• Title/Summary/Keyword: Canonical Structure

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Echolocation Call Structure of Fourteen Bat Species in Korea

  • Fukui, Dai;Hill, David A.;Kim, Sun-Sook;Han, Sang-Hoon
    • Animal Systematics, Evolution and Diversity
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    • v.31 no.3
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    • pp.160-175
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    • 2015
  • The echolocation calls of bats can provide useful information about species that are generally difficult to observe in the field. In many cases characteristics of call structure can be used to identify species and also to obtain information about aspects of the bat's ecology. We describe and compare the echolocation call structure of 14 of the 21 bat species found in Korea, for most of which the ecology and behavior are poorly understood. In total, 1,129 pulses were analyzed from 93 echolocation call sequences of 14 species. Analyzed pulses could be classified into three types according to the pulse shape: FM/CF/FM type, FM type and FM/QCF type. Pulse structures of all species were consistent with previous studies, although geographic variation may be indicated in some species. Overall classification rate provided by the canonical discriminant analysis was relatively low. Especially in the genera Myotis and Murina, there are large overlaps in spectral and temporal parameters between species. On the other hand, classification rates for the FM/QCF type species were relatively high. The results show that acoustic monitoring could be a powerful tool for assessing bat activity and distribution in Korea, at least for FM/QCF and FM/CF/FM species.

How Z-DNA/RNA binding proteins shape homeostasis, inflammation, and immunity

  • Kim, Chun
    • BMB Reports
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    • v.53 no.9
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    • pp.453-457
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    • 2020
  • The right-handed double-helical structure of DNA (B-DNA), which follows the Watson-Crick model, is the canonical form of DNA existing in normal physiological settings. Even though an alternative left-handed structure of DNA (Z-DNA) was discovered in the late 1970s, Z-form nucleic acid has not received much attention from biologists, because it is extremely unstable under physiological conditions, has an ill-defined mechanism of its formation, and has obscure biological functions. The debate about the physiological relevance of Z-DNA was settled only after a class of proteins was found to potentially recognize the Z-form architecture of DNA. Interestingly, these Z-DNA binding proteins can bind not only the left-handed form of DNA but also the equivalent structure of RNA (Z-RNA). The Z-DNA/RNA binding proteins present from viruses to humans function as important regulators of biological processes. In particular, the proteins ADAR1 and ZBP1 are currently being extensively re-evaluated in the field to understand potential roles of the noncanonical Z-conformation of nucleic acids in host immune responses and human disease. Despite a growing body of evidence supporting the biological importance of Z-DNA/RNA, there remain many unanswered principal questions, such as when Z-form nucleic acids arise and how they signal to downstream pathways. Understanding Z-DNA/RNA and the sensors in different pathophysiological conditions will widen our view on the regulation of immune responses and open a new door of opportunity to develop novel types of immunomodulatory therapeutic possibilities.

Variable Structure Control Design Based on Eigenvalues Assignment of Sliding Mode (슬라이딩 모드 고유치 설정에 기반을 둔 가변구조 제어 설계)

  • Hong, Yeon-Chan;Lee, Tae-Bong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.6
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    • pp.2207-2213
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    • 2010
  • A new scheme for variable structure control design which is based on eigenvalues assignment of sliding mode is developed. In conventional methods, generally, specific type of system matrix like canonical or regular form is required to construct a switching surface. Furthermore, the methods are not explicit. The new method in this paper solved the problems. No special type of system matrix is required and very explicit. It is shown that the switching surface can be constructed and determined uniquely without any dependency on the system form. The proposed method is based on the fact that the dynamics of sliding mode is determined by system zeros. Finally, a numerical example is given to verify the validity of the results studied in this paper.

Numerical Experiments of Ocean Acoustic Tomography in the East Sea of Korea

  • Han, Sang-Kyu;Na, Jung-Yul;Lee, Jae-Hak
    • Journal of the korean society of oceanography
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    • v.31 no.2
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    • pp.64-74
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    • 1996
  • Numerical experiments of OAT (Ocean Acoustic Tomography) are carried out in the East Sea of Korea where the canonical ocean has been perturbed by a mesoscale warm eddy and a thermal front. In order to estimate the horizontal and vertical structure of water temperature of the perturbed ocean, the experimental area is divided into 16 cells with 8 pairs of sources and receivers for a horizontal slice and the water column is divided into 8 layers for a vertical slice. The inversely estimated temperature field by using SVD (Singular Value Decomposition) method reveals the eddy and frontal structure clearly. The rms errors of the two horizontal slices are less than $0.4^{\circ}C$ and $1.7^{\circ}C$ at 400 m and 200 m depths, respectively, while the error in the vertical slice is less than $1.0^{\circ}C.$ For better estimation of temperature by OAT method, particularly for the East Sea, a range-dependent ray model should be used to solve the forward problem. At the same time, improvement in computing the refracted ray path between vertical layers is required to obtain more accurate travel time information. The results of the present experiment give rise to a possibility of application of OAT in remote sensing of the ocean thermal structure.

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CONTACT THREE CR-SUBMANIFOLDS OF A (4m + 3)-DIMENSIONAL UNIT SPHERE

  • Kim, Hyang-Sook;Kim, Young-Mi;Kwon, Jung-Hwan;Pak, Jin-Suk
    • Journal of the Korean Mathematical Society
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    • v.44 no.2
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    • pp.373-391
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    • 2007
  • We study an (n+3)($n\;{\geq}\;7-dimensional$ real submanifold of a (4m+3)-unit sphere $S^{4m+3}$ with Sasakian 3-structure induced from the canonical quaternionic $K\"{a}hler$ structure of quaternionic (m+1)-number space $Q^{m+1}$, and especially determine contact three CR-submanifolds with (p-1) contact three CR-dimension under the equality conditions given in (4.1), where p = 4m - n denotes the codimension of the submanifold. Also we provide necessary conditions concerning sectional curvature in order that a compact contact three CR-submanifold of (p-1) contact three CR-dimension in $S^{4m+3}$ is the model space $S^{4n_1+3}(r_1){\times}S^{4n_2+3}(r_2)$ for some portion $(n_1,\;n_2)$ of (n-3)/4 and some $r_1,\;r_2$ with $r^{2}_{1}+r^{2}_{2}=1$.

Performance Evaluation of Military Corps with Categorical Environmental Variables (범주형 환경변수를 고려한 부대성과평가 방법에 관한 연구 - DEA와 CCCA의 결합을 중심으로 -)

  • Lee, Kyung-Won;Park, Myung-Seop;Im, Jae-Poong
    • Journal of the military operations research society of Korea
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    • v.32 no.1
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    • pp.51-72
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    • 2006
  • There are many occasions that the performance of a corps is influenced not only by its own efforts but by the commander of the next higher unit in a vertical organizational structure. When the direction of the commander in the next higher organization is different from that of the actual evaluation agency, the unit under evaluation may get rated lower than what it should deserve. This study suggests an alternative method to evaluate the performance of military units in the situation that there exist critical environmental factors which affect the performance. This method employes DEA, a non parametric method, and Constrained Canonical Correlation Analysis(CCCA), a parametric method which is used to estimate a efficient frontier with multiple dependent variables and constraints. This article also exploits a set of categorical environmental variables in the CCCA to improve the fairness of performance evaluation. It is shown that the introduction of the categorical variables helps evaluating the true performance of individual units such as battalions subordinated to different next higher commanders.

The Influence of Nutrients Concentration and the Ratio on Phytoplankton Community Structure during Late Spring and Early Summer in Sagami Bay, Japan (춘계와 하계의 영양염 농도와 그 구성비가 식물플랑크톤의 군집구조에 미치는 영향평가)

  • Baek, Seung-Ho;Shimode, Shinji;Han, Myung-Soo;Kikuchi, Tomohiko
    • ALGAE
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    • v.23 no.4
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    • pp.277-288
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    • 2008
  • The relationship between nutrients and phytoplankton dynamics was investigated daily from 12 April to 22 July 2003 in Sagami Bay, Japan. According to multidimensional scaling (MDS) and cluster analysis, phytoplankton community was divided into four distinct groups. The first group was consisted of centric diatom species, such as Guinardia spp., Detonula spp., Letocylindrus danicus, Skeletonema costatum, Eucampia zodiacus and Chaetoceros spp.. The second and third clusters comprised mainly diatoms and dinoflagellates, respectively. The other cluster was restricted to the samples collected during the last sampling period when the rainfall and river discharge was frequently recorded. Canonical correspondence analysis (CCA) was applied to analyze four groups respectively, which focused on the effects of nutrients concentration and ratio on phytoplankton variations. Based on CCA analysis, most species of centric diatom were negatively correlated with DSi concentrations and Si/N ratio. Nutrients were strongly limited phytoplankton growth during the summer when the rainfall was not observed, whereas river discharge by rainfall and counterclockwise coastal currents (although the surface circulation pattern is often altered by Kuroshio Current, the counterclockwise coastal currents are generally dominant) has brought phytoplankton population accumulation and triggered the micoalgae growth in western part of the bay. Phosphorous (P) was strongly limited after significantly increases in the phytoplankton abundances. However, silicate (Si) was not a major limiting factor for phytoplankton production, since Si/DIN and Si/P ratio did not create any potential stoichiometric limitation. This indicates that high Si availability contributes favorably to the maintenance of diatom ecosystems in Sagami Bay.

IL-34 Aggravates Steroid-Induced Osteonecrosis of the Femoral Head via Promoting Osteoclast Differentiation

  • Feng Wang;Hong Sung Min;Haojie Shan;Fuli Yin;Chaolai Jiang;Yang Zong;Xin Ma;Yiwei Lin;Zubin Zhou;Xiaowei Yu
    • IMMUNE NETWORK
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    • v.22 no.3
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    • pp.25.1-25.11
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    • 2022
  • IL-34 can promote osteoclast differentiation and activation, which may contribute to steroid-induced osteonecrosis of the femoral head (ONFH). Animal model was constructed in both BALB/c and IL-34 deficient mice to detect the relative expression of inflammation cytokines. Micro-CT was utilized to reveal the internal structure. In vitro differentiated osteoclast was induced by culturing bone marrow-derived macrophages with IL-34 conditioned medium or M-CSF. The relative expression of pro-inflammation cytokines, osteoclast marker genes, and relevant pathways molecules was detected with quantitative real-time RT-PCR, ELISA, and Western blot. Up-regulated IL-34 expression could be detected in the serum of ONFH patients and femoral heads of ONFH mice. IL-34 deficient mice showed the resistance to ONFH induction with the up-regulated trabecular number, trabecular thickness, bone value fraction, and down-regulated trabecular separation. On the other hand, inflammatory cytokines, such as TNF-α, IFN-γ, IL-6, IL-12, IL-2, and IL-17A, showed diminished expression in IL-34 deficient ONFH induced mice. IL-34 alone or works in coordination with M-CSF to promote osteoclastogenesis and activate ERK, STAT3, and non-canonical NF-κB pathways. These data demonstrate that IL-34 can promote the differentiation of osteoclast through ERK, STAT3, and non-canonical NF-κB pathways to aggravate steroid-induced ONFH, and IL-34 can be considered as a treatment target.

Characteristics of Fish Fauna and Community Structure in Ungcheon Stream due to the Environmental Changes (환경변화에 따른 웅천천의 어류상과 어류 군집 특성)

  • Jung, Hwa-Young;Kim, Kyeong-Hwan;Song, Mi-Young;Lee, Wan-Ok
    • Korean Journal of Environment and Ecology
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    • v.28 no.3
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    • pp.314-325
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    • 2014
  • We studied fish fauna at 10 study sites in Ungcheon stream for 4 times from April to October, 2011 to investigate the influence of artificial structures such as dam (with fish-way) and weir (without fish-way), and abandoned mine on fish community. A total of 12 families, 36 species of fishes were collected. Dominant species was Zacco platypus (23.4%) and subdominant species was Zacco koreanus (20.5%). Ten species (27.8%) of Korean endemic species and Micropterus salmoides, exotic species, were observed during the study period. Endangered species of Korea such as Pseudopungtungia nigra and Liobagrus obesus, and Korean endemic species, Coreoperca herzi, which are vulnurable for water quality and had been observed in previous study, were not identified in this study. According to the cluster analysis, Ungcheon stream were divided into three groups consisting upstream (St.1, St.2, St.3), midstream (St.4, St.5, St.6, St.7), downstream (St.8, St.9, St.10). Community structure similarity between upper and lower site of Boryeong dam with fish-way (St.6-St.7) was high, whereas that of weir, lack of fish-way (St.7-St.8) showed little similarity indicating that fish-way was required. According to the canonical correlation analysis, high level of conductivity and salinity at upstream was detected and Misgurnus mizolepis, and endemic species of Korea such as Silurus microdorsalis, Coreoleuciscus splendidus and Iksookimia koreensis were observed at this part of the stream. Since Korean endemic species, Squalidus gracilis majimae cohabit with exotic species, M. Salmoides at downstream whose width is wide and water velocity is low, protection was needed for these endemic species.

NONEXISTENCE OF A CREPANT RESOLUTION OF SOME MODULI SPACES OF SHEAVES ON A K3 SURFACE

  • Choy, Jae-Yoo;Kiem, Young-Hoon
    • Journal of the Korean Mathematical Society
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    • v.44 no.1
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    • pp.35-54
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    • 2007
  • Let $M_c$ = M(2, 0, c) be the moduli space of O(l)-semistable rank 2 torsion-free sheaves with Chern classes $c_1=0\;and\;c_2=c$ on a K3 surface X, where O(1) is a generic ample line bundle on X. When $c=2n\geq4$ is even, $M_c$ is a singular projective variety equipped with a holomorphic symplectic structure on the smooth locus. In particular, $M_c$ has trivial canonical divisor. In [22], O'Grady asks if there is any symplectic desingularization of $M_{2n}$ for $n\geq3$. In this paper, we show that there is no crepant resolution of $M_{2n}$ for $n\geq3$. This obviously implies that there is no symplectic desingularization.