• Proceedings of the Korean Society for Applied Microbiology Conference
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• 2000.04a
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• pp.3-6
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• 2000

Antimicrobial resistance has been a well-recognized problem ever since the introduction of penicillin into clinical use. History of antimicrobial development can be categorized based on the major antibiotics that had been developed against emerging resistant $pathogens^1$. In the first period from 1940 to 1960, penicillin was a dominating antibiotic called as a "magic bullet", although S.aureus armed with penicillinase led antimicrobial era to the second period in 1960s and 1970s. The second stage was characterized by broad-spectrum penicillins and early generation cephalosporins. During this period, nosocomial infections due to gram-negative bacilli became more prevalent, while those caused by S.aureus declined. A variety of new antimicrobial agents with distinct mechanism of action including new generation cephalosporins, monobactams, carbapenems, ${\beta}$-lactamase inhibitors, and quinolones characterized the third period from 1980s to 1990s. However, extensive use of wide variety of antibiotics in the community and hospitals has fueled the crisis in emerging antimicrobial resistance. Newly appeared drug-resistant Streptococcus pneumoniae (DRSP), vancomycin-resistant enterococci (VRE), extended-spectrum ${\beta}$-lactamase-producing Klebsiella, and VRSA have posed a serious threat in many parts of the world. Given the recent epidemiology of antimicrobial resistance and its clinical impact, there is no greater challenge related to emerging infections than the emergence of antibiotic resistance. Problems of antimicrobial resistance can be amplified by the fact that resistant clones or genes can spread within or between the species as well as to geographically distant areas which leads to a global concern$^2$. Antimicrobial resistance is primarily generated and promoted by increased use of antimicrobial agents. Unfortunately, as many as 50 % of prescriptions for antibiotics are reported to be inappropriate$^3$. Injudicious use of antibiotics even for viral upper respiratory infections is a universal phenomenon in every part of the world. The use of large quantities of antibiotics in the animal health industry and farming is another major factor contributing to selection of antibiotic resistance. In addition to these background factors, the tremendous increase in the immunocompromised hosts, popular use of invasive medical interventions, and increase in travel and mixing of human populations are contributing to the resurgence and spread of antimicrobial resistance$^4$. Antimicrobial resistance has critical impact on modem medicine both in clinical and economic aspect. Patients with previously treatable infections may have fatal outcome due to therapeutic failure that is unusual event no more. The potential economic impact of antimicrobial resistance is actually uncountable. With the increase in the problems of resistant organisms in the 21st century, however, additional health care costs for this problem must be enormously increasing.

• Journal of Digital Convergence
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• v.14 no.4
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• pp.101-110
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• 2016

With the result of Korean national senior's real life state survey analysis that is triennially conducted based on Article 5 of Welfare of the Aged Act, this study categorized the senior according to age norm cognition, and figured out the characteristic of each category, and analyzed their needs for life satisfaction and hoping activities. Because the senior at present are on higher level of health, education, and economy than 20 to 30 years ago, it is about time to repeat discussion about the policies established in the past in terms of society, culture, industry, welfare, employment, and participation as a convergence approach. As a result of analysis study, the senior divided into three groups:, resignation type, progressiveness type, and saving appearances type. Their life satisfaction level and hoping activities by senior segment groups are different. By results of this study, the preservation of income for senior will be needed, and they don't want volunteer activities so that there are another policy system will be needed to vitalize senior's social participation for their healthy physical and mental life. Korean senior were satisfied with family members relationship, -although Korean senior's life satisfaction level is not higher so that the new policy to care senior by senior system will be reviewed more actively.

• Journal of Digital Convergence
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• v.14 no.11
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• pp.627-637
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• 2016

A Study on the Fear of Crime and Life Satisfaction: Focused on the mediating effect of interpersonal trust. The purpose of this study was to examine whether fear of crime accounts for life satisfaction, and the interpersonal trust mediating between fear of crime and life satisfaction. The subject of this study was a group of 557 adults above 20 years old in Seoul and Gyeonggi province. The survey was done from July 1st 2015 to August 31 2014. The results are summarized as follows: First, subjects who were women and had higher education showed higher life satisfaction. Second, fear of crime has statistically significant negative effects on life satisfaction. Third, fear of crime has statistically significant negative effects on interpersonal trust. Fourth, interpersonal trust has statistically significant positive effects on life satisfaction. Lastly, interpersonal trust acts as a mediator between fear of crime and life satisfaction. The implication of this study's results is for policy making and it is discussed to promote a higher level of interpersonal trust and increase the level of life satisfaction for residents.

• Journal of the Korea Computer Graphics Society
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• v.26 no.3
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• pp.111-121
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• 2020

Realistic training contents utilizing intensive immersion of virtual reality are being used in various fields such as industry, education, and medical care. High-risk, high-cost education training, in particular, is difficult to conduct in reality, but it can be applied with the latest virtual reality technology that enhances educational effectiveness by efficiently and safely experiencing it in an environment similar to reality. This study introduces a management system that systematically manages realistic virtual training contents and visualizes training results in schematic pictures based on defined evaluation elements. The management system can store the information generated from the content in the database and manage the training records of each trainee in a practical way. In addition, a content-based scenario can be created in multiple scenarios by setting training goals, number of participants, and methods for applying evaluation elements. This paper describes the management system's production method and the results based on the virtual reality training content as an application example.

• Journal of the Economic Geographical Society of Korea
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• v.1 no.1
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• pp.173-191
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• 1998

The Purpose of this study is to Present the tourism development Plan of Muan County in relation to the establishment of the Muau international Airport. This study criticizes the stereotypical tourism development plans carried out by numerous loyal self-governments. The highest purpose of tourism is to create an experience that cannot be had In a Person's daily life. Tourism development in Muan must be loyal to this philosophy of tourism. This study raises three key questions: What is the nature of tourism\ulcorner; For whom is tourism developed\ulcorner , Why is tourism being developed\ulcorner The answers to the three key questions are very basic ones. but are not being fulfilled in the tourism development of Korea, as fellows. Firstly, tourism development should be carried out to strengthen the special characteristics of tourism resources. Secondly, tourism development should encourage the participation of local residents within the Process, and it should be helpful to the local industry and the resident's income. lastly, the development should refrain from relying heavily on money-making businesses but seek to enrich the lives of visitors and hosts together. This study presents five distinctive tourism development schemes for Muan. They are as follows: the establishment of a scenic byway leading to the Airport: the development of Hoeshan lotus reservoir as a tourist resort for Buddhists and as a traditional health care center: the utilization of the .Japanese military airport relics as an historical and cultural tourist attraction: the establishment of a salt-water spa complex: and the vitalization of agricultural tourism by utilizing the advantage of the Muan international Airport.

• Journal of Internet of Things and Convergence
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• v.6 no.2
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• pp.65-72
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• 2020

The study aims to measure and analysis the spatial equity of Medical welfare facilities for older persons and services, and, based on this, to seek the plan to secure the fairness. To this end, the research was carried out by converging the studies of geography and regional development for the equity of social welfare studies and space arrangement on types and functions of Medical welfare facilities for older persons. The main results of the study showed that, first, in case of the spatial arrangement(desire-to-service), Medical welfare facilities for older persons are located in all areas of cities(Si) and counties(Gun) but mostly existing in cities. Second, in case of the equity of regional distribution of Medical welfare facilities for older persons, it can say the equity in Gun is higher than Si, comparing the regions of Si and Gun. Third, in case of spatial equity of sanatorium for older persons, the spatial equity of care facilities for older persons showed statistical difference depending on the time required to reach the facility, but no difference on distance. This study made various suggestions based on the results of the above research, and suggested the necessity of convergence studies grafting technologies such as AI and the Internet of Things.

• Journal of Digital Convergence
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• v.13 no.9
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• pp.439-444
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• 2015

This study analyzes the chicken-related prescription shown in the literature summarized by standing tradition deliberate aims to investigate the clinical efficacy of native chickens. Therefore, The old traditional medicine books of native chickens translate and organize the relevant prescriptions. The manuscript old documents is prescribed by the old central documents sourced directly from generation to generation descendants technical publishing contemporary situation sake of the development of this unique formulation not only contemporary who established himself through numerous trials and errors. Browse almost circular in traditional medicine prescription, which is scattered throughout the country is difficult, and because of the loss can not be confirmed even its existence. This study is to establish the analysis and separated by organized to establish a database on the basis of prescription and mixed herbs in a variety of functional foods developed through usability evaluation methods of treatment. Therefore, the management systems of native chickens related to lack of knowledge and information to foster the continued expansion and specialized training and knowledge of the future growth engine industry through the added value of cultural projects of national knowledge resources. Finally, convergence research and evaluate the usefulness of native chickens through interdisciplinary research systems, and practical measures of functional foods and alternative medicine are presented as well.

• Journal of Preventive Medicine and Public Health
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• v.34 no.1
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• pp.9-20
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• 2001

Objectives : To explore the relationship between Percutaneous Transluminal Coronary Angioplasty(PTCA) volume and the associated immediate outcome. Methods : A total of 1,379 PTCAs were peformed in 25 hospitals in Korea between October 8 and December 31 in 1997. Data from 1,317 PTCAs (95.5%) were collected through medical record abstraction. Inter-observer reliability of the data was examined using the Kappa statistic on a subsample of 110 PTCA procedures from five hospitals. Intra-observer reliability of the data was also examined. PTCA success and immediate adverse outcomes were selected as the outcome variables. A successful PTCA was defined as a case that shows less than 50% diameter stenosis and more than 20% reduction of diameter stenosis. Immediate adverse outcomes included deaths during the same hospitalization, emergency coronary artery bypass graft (CABG) within 24 hours after PTCA, and acute myocardial infarction within 24 hours after PTCA. The numbers of PTCAs performed in 1997 per hospital were used as the volume variables. Results : Without adjusting for patient risk factors that may affect outcomes, procedures at high volume hospitals ($\geq200$ cases per year) had a greater success rate (P=0.001) than low volume hospitals. There was a marginally significant difference (P=0.070) in major adverse outcome rates between high and low volume hospitals. After adjusting for risk factors, there were significant differences in procedural failure and major adverse outcome rates between high and low volume hospitals. Conclusions : After adjusting for patient clinical risk factors, the hospital volume of PTCA was associated with immediate outcomes. It is recommended that a PTCA volume per year be established in order to improve the immediate outcome of this procedure in Korea.

• Journal of Sensor Science and Technology
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• v.14 no.2
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• pp.69-77
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• 2005

The electronic nose (e-nose) has been used in food industry and quality controls in plastic packaging. Recently it finds its applications in medical diagnosis, specifically on detection of diabetes, pulmonary or gastrointestinal problem, or infections by examining odors in the breath or tissues with its odor characterizing ability. Moreover, the use of portable e-nose enables the on-site measurements and analysis of vapors without extra gas-sampling units. This is expected to widen the application of the e-nose in various fields including point-of-care-test or e-health. In this study, a PDA-based portable e-nose was developed using micro-machined gas sensor array and miniaturized electronic interfaces. The rich capacities of the PDA in its computing power and various interfaces are expected to provide the rapid and application specific development of the diagnostic devices, and easy connection to other facilities through information technology (IT) infra. For performance verification of the developed portable e-nose system, Six different vapors were measured using the system. Seven different carbon-black polymer composites were used for the sensor array. The results showed the reproducibility of the measured data and the distinguishable patterns between the vapor species. Additionally, the application of two typical pattern recognition algorithms verified the possibility of the automatic vapor recognition from the portable measurements. These validated the portable e-nose based on PDA developed in this study.

• Journal of the Korean association of regional geographers
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• v.20 no.2
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• pp.189-205
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• 2014

Most local governments make an attempt to attract tourists through the large-scale development projects or regional festival events. But, its possibility of success is actually low, so they must take care of ecotourism industry which has higher efficiency in comparison with investing expense. Seocheon area couldn't be focused greatly in spite of the excellent ecological and cultural resources. However, there are lots of possibilities to be a new center of ecotourism because of newly opened National Institute of Ecology and National Marine Biology Resource Institute. Therefore, the purposes of this thesis are to analyze several eco-cultural property all over Seocheon, introduce ecotourism, a main function of ecosystem services, and develop the program satisfying 3 elements of ecotourism; natural environment, visitors and residents. In Seocheon located in where the sea meets the river, ecological property could be reorganized into 4 areas in relation to existing famous tourist attractions. As a measure to let visitors stay, we induced them to lodge in the region through the field work. To realize slow life, we designed it so that they can enjoy each landscape slowly. we also suggested the program which can guide visitors onto the vicinity of habitat for migratory birds at the mouth of Geumgang River and Seocheon foreshore nominated as Ramsar wetlands by focusing on National Institute of Ecology and National Marine Biology Resource Institute which will be the Mecca of ecology research. Through this research, there will be an opportunity to satisfy visitors of Seocheon and enrich local residents' lives.