or at 30 minutes. These results suggest that the desensitizing effect of $SrCl_2$ and $KNO_3$ is resulted from their reducing effect on the intradental nerve activity rather than from their precipitates' occluding the dentinal tubules. However, desensitizing effect of 30 % $K_2C_2O_4$, is probably resulted from its precipitates' occluding the openings of the dentinal tubules as well as from it's reducing effect on the intradental nerve actibity.

• KIPS Transactions on Computer and Communication Systems
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• v.5 no.12
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• pp.463-470
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• 2016

With the growing demand for MAC-based system, the need for digital forensic techniques of these system has been increasing. In the digital forensic analysis process, sometimes analysts have recovered the deleted files when they prove the allegations if system user try to remove the evidence deliberately. Research and analysis that recover the deleted files from a file system constantly been made and HFS+ that is a file system of MAC-based system also has been researched. Carving techniques primarily has been used to recover the deleted file from HFS+ a file system because metadata of folder or file overwrite metadata of a deleted file when file is deleted from a file system on HFS+ characteristic. But if the file content is saved by separated state in a file system, Carving techniques also can't recover the whole or a part of the deleted file. In this paper we describe technique the deleted file recovery technique using HFS+ file system a journal. This technique that is suggested by existing research and analysis result is the technique that recover the deleted file by metadata that is maintained in a journal on HFS+ file system. but this technique excludes specific files and this problem needs to be reformed. In this paper we suggest algorithm that analysis a journal of HFS+ file system in detail. And we demonstrate that the deleted file cat be recovered from the extracted metadata by this algorithm without the excluded file.

• Resources Recycling
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• v.8 no.5
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• pp.34-43
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• 1999

An elecmc arc cracking reaclor is developed for the productiol~o f ieusuble fuel gas by the thennal destruction of waste oil. The churaclensucs of product gas and ~esiduesf rom arc crachng of wnste lubr~cat~nogil are sludird. Thc product gas is mainly coruposcd of hydrogen 135-4076), acetylene (13-4076), ethylene 13-476) and olher hgdrocnrbons. The contenr of carbon monomde, one or the main product in a conventional low-temperature Lhennal cracking umt, 1s very slnvll in lhis atc cracking expcnmcnt. Total calocctic wlue of product gas shows 11,000-13.000 kcizlkg, which is hiph cnough to use as a ~ L I I I Cga~ s . and the concentralions oC loxic gases arc well below the rcguliltury emission critena The GCIMS analysis of llquld-phase residues shows that the high rnalccular welgllt hydrocilrbons in the waste oil arc cracked into the low malecular weight hydrocarbons snd hydroem,. The dehydrogcnntion is found lo be Lhe main cracking rcacuon due lo the high temperalure ~ ~ ~ d ubcyc edle ctric arc. The average parucle size of soot as the solid-phase residue is 10 3 wm, and the conlents of cabon a ~ hdea vy metals are abovc 60% and under 0.01 ppm, respecttrely. Thc utllizvtion or sool, as industl-id1 rcsource seems lo he reasible aIter refimng.

• Journal of Veterinary Clinics
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• v.24 no.2
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• pp.104-108
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• 2007

The purpose of the study is to evaluate the clinical antagonistic effect of atipamezole(0.25 mg/kg, IM) in cats anesthetized with tiletamine-zolazepam ($Zoletil^{(R)}$, 10 mg/kg, IM) and medetomidine (0.05 mg/kg, IM). Twelve healthy 1 year old Korean mixed breed cats were used for this study. They were 4 males and 8 females. These cats were randomly assigned to two groups. One was control group ($Zoletil^{(R)}$ + medetomidine, ZM), and the other was treatment group ($Zoletil^{(R)}$ + medetomidine and antagonism by atipamezole, ZMA). All cats were examined 15 minutes before, 5, 25, 65 and 105 minutes after administration of tiletamine-zolazepam and medetomidine. Atipamezole was injected intramuscularly 20 minutes after ZM administation. Recovery time, heart rate, respiratory rate, total plasma protein and blood glucose were significantly different between ZM group and ZMA group (P<0.05). However, rectal temperature was not significantly different between ZM group and ZMA group. Two groups were able to induce sternal recumbency within 2 minutes and lateral recumbency within 4 minutes after the anesthetics injection. Mean sternal position time ($mean{\pm}SD$) was $174.0{\pm}44.6\;and\;116.2{\pm}27.3$ minutes, and mean standing position time was $210.8{\pm}45.6\;and\;154.2{\pm}21.1$ minutes in ZM and ZMA group, respectively. In these two groups, adverse effects during recovery time from anesthesia were not seen. As a result, the ZMA group had a faster recovery than the ZM group. Thus it was concluded that atipamezole could exert a useful reversal effect in cats anesthetized with medetomidine-tiletamine/zolazepam combination.

• Journal of Veterinary Clinics
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• v.31 no.6
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• pp.477-482
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• 2014

The aim of this study was to investigate and compare technique, surgical time, and complications of laparoscopic ovariectomy using $LigaSure^{TM}$ and bipolar vessel sealing system in cats. Laparoscopic ovariectomy was performed under general anesthesia on 10 healthy female cats admitted for elective ovariectomy. Surgery was performed through three midline portals. Each ovary was randomly-assigned to removal by use of either $LigaSure^{TM}$ or bipolar vessel sealing system. Duration of predetermined surgery intervals and complications were compared. Bipolar OVE ($2:16{\pm}1:14$ minutes) took significantly longer surgical time compared to the $LigaSure^{TM}$ OVE ($1:24{\pm}0:59$ minutes, P = 0.021). The ovarian pedicle fat and obesity did not influence surgery duration. Intraoperative hemorrhage occurred with bipolar OVE in three cats, but had no significant influence on surgical time. The results suggest that both $LigaSure^{TM}$ and bipolar devices appear to be effective, but $LigaSure^{TM}$ can be used as a stand-alone device that decreases surgical time and complication compared with bipolar vessel sealing system.

• Korean Journal of Medicinal Crop Science
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• v.26 no.4
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• pp.271-280
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• 2018

Background: Astragalus membranaceus is a well known oriental medicinal herb. The polysaccharides of the aboveground parts (AMA) and the radix (AMR) of A. membranaceus are the most important functional constituents. Methods and Results: The aim of this study was to determine the effects of AMA and AMR on the oxidative damage induced in the skeletal muscle of rats subjected to exhaustive exercise. Sprague-Dawley rats were randomly divided into exercise and non-exercise groups; in the groups receiving the test compounds, AMA and AMR were administered orally for 30 days. Skeletal muscle samples were collected from each rat after running to exhaustion on a treadmill to determine the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) and the concentation of malondialdehyde (MDA). The antioxidant enzyme activities of SOD and GSH-Px of skeletal muscle of AMA- and AMR-treated groups were significantly higher than those of the control and commercial sports drink (SPD)-treated groups in exhaustive exercise rats. In addition, MDA concentrations in the skeletal muscle of the AMA- and AMR-treated groups were significantly lower than those of the control and SPD-treated groups. In the present study, the effects of AMA and AMR on exercise endurance capacity were also evaluated in mice subjected to a swimming exercise test. AMA and AMR supplementation prolonged the swimming time of mice and enhanced exercise endurance capacity. AMA and AMR possess the ability to retard and lower the production of blood lactate, and prevent the decrease of serum blood glucose. Conclusions: These results showed that, AMR and AMA exerted beneficial effect in mice, increasing the activity of the antioxidant systems and inhibiting oxidative stress induced by exhaustive exercise. The compounds improved exercise performance and showed anti-fatigue effects against exhaustive exercise.