• Journal of the Korean Chemical Society
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• v.37 no.12
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• pp.1035-1046
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• 1993

Some iron(III)porphyrin complexes were prepared, and identified by the spectroscopic methods. Elution behavior of iron(III)porphyrin complexes was investigated by reversed-phase HPLC. The optimum conditions for the separation of iron(III)porphyrin complexes were examined with respect to flow rate and mobile phase strength. These complexes were successfully separated on NOVA-PAK $C_{18}$ column using methanol / water(95/5) for $[T_pCF_3PP)Fe(R)]$ and methanol / water (98/2) for $[(P)Fe(C_6F_5)]$ as a mobile phase. It was found that these complexes were largely eluted in an acceptable range of capacity factor value ($0{\leq}logk'{\leq}1$). The dependence of the capacity factor (k') on the volume fraction of water in the binary mobile phase as well as the dependence of k' on the liquid-liquid extraction distribution ratio$(D_c)$ in methanol-water / n-pentadecane extraction system showed a good linearity. It means that the retention of iron(III)porphyrin complexes on NOVA-PAK $C_{18}$ column is largely due to the solvophobic effect. Also, there was a good linear dependence of the capacity factor(k') on the column temperature and enthalpy calculated by van't Hoff plot. From these results, it was confirmed that the retention mechanism of iron(III)porphyrin complexes in reversed-phase liquid chromatography was invariant under the condition of various temperature, and the solvophobic binding process exhibited isoequilibrium behavior.

• Geomechanics and Engineering
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• v.27 no.5
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• pp.497-509
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• 2021

A large deformation FEM (Finite Element Method) based numerical analysis has been performed to study the behaviour of the bell-shaped anchor embedded in undrained saturated (cohesive) soil with the help of finite element based software ABAQUS. A typical model anchor with bell-diameter of 0.125 m, embedded in undrained saturated soil with varying cohesive strength (from 5 kN/m² to 200 kN/m²) has been chosen for studying the characteristic behaviour of the bell-shaped anchor installed in cohesive soil. Breakout factors have been evaluated for each case and verified with the results of experimental model tests for three different types of soil samples. The maximum value of breakout factor was found as about 8.5 within a range of critical embedment ratio of 2.5 to 3. An explicit model has been developed to estimate the breakout factor (F_c) for uplift capacity of bell-shaped anchor within clay mass in terms of H/D ratio (embedment ratio). It was also found that, the ultimate uplift capacity of the anchor increases with the increase of the value of cohesive strength of the soil and H/D ratio. The empirical equation developed in the present investigation is usable within the range of cohesion value and H/D ratio from 5 kN/m² to 200 kN /m² and 0.5 to 3.0 respectively. The proposed model has been validated against data obtained from a series of model tests carried out in the present investigation. From the stress-profile analysis of the soil mass surrounding the anchor, occurrence of stress concentration is found to be generated at the joint of anchor shaft and bell. It was also found that the vertical and horizontal stresses surrounding the anchor diminish at about a distance of 0.3 m and 0.15 m respectively.

• Structural Engineering and Mechanics
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• v.17 no.2
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• pp.167-186
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• 2004

The design load-carrying capacities of wooden shores depend on factors, such as the wood species and properties, and construction methods. This paper focuses on the construction methods, including an upright single shore, group of upright shores, group of inclined shores, butt connections and lap connections. This paper reports experiments to obtain critical loads and then developed an empirical equation based on Euler' formula for the critical loads and design load-carrying capacities. The test results show that the critical loads for an upright single wooden shore are greater than the average values for a group of upright shores, and the latter are greater than the average values for a group of inclined shores. Test results also show that the critical loads become smaller when butt or lap connections are used, butt connections possessing greater critical loads than lap connections. Groups of inclined shores are very popular at work sites because they have some practical advantages even though they actually possess inferior critical loads. This paper presents an improved setup for constructing groups of inclined shores. With this method, the inclined shores have larger critical loads than upright shores. The design load-carrying capacities were obtained by multiplying the average critical loads by a resistance factor (or strength reduction factor, ${\phi}$) that were all smaller than 1. This article preliminarily suggests ${\phi}$ factors based on the test results for the reference of engineers or specification committees.

• Structural Engineering and Mechanics
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• v.12 no.6
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• pp.615-632
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• 2001

Ductility of open piled wharves under reversed cyclic loads has been investigated. Experimental testing of five wharf models having a scale of about 1:4 was conducted under the application of horizontal reversed cyclic loading. The experiments were designed to focus on the horizontal ultimate load, ductility and failure mode of the considered wharf models. Nonlinear numerical analyses using the finite element method were also performed on numerical models representing the experimentally tested wharves. The results of the experimental tests showed that open piled wharves possessed favourable ductile behaviour and that their load bearing capacity did not depreciate until a ductility factor of 3 to 4 was reached. The numerical analysis showed that the relative rotation that took place at the joints between the steel piles and the R.C. beam was responsible for a considerable portion of the total horizontal deformation of the wharves. Therefore, it was concluded that introducing the joint stiffness in calculating the deformations of open piled wharves was important to achieve reasonable accuracy.

• Korean Journal of Soil Science and Fertilizer
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• v.6 no.1
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• pp.29-31
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• 1973

Upon the assumption that the available components in the soil evaluated by present analytical procedures, are as effective as the components applied to the soil as fertilizer, some formulas for the calculation of fertilizer requirements (F. R) for crops are suggested. Basically, the formulas are derived by combining the country average values of soil test data(${\overline{ST}}$) and of the optimum rate of fertilizers (ORF) for crops obtained from N.P.K. trials in farmer's field, as following. $$F.R(kg/10a)={\overline{ST}}(kg/10a)+ORFkg/10a-ST(kg/10a)$$ where, ST denotes the available components tested in the soil under question. Although this formula can be used both for P and K fertilizers, considering the significance of the potassium saturation rate of the soil for the availability of K, for the calculation of K fertilizer requirement, following formula is suggested. $$F.R(kg/10a)=(C.E.C.{\times}B.S.R.K.-KST(me/100g){\times}CF$$ where, B. S. R. K. is the basic potassium saturation rate of the soil and CF is conversion factor for the conversion of K me/100g into $K_2O$ kg/10a. The B. S. R. K. for different crops are obtained from the country average values of soil exchangeable K (${\overline{KST}}$), cation exchange capacity (CEC) and the optimum rates of K fertilizers for crops (ORF $K_2O$). $$B.S.R.K.=\frac{{\overline{KST}}{\times}CF+ORF(K_2O)}{CEC{\times}CF}$$ Using these formulas, equations for P and K fertilizer requirements for rice, barley, wheat, corn, italian millet, soy bean, sweet potato, potato and rape are derived.

• Applied Chemistry for Engineering
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• v.22 no.1
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• pp.114-118
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• 2011

Even though the carbon paste electrode bound with mineral oil is useful for research about the characteristics of enzymes, it remains far from practical uses because the lack of mechanical hardness limits its practical use. When the rubber liquefied in toluene was used as a binder of carbon powder in lab, it is confirmed that the mechanical robustness of the electrode is guaranteed. In order to confirm whether it shows quantitative electrochemical behaviors or not, its kinetic parameters, e.g. the symmetry factor (${\alpha}=0.28$), the exchange current density ($i_0=4.06{\mu}A/cm^2$), the capacity of the double layer ($C_d=2.11{\times}10^{-3}F$), the Michaelis constant ($K_M=2.45{\times}10^{-3}M$), and the time constant (${\tau}_B=0.077sec$) were investigated. Our experimental observations prove that the chloroprene rubber is a promising binder for the practical use of a carbon paste electrode.

• Journal of the Earthquake Engineering Society of Korea
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• v.16 no.4
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• pp.1-8
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• 2012

Domestic steel moment resisting frames were designed in accordance with the former KBC2005 and the current KBC2009, and then their seismic performance was evaluated in accordance with FEMA355F by utilizing nonlinear dynamic analysis. The results from the procedure in FEMA355F were different with those from the capacity spectrum method utilizing nonlinear static push-over analysis. In particular, the domestic steel moment resisting frames have a weak panel zone, so their behavior can be estimated more precisely by nonlinear dynamic analysis. The domestic steel moment resisting frames satisfied the performance goal if located at a site class $S_B$ or $S_C$, regardless of the story number and the response modification factor. However, if they are located at a site class $S_D$ or $S_E$, performance goal satisfaction cannot be guaranteed. No matter what standard is used for the design, KBC2005 or KBC2009, the domestic steel moment resisting frames may possess satisfactory seismic performance if the site condition is relatively good.

• Nutrition Research and Practice
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• v.10 no.5
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• pp.494-500
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• 2016

BACKGROUND/OBJECTIVES: Evidence indicates that berry anthocyanins are anti-atherogenic, antioxidant, and anti-inflammatory. However, berries differ vastly in their anthocyanin composition and thus potentially in their biological and metabolic effects. The present study compared hypolipidemic, antioxidant, and anti-inflammatory properties of blueberry (BB), blackberry (BK), and blackcurrant (BC) in a diet-induced obesity (DIO) mouse model. MATERIALS/METHODS: Male C57BL/6J mice were fed a high fat (HF; 35% fat, w/w) control diet or a HF diet supplemented with freeze-dried 5% BB, 6.3% BK or 5.7% BC for 12 weeks (10 mice/group) to achieve the same total anthocyanin content in each diet. Plasma lipids, antioxidant status and pro-inflammatory cytokines were measured. The expression of genes involved in antioxidant defense, inflammation, and lipid metabolism was determined in the liver, epididymal adipose tissue, proximal intestine, and skeletal muscle. Histological analysis was performed to identify crown-like structure (CLS) in epididymal fat pads to determine macrophage infiltration. RESULTS: No differences were noted between the control and any berry-fed groups in plasma levels of liver enzymes, insulin, glucose, ferric reducing antioxidant power, superoxide dismutase, and tumor necrosis factor ${\alpha}$. However, BK significantly lowered plasma triglyceride compared with the HF control and other berries, whereas BC significantly reduced F4/80 mRNA and the number of CLS in the epididymal fat pad, indicative of less macrophage infiltration. CONCLUSIONS: The present study provides evidence that BB, BK and BC with varying anthocyanin composition differentially affect plasma lipids and adipose macrophage infiltration in DIO mice, but with no differences in their antioxidant capacity and anti-inflammatory potential.

• Journal of the Korean GEO-environmental Society
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• v.15 no.4
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• pp.43-51
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• 2014

A Large-diameter drilled shaft of deep water depth composite foundation supporting a high rise pylon of the test designed super long span bridge was designed by allowable stress design method and failure probability through reliability analysis to bearing capacity was estimated. The allowable stress design results for the bearing capacity of a drilled shaft were analyzed by reliability analysis and the probability of failure shows 0.12 % in case of CFEM, 0.0002 % in case of Korea Highway Corporation criterion, and 0.003 % in case of structure foundation design criterion. In the allowable stress design, the bearing capacity of a large-diameter drilled shaft was obtained by applying to safety factor 3 and reliability analysis for the results was done. If the failure probability suggested by AASHTO(2007) specification is set to 0.02 %, the socketed length of a drilled shaft shows an increase of 25 % in CFEM, decrease of 60 % in KHCC, and decrease of 89 % in SFDC.

• Journal of Veterinary Science
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• v.24 no.3
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• pp.44.1-44.17
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• 2023

Background: Antibiotic resistance is a significant public health concern around the globe. Antimicrobial peptides exhibit broad-spectrum and efficient antibacterial activity with an added advantage of low drug resistance. The higher water content and 3D network structure of the hydrogels are beneficial for maintaining antimicrobial peptide activity and help to prevent degradation. The antimicrobial peptide released from hydrogels also hasten the local wound healing by promoting epithelial tissue regeneration and granulation tissue formation. Objective: This study aimed at developing sodium alginate based hydrogel loaded with a novel antimicrobial peptide Chol-37(F34-R) and to investigate the characteristics in vitro and in vivo as an alternative antibacterial wound dressing to treat infectious wounds. Methods: Hydrogels were developed and optimized by varying the concentrations of crosslinkers and subjected to various characterization tests like cross-sectional morphology, swelling index, percent water contents, water retention ratio, drug release and antibacterial activity in vitro, and Pseudomonas aeruginosa infected wound mice model in vivo. Results: The results indicated that the hydrogel C proved superior in terms of cross-sectional morphology having uniformly sized interconnected pores, a good swelling index, with the capacity to retain a higher quantity of water. Furthermore, the optimized hydrogel has been found to exert a significant antimicrobial activity against bacteria and was also found to prevent bacterial infiltration into the wound site due to forming an impermeable barrier between the wound bed and external environment. The optimized hydrogel was found to significantly hasten skin regeneration in animal models when compared to other treatments in addition to strong inhibitory effect on the release of pro-inflammatory cytokines (interleukin-1β and tumor necrosis factor-α). Conclusions: Our results suggest that sodium alginate -based hydrogels loaded with Chol-37(F34-R) hold the potential to be used as an alternative to conventional antibiotics in treating infectious skin wounds.