• 제목/요약/키워드: Case Studies

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중국에서의 파킨슨병 침치료 임상연구 동향 (Acupuncture for Parkinson's Disease in China)

  • 김락형;장인수;강세영
    • Korean Journal of Acupuncture
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    • 제28권4호
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    • pp.147-158
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    • 2011
  • Objectives : The purpose of this study was to obtain some knowledge about the acupuncture treatments on Parkinson's disease for the future practice and the research from the clinical studies in China. Methods : The literatures were searched using the data base-China Academic Journals (CAJ) (1994-2011). Clinical studies of acupuncture for Parkinson's disease such as randomized controlled trial (RCT), non-randomized controlled trial (NRCT), case series, case report were included. Results : Of 145 articles, 52 Clinical studies met our inclusion criteria: 20 RCTs, 7 NRCTs, 22 case series and 3 case reports. Various kinds of acupuncture treatments such as scalp acupuncture, body acupuncture, abdominal acupuncture, acupoint injection, eye acupuncture and thick needle acupuncture (粗鍼) were used in the clinical studies. The treatment and control groups take Madopa Tablet (Levodopa + Benserazide HCl) in the same time in many studies, and Madopa treatment was used as a comparative treatment in the most of studies. Acupuncture treatment was done daily or 2~3 times a week for 2~20 weeks. All of studies reported high effective rate in the treatment group compared to control group. Conclusions : The results of this study could be used for the future study about the acupuncture therapy for Parkinson's disease.

동결견의 화침치료에 대한 임상논문 고찰: 중국논문을 중심으로 (A Review of Fire Needling on Frozen Shoulder: Focusing on Chinese Journals)

  • 이지수;유춘길;정성식;문성일
    • Journal of Acupuncture Research
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    • 제30권3호
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    • pp.87-99
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    • 2013
  • Objectives : The objective of this study is to find out the method and effects of fire needling on frozen shoulder in China. Methods : We searched journals using the China National Knowledge Infrastructure(CNKI) and PubMed. The keywords were a combination of "fire needling", "fire needle", "burning acupuncture", "frozen shoulder", "adhesive capsulitis", "periarthritis". Results : There were 23 studies finally selected, 7 were case control studies and 16 were case series studies. There were 9 out of 14 main meridians and 31 kinds of acupoints. The most frequently adopted meridians were LI, SI and TE. The most frequently used acupoints were $LI_{15}$, $SI_9$ and $TE_{14}$. Adjacent points were used more often than distant points. They usually heated the needle before insertion and needle retention was mostly not done. 7 case control studies showed that fire needling reported better results than the filiform needle or electro-acupuncture treatment. 15 case series studies reported a significant improvement in fire needling on frozen shoulder patients. Conclusions : There have been many studies regarding fire needling on frozen shoulder in China. Further studies should be required and these can be applied to clinical practices in Korea.

황련해독탕약침 치료에 대한 임상 논문 고찰: 국내 학술지의 증례보고와 대조군 연구 중심으로 (An Intensive Review On Clinical Thesis about Hwangryunhaedok-tang Pharmacopuncture Treatment: Focused on Case Reports and Controlled Studies in Korean Academic Journals)

  • 이수환;김순중
    • 한방재활의학과학회지
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    • 제29권2호
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    • pp.171-188
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    • 2019
  • Objectives The purpose of this thesis is to compare and analyze outcomes of case studies and controlled studies about Hwangryunhaedok-tang (HHT) pharmacopuncture in clinical studies. Based on these studies reporting clinical effects by using HHT pharmacopuncture, we object to deduct the comparative review in applying clinical disorders limitedly. And conclusionally, by using this comparative review, we aim to make the fine evidence in treating clinical specific diseases. Methods We searched 106 studies about HHT pharmacopuncture from 6 Korean web databases by using in Korean word 'Hwangryunhaedok-tang pharmacopuncture'. This search had been progressed throughout 1 month (January, 2019). There was 106 thesis and we excluded studies that are not related to HHT pharmacopuncture, experimental research, not the case report or randomized controlled trials, non-randomized controlled trials, not using HHT pharmacopuncture, not using only one pharmacopuncture, and not using HHT pharmacopuncture for major treating method. As a result, 39 thesis are selected as a population. Results We analyzed 34 case reports and 5 controlled studies. As the final outcome, HHT pharmacopuncture was used in musculoskeletal diseases, dermatopathy, and 32 specific diseases. Conclusions After analyzing 39 studies, effective symptom changes clinically and statistically by using HHT pharmacopuncture herbal acupuncture were identified. However, these thesis designs were reported deficiently in many parts such as not excluding other confounding variables. After modifying defects of thesis design and conduct study, it can play a role as the evidence using HHT pharmacopuncture more precisely.

최근 10년간 국내 뜸관련 연구에 대한 고찰 (The Review on the Domestic Studies of Moxibustion)

  • 신정미;강미숙;송호섭
    • Journal of Acupuncture Research
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    • 제26권5호
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    • pp.117-125
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    • 2009
  • Objectives : This study is to research the trend of the Moxibustion-related studies and to establish the hereafter direction for the study on Moxibustion. Methods : We reviewed the domestic articles published last ten years(2000~2009). Results : We have searched 45 articles in 4 journals of Korean Acupuncture & Moxibusion, Korean Oriental Medicine, Korean Meridian & Acupoint, Korean Oriental Internal Medicine. 1. There were the most research done 2003, 2008. Both of them have 8 articles. In other years there were 2 or more articles. 2. The pattern of study was as follow: the clinical studies were 23, studies of phisical Characteristics and new moxibustion method were 9, the philological study were 5, the reviewed studies were 3, the experimental studies were 2 and the others were 5. The rate of clinical studies was increased. 3. In the clinical studies, the case-control study and non case-control study were more than case study. The disease after stroke were the most predominant. The rates of direct moxibustion and indirect moxibusion were similar. 4. After beginning 2000s, there were more studies of thermodynamic Characteristics. In the mid 2000s, there were more studies of new moxibustion method appearing. Conclusions : We need more studies about various kinds of diseases, side effect and aftereffects. There should be convenient and useful methods of moxibustion.

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국내 학술지에 게재된 증례 연구 분석을 통한 산후풍의 한의학적 치료에 대한 고찰 (A Review on Sanhupung Treatment in Korean Medicine by Analyzing Case Studies Published in Korean Journal)

  • 황수인;이희윤;윤영진;박장경
    • 대한한방부인과학회지
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    • 제34권4호
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    • pp.131-150
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    • 2021
  • Objectives: The purpose of this study is to analyze the domestic study trends on Korean medicine treatment of Sanhupung. Methods: Case studies applying Korean medicine treatment on Sanhupung were searched through 5 domestic journal databases. General characteristics, interventions, outcomes, and results of the selected studies were analyzed. Also, the quality of the case studies was reviewed based on the CAse REport (CARE) guideline and Joanna Briggs Institute (JBI) critical appraisal checklist. Results: 11 studies (16 cases) were found to be analyzed according to their general characteristics, symptoms, interventions, treatment period, outcome, and results. The most common complaint of Sanhupung patients was pain, and the most applied intervention for Sanhupung was herbal medicine and acupuncture. The duration of treatment ranged from 9 days to 4 months. All case studies reported that the Korean medicine treatment was effective in treating Sanhupung. According to the quality assessment, 'Timeline of case', 'Diagnostic challenges', 'Intervention adherence and tolerability', 'Adverse and unanticipated events', and 'Informed consent' were showed low reporting rates. Conclusions: Further clinical studies are needed to establish the evidence for Korean medicine treatment for Sanhupung.

Adjusting sampling bias in case-control genetic association studies

  • Seo, Geum Chu;Park, Taesung
    • Journal of the Korean Data and Information Science Society
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    • 제25권5호
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    • pp.1127-1135
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    • 2014
  • Genome-wide association studies (GWAS) are designed to discover genetic variants such as single nucleotide polymorphisms (SNPs) that are associated with human complex traits. Although there is an increasing interest in the application of GWAS methodologies to population-based cohorts, many published GWAS have adopted a case-control design, which raise an issue related to a sampling bias of both case and control samples. Because of unequal selection probabilities between cases and controls, the samples are not representative of the population that they are purported to represent. Therefore, non-random sampling in case-control study can potentially lead to inconsistent and biased estimates of SNP-trait associations. In this paper, we proposed inverse-probability of sampling weights based on disease prevalence to eliminate a case-control sampling bias in estimation and testing for association between SNPs and quantitative traits. We apply the proposed method to a data from the Korea Association Resource project and show that the standard estimators applied to the weighted data yield unbiased estimates.

공사비 유형의 유치권 소송에 대한 중·소기업 건설업체 사례분석 (Case Study of Small and Medium-Sized Construction Firms on the Cost Type Lien Suits)

  • 윤하정;김주형;김재준
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2011년도 추계 학술논문 발표대회
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    • pp.137-138
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    • 2011
  • Mainly in construction liens to four contractors do not receive your order is caused by construction. This construction does not receive construction compunction to protect the contractor, I guess. On the other hand, the medium and small construction companies and contractors that could threaten the order four can be a problem. In this study, small construction companies to the lien of the lien claim on the issue of case studies have looked for the study. Small construction companies, in your case through the litigation between the lien of the lien litigation perspective, the cause of four orders after the analysis step by step construction was listed in chronological order. Identifying problem was the result of a lien. This study to previous studies regarding the lien on the issue through case studies of one kind of lien was derived for the problem. A follow-up studies and more case studies and interviews are considered necessary in the study.

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틱장애에 대한 한약 대조군 연구의 최근 동향;2007년 중국 임상 논문에서 (Herbal Medicine Treatment of Tic Disorder in Traditional Chinese Medicine : A Review Study)

  • 강문수;조이현;김락형
    • 동의신경정신과학회지
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    • 제19권2호
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    • pp.141-149
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    • 2008
  • Objective : This study was designed to analyze the herbal medicine case-control studies of tic disorder in traditional chinese medicine. Method : For this study, we searched the studies on tic disorder, which had been published 2007, through web-site CNKI(中國知識基魔設施工程) http://www.cnki.net). There were 15 herbal medicine case-control studies and we focused on those studies. Results: 1. DSM-IV(7 studies), CCMD(5 studies) and ICD-10(3 studies) were frequently used in the diagnosis of tic disorder. 2. Paeonia radix alba, Uncariae ramulus et uncus and Glycyrrhizae radix were frequently used in treatment. Moreover Scorpio, Gastrodiae rhizoma, Pinelliae rhizoma and so on were used. 3. Treatment results were assessed by improvement of symptom, YGTSS and so on. 4. Herbal medicine treatment was more effective than western medicine treatment in most studies, and side effects of herbal medicine were far less than those of western medicine. Conclusion : There have been reported many herbal medicine treatment studies of tic disorder in traditional chinese medicine. We believe that these studies can be applied to the clinical practices in Korean medicine.

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만성 경막하 혈종(Chronic Subdural Hematoma)의 한의 치료에 대한 최신 임상연구 동향 - CNKI 검색을 중심으로 - (A Review of Recent Korean Medicine Treatment for Chronic Subdural Hematoma Using the CNKI Database)

  • 제유란;김경림;황원덕
    • 대한한방내과학회지
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    • 제42권3호
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    • pp.308-322
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    • 2021
  • Objectives: This study investigates the latest clinical studies on Korean medicine treatment of chronic subdural hematoma (CSDH) in China. Methods: A CNKI search investigated the last 10 years of clinical studies of Korean medicine treatments in Chinese medical journals for CSDH. The search focused on authors, publication years, types of studies, purposes of studies, methods and duration of treatment, evaluation criteria, and results of treatment. Results: In 19 studies, there were 14 randomized controlled trials (RCTs), 4 case series, and 1 case-control study. In all 19 studies, Korean medical treatment and Western treatment were combined. Herbal medicine was used in 19 studies and acupuncture treatment in 2 studies. The most frequently used prescription was Hyeolbuchukeo-tang-gagambang, and the most frequently used acupoint was PC6. In all 19 studies, the effectiveness of Korean medicine treatment performed in parallel with Western treatment was confirmed. Conclusions: In this study, Korean medicine combined with Western treatment for CSDH was effective. More clinical studies and case reports are required to develop a guided treatment for CSDH.

한약을 이용한 아토피 임상연구의 경향에 관한 연구 (Overview for Pattern and Results of Herbal Medicine-derived Atopic Dermatitis Clinical Researches)

  • 김윤희
    • 대한한방소아과학회지
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    • 제26권2호
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    • pp.53-61
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    • 2012
  • Objectives To make comprehensive feature of clinical trials using herbal medicine and their results by today, then help a strategy for herbal medication-derived clinical studies in the future. Methods Through medical website (Pubmed EBSCO Medline), foreign clinical literatures about atopic dermatitis and herbal medicine were searched. And domestic clinical literatures about atopic dermatitis using internet website (OASIS) and hand-searching. Analysis was performed according to distribution mainly by subject, study design, number by year and its efficacy. Results and Conclusions Seventy-nine (Domestic literatures: Fifty, Foreign literatures: Twenty-nine) literatures were selected according to inclusion criteria of clinical study. 80% of domestic clinical literatures were observational studies, 50% of foreign were intervention. There were six adverse effect case studies, two follow-ups, one case report, four translational and four uncontrolled clinical trials in foreign literatures. And nineteen case reports, eighteen case series, two follow-up and five uncontrolled clinical studies in domestic. Six RCTs have established by four external herb therapy and two decoctions in Korea, showed positive effects. Three out of four external applications RCTs, four out of seven decoctions showed positive results in foreign studies. This study revealed the current status of atopic dermatitis clinical research using herbal drugs. To put clinical trials to use of herbal medicine in the treatment atopic dermatitis, scientific and objective-based studies should be needed.