• Genomics & Informatics
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• v.8 no.1
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• pp.9-18
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• 2010

Integrins are transmembrane receptor proteins that mediate cell-cell adhesion and cell-extracellular matrix (ECM) adhesion. The deregulation of cell-ECM adhesion and the abnormal expression of beta1 (${\beta}1$) integrins (ITGB1s) are involved in tumor development and metastasis. In the liver, the expression of integrins and ECM proteins can be a cause of hepatocellular carcinoma (HCC) development. We performed direct DNA sequencing of 24 individuals, and identified 23 sequence variants of ITGB1 polymorphisms. Among these 23 variants, 7 common variants were selected based on frequencies and linkage disequilibrium, and then genotyped in a larger-scale group of subjects (n=1,103). The genetic associations of ITGB1 polymorphisms with the clearance of HBV and HCC outcome of HBV patients were analyzed using logistic regression models and Cox relative hazard models. Although there was no significant association observed between the polymorphisms and the HCC outcome of HBV patients, the second most common haplotype (ITGB1 haplotype-2 [C-C-C-C-T-C-T]) was putatively associated with HBV clearance (OR=0.75, p=0.008 and $P^{corr}=0.05$). The minor allele frequency (MAF) of ITGB1 haplotype -2 of the spontaneously recovered (SR) group was significantly higher than that of the chronic carrier group (CC) (freq. = 0.248 vs. 0.199). The information derived from this study could be valuable for understanding the genetic factors involved in the clearance of HBV.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.3
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• pp.253-261
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• 2014

In this paper, vibration analysis of power differential gear train for 2.5MW wind turbine system is analyzed. which system is composed of two planetary gear set, one helical gear set and main shaft that connected by flange. Planetary gear set, helical gear set, main shaft are modeled in MASTA program and housing, torque arm, carrier, flange components are modeling by finite element method. Each models are combined by component mode superposition. To analysis of natural vibration characteristic about 2.5MW wind turbine gear train was performed and check about critical speed with wind load, mass unbalance, angle misalignment excitation frequency.

• Proceedings of the Korea Contents Association Conference
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• 2005.05a
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• pp.458-463
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• 2005

OFDM communication system is effective for the high data rate transmission in the frequency selective fading channel. Since OFDM has high PAPR, OFDM signal may be distorted by the nonlinear HPA. In this paper, we propose an combined SLM and PTS method for reducing the PAPR in OFDM communication system. Proposed method increased some system complex in comparison with exiting method. But we made sure of high efficiency in the case of reducing the PAPR. As a result of using the 16-QAM modulation and increasing the carrier number in the SLM, PTS method and the SLM-PTS combined method, SLM-PTS combined method is more an effective method of reducing 3.5 dB PAPR than exiting OFDM system when this method is M, L=3, D=128, 256 in 10-3 BER.

• Journal of Advanced Navigation Technology
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• v.14 no.2
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• pp.213-219
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• 2010

Recently, a multi-core system is studied for single terminal's operations on various service networks for mobile systems. Therefore, it is expected that mobile systems capable of supporting WCDMA, MC-CDMA, CDMA and WiBro would be developed. Mobile systems for supporting various service networks is able to be implemented on a single chipset via SoC(System one Chip) technology, thus a noble modem design proper for SoC technology is necessary. For high speed data transmission of 4G mobile communication services, OFDM scheme has to be applied. But, an OFDM signal consists of a number of independently modulated subcarriers, and superposition of these subcarriers cause a problem that can give a large PAPR. In this paper, a noble modem design for 4G mobile communication services and PAPR reduction method for solving the PAPR problem are proposed.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.3
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• pp.575-583
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• 2013

In ad hoc networks, a distributed timing synchronization is studied using a firefly-inspired approach. We illuminate the exiting synchronization algorithm based on the theory of pulse-coupled oscillators so that the algorithm can be applied to multi-carrier systems through packet-based communications, where nodes communicate over an orthogonal frequency-division multiple access air interface. As our main result, we introduce a new sync-code detector, which optimally designs both the coupling function and the detection threshold when various network parameters such as the number of nodes in the network and network topology are given a priori. Computer simulations are performed to show the convergence to a synchronized state in realistic network environments.

• Journal of Information Processing Systems
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• v.11 no.1
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• pp.57-75
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• 2015

In evaluating the performance of a dual-hop wireless link, the effects of large and small scale fading has to be considered. To overcome this fading effect, several schemes, such as multiple-input multiple-output (MIMO) with orthogonal space time block codes (OSTBC), different combining schemes at the relay and receiving end, and orthogonal frequency division multiplexing (OFDM) are used in both the transmitting and the relay links. In this paper, we first make compare the performance of a two-hop wireless link under a different combination of space diversity in the first and second hop of the amplify-and-forward (AF) case. Our second task in this paper is to incorporate the weak signal of a direct link and then by applying the channel model of two random variables (one for a direct link and another for a relayed link) we get very impressive result at a low signal-to-noise ratio (SNR) that is comparable with other models at a higher SNR. Our third task is to bring other three schemes under a two-hop wireless link: use of transmit antenna selection (TAS) on both link with weak direct link, distributed Alamouti scheme in two-hop link and single relay antenna with OFDM subcarrier. Finally, all of the schemes mentioned above are compared to select the best possible model. The main finding of the paper is as follows: the use of MIMO on both hops but application TAS on both links with weak direct link and the full rate OFDM with the sub-carrier for an individual link provide a better result as compared to other models.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.19 no.8
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• pp.1518-1527
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• 1994

An algorithm for BPSK demodulation of which channel is an electric distribution line is developed, and realized in this paper. To realize the BPSK demodulation by microprocessor, BPSK signal that is received through the distribution line must be converted to digital signal. A hardware which converts BPSK signal to digital one has been designed in this paper, and an algorithm for BPSK demoduation of which channel is distribution line has been also developed in algorithm for BPSK demoduation of which channel is distribution line has been also developed in this paper by paying the attention to the fact that a modulated point appears up and down according to the rising edge and falling edge of the modulated binary signal if the carrier frequency is even times to the modulated binary signal, and by paying the attention to the fact that the signal duration or modulated point is twice of the other point. The microprocessor demodulation system with the algorithm has been realized. The system proved to have 0.02%(or less) bit error rate in real BPSK demodulation.

• Korean Journal of Digital Imaging in Medicine
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• v.8 no.1
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• pp.51-55
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• 2006

The effects of Asaddition in amorphous selenium(a-Se) films for digital X-ray conversion material have been studied using the moving photocarrier grating(MPG) technique. This method utilizes the moving interference pattern generated by the superposition of the two frequency shifted laser beams for the illumination of the sample. This moving intensity grating induces a short circuit current, j$_{sc}$ in a-Se:As film. The transport parameters of the sample are extracted from the grating-velocity dependent short circuit current induced in the sample along the modulation direction. The electron and hole mobility, and recombination lifetime of a-Se films with arsenic(As) additions have been obtained. We have found an Increase in hole drift mobility and recombination lifetime, especially when 0.3% As is added into a-Se film, whereas electron mobility decreases with As addition due to the defect density. The transport properties for As doped a-Se films obtained by using MPG technique have been compared with X-ray sensitivity for a-Se:As device. The fabricated a-Se(0.3% As) device film exhibited the highest X-ray sensitivity out of 5 samples.

• Journal of the Korean Vacuum Society
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• v.16 no.4
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• pp.267-272
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• 2007

Al-doped ZnO (AZO) thin films were grown on glass substrates by radio-frequency magnetron sputtering. The effects of oxygen flow ratio, which was used for a sputtering gas, on the AZO thin films were investigated by using the X-ray diffraction (XRD), atomic force microscopy (AFM), and Hall effects measurement. The AZO thin film, deposited with oxygen flow ratio of 0% at the growth temperature of $400^{\circ}C$, showed a strongly c-axis preferred orientation and the lowest resistivity of $6.9{\times}10^{-4}{\Omega}cm$. The ZnO (002) diffraction peak indicated a tendency to decrease substantially with increasing the oxygen flow ratio. Furthermore, as the oxygen flow ratio was decreased, the carrier concentration and the hall mobility were increased, but the electrical resistivity was decreased.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.346-346
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• 2012

We investigated electrical and optical properties and chemical states of amorphous In-Ga-Zn-O (a-IGZO) thin films deposited at different substrate temperatures (from room temperature to $300^{\circ}C$). a-IGZO thin films were fabricated by radio frequency magnetron sputtering using $In_2O_3$ : $Ga_2O_3$ : ZnO = 1 : 1 : 1 target, and their electrical and optical properties and chemical states were investigated by Hall-measurement, UV-visible spectroscopy and x-ray photoelectron spectroscopy (XPS), respectively. The data showed that as substrate temperature increased, carrier concentration increased, but mobility, conductivity, transmittance in the shorter wavelength region (>350 nm), and the Tauc-plot-estimated optical bandgap decreased. XPS data indicated that the intensity of In 3d peak compared to Ga 3d peak increased but the intensity of Zn 3d peak compared to Ga 3d decreased, and that, from the deconvoluted O 1s peak, defects or oxygen vacancies and non-quaternary contents increased as the temperature increased. The relative intensity changes of the In, Zn, and O 1s sub-component are suggested to explain the changes in electrical and optical properties.