• Title/Summary/Keyword: Candida albacans

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Screening of Antifungal Natural Products with Inhibitory Effects on (1,3)$\beta$-glucan Synthase ((1,3)$\beta$-Glucansynthase효소 억제 활성을 가진 천연물의 검색)

  • Chun Hyun Ja;Kim Young Sun;Lee Young Hang;Kwak Geu Byum;kwon Suk young;Kwon Tae Oh;Chai Geu Yun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.6
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    • pp.1509-1513
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    • 2003
  • Antifungal activities of the extracts from 26 medicinal plants were investigated utilizing paper-disk diffusion method and (1,3)β-glucan synthase inhibitory assay. (1,3)β-glucan synthase is considered as valuable target in the development of antifungal agents. Among the screened extracts, the ethyl acetate extract of Equisetum arvense, the ethyl acetate extract of Polygonum aviculare, the butanol extract of Crataegus pinnatifida and the n-hexane extract of Saussurea lappa showed significant antifungal activities on Candida albacans in both disk diffusion and enzyme assays.