• Title/Summary/Keyword: Capsules

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Design and fabrication of capsules with isotropic destruction intensity (등방 파괴 강도를 갖는 캡슐 설계 및 제작)

  • Lim, Tae-Uk;Cheng, Hao;Hu, Jie;Wang, Shu-Le;Jung, Won-Suk
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2022.04a
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    • pp.247-248
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    • 2022
  • 3D printer-based self-healing capsules have been proposed to heal cracks by enabling various structural designs, repeatable fabrication, and strength analysis of the capsules. The Fusion Deposition Modeling (FDM) method was used to design, analyze, and produce new self-healing capsules that are widely used at low cost. However, PLA extruded from FDM has low interlayer adhesion energy, and thus strength varies depending on the angle of load applied to the laminated layer and the concrete structure, thereby degrading the performance of the self-healing capsule. Therefore, in this paper, the structure of the capsule manufactured by the FDM PLA method has isotropic strength was designed. In addition, the fracture strength in the x, y, and z directions of the load applied through the compression test was analyzed. As a result, it was confirmed that the newly proposed capsule design has an isotropic fracture strength of 1400% in all directions compared to the existing spherical thin-film capsule.

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Depositions of Egg Capsules by Female Shell Heights and Comparisons of Sizes at 50% of Group Sexual Maturities of the Female Rapa Whelk Rapana venosa in Three Different Salinity Concentration Regions

  • Lee, Il Ho;Chung, Ee-Yung;Son, Pal Won;Lee, Ki-Young
    • The Korean Journal of Malacology
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    • v.30 no.2
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    • pp.139-153
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    • 2014
  • We investigated fecundities in egg capsules and sizes at 50% of group sexual maturities in female Rapana venosa in three different salinity concentration regions (S-1, S-2, and S-3). In three different salinities, egg capsule heights, the number of egg capsules and the number of eggs and embryos were remarkably increased with the increase of female shell heights (or ages) and also increased with the increase of salinity concentrations. Heights of egg capsules, the number of egg capsules and fecundities (the number of eggs and embryos) were the maximum at S-1 (Gwangyang Bay (average 31.5 psu)) and the minimum at S-3 (the upper reaches of Seomjin River (average 15.5 psu)). Total numbers of fecundities of R. venosa $individual^{-1}year^{-1}$ were about $1{\times}10^6$ at S-1 region, about $8{\times}10^5$ at S-2 region, and about $2{\times}10^5$ at S-3 region. Rates (50%) of individuals reaching first sexual maturities in three different salinity regions (S-1, S-2 and S-3) were over 50% in females measuring 7.1-8.0 cm in shell height (considered to be two years old), and 100% in those > 10.1 cm (considered to be five years old). Biological minimum sizes ($RM_{50}$) in females in three different regions are 72.0 mm SH at S-1 region, 70.9 mm SH at S-2 region, and 74.6 mm SH at S-3 region, respectively. Exceptionally, smaller individuals (considered to be one year old) were participated in reproduction.

Various Types and Manufacturing Techniques of Nano and Micro Capsules for Nanofood

  • Kim, Dong-Myong
    • Journal of Dairy Science and Biotechnology
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    • v.24 no.1
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    • pp.53-63
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    • 2006
  • Nano and micro capsulation (NM capsulation) involve the incorporation for nanofood materials, enzymes, cells or other materials in small capsules. Since Kim D. M. (2001) showed that a new type of food called firstly the name of nanofood, which means nanotechnology for food, and the encapsulated materials can be protected from moisture, heat or other extreme conditions, thus enhancing their stability and maintaining viability applications for this nanofood technique have increased in the food. NM capsules for nanofood is also utilized to mask odours or tastes. Various techniques are employed to form the capsules, including spray drying, spray chilling or spray cooling, extrusion coating, fluidized bed coating, liposome entrapment, coacervation, inclusion complexation, centrifugal extrusion and rotational suspension separation. Each of these techniques is discussed in this review. A wide variety of nanofood is NM capsulated - flavouring agents, acids, bases, artificial sweeteners, colourants, preservatives, leavening agents, antioxidants, agents with undesirable flavours, odours and nutrients, among others. The use of NM capsulation for sweeteners such as aspartame and flavors in chewing gum is well known. Fats, starches, dextrins, alginates, protein and lipid materials can be employed as encapsulating materials. Various methods exist to release the ingredients from the capsules. Release can be site-specific, stage-specific or signaled by changes in pH, temperature, irradiation or osmotic shock. NM capsulation for the nanofood, the most common method is by solvent-activated release. The addition of water to dry beverages or cake mixes is an example. Liposomes have been applied in cheese-making, and its use in the preparation of nanofood emulsions such as spreads, margarine and mayonnaise is a developing area. Most recent developments include the NM capsulation for nanofood in the areas of controlled release, carrier materials, preparation methods and sweetener immobilization. New markets are being developed and current research is underway to reduce the high production costs and lack of food-grade materials.

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Reproductive Ecology of the Purple Shell , Rapana venosa (Gastropoda : Muricidae), with Special Reference to the Reproductive Cycle, Depositions of Egg Capsules and Hatchings of Larvae) (피뿔고둥 , Rapana venosa (Gastropoda : Muricidae)의 생식생태 , 특히 생식주기 , 난낭산출 및 유생부생)

  • Eu-Yung Chung;Sung-Yeon Kim
    • The Korean Journal of Malacology
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    • v.9 no.2
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    • pp.1-15
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    • 1993
  • The reproductive ecology of the purple shell, Rapana venosa was investigated by the histological observations on depositions of the egg capsules, and hatching of larvae in the laboratory and the subtidal zone of the vicinity of piung-do, Chollabud-do, west coast of korea, for one year from June 1992 to May 1993. The results are summarized as follows:1. Rapana venosa is dioecious in sex. The ovary is composed of a number of ovarian lobules, and the testis comprises a number of ovarian lobules, and the testis comprises of gonads could be classified into 4 stages in males and 5 stages in females: 1) growing stage(in female subdivided into 2 stages of early and late growing stage). 2)mature stage. 3)spent stage or copulationstage. 4)rdcovering stage. The early growing stage in females of the purple shell was in September through February, late gorwing stage was in October to March, mature stage was in September to January, mature stage was in September to July, copulation stage was in Februaty to June and recovering stage in April to October.3. Spawning occurred 3-4 times at intervals of 1-3 days, and completed within 10 days from the beginning of spawning during the spawning season of the year.4. From the results of laboratory and field observations, egg masses are composed of a number of egg capsules, egg masses are occurred from May to late August, and in mid August depositions of egg mass in composed of 90-113 egg capsules, fecundity in an egg capsule was ranged 984 to 1,241 eggs(average 1,096 egg). Therefore, fecundity in total egg capsules spawned per individual during the spawning season is estimated as approximately 320,000 to 450,000 egges.5. The incubation period during deposition of an egg capsule to hatching larvad tood 17 days at 18.3-20.4%C(water temperature)and 1.021 (specific gravity fo sea water).

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A histopathological study on porcine cysticercosis (돼지 유구낭미충증의 병리조직학적 관찰)

  • Shin, Tae-kyun;Kim, Seung-ho
    • Korean Journal of Veterinary Research
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    • v.33 no.3
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    • pp.465-469
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    • 1993
  • This paper dealt with the histopathological findings on the natural cysticercosis in pigs. Three cases of porcine cysticercosis, which had been kept in the Department of Veterinary Medicine, Cheju. University more than ten years, were histopathologically examined in order to see the host reaction to the parasite. Capsules containing scolex were mainly found in the fascia of skeletal muscle, heart, and brains. Microscopically, cysticerci in the epicardium and the fascia of skeletal muscles were encapsulated with fibroblasts and collagen fibers. Around capsules, there was infiltration of eosinophils, lymphocytes and macrophages, although the degree and severity of inflammatory reaction varied case by case. Cerebral cortex also had the inflammatory exudate of lymphoid cells in the vicinity of the scolex. whereas perivascular lymphocytic cuffings were commonly seen around capsules. GFAP immunoreactive fibers formed a limiting membrane along the outer side of capsules. There was also proliferation of GFAP-positive astrocytes encirling infiltrating lymphocytes around vessels. In the central nervous system, astrocytes and lympoid cells play an important role in the demarcation of cysts and local immunity, respectively. In conclusion, host tissue reaction in porcine cysticercosis seemed to vary significantly according to the affected organs of pigs. It is assumed that capsules containing worms seemed to be formed at early stage of cysticercosis.

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Preparation and Application of Charcoal-Encapsulated Methyl Silica Microcapsules (활성탄을 함유한 메틸실리카 마이크로캡슐의 제조 및 응용)

  • Ahn, Bok-Yeop;Lee, Yu-Mi;Ham, Myung-Kyung;Rhee, Dong-Seok
    • Journal of Industrial Technology
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    • v.23 no.A
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    • pp.199-206
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    • 2003
  • The charcoal-encapsulated methyl silica microcapsules were prepared by a O/W microemulsion sol-gel method, and the adsorption properties on aquatic humic acid were investigated. The capsules prepared were spherical, $100{\sim}1000{\mu}m$ in size. The size distribution was controllable by adjusting the size of charcoal powder, charcoal/methyl silica ratio, and agitating speed in O/W sol-gel process. Adsorption efficiency of charcoal for aquatic humic acid was decreased after encapsulation by methyl silica shell. The decreased adsorption efficiency can be dependent on the decrease of the BET surface area and pore volume after encapsulation. Diffusion properties of humic acid through the capsule shell also played an important role on adsorption efficiency. Therefore, the reasonable target pollutants for the capsules can be VOC or odor molecules which can overcome diffusion barrier through shell of capsules in air condition. Functionalization methods for the charcoal-encapsulated $CH_3(SiO)_n$ microcapsules by incorporation of $TiO_3$ as a phtocatalytic function and by incorporation of inorganic pigment as a color function were also investigated. $TiO_2$ coating properties were controllable by adjusting pH, temperature, and the concentration of $TiOSO_4$. In XRD measurement, the crystal form of the coated $TiO_2$ was anatase. For the colorization of the capsules, inorganic pigments were more efficient than organic dyes, and various color was introduced to the capsules using inorganic pigments.

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The Crack Healing Properties of Cement Mortar Materials Using Crystal Growth Type Self-Healing Solid Capsules According to the Crack Induction Age (균열 유도 재령에 따른 결정성장형 자기치유 고상캡슐 활용 시멘트 모르타르의 균열 치유 특성)

  • Choi, Yun-Wang;Nam, Eun-Joon;Kim, Cheol-Gyu;Oh, Sung-Rok
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.8 no.4
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    • pp.475-482
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    • 2020
  • In this study, three levels of solid capsules were prepared according to the composition ratio of core materials for the crystal growth type self-healing solid capsule, and a cement mortar was prepared with the crystal growth type self-healing solid capsule. The prepared solid capsule was mixed with 3% of the cement mass to evaluate the healing properties according to the crack induction age of the cement mortar. As a result of test, the crack healing properties according to the crack induction age of cement mortar mixed of solid capsules, it was confirmed that the self-healing performance of the cement mortar with the solid capsules was increased self-healing performance of 7 days than 28 days. This is because the unhydrated binder remains.

Resonance frequency analysis of 3D printed self-healing capsules for localization of self-healing capsules inside concrete using millimeter wave length electromagnetic waves (밀리미터 전자기파를 이용한 콘크리트 내부 자가치유 캡슐의 위치 측정을 위한 3D 프린팅 자가치유 캡슐의 공진 주파수 분석)

  • Lim, Tae-Uk;Cheng, Hao;Lee, Yeong Jun;Hu, Jie;Kim, Sangyou;Jung, Wonsuk
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2022.11a
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    • pp.243-244
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    • 2022
  • In this paper, experiments were conducted on signal amplification of polymer capsules for application to Ground Penetrating Radar so as to enable real-time monitoring of polymer capsules inside concrete using the Morphology Dependent Resonance phenomenon. A TEM CELL and a vector network analyzer were used to analyze the difference in resonance frequency depending on the material of the sphere and the presence or absence of fracture. In order to manufacture a capsule of a size that can be measured using millimeter waves used in GPR, we manufactured a capsule with a 3D printer and analyzed the effects of the presence or absence of coating and the size of the capsule on the resonance frequency. Resonant frequency or signal amplification is more affected by diameter than coating. The capsule showing the highest amplification is the resin-coated 50 mm diameter capsule with a 316-fold increase and the lowest capsule is the uncoated 10 mm diameter capsule with a signal amplification of 11.9 times. These results demonstrate the potential of GPR to measure the position and state of self-healing capsules, which are small-sized polymers, in real time using millimeter waves.

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Continuous Melatonin Attenuates the Regressing Activities of Short Photoperiod in Male Golden Hamsters

  • Choi, Donchan
    • Development and Reproduction
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    • v.17 no.2
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    • pp.111-119
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    • 2013
  • Golden hamsters reproduce in a limited time of a year. Their sexual activities are active in summer but inactive in winter during which day length does not exceed night time and environmental conditions are severe to them. The reproductive activities are determined by the length of light in a day (photoperiod). Melatonin is synthesized and secreted only at night time from the pineal gland. Duration of elevated melatonin is longer in winter than summer, resulting in gonadal regression. The present study aimed at the influences of continuous melatonin treatments impinging on the gonadal function in male golden hamsters. Animals received empty or melatonin-filled capsules for 10 weeks. They were divided into long photoperiod (LP) and short photoperiod (SP). All the animals maintained in LP (either empty or melatonin-filled capsules) showed large testes, implying that melatonin had no effects on testicular functions. Animals housed in SP displayed completely regressed testes. But animals kept in SP and implanted with melatonin capsules exhibited blockage of full regression by SP. These results suggest that constant release of melatonin prohibits the regressing influence of SP.

Dissolution Characteristics of Biphenyl Dimethyl Dicarboxylate from Solid Dispersions with Copolyvidone

  • Moon, Jee-Hyun;Chun, In-Koo
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1997.04a
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    • pp.118-118
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    • 1997
  • Solid dispersions were used to increase the dissolution rate of biphenyl dimethyl dicarboxylate (DDB) in water, with the ultimate goal of optimizing its bioavailability when incoporated into pharmaceuticals. Carriers used were Kollidon 30, Kollidon VA 64, 2-hydroxypropyl-${\beta}$-cyclodextrin (HPCD), sodium salicylate or sodium benzoate. DDB solid dispersions were prepared at drug to carrier proportions ranging from 1 : 5 to 1 : 20 (w/w) by solvent evaporation method. DDB tablets (7.5 mg) were prepared by compressing the powder mixture composed of solid dispersions, lactose, corn starch, crospovidone and magnesium stearate using a single-punch press. DDB capsules (7.5 mg) were prepared by filing the mixture into empty hard gelatin capsules (size #1). Dissolution studies of DDB from powdered solid dispersions, tablets and capsules were performed in 900 $m\ell$ of water at 100 rpm and 37$^{\circ}C$ by the paddle method. The dissolved amount was assayed by HPLC and expressed as the mean(%)of three determinations.

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