• Title/Summary/Keyword: Case-mix

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Effect of micro-silica on mechanical and durability properties of high volume fly ash recycled aggregate concretes (HVFA-RAC)

  • Shaikh, Faiz;Kerai, Sachin;Kerai, Shailesh
    • Advances in concrete construction
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    • v.3 no.4
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    • pp.317-331
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    • 2015
  • This paper presents the effect of different micro-silica (MS) contents of 5, 10 and 15 wt.% as partial replacement of cement on mechanical and durability properties of high volume fly ash - recycled aggregate concretes (HVFA-RAC) containing 50% class F fly ash (FA) and 35% recycled coarse aggregate (RCA) as partial replacement of cement and natural coarse aggregate (NCA), respectively. The measured mechanical and durability properties are compressive strength, indirect tensile strength, elastic modulus, drying shrinkage, water sorptivity and chloride permeability. The effects of different curing ages of 7, 28, 56 and 91 days on above properties are also considered in this study. The results show that the addition of MS up to 10% improved the early age (7 days) strength properties of HVFA-RAC, however, at later ages (e.g. 28-91 days) the above mechanical properties are improved for all MS contents. The 5% MS exhibited the best performance among all MS contents for all mechanical properties of HVFA-RAC. In the case of measured durability properties, mix results are obtained, where 10% and 5% MS exhibited the lowest sorptivity and drying shrinkage, respectively at all ages. However, in the case of chloride ion permeability a decreasing trend is observed with increase in MS contents and curing ages. Strong correlations of indirect tensile strength and modulus of elasticity with square root of compressive strength are also observed in HVFA-RAC. Nevertheless, it is established in this study that MS contributes to the sustainability of HVFA-RAC significantly by improving the mechanical and durability properties of concrete containing 50%less cement and 35% less natural coarse aggregates.

Studies on Antimutagenic and Lipotropic Action of Flavonoids of Buckwheats -Desmutagenic Activity of Buckwheat Leaf Extracts (메밀 Flavonoids의 항돌연변이원성 및 지질대사 조절기능에 관한 연구 -메밀 잎 에탄올 추출물의 항돌연변이원성 연구-)

  • 함승시;최근표;최용순;이상영
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.23 no.4
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    • pp.698-703
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    • 1994
  • In spore rec-assay using B. subtillus H17(rec) and M 45(rec) , the ethanol extract of buckwheat leaves showed antimutagenicity in condition of low concentrations, but its did comutagenicity in condition of high concentrations. In Ames test, the ethanol extract of buckwheat leaves reduced the mtabenicity of N-methyl-N' -nitro-N-nitrosoguaidine (MNNG), benzo (a) pyrene(B($\alpha$)P), 2-amino-fluorene(2AF), and 3-amino -1, 4-dime-thyl-5-H-pyrido(4, 3-b) indol(Trp-P-1) in Salmonella typhimurium TA98 and TA100. The ethanol extract was fractionated by hexane, ethylacetate, butanol and water. Among Them hexane fraction showed the highest inhibition rate on the mutagenicity of B($\alpha$)P, and so did chloroform fraction on the mutagenicity of MNNG in S. typhimurium Ta98 and TA100. To elucidate the antimutagenic mechanism of the ethanol extract, it was mixed and co-incubated with various metagens, S9 mix, and the bacteria with different experimental orders and different reaction times. The ethanol extract did not affect reversion rate of pre-mutated. S.typhimurium. However, when the ethanol extract was added to the mutagens before their interaction with S.typhimurium , it reduced the mutation rate to 152$\pm$12-273$\pm$18 colonies/plates in case of MNNG, and 135$\pm$13-195$\pm$10 colonies/ plates in case of B($\alpha$)P), showing strong desmutagenic activity.

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Physical and Mechanical Properties of Non-Cement Porous Concrete with Alkali-Activator Contents (알칼리활성화제 치환율에 따른 무시멘트 다공성 콘크리트의 물리·역학적 특성)

  • Kim, Dong-Hyun;Kim, Chun-Soo;Park, Chan Gi
    • Journal of The Korean Society of Agricultural Engineers
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    • v.55 no.2
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    • pp.59-64
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    • 2013
  • The present study is to evaluate physical and mechanical properties of porous concrete having non cement that mainly causes carbon emission. This study aims to explore eco-friendly concrete technology capable of reducing the amount of carbon emission due to the use of normal cement by substituting it with non cement porous concrete to which alkali-activator and blast-furnace slag powder are impregnated. As experimental variables, 5 %, 6 %, 7 %, 8 %, 9 % and 10 % of alkali-activator were substituted as binders and applied. Testing evaluated in this study were pH value, void ratio, compressive strength and residual compressive strength shown after being immersed in $H_2SO_4$ solution and $Na_2SO_4$ solution. The test results were compared with those tested with the use of porous concrete to which 400 $kg/m^3$ of unit cement amount was applied as binder. In consequence, it was concluded that; as for pH value, it was decreased than was the case in which cement was used, but increased with the more the use of alkali activator; as for void ratio and compressive strength, the mix proportion in which 9 % and 10 % of alkali activator were applied in terms of substitution ratio showed the result similar to the mixture in which 400 $kg/m^3$ of unit cement ratio was applied; and, as for residual compressive strength in the case of being immersed in $H_2SO_4$ solution and $Na_2SO_4$ solution, the compressive strength was increased, thus leading to improved chemical resistance.

A Study on the Characteristics of Design Utilizing a Visual Tactility -Focused on the Hair Design- (시각적 촉감을 활용한 디자인의 특성 연구 - 헤어 디자인을 중심으로 -)

  • Oh, Gang Su;Kim, Kyoungin
    • Journal of Fashion Business
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    • v.21 no.4
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    • pp.127-143
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    • 2017
  • In this study, we examine a variety of influences in the field of design and analysis about the value of visual tactile design. In hair design, through study on visual tactility, creative design inspiration in the field of hair design enables development of quality research. Research methods use Internet publications such as local and foreign data, analysis, and related research and book forms, such as network searches. library goes for consideration by a literature search. Contents of this study used review of the case and by visual tactility design, for this study, expressive characteristics by color, texture and form of hair design, from 2014-2017 trend shown in the last three years the expressions of visual tactility being used through the analysis of design by date of the case. Result of this study is, visual tactile design appearing in the areas of hair design, that are not of the rules that are active, abstract form, texture, described as a visual feel the promotion of effective, and light and high brightness is sweet tactile impression, high saturation was cold, dark color was hard and heavy, red system is warm and the blue system is cold sense. In general, design trend in hair for three years from 2014-2017, visual tactility in 2014 is a high saturation and unstructured also soft and bright colors. 2015 is on the overall shape, color, texture, hybrid design configuration is more. As of 2016, 2017 is curved and straight texture, appearance of the hybrid mix to maximize the visual tactility.

Evaluation of the MTHFR C677T Polymorphism as a Risk Factor for Colorectal Cancer in Asian Populations

  • Rai, Vandana
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.18
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    • pp.8093-8100
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    • 2016
  • Background: Genetic and environmental factors play important roles in pathogenesis of digestive tract cancers like those in the esophagus, stomach and colorectum. Folate deficiency and methylenetetrahydrofolate reductase (MTHFR) as an important enzyme of folate and methionine metabolism are considered crucial for DNA synthesis and methylation. MTHFR variants may cause genomic hypomethylation, which may lead to the development of cancer, and MTHFR gene polymorphisms (especially C677T and A1298C) are known to influence predispositions for cancer development. Several case control association studies of MTHFR C677T polymorphisms and colorectal cancer (CRC) have been reported in different populations with contrasting results, possibly reflecting inadequate statistical power. Aim: The present meta-analysis was conducted to investigate the association between the C677T polymorphism and the risk of colorectal cancer. Materials and Methods: A literature search of the PubMed, Google Scholar, Springer link and Elsevier databases was carried out for potential relevant articles. Pooled odds ratio (OR) with corresponding 95 % confidence interval (95 % CI) was calculated to assess the association of MTHFR C677T with the susceptibility to CRC. Cochran's Q statistic and the inconsistency index (I2) were used to check study heterogeneity. Egger's test and funnel plots were applied to assess publication bias. All statistical analyses were conducted by with MetaAnalyst and MIX version 1.7. Results: Thirty four case-control studies involving a total of 9,143 cases and 11,357 controls were retrieved according to the inclusion criteria. Overall, no significant association was found between the MTHFR C677T polymorphism and colorectal cancer in Asian populations (for T vs. C: OR=1.03; 95% CI= 0.92-1.5; p= 0.64; for TT vs CC: OR=0.88; 95%CI= 0.74-1.04; p= 0.04; for CT vs. CC: OR = 1.02; 95%CI= 0.93-1.12; p=0.59; for TT+ CT vs. CC: OR=1.07; 95%CI= 0.94-1.22; p=0.87). Conclusions: Evidence from the current meta-analysis indicated that the C677T polymorphism is not associated with CRC risk in Asian populations. Further investigations are needed to offer better insight into any role of this polymorphism in colorectal carcinogenesis.

Guided Bone Regeneration using Fibrin Glue in Dehiscence or Fenestration Defects Occurred by Maxillary Anterior Implants: Case Report (상악 전치부 임플란트 식립에 의한 열개 및 천공형 골결손 발생 시 조직 접착제를 이용한 골유도 재생술: 증례보고)

  • Chee, Young-Deok;Seon, Hwa-Gyeong
    • Journal of Dental Rehabilitation and Applied Science
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    • v.28 no.3
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    • pp.277-290
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    • 2012
  • Dental implants are universal restorative method on edentulous site in oral cavity and generally recognized by patients as well as clinicians. Rapid bone resorption of labial portion of maxillary anterior area is performed due to dental trauma, chronic periodontitis, and so on. Accordingly, Implants on maxillary anterior alveolar ridge with narrow labiopalatal width would lead to bony defects of dehiscence or fenestration. In this case, guided bone regeneration procedure is used to augment maxillary anterior alveolar ridge. It can have mechanical and biological advantages to mix tissue adhesive with bone graft materials in guided bone regeneration procedure. In these cases, when the dehiscence or fenestration defects was occurred by dental implants on maxillary anterior alveolar ridge with narrow labiopalatal width, guided bone regeneration procedures were performed with various combination of particle bone graft materials(allograft, xenograft, and alloplast) mixed with fibrin glue, excepting autogerous bone. We reported that all of 4 cases showed favorable alveolar ridge augmentations.

Flow and Combustion Characteristic in an Array of Multiple Pre-Mixed Methane/Air Flame Jets (메탄/공기 다중 제트 예혼합 화염에서의 유동과 연소특성)

  • Kim, Young-Su;Lee, Dae-Rae;Ha, Man-Yeong;Chang, Young-June;Jeon, Chung-Hwan;Cho, Seung-Wan;Kang, Kil-Young;Yu, Jae-Hyun
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.31 no.6 s.261
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    • pp.547-557
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    • 2007
  • This study was conducted to investigate the flow and combustion characteristic of the experimental burner which was manufactured for the reflection of the oven and broil burner features. As slot shape, spacing between slots, and slot arrangement of the exit area which emits the mixing gas are different in case of oven burners and broil turners, the purpose of this study is to know the affection of the flame interaction and combustion characteristic according to the change of shape factors such as slot shape, slot arrangement, and slot-to-slot spacing. With no relation of the slot shape, as the spacing between slots became narrow, the occurrence of a lift-flame was delayed. So the combustion was possible in the leaner region, but the appearance of yellow-tip became a little fast. Slit slot port had the broadest operating range among the other slot shapes. Specially, from the side of lift-flame, as the jet that spreads downstream in the longitudinal slot was nearly circular just a few slot lengths away from the orifice, slot-to-slot spacing of the Slit port was closer than the other ports. These results could be expected through the computer numerical method and had a good agreement. As the spacing between slots increased, in case of Slit and Mix port, NOx emission rate was constant or decreased, but the NOx emission of Hole port was increased. CO emission rate of Slit and Hole port was increased as the slot-to-slot spacing was broadened.

Evaluation of the Genotoxicity of Decursin and Decursinol Angelate Produced by Angelica gigas Nakai

  • Kim, Kang-Min;Kim, Tae-Ho;Park, Yun-Jung;Kim, Ik-Hwan;Kang, Jae-Seon
    • Molecular & Cellular Toxicology
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    • v.5 no.1
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    • pp.83-87
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    • 2009
  • In this study, we assessed the stability and toxicological safety of Angelica gigas Nakai (A. gigas Nakai) extract, which is comprised of decursin and decursinol angelate (D/DA). D/DA was tested for mutagenicity using Ames Salmonella tester strains (TA102, TA1535, and TA1537) with or without metabolic activation (S9 mix). No increase in the number of revertants was observed in response to any of the doses tested (1.25, 12.5, 125, and $1,250{\mu}/mLg$). In addition, a chromosome aberration test was conducted in the Chinese hamster lung (CHL) cell line. To accomplish this, cells were treated with D/DA (3.28, 13.12, 52.46, and $209.84{\mu}g/mL$) or with Mitomycin C ($0.1{\mu}/mLg$) as a positive control in the case of no metabolic activation or benzo(a)pyrene ($20{\mu}g/mL$) in the case of metabolic activation. No significant increase in chromosome aberrations was observed in response to treatment with any of these concentrations, regardless of activation of the metabolic system. According to these results, we concluded that D/DA did not induce bacterial reverse mutation or clastogenicity in vitro in the range of concentrations evaluated in these experiments.

An Analysis of the Physician Productivity in General Hospitals (전국 종합병원 의료인력의 생산성분석)

  • Lee, Jung-Un;Lee, Ki-Hyo;Moon, Ok-Ryun
    • Journal of Preventive Medicine and Public Health
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    • v.24 no.3 s.35
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    • pp.400-413
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    • 1991
  • The purpose of this paper is to identify factors affecting the optimum mix of required inputs and other relevant factors which account for the variation in physician's productivity in general hospitals, and to find out their implications for the efficient health planning and management. An extended version of Cobb-Douglas production function and cross sectional data of one day patient census from all general hospitals in Korea in 1988 were used in the analysis. Main results of the analysis and their implications could be summarized as follows : (1) The production function for physician's inpatient service shows the evidence of economies of scale, but the production function for physician's outpatient and adjusted-patient service, which combines both out- and in-patient service, shows that of dis-economies of scale. (2) The physician's role for production for all service is smaller than auxiliary personnel's, which imply that more intensive utilization of nurses, nursing aides and other auxiliary personnel is desirable for improving general hospital productivity (3) In case of physician's inpatient and adjusted-patient service, nurses' role is greater than nursing aides'. Therefore, more extensive utilization of nurses is recommended for the efficient operation of general hospitals. (4) The factor of hospital beds plays the leading role among required inputs in the production for physician's in- and adjusted-patient service. (5) The physician's productivity of general hospitals in rural area is lower than that in urban area. And the productivity of teaching hospitals is lower than that of the other hospitals. Further analysis was made in physician production function based upon the size of hospitals, namely those hospitals below 250 beds and those above. Explained variances by the factor of hospital beds was significantly increased in the case of those hospitals above 250. A more detailed and thorough investigation is needed for verifying factors influencing physician's productivity in general hospitals in Korea.

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Design of Image Rejection SSB Modulator for X-Band Monopulse RADAR using Waveguide Hybrid Coupler (도파관 하이브리드 커플러를 이용한 X-대역 모노펄스 레이더용 이미지 제거 SSB 변조기 설계)

  • Koh, Young-Mok;Ra, Keuk-Hwan
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.48 no.6
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    • pp.34-40
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    • 2011
  • From the present paper researched about the Design of Image Rejection SSB Modulator for X-Band Monopulse RADAR using Waveguide Hybrid Coupler. Generally, SSB modulator mixes IF(RF) and LO signals, and then it converts to RF(IF) frequency band. In this case, in order to transmit one sideband from RF band, SSB modulator is demanded the removal of image and LO signal. The balanced mixer was designed using waveguide hybrid coupler and crystal mixer diode to mix LO and IF signal. And also the IF Amplifier was designed for IF(+) and IF(-) signal generation which have $90^{\circ}$ phase differences which are suitable in two crystal mixer diode inputs. In order to maintain a high electric reliability from high frequency band the waveguide and IF amplifier's case were manufactured with aluminum using deep brazing techniques. The test result of SSB modulator, LO and sideband signal rejection ratio were 14.2dB and 18.5dB respectively.