• 제목/요약/키워드: Candida albacans

검색결과 1건 처리시간 0.016초

(1,3)$\beta$-Glucansynthase효소 억제 활성을 가진 천연물의 검색 (Screening of Antifungal Natural Products with Inhibitory Effects on (1,3)$\beta$-glucan Synthase)

  • 천현자;김영순;이영행;곽규범;권석용;권태오;채규윤
    • 동의생리병리학회지
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    • 제17권6호
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    • pp.1509-1513
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    • 2003
  • Antifungal activities of the extracts from 26 medicinal plants were investigated utilizing paper-disk diffusion method and (1,3)β-glucan synthase inhibitory assay. (1,3)β-glucan synthase is considered as valuable target in the development of antifungal agents. Among the screened extracts, the ethyl acetate extract of Equisetum arvense, the ethyl acetate extract of Polygonum aviculare, the butanol extract of Crataegus pinnatifida and the n-hexane extract of Saussurea lappa showed significant antifungal activities on Candida albacans in both disk diffusion and enzyme assays.