• Title/Summary/Keyword: Candidate Selection

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A Study on the selection of the optimum route using geographic information system (G.I.S 기법을 활용한 최적노선에 관한 연구)

  • 최재화;서용운;이석배
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.9 no.2
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    • pp.127-138
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    • 1991
  • This is a study on the selection of the optimum route using geographic information system. In general, the selection of route was classifed in order of candidate route zone, optimum route zone and optimum route, this study comes under optimum route that is the last part in the route planning. The optimum route is get attined on the weighted matrix table that based on landuse status, land value, slope degree of each grid cell of the test area, and also we suggest application possibility of geographic information system in the route planning with the comparision and analysis of the three selection route in this study.

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Joint Mode Selection, Link Allocation and Power Control in Underlaying D2D Communication

  • Zhang, Wei;He, Wanbing;Wu, Dan;Cai, Yueming
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.11
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    • pp.5209-5228
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    • 2016
  • Device-to-device (D2D) communication underlaying cellular networks can bring significate benefits for improving the performance of mobile services. However, it hinges on elaborate resource sharing scheme to coordinate interference between cellular users and D2D pairs. We formulate a joint mode selection, link allocation and power control optimization problem for D2D communication sharing uplink resources in a multi-user cellular network and consider the efficiency and the fairness simultaneously. Due to the non-convex difficulty, we propose a three-step scheme: firstly, we conduct mode selection for D2D pairs based on a minimum distance metric after an admission control and obtain some cellular candidates for them. And then, a cellular candidate will be paired to each D2D pair based on fairness. Finally, we use Lagrangian Algorithm to formulate a joint power control strategy for D2D pairs and their reused cellular users and a closed-form of solution is derived. Simulation results demonstrate that our proposed algorithms converge in a short time. Moreover, both the sum rate of D2D pairs and the energy efficiency of cellular users are improved.

Selection signature reveals genes associated with susceptibility loci affecting respiratory disease due to pleiotropic and hitchhiking effect in Chinese indigenous pigs

  • Xu, Zhong;Sun, Hao;Zhang, Zhe;Zhang, Cheng-Yue;Zhao, Qing-bo;Xiao, Qian;Olasege, Babatunde Shittu;Ma, Pei-Pei;Zhang, Xiang-Zhe;Wang, Qi-Shan;Pan, Yu-Chun
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.2
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    • pp.187-196
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    • 2020
  • Objective: Porcine respiratory disease is one of the most important health problems causing significant economic losses. To understand the genetic basis for susceptibility to swine enzootic pneumonia (EP) in pigs, we detected 102,809 single nucleotide polymorphisms in a total of 249 individuals based on genome-wide sequencing data. Methods: Genome comparison of susceptibility to swine EP in three pig breeds (Jinhua, Erhualian, and Meishan) with two western lines that are considered more resistant (Duroc and Landrace) using cross-population extended haplotype homozygosity and F-statistic (FST) statistical approaches identified 691 positively selected genes. Based on quantitative trait loci, gene ontology terms and literature search, we selected 14 candidate genes that have convincible biological functions associated with swine EP or human asthma. Results: Most of these genes were tested by several methods including transcription analysis and candidate genes association study. Among these genes: cytochrome P450 1A1 and catenin beta 1 (CTNNB1) are involved in fertility; transforming growth factor beta receptor 3 plays a role in meat quality traits; Wnt family member 2, CTNNB1 and transcription factor 7 take part in adipogenesis and fat deposition simultaneously; plasminogen activator, urokinase receptor (completely linked to AXL receptor tyrosine kinase, r2 = 1) plays an essential role in the successful ovulation of matured oocytes in pigs; colipase like 2 (strongly linked to SAM pointed domain containing ETS transcription factor, r2 = 0.848) is involved in male fertility. Conclusion: These adverse genes susceptible to swine EP may be selected while selecting for economic traits (especially reproduction traits) due to pleiotropic and hitchhiking effect of linked genes. Our study provided a completely new point of view to understand the genetic basis for susceptibility or resistance to swine EP in pigs thereby, provides insight for designing sustainable breed selection programs. Finally, the candidate genes are crucial due to their potential roles in respiratory diseases in a large number of species, including human.

Reviewing the Candidate Types for Other Effective Area-based Conservation Measures for Post-2020 Management Related to National Protected Areas System (Post-2020 국가 보호지역 시스템 관리를 위한 기타 효과적인 지역 기반 보전 수단(OECMs) 후보지역 유형 검토)

  • Shim, Yun-Jin;Sung, Jung-Won;Lee, Kyeong-Cheol;Kweon, Hyeong-Keun;Hong, Yong-Sik;Kang, Shin-Gu;An, Jong-Bin
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.25 no.1
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    • pp.11-23
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    • 2022
  • This study aims to systematically review the candidate types for OECMs suitable for domestic conditions in areas related to the Korea Forest Service in order to achieve the goal of establishing the protected areas and OECMs system required by Post-2020 GBF, and to provide basic data for the establishment of the national protected areas system. As a result of the study, the selection criteria for OECMs were presented, and it was found that arboretums·botanical gardens, Natural Recreation Forests, and air holes may correspond to the Candidate Types for OECMs. As a result of evaluating the possible areas for OECMs based on the OECMs selection criteria, in the case of arboretums·botanical gardens, it is judged that only conservation areas can be designated as OECMs, except for areas mainly used by visitors of arboretums·botanical gardens that fall under the BGCI conservation type among national and public arboretums·botanical gardens. However, private and school arboretums·botanical gardens have personal property ownership, so it was judged to have no effective measures to control activities that may adversely affect biodiversity, which showed limitations in designation of OECMs. Natural Recreation Forests was found to meet the OECMs selection criteria. However, private forests have personal property ownership, which limits the designation of OECMs. Therefore, it is necessary to strengthen the function of in-situ conservation in order to meet the OECMs for private and school arboretums·botanical gardens, and private forests that have personal property ownership. To this end, effective measures are needed to achieve biodiversity conservation outcomes, and it is judged that legal control and corresponding support policies (incentives) are needed. In the case of air holes, for sustainable conservation, the management boundary of air holes should be clearly defined based on the preparation of laws and guidelines related to air holes. In addition, it is judged that it is desirable to designate the competent local forest office as the management authority and conduct periodic detailed surveys of air holes, establish and implement the conservation plans based on those.

Identification of genomic diversity and selection signatures in Luxi cattle using whole-genome sequencing data

  • Mingyue Hu;Lulu Shi;Wenfeng Yi;Feng Li;Shouqing Yan
    • Animal Bioscience
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    • v.37 no.3
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    • pp.461-470
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    • 2024
  • Objective: The objective of this study was to investigate the genetic diversity, population structure and whole-genome selection signatures of Luxi cattle to reveal its genomic characteristics in terms of meat and carcass traits, skeletal muscle development, body size, and other traits. Methods: To further analyze the genomic characteristics of Luxi cattle, this study sequenced the whole-genome of 16 individuals from the core conservation farm in Shandong region, and collected 174 published genomes of cattle for conjoint analysis. Furthermore, three different statistics (pi, Fst, and XP-EHH) were used to detect potential positive selection signatures related to selection in Luxi cattle. Moreover, gene ontology and Kyoto encyclopedia of genes and genomes pathway enrichment analyses were performed to reveal the potential biological function of candidate genes harbored in selected regions. Results: The results showed that Luxi cattle had high genomic diversity and low inbreeding levels. Using three complementary methods (pi, Fst, and XP-EHH) to detect the signatures of selection in the Luxi cattle genome, there were 2,941, 2,221 and 1,304 potentially selected genes identified, respectively. Furthermore, there were 45 genes annotated in common overlapping genomic regions covered 0.723 Mb, including PLAG1 zinc finger (PLAG1), dedicator of cytokinesis 3 (DOCK3), ephrin A2 (EFNA2), DAZ associated protein 1 (DAZAP1), Ral GTPase activating protein catalytic subunit alpha 1 (RALGAPA1), mediator complex subunit 13 (MED13), and decaprenyl diphosphate synthase subunit 2 (PDSS2), most of which were enriched in pathways related to muscle growth and differentiation and immunity. Conclusion: In this study, we provided a series of genes associated with important economic traits were found in positive selection regions, and a scientific basis for the scientific conservation and genetic improvement of Luxi cattle.

Association of Candidate Genes with Production Traits in Korean Dairy Proven and Young Bulls

  • Jang, G.W.;Cho, K.H.;Kim, T.H.;Oh, S.J.;Cheong, I.C.;Lee, K.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.2
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    • pp.165-169
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    • 2005
  • This study was performed to offer effective basic data for selection and improvement of Korean dairy cattle through identifying distributional properties among candidate genes (bovine butyrophilin, signal transducers and activators of transcription 5a, and prolactin hormone). In this study, polymorphisms of candidate genes were identified and the relationships between loci and production traits of each gene were analyzed using frozen semen of Holstein bulls (19 proven and 77 candidates). In butyrophilin (BTN) locus, polymorphisms information contents (PIC) value of BTN2 (0.372) was higher than those of others (BTN1; 0.155, BTN3; 0.254, BTN4; 0.169). As a result of analysis of genotyping STAT5a, using single stranded conformational polymorphism (SSCP) method and microsatellite locus, PIC values were 0.189 and 0.457, respectively. And PIC value of prolactin hormone gene was 0.176. In the relationships between genotypes and production traits, BTN3 was associated with 305-day production traits (p<0.05). PTAs for B allele were such as 110.43, 88.28 and 75.25 in BTN1, 3, 4 and these values were higher than those of A allele, but in the case of BTN2, A allele with 154.19 was higher than that of B allele. The results obtained from using candidate genes may be used as an useful index for the genetic improvement of dairy cattle population in Korea, and further studies are needed.

Methodology for Prioritizing Sidewalk Construction among 100 Candidate Sites on Rural National Highways (지방부 국도에서의 보도설치 우선순위 결정을 위한 방법론 개발 (일반국도 적용사례 중심으로))

  • Jeon, Woo Hoon;Yang, Choong Heon;Yoon, Jung Eun;Yang, Inchul
    • International Journal of Highway Engineering
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    • v.17 no.4
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    • pp.127-133
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    • 2015
  • PURPOSES: The purpose of this study is to develop a methodology to prioritize sidewalk construction on rural national highways. METHODS : In order to determine an appropriate prioritization for sidewalk construction, we developed a specific methodology. The proposed methodology includes three main steps: 1) Analytic Hierarchy Process (AHP) methods, 2) Subjective evaluation of relevant road agencies for the candidate sidewalks along rural national highways, and 3) Field study conduction. Each step has four phases. The primary feature of this methodology is the addition of expert consultation and survey data, as well as a field study. In addition, the method could guarantee flexibility in selection for evaluation criteria. As a result, the proposed methodology could be used as a general procedure for application to other roadway classifications when considering sidewalk construction. RESULTS: In order to demonstrate the reasonableness of the proposed methodology, a case study was performed for exactly 100 candidate sites for sidewalk construction on rural national highways. All required evaluation scores were properly produced for each candidate site. By doing so, decision-makers can determine the priority for sidewalk construction at these sites by reviewing quantitatively and qualitatively considered data. CONCLUSIONS: The results of the case study can be applied to a long-term fundamental plan for sidewalk construction on rural national highways. Furthermore, this methodology could be employed to prioritize a small-scale SOC project(e. g. bicycle or pedestrian roads).

Current Research Status for Economically Important Candidate Genes and Microarray Studies in Cattle (소의 경제형질 관련 후보 유전자 및 Microarray 연구현황)

  • 유성란;이준헌
    • Journal of Animal Science and Technology
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    • v.48 no.2
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    • pp.169-190
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    • 2006
  • Researches in livestock are currently actively progressing to improve economically important traits using DNA markers. In cattle, the candidate genes have been selected based on their known functions in the target QTL (quantitative trait locus) region in order to identify QTN (quantitative trait nucleotide) for improving productivities. In this review, molecular genetic studies for the meat related traits, one of the major determinant of market prices, have been fully described. Also recent emerging microarray technique for identifying candidate genes in cattle has been discussed. In case of microarray, cDNA microarrays have been replaced to oligoarrays in order to minimize the experimental errors in cattle. Since the first draft of bovine genome sequences was appeared in the public domain, more markers in relation to the quantitative traits will be discovered in a short period of time and genes affecting difficult-to-measure traits, such as disease resistance, can also be selected for marker assisted selection in near future.

Deep Learning-based Approach for Classification of Tribological Time Series Data for Hand Creams (딥러닝을 이용한 핸드크림의 마찰 시계열 데이터 분류)

  • Kim, Ji Won;Lee, You Min;Han, Shawn;Kim, Kyeongtaek
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.44 no.3
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    • pp.98-105
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    • 2021
  • The sensory stimulation of a cosmetic product has been deemed to be an ancillary aspect until a decade ago. That point of view has drastically changed on different levels in just a decade. Nowadays cosmetic formulators should unavoidably meet the needs of consumers who want sensory satisfaction, although they do not have much time for new product development. The selection of new products from candidate products largely depend on the panel of human sensory experts. As new product development cycle time decreases, the formulators wanted to find systematic tools that are required to filter candidate products into a short list. Traditional statistical analysis on most physical property tests for the products including tribology tests and rheology tests, do not give any sound foundation for filtering candidate products. In this paper, we suggest a deep learning-based analysis method to identify hand cream products by raw electric signals from tribological sliding test. We compare the result of the deep learning-based method using raw data as input with the results of several machine learning-based analysis methods using manually extracted features as input. Among them, ResNet that is a deep learning model proved to be the best method to identify hand cream used in the test. According to our search in the scientific reported papers, this is the first attempt for predicting test cosmetic product with only raw time-series friction data without any manual feature extraction. Automatic product identification capability without manually extracted features can be used to narrow down the list of the newly developed candidate products.

Genome-wide association study identifies positional candidate genes affecting back fat thickness trait in pigs

  • Lee, Jae-Bong;Kang, Ho-Chan;Kim, Eun-Ho;Kim, Yoon-Joo;Yoo, Chae-Kyoung;Choi, Tae-Jeong;Lim, Hyun-Tae
    • Korean Journal of Agricultural Science
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    • v.45 no.4
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    • pp.707-713
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    • 2018
  • This study was done to search for positional candidate genes associated with the back fat thickness trait using a Genome-Wide Association Study (GWAS) in purebred Yorkshires (N = 1755). Genotype and phenotype analyses were done for 1,642 samples. As a result of the associations with back fat thickness using the Gemma program (ver. 0.93), when the genome-wide suggestive threshold was determined using the Bonferroni method ($p=1.61{\times}10^{-5}$), the single nucleotide polymorphism (SNP) markers with suggestive significance were identified in 1 SNP marker on chromosome 2 (MARC0053928; $p=3.65{\times}10^{-6}$), 2 SNP markers on chromosome 14 (ALGA0083078; $p=7.85{\times}10^{-6}$, INRA0048453; $p=1.27{\times}10^{-5}$), and 1 SNP marker on chromosome 18 (ALGA0120564; $p=1.44{\times}10^{-5}$). We could select positional candidate genes (KCNQ1, DOCK1, LOC106506151, and LOC110257583), located close to the SNP markers. Among these, we identified a potassium voltage-gated channel subfamily Q member gene (KCNQ1) and the dedicator of cytokinesis 1 (DOCK1) gene associated with obesity and Type-2 diabetes. The SNPs and haplotypes of the KCNQ1 and DOCK1 genes can contribute to understanding the genetic structure of back fat thickness. Additionally, it may provide basic data regarding marker assisted selection for a meat quality trait in pigs.