• BMB Reports
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• v.29 no.3
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• pp.200-204
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• 1996

Nerve growth factor (NGF) is literally known to promote neural differentiation and survival in several peripheral and central neurons. Thus, it is Widely believed that NGF may serve as a therapeutic agent for many types of neuronal diseases. One of the mechanisms suggested to explain the protective role of NGF is that the trophic factor can prevent the increase of intracellular calcium ions which might be responsible for neural death. To examine whether or not the calcium hypothesis works even under pathological conditions, we applied NGF to cultures deprived of glucose. Surprisingly, what was observed here is that NGF rather promoted cell death under a glucose-deprived condition. What we call the NGF paradox phenomenon occurred in a calcium concentration-dependent manner, indirectly suggesting that NGF might increase intracellular calcium ions in cells deprived of glucose. This suggestion is further supported by the fact that nifedipine, a well-known L-type calcium channel blocker, could block the cell death potentiated by NGF. Here it is still premature to propose the complete mechanism underlying the NGF paradox phenomenon. However, this study certainly indicates that NGF as a therapeutic agent for neuronal diseases should be carefully considered before use.

• The Journal of Internal Korean Medicine
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• v.11 no.2
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• pp.137-147
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• 1990

I studied some important medical liter atures in order to examine the cause of Aphasia and found out some facts as follows : 1. Hwang Je Nae Kgong(黃帝內經) is more referred exogenous causes of disease of Aphasia than endogenous causes of disease. 2. Among many causes of Aphasia, exogenous causes of disease was cinsidered to be most common in Soh Shi Je Byong Won Hu chong Rhon(巢氏諸病源喉總論), which has had a wide influence down the ages. 3. Chon Keum Yo Bang(千金要方), Chi Tae Bhi Yo(外臺秘要), Tae Pyong Song Hye Bang(太平聖惠方), Song Je Chong Rok(聖濟總綠). Bu In Yang Bang(婦人良方) and so forth had been quoted from Hwang Je Nae Kyong and Soh Shi Je Byong Won Hu Chong Ron(巢氏諸病源喉總論). 4. In the ming dynasty had been quoted non-exo-endogenous causes of disease and the Kinds of Aphasia and prescription. 5. In the Choeun dynasty and the Ching dynasty, exogenous causes of disease was confined to the quotation of the books referred to above as well, but endogenous causes of disease was developed. 6. Today is refered kidney and Aphasia. The cause of Aphasia obtained was as follows. The exogenous cause of disease is wind, wind and cold, wind and heat. The endogenous cause of disease is pregnancy, heart block of postpartum, weakness of heart and kidney, impairment of seven modes of emotions, stagnation of phlegm and phlegm-fire, hemorrhage. The non exo-endogenous causes of disease is sing ballads and call out.

• The Journal of Society for e-Business Studies
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• v.2 no.2
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• pp.89-113
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• 1997

Modeling methodology has been widely used for analysis and design of a information system. Specially, under the CALS environments, modeling approach is more important because the enterprise functions are inter-related and information sharing speeds up the business. In this paper, we suggest functional requirements about modeling methodology for CALS by surveying the IDEF0 and ARIS. The former is FIPS 183 and the latter is basic methodology of SAP/R3 which is world-wide ERP system. The proposed functional requirements include all semantics of IDEF0 and adds some features. The first is adding modeling components which are semantic representations. In addition to ICOMs, we add the time and cost component which is required to execute the function. The second is tracing mechanism. When we need some information, we drive the functions related with the information by reverse tracing of the function which produces the information as a output and input. Through the tracing, we find out the bottleneck process or high cost process. This approach guarantees the integrity of data by designating the data ownership. Finally, we suggest the final decomposition level. We call the final decomposed function into unit function which has only one output data. We can combine and reconstruct some of functions such as 'lego block' combination.

• Journal of Information Processing Systems
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• v.7 no.1
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• pp.173-186
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• 2011

Due to the disadvantages of signature-based computer virus detection techniques, behavior-based detection methods have developed rapidly in recent years. However, current popular behavior-based detection methods only take API call sequences as program behavior features and the difference between API calls in the detection is not taken into consideration. This paper divides virus behaviors into separate function modules by introducing DLLs into detection. APIs in different modules have different importance. DLLs and APIs are both considered program calling resources. Based on the calling relationships between DLLs and APIs, program calling resources can be pictured as a tree named program behavior resource tree. Important block structures are selected from the tree as program behavior features. Finally, a virus detection model based on behavior the resource tree is proposed and verified by experiment which provides a helpful reference to virus detection.

• Journal of KIISE:Computing Practices and Letters
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• v.5 no.2
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• pp.247-262
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• 1999

이동 컴퓨팅 환경의 특징은 대역폭의 제약과 잦은 접속의 단절이다. 앞으로 이동 컴퓨팅에 대한 요구는 증가할 것이며 이동 컴퓨팅 환경을 극복할 수 있고 동적으로 적응할 수 있는 서비스를 필요로 한다. RPC(Remote Procedure Call)는 동기적이며 믈록(block)상태를 유발시키는 통신 구조로 분산 응용 프로그램을 작성하기 위한 환경을 제공한다. M-RPC(Mobile RPC) 는 RPC를 이동 컴퓨팅 환경에 맞도록 확장한 것이다. MOM(Message Oriented Middleware)은 분산 통신을 위한 미들웨어로서 분산 프로세스들간에 동기적 또는 비동기적 상호 작용을 지원하는 peer-to-peer 분산 컴퓨팅 모형으로 특징지워진다. 본 논문은 기존 MOM 시스템을 기반으로 하여 이동 컴퓨팅 환경을 지원하는 M-MOM(Mobile-MOM) 시스템을 제안하고 자바 언어로 구현하여 성능을 평가한다. M-MOM 환경에서 이동 호스트(mobile host)에서 실행되는 응용 프로그램과 고정 호스트(fixed host)에서 실행되는 메시지 큐 관리자는 베이스 스테이션(Base Station)에서 실행되는 메시지 에이전트를 통해 메시지 큐 관리자와 동적으로 연결된다. 비동기적인 서비스를 지원하는 M-MOM은 동기적인 서비스만을 지원하는 M-RPC 보다 이동 컴퓨팅 환경을 보다 효과적으로 극복할 수 있는 서비스를 지원한다.

• Korean Journal of Agricultural Science
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• v.6 no.2
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• pp.112-118
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• 1979

This experiment was carried out to evaluate the effect of potassium application level for pasture management in Chungnam area. The results obtained were as follows. 1. The seedling establishment of pasture species was slightly depressed by high potassium application. 2. By increasing potassium application level, the winter hardiness of pasture species increased. 3. The forage yield of pasture species was more increased in legume single seeding than grass single and mixed seeding by higher potassium application. 4. The $K_2O$ content in forage was increased markedly by increasing potassium application level on grass single block. 5. The results obtained from this experiment indicated that potassium application level much effective on the winter hardiness of pasture species and forage yield specially in legume single seeding and adequate amount of potassium would be 20kg per 10a in this area.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.6
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• pp.25-35
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• 1998

The control system architecture in switching systems have undergone numerous changes to provide various call processing capability needed in telecommunication services. During call processing in a distributed switching control environment, the delay effect due to communication among main processors or peripheral controllers is one of the limiting factors which affect the system performance. In this paper, we propose a performance model for an IPC(Inter Processor Communication) interface hardware block which is required on the ATM cell-based message processing in a distributed ATM exchange system, and analyze the primary causes which affect the processor performance through the simulation. Consequently, It can be shown that the local CPU of the several components(resources) related to the IPC scheme is a bottleneck factor in achieving the maximum system performance from the simulation results, such as the utilization of each processing component according to the change of the input message rate, and the queue length and processing delay according to input message rate. And we also give some useful results such as the maximum message processing capacity according to the change of the performance of local CPU, and the local CPU maximum throughput according to the change of average message length, which is applicable as a reference data for the improvement or expansion of the ATM control system.

• Journal of KIISE
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• v.44 no.3
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• pp.232-238
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• 2017

Application response time is critical to end-user response time in Android smartphones. Due to the plentiful resources of recent smartphones, storage I/O response time becomes a major key factor in application response time. However, existing storage I/O trace tools for Android and Linux give limited information only for a specific I/O layer which makes it difficult to combine I/O information from different I/O layers, because not helpful for application developer and researchers. In this paper, we propose a novel storage I/O trace tool for Android, called AIOPro (Android I/O profiler). It traces storage I/O from application - Android platform - system call - virtual file system - native file system - page cache - block layer - SCSI layer and device driver. It then combines the storage I/O information from I/O layers by linking them with file information and physical address. Our evaluations of real smartphone usage scenarios and benchmarks show that AIOPro can track storage I/O information from all I/O layers without any data loss under 0.1% system overheads.

• Archives of Plastic Surgery
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• v.32 no.4
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• pp.479-484
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• 2005

Raynaud's syndrome causes discolorization, ischemic claudication(pain) and necrosis of the digits through insufficiency in the circulation which is induced by intermittent spasms of the digital arteries. From January, 2002 to December, 2004, 10 patients were surgically treated for Raynaud's syndrome. 9 patients were female and 1 patient was male. 2 patients showed unilateral involvement, 8 patients were operated on both hands. 6 patients had necrotic changes on the finger tips due to the disease. Ages ranged from 21 to 60 with an average of 39.1. Ischemic pain, discolorization, and cold intolerance of the digits were the common symptoms. All patients were evaluated with color doppler before the surgery. Two different procedures were applied according to the severity of the disease: Patients with decreased circulation received, what we call a limited digital sympathectomy, i.e. stripping of the adventitia of the ulnar, radial and common digital arteries. An extended procedure, radical digital sympathectomy, was performed on patients with a complete block of circulation. Stripping of the adventitia in these patients also involved the proper digital arteries. Symptoms like discolorization, ischemic pain, and cold intolerance improved immediately after the surgery. The patients did not suffer from pain even with exposure to cold weather. We conclude that digital sympathectomy could improve the symptoms in Raynaud's patients who do not respond to conservative treatment such as calcium channel blocker and other vasodilators.

• The KIPS Transactions:PartC
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• v.10C no.1
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• pp.77-86
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• 2003

This paper describes the new method for Internet multicast routing protocols using MPLS (Multiprotocol Label Switching) networks. Internet multicast routing protocols are divided into three categories in terms if tree types and tree characteristics : a shortest path tree a shared tree and hybrid tree types. MPLS should support various multicast mechanisms because of extremely different IP multicast architectures, such as uni-/bi-directional link, Flooding/prune tree maintenance mechanism. the existence of different tree types with the same group, etc. There are so many problems over MPLS multicast that the solutions can't be easily figured out. In this Paper, we make a few assumptions on which the solutions of IP multicast routing protocols over MPLS networks are given. A broadcasting label is defined for the shortest path tree types. Cell interleaving problems of the shared tree types is solved by using block-based transmission mechanism. Finally, the existing hybrid-type multicast routing protocol is reasonably modified Shortest Path tree type to support MPLS multicast. It has been shown that these modifications give better performance (transmission delay) than the orignal method.