• Journal of agriculture & life science
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• v.46 no.5
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• pp.73-82
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• 2012

Allele information from the analysis of the 13 microsatellite (MS) markers, were classified into the $F_0$, $F_1$ and $F_2$ generations, and probabilities of the same individual emergency in each generation was calculated. As a result, the 13 MS markers showed an estimate of $3.84{\times}10^{-23}$ on the premise of the randomly mated group of $F_2$, which implies that the same individuals may emerge by the use of 37 kinds of SNP markers. In this study, the experimental pigs were intercross between only 2 breeds (Korean native pig and Landrace). In addition, the success rate of paternity tests was analyzed on the whole group, by the use of the 13 MS markers and 37 SNP markers. As regards the exclusionary power of the second parent ($PE_{pu}$), MS markers and SNP markers showed 0.97897 and 0.99149, respectively. In relation to the parent exclusion power of both parent (PE), MS markers and SNP markers showed 0.99916 and 0.99949, respectively. In the case of the estimate to identify parental candidates that had the highest probability ($PNE_{pp}$), the two showed 1.00000 all. The Korean pig industry tends to mass produce hogs with limited numbers of alleles in limited parents. Such being the case, there is a need to organize a marker, for which it is imperative to find markers with high efficiency and high economic feasibility of the characteristics of DNA markers, sample size, the accuracy and expenses of genotyping cost, the manageability of data and the compatibility among analysis systems.

• Animal cells and systems
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• v.8 no.1
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• pp.41-47
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• 2004

The kallikrein-kinin system affects regulation of blood pressure, and genes encoding for the components of this system have been considered as good candidates for hypertension. To evaluate the relationship between genetic polymorphisms of candidate genes involved in this system and hypertension, we performed case-control studies using genetic markers in Korean normotensives and hypertensives, respectively. By association study, there was a marginal association with hypertension in AA genotype distribution of A1789G polymorphism in the hKLK1 gene (P=0.0754). Thus, this genetic polymorphism may weakly contribute to the susceptibility to hypertension in Koreans. We also observed that significant linkage disequilibrium exists among three polymorphic sites in the hKLK1 gene studied, suggesting that the three genetic polymorph isms can be useful as genetic markers in clinical association studies. Further studies using larger sample sizes and more genetic markers will be needed to clarify genetic influence of kallikrein-kinin system for hypertension.

• Journal of Korean Neurosurgical Society
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• v.62 no.4
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• pp.487-491
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• 2019

Conservative therapy with appropriate antibiotics is essential for most patients with infectious spondylitis. Although most antibiotics do not cause problems if it used properly and serious side effects are rare, side effects can occur with any class of drugs and adverse reactions of antibiotics can range from mild allergic reactions to serious and fulminant adverse events. These side effects are also extremely variable from patient to patient and from antibiotic to antibiotic. A side effect of antibiotics may paradoxically increase inflammatory marker levels. Here, the author presents two cases of antibiotic-induced increase in inflammatory markers in cured infectious spondylitis. The patients were successfully treated after stopping the antibiotic therapy. The differential diagnosis between antibiotic side effects and infection should be considered very carefully because the treatment is completely different. Although the exact mechanisms underlying successful treatment without antibiotics are unclear, we should consider the side effects of antibiotics when following inflammatory markers during treatment of infectious spondylitis.

• Proceedings of the Korean Society for Language and Information Conference
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• 2007.11a
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• pp.57-66
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• 2007

Case markers in Korean are omissible in colloquial speech. Previous discourse studies of Caseless bare NPs in Korean show that the information structure of zero Nominative not only differs from that of overt Nominative but it also differs from that of zero Accusative in many respects. This paper aims to provide a basis for these semantic/pragmatic properties of Caseless NPs through the syntactic difference between bare subjects and bare objects: namely, the former are left-dislocated NPs, whereas the latter form complex predicates with the subcategorizing verbs. Our analysis will account for the facts that (i) the distribution of bare subject NPs are more restricted than that of bare object NPs; (ii) bare subject NPs must be specific or topical; (iii) Acc-marked NPs in canonical position tend to be focalized.

• Korean Journal of Veterinary Research
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• v.52 no.2
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• pp.147-151
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• 2012

Radiography, ultrasonography with hydrogram, and contrast studies using radiopaque markers were applied to evaluate alimentary lymphoma in two cats. The hydrogram facilitated the differentiation of pseudo-thickening from true wall thickening, and enabled an evaluation of wall layering and lymph nodes. In case 1, mechanical obstruction of the duodenum was confirmed with barium-impregnated polyethylene spheres (BIPS), a radiopaque marker; however, results obtained in case 2 were not as definitive. We expect that hydrograms and BIPS can be used as valuable alternative methods to evaluate the gastrointestinal (GI) tract although further studies in cases involving GI tumors are needed.

• Journal of Korean Society on Water Environment
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• v.23 no.3
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• pp.391-396
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• 2007

Dry washing by air and sand to clean dishes was investigated for establishing a dry washing process in a kitchen. Thirty seasonings and foods as dirt markers and fourteen kinds of dishes were used for the experiment, and washing efficiency was evaluated by COD-MN (mg/L). It was found that air dry washing effectively reduced COD-MN of some dirt markers but not effective at all to some dirt markers. It could be also said that dirt markers would not be completely removed by air dry washing. The shape of dishes also affected COD-MN reduction by air dry washing. Sand dry washing showed excellent efficiency on COD-MN reduction. Combination of air and sand dry washing may be necessary to make a dish dry washing system which is completely independent from water.

• Biomedical Science Letters
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• v.28 no.3
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• pp.157-169
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• 2022

DNA typing is the typical technology in the forensic science and plays a significant role in the personal identification of victims and suspects. Short tandem repeat (STR) is the short tandemly repeated DNA sequence consisting of 2~7 bp DNA units in specific loci. It is disseminated across the human genome and represents polymorphism among individuals. Because polymorphism is a key feature of the application of DNA typing STR analysis, STR analysis becomes the standard technology in forensics. Therefore, the DNA database (DNA-DB) was first introduced with 4 essential STR markers for the application of forensic science; however, the number of STR markers was expanded from 4 to 13 and 13 to 20 later to counteract the continuously increased DNA profile and other needed situations. After applying expanded STR markers to the South Korean DNA-DB system, it positively affected to low copy number analysis that had a high possibility of partial DNA profiles, and especially contributed to the theft cases due to the high portion of touch DNA evidence in the theft case. Furthermore, STR marker expansion not only contributed to the resolution of cold cases but also increased kinship index indicating the potential for improved kinship test accuracy using extended STR markers. Collectively, the expansion of the STR locus was considered to be necessary to keep pace with the continuously increasing DNA profile, and to improve the data integrity of the DNA-DB.

• Fashion & Textile Research Journal
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• v.8 no.3
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• pp.303-309
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• 2006

This study intended to compare and analyze marking efficiencies of basic slacks, based on different cloth and production conditions, the width of cloth, the number of marking pieces and the direction for marking deployment and proposed an efficient marking method. The results were as follows. On the whole, the marking efficiencies increased with increasing cloth widths. In the case of small number of marking pieces, the efficiency increased with increasing cloth widths, while, for large number of marking pieces, there was no differences in the efficiency with the cloth widths. From the result of the comparison of the marking efficiencies with the number of marking pieces, it was shown that, in the case of small cloth width, the efficiency increased considerably with increasing number of marking pieces, while, in the case of large cloth width over two markers, there was no distinct effect of the number of markers on the marking efficiency. Thought there were some differences of the marking efficiencies with the marker directions, bi-direction marker was the most efficient marker, followed by one-direction for each size marker and one-direction marker.

• Speech Sciences
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• v.13 no.3
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• pp.207-219
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• 2006

The present study was designed to investigate the comprehension of 'who' and 'what' questions in 2- to 3-year-old normal children. Sixty children were divided into 3 groups depending on their ages, i.e., age groups 2;6-2;11, 3;0-3:5, and 3;6-3;11. Three types of 'who' questions and 2 types of 'what' questions were generated depending on the attached case markers, i.e., who-nominative, who-accusative, who-dative, what-nominative, and what-accusative. The children watched 36 cuts of short video recordings. After watching each cut, they were asked to answer one of the 5 types of wh-questions. For the 'who-nominative' and 'what-accusative' questions, even the late 2-year-old children performed with over 70% of accuracy, and the late 3-year-old children performed with over 95% of accuracy. For the 'who-accusative' and 'who-dative' questions, the late 2-year olds exhibited difficulty in comprehension with performance accuracy of 41% and 33%, respectively. However, the late 3-year olds could comprehend those questions correctly with over 90% of accuracy. On the other hand, in answering 'what-nominative' questions, the children did not show rapid development across the age groups, as the mean performance accuracies of the 3 groups were 39%, 49%, and 59%, respectively. The results indicated that children's understanding of a wh- question is largely affected by the case of the interrogative.

• Obstetrics & gynecology science
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• v.61 no.6
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• pp.698-701
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• 2018

We report a rare case of vaginal amelanotic melanoma. Malignant melanomas are cutaneous and extracutaneous tumors that arise from embryological remnants of neural crest cells/melanocytes. Amelanotic melanomas at such rare locations can be misdiagnosed both clinically and radiologically. Therefore, histopathological examination and immunohistochemistry are mandatory for the diagnosis of these tumors. We diagnosed this case using histopathology and confirmed the diagnosis based on the presence of immunohistochemical markers human melanoma black 45 (HMB45) and S-100.