• Journal of Hospice and Palliative Care
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• 제10권4호
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• pp.184-189
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• 2007

목적: 효과적인 통증관리의 장애요인은 크게 제도적 측면, 의료진 측면, 그리고 환자 측면으로 구분되며, 이는 모두 사회적 통념에 영향을 받는다. 따라서 본 연구는 일반인의 통증관리 장애요인을 규명하여 궁극적으로 우리 사회의 통증관리에 대한 이해를 향상시키기 위한 기초 자료를 마련하고자 시도되었다. 방법: 2007년 5월 15일부터 6월 15일까지 자원봉사자, 교사 및 지역사회 주민 163명을 대상으로 Gunnarsdottir, Donovan, Serlin, Voge와 Ward (2002)가 개발한 Barriers Questionnaire II (BQ-II)를 유양숙, 이원희, 조옥희와 이소우(2005)가 번한 보완한 통증관리 장애척도를 사용하여 자료를 수집하였다. 통증관리 장애척도의 Cronbach's $\alpha$는 .88이었다. 결과: 대상자의 평균연령은 53.36세이며, 92.6%가 통증교육을 받은 경험이 없었다. 대상자의 통증장애 정도는 평균 2.51점이었으며, 중독을 포함하는 해로운 영향 영역이 3.03점, 부작용을 포함하는 신체적 효과 영역 2.73점, 숙명론적 태도 영역 2.15점, 그리고 의사소통 영역 1.71점 순이었다. 문항별로는 '진통제를 사용하면 중독의 위험이 있다'의 장애정도가 가장 높았고, 다음은 '진통제를 사용하면 새로운 통증이 생겼을 때 알기가 어렵다', '진통제를 사용하면 몸이 익숙해져 곧 진통효과가 없을 것이다', '진통제로 인한 졸림은 조절하기 어렵다', '진통제는 면역력을 떨어뜨린다' 순이었다. 통증교육을 받은 경우의 통증관리 장애정도는 교육을 받지 않은 경우보다 유의하게 낮았다. 결론: 일반인들의 통증관리 장애요인은 환자나 가족과 유사하게 진통제 중독 및 내성에 대한 염려가 가장 높았으므로 사회적으로 확산되어 있는 통증관리 및 진통제 사용에 대한 올바른 이해를 높이기 위한 교육 및 홍보가 필요하다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권9호
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• pp.4335-4340
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• 2016

Background: Bone metastasis is a single condition but presents with various patterns and severities. Skeletal-related events (SREs) deteriorate overall performance status and reduce quality of life. However, guidelines for early detection and management are limited. This study includes a survey of the prevalence of bone metastasis in cases with common cancers in Thailand as well as a focus on survival patterns and SREs. Materials and Methods: A retrospective cohort analysis was conducted using a database of the Chiang Mai Cancer Registry and the Musculoskeletal Tumor Registry of the OLARN Center, Chiang Mai University. The prevalence of bone metastasis from each type of primary cancer was noted and time-to-event analysis was performed to estimate cancer survival rates after bone metastasis. Results: There were 29,447 cases of the ten most common cancers in Thailand, accounting for 82.2% of the entire cancer registry entries during the study period. Among those cases, there were 2,263 with bone metastases, accounting for 7.68% of entries. Bone metastasis from lung, liver, breast, cervix and prostate are common in the Thai population, accounting for 83.4% of all positive cases. The median survival time of all was 6 months. Of the bone metastases, 48.9% required therapeutic intervention, including treatment of spinal cord and nerve root compression, pathological fractures, and bone pain. Conclusions: The frequency of the top five types of bone metastasis in Thailand were different from the frequencies in other countries, but corresponded to the relative prevalence of the cancers in Thailand and osteophilic properties of each cancer. The results of this study support the establishment of country specific guidelines for primary cancer identification with skeletal lesions of unknown origin. In addition, further clinical studies of the top five bone metastases should be performed to develop guidelines for optimal patient management during palliative care.

• Journal of Gastric Cancer
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• 제1권4호
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• pp.215-220
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• 2001

Purpose: The aim of the study was to obtain data on the anatomic and histologic distributions, the clinical features, and the treatment results for patients with primary gastric non-Hodgkin's lymphoma. Materials and Methods: One hundred thirty-two patients who were treated at 8 university hospitals and 2 general hospitals between January 1991 and December 2000 were enrolled to evaluate clinico-pathologic features. Results: The lower one-third of the stomach was the most frequent site ($42\%$), and the most frequent chief complaint was epigastric pain ($54\%$). Gastric resection was performed in 114 cases. Pathologic findings of preoperative endoscopic biopsy specimens from the 114 patients that underwent surgery were a gastric lymphoma in 94 cases ($82\%$), a carcinoma in 15 cases ($13\%$), an ulcer in 4 cases ($4\%$), and a gastrointestinal stromal tumor in 1 case ($1\%$). The stage distributions by Musshoff's criteria were 71 cases ($54\%$) of stage IE, 36 cases ($27\%$) of stage $II_{1}E$, 8 cases ($6\%$) of stage $II_{2}E$, 2 cases ($2\%$) of stage IIIE, and 15 cases ($11\%$) of stage IVE. Histologic gradings by the Working Formulation in were 31 cases ($23\%$) of low grade, 96 cases ($73\%$) of intermediate grade, and 5 cases ($4\%$) of high grade. Chemotherapy-related complications occurred in 25 cases ($22\%$) while operation-related complications occurred in 6 cases ($5\%$). Seventeen patients ($13\%$) only underwent surgery, 19 ($14\%$) had chemotherapy (CTx) and/or radiotherapy (RTx) only, and 96 patients ($73\%$) received surgery and CTx and/or RTx. No substantial differences in survival were found in relation to the different histologic grades and different treatments. The five-year survival was $85\%$ in stage I or II and $47\%$ in stage III or IV (P=0.0000). Conclusion: Pathologic stage appears to be the single most important prognostic indicator. Survival differences according to treatment modalities were not statistically significant. However, the low number of patients treated with various approaches over a long period precludes a firm conclusion.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1539-1541
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• 2012

Cholangitis is relatively uncommon but associated mortality is high due to the predisposition in people with underlying disease. For this recognition of contributing risk factors is necessary. Therefore, the present descriptive-analytical cross-sectional survey was designed to determine contributing risk factors for post-ERCP cholangitis in patients with pancreatic cancer. From 2005 to 2010, 110 consecutive cases of pancreatic cancer attending to a tertiary referral centre (Taleghani Hospital), Tehran, Iran were recruited. The patients all underwent stenting via endoscopic retrograde cholangiopancreatography (ERCP). On univariate analysis, a metallic stent type (95% confidence interval (CI) 1.025-11.34, P=0.037), having no jaundice (1.44-2.22, P=0.009), having no pain (1.32-1.91, P=0.026), a history of prior ERCP (1.16-10.37, P=0.020), and having a proximal biliary stone (1.002-5.93, P=0.046) were related to cholangitis. However on multivariate analysis, none of these factors were found to be contributing risk factors. Cholangitis is avoidable with adequate biliary drainage. Because success rates are higher and complication rates lower for endoscopists performing large volumes of ERCP, performance of the procedure should be concentrated as much as possible in institutions with endoscopists having adequate experience. Patients with a high risk for complications may be best served by referral to an advanced center.

• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.165-170
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• 2016

Background: Nurses are the most visible, frontline personnel providing health education to patients. In particular, nurse experience with Pap examinations have the potential to influence women's attitudes toward screening for cervical cancer. However, nurses in Taiwan have lower rates of Pap testing than the general population. Understanding the factors predicting nurse intent to have a Pap exam and Pap exam status would inform interventions and policies to increase their Pap exam uptake. Therefore, the present study was undertaken. Materials and Methods: Data were collected by questionnaire from a convenient sample of 504 nurses at a regional hospital in central Taiwan between August and October 2011 and analyzed by descriptive statistics, confirmatory factor analysis, and logistic regression. Results: Nurse intention to have a Pap exam was predicted by younger age, less negative attitudes toward Pap exams, and greater influence of others recommendations. However, nurses were more likely to actually have had a Pap exam if they were older, married, had sexual experience, and had a high intention to have a Pap exam. Conclusions: Nurses who are younger than 34 years old, unmarried, sexually inexperienced, and with low intention to have a Pap exam should be targeted with interventions to educate them not only about the importance of Pap exams in detecting cervical cancer, but also about strategies to decrease pain and embarrassment during exams. Nurses with less negative attitudes and experiences related to Pap exams would serve as role models to persuade women to have Pap exams, thus increasing the uptake rate of Pap exams in Taiwan.

• 한국체육학회지인문사회과학편
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• 제57권5호
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• pp.269-279
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• 2018

본 연구의 목적은 한국 암환자들의 근력운동 빈도, 근력, 그리고 건강관련 삶의 질과의 관계를 조사하는 것이다. 이를 위해 2014~2016년 국민건강영양조사 자료를 통합하여, 총 647명의 암환자들의 주당 근력운동 빈도, 악력, 건강관련 삶의 질의 관계를 복합표본 일반선형모형과 로지스틱 회귀분석 방법을 이용하여 분석하였다. 분석결과, 근력운동빈도가 주당 0~1일인 암환자들은 5일 이상인 암환자들에 비해(0.852±0.016 vs. 0.890±0.020 ; p=0.006), 상대 악력이 낮은 암환자들은 높은 그룹에 비해 (0.850±0.018 vs. 0.911±0.016; p<0.001) 건강관련 삶의 질 지수 (EQ-5D index) 가 유의하게 낮게 나타났다. 또한, 주당 근력운동 빈도가 0~1일인 암환자들은 5일 이상인 암환자들에 비해 운동능력에 문제가 생길 확률이 4.07배 (95% CI=1.31-12.63), 상대 악력이 낮은 그룹은 높은 그룹에 비해 운동능력에 문제가 생길 확률이 4.94배 (95% CI=2.14-11.41), 일상생활에서는 5.18배 (95% CI=1.56-17.14), 통증/불편에서는 2.46배 (95% CI=1.33-4.55) 증가했다. 본 연구결과를 통해 암환자들의 근력운동 빈도와 근력이 건강관련 삶의 질과 유의한 관계에 있는 것으로 나타났으며, 꾸준한 근력운동으로 인한 근력향상은 암환자들의 삶의 질 관리에 큰 도움이 될 것으로 사료된다.

• Safety and Health at Work
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• 제10권1호
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• pp.39-46
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• 2019

Background: As of now, the impact of low back pain (LBP) and its chronic state, chronic low back pain (CLBP), on mental health-related quality of life (HRQOL) has never been investigated among police officers. The present investigation aims at studying this relationship using a biopsychosocial model. Methods: Between May and October 2014, a Web-based cross-sectional study was conducted among Quebec police officers (Quebec, Canada). Mental HRQOL was measured using the role emotional (RE) and the mental health (MH) domains of the SF-12v2 Health Survey. The impact of CLBP on mental HRQOL (as opposed to acute/subacute LBP or no LBP) was studied with a multivariate linear regression model. Results: Of the 3,589 police officers who participated in the study, 1,013 (28.4%) reported CLBP. The mean age of respondents was $38.5{\pm}8.7years$, and 32.0% were females. The RE (44.1/100) and MH (49.0/100) mean scores of the CLBP group were comparable with the scores found in populations suffering from cancer or heart diseases. Compared to officers without LBP, the presence of CLBP was significantly associated with lower RE (${\beta}$: -0.068; p = 0.003) and MH (${\beta}$: -0.062; p = 0.002) scores. These relationships were not found in the acute/subacute LBP group. Conclusion: Our results underscore how frequent CLBP is among police officers and how burdensome it is. Considering the importance of good physical and mental health for this occupational population, police organizations should be aware of this issue and contribute to the efforts toward CLBP prevention and management in the workplace.

• 사회복지연구
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• 제42권2호
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• pp.419-441
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• 2011

본 연구는 암환자의 심리사회적 고통에만 초점을 두는 기존의 병리적 관점에서 벗어나 생존을 위협하는 암이라는 외상적 경험 속에서 얻게 되는 긍정적 변화와 성장을 검토하고 이에 대한 예측 요인을 분석하여 그 결과를 바탕으로 암환자의 외상후성장을 도모할 수 있는 임상적 개입에 대한 기초 자료를 제공하는 것을 목적으로 하였다. 이를 위해 연구 참여에 동의한 암환자 206명을 연구대상으로 설문조사를 실시하였으며 암환자의 외상후성장에 대한 예측요인을 검토하기 위해 인구사회학적 변인, 질병관련 변인, 대처, 사회적 지지를 독립변인으로 하여 연구모형을 구성하고 위계적 회귀분석을 통해 자료를 분석하였다. 조사 결과 암환자들의 외상후성장에 대한 주 영향요인으로 대처, 사회적 지지가 도출되었다. 이중 대처의 하위요인인 긍정적 재구조화가 암환자의 외상후성장에 대한 가장 강력한 예측요인으로 밝혀졌으며 이러한 결과를 토대로 사회복지적 함의와 후속연구에 대한 제언을 제시하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5381-5384
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• 2012

Background and Aim: Cholangiocarcinoma (CCA) is an uncommon malignancy of the bile duct, occurring in nearly 2 out of 100,000 people. It is a type of adenocarcinoma that originates in the mucous glands of the epithelium, or surface layers of the bile ducts. The aim of this study was to evaluate the clinical features, diagnostic results and factors associated with survival, morbidity and mortalityof cholangiocarcinoma cases in Iranian patients. Method: In this retrospective study the hospital medical records of 283 patients with a primary or final diagnosis of cholangiocarcinoma who had been admitted to gastroenterology ward of our hospital from 2004 to 2011 were retrospectively reviewed. Results: 283 patients (180 male, 63%, and 103 female, 38.6%) with a mean age of $59.7{\pm}14.4$ years were studied. The most frequent symptoms were painless jaundice (190, 66.9%), abdominal pain (77, 27%), pruritus 133 (46.8%) and weight loss (169, 59.5%). The most frequent associated risk factors and diseases were as follows: gallstones (72, 25.4%), diabetes (70, 24.6%), HBV infection (52 (18.3%), HCV infection 43 (15%), primary sclerosing cholangitis (16, 5.6%) and smoking (120, 42.3%). The most frequent type of cholangiocarcinoma in ERCP and MRCP was hilar. The mean survival time was $7.42{\pm}5.76$ months. Conclusion: The mean survival time in our study was lower than one year. Moreover the most frequent risk factors and associated diseases were smoking, gallstones and diabetes. Painless jaundice, abdominal pain and weight loss were the most clinical features related to cholangiocarcinoma. Additionally survival time did not correlate with risk factors, associated diseases and clinical presentations, but was linked to biliary metallic stenting and surgery.

• Journal of Gastric Cancer
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• 제19권1호
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• pp.49-61
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• 2019

Purpose: The perigastric vagus nerve may play an important role in preserving function after gastrectomy, and intraoperative neurophysiologic tests might represent a feasible method of evaluating the vagus nerve. The purpose of this study is to assess the feasibility of neurophysiologic evaluations of the function and viability of perigastric vagus nerve branches during gastrectomy. Materials and Methods: Thirteen patients (1 open total gastrectomy, 1 laparoscopic total gastrectomy, and 11 laparoscopic distal gastrectomy) were prospectively enrolled. The hepatic and celiac branches of the vagus nerve were exposed, and grabbing type stimulation electrodes were applied as follows: 10-30 mA intensity, 4 trains, $1,000{\mu}s/train$, and $5{\times}$frequency. Visible myocontractile movement and electrical signals were monitored via needle probes before and after gastrectomy. Gastrointestinal symptoms were evaluated preoperatively and postoperatively at 3 weeks and 3 months, respectively. Results: Responses were observed after stimulating the celiac branch in 10, 9, 10, and 6 patients in the antrum, pylorus, duodenum, and proximal jejunum, respectively. Ten patients responded to hepatic branch stimulation at the duodenum. After vagus-preserving distal gastrectomy, 2 patients lost responses to the celiac branch at the duodenum and jejunum (1 each), and 1 patient lost response to the hepatic branch at the duodenum. Significant procedure-related complications and meaningful postoperative diarrhea were not observed. Conclusions: Intraoperative neurophysiologic testing seems to be a feasible methodology for monitoring the perigastric vagus nerves. Innervation of the duodenum via the celiac branch and postoperative preservation of the function of the vagus nerves were confirmed in most patients.