• 임상간호연구
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• 제18권2호
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• pp.307-316
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• 2012

Purpose: The purpose of this study was to develop and test psychometric properties the Korean version of the End-Stage Renal Disease Adherence Questionnaire (KESRD-AQ). The ESRD-AQ, a 46-item, multidimensional, self-administrated questionnaire which was developed to assess treatment adherence to hemodialysis (HD) attendance, medications, fluid restrictions, and diet prescription among patients on maintenance hemodialysis, has been validated. Methods: The KESRD-AQ was developed by performing both translation and backtranslation. The content validity and test- retest reliability of the KESRD-AQ were evaluated by establishing item-level content validity index (I-CVI) and intra-class correlation coefficients (ICC), respectively. Construct validity was assessed by adopting a known-group analysis comparing adheres and non-adherers using Mann-Whitney U Test. Results: 41 Korean-American patients with ESRD on HD from 3 outpatient dialysis centers in California participated in the study. The KESRD-AQ showed excellent content validity (average I-CVI=.96) and test-retest reliability (ICC=.917, p=.004). The construct validity indicated that the KESRD-AQ distinguished adheres and non-adheres (p=.02~.047). Conclusion: The KESRD-AQ is a valid and reliable instrument to measure treatment adherence.

• Geomechanics and Engineering
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• 제10권5호
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• pp.689-707
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• 2016

Soil stabilization is one of the useful method of ground improvement for soil with low bearing capacity and high settlement and unrequired swelling potential. Generally, the stabilization is carried out by adding some solid materials. The main objective of this research was to investigate the feasibility of stabilization of organic soils and sewage sludge to obtain low cost alternative embankment material by the addition of two different slags. Slags were used as a replacement for weak soil at ratios of 0%, 25%, 50%, 75% and 100%, where sewage sludge and organic soil were blended with slags separately. The maximum dry unit weights and the optimum water contents for all soil mixtures were determined. In order to investigate the influence of the slags on the strength of sewage sludge and organic soil, and to obtain the optimal mix design; compaction tests, the California bearing ratio (CBR) test, unconfined compressive strength (UCS) test, hydraulic conductivity test (HCT) and pH tests were carried out on slag-soil specimens. Unconfined compressive tests were performed on non-cured samples and those cured at 7 days. The test results obtained from untreated specimens were compared to tests results obtained from soil samples treated with slag. Laboratory tests results indicated that blending slags with organic soil or sewage sludge improved the engineering properties of organic or sewage sludge. Therefore, it is concluded that slag can be potentially used as a stabilizer to improve the properties of organic soils and sewage sludge.

• Child Health Nursing Research
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• 제27권1호
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• pp.13-23
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• 2021

Purpose: This study aimed to develop a mobile-based self-management health alarm (MSHA) program for modifying obese children's lifestyle based on the information-motivation-behavioral skills (IMB) model and to test its feasibility. Methods: A methodological study for the development of the MSHA program and pilot study with a one-group pretest-posttest design for feasibility testing was conducted. The MSHA program was designed to provide obesity-related information (I), monitor daily diet and exercise, provide motivational text messages (M), and enhance healthy diet and exercise skills (B) via a mobile-based web platform. In the feasibility test, six obese children participated in the 4-week program, and the number of days per week that they achieved their goals and differences in metabolic components were assessed. Data were analyzed using descriptive statistics and the Wilcoxon signed-rank test. Results: Participants successfully achieved their diet and exercise goals≥5 days per week. Body mass index (z=-1.99, p=.046), waist circumference (z=-2.20, p=.028), and triglyceride levels (z=-2.21, p=.027) significantly decreased. Conclusion: The MSHA program showed positive effects on health behaviors and metabolic syndrome risk. The program may be effective in improving metabolic syndrome in obese children by promoting self-health management behaviors.

• 대한수의사회지
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• 제18권4호
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• pp.9-14
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• 1982

대전시 근교의 18개 목장에서 착유우 167두를 대상으로 C.M.T.법에 의해 유방염조사를 실시하여 양성우의 유즙으로부터 Staphylococcus 7주를 분리하였다. 이를 유방염치료에 있어 보다 개선된 대책을 강구하기 위하여 시판되고 있는 15종의 항균성제제에 대한 감수성시험을 실시한 바 그 성적을 다음과 같이 요약한다. 1. 분리된 Staphylococcus군에 있어 No.3,5,7수는 전항균성제제에, No.1,6주는 14제제에, No.2주는 13제제에, No.4주는 4제제에 대해서 감수성을 나타냈다. 2. 같은 항균성제제를 지속적으로 사용하거나, 다수제제를 사용할 경우 그 빈도가 잦을 수록 감수성이 약해지는 동시에 내성이 형성되었다. 3. 유방염 발생에 있어 항균성제제에 대한 감수성시험을 선행실시함으로서 치료법을 합리적으로 개선할 수 있을 것이다. 4. 항균성이 강한 제제를 선정하여 자주 교체사용하는 방법을 권장하고저 한다.

• 근관절건강학회지
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• 제8권2호
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• pp.278-286
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• 2001

With the aging of society a great deal of interest is being placed on the value of longitudinal data in evaluating physiological losses. We present data on test-one/test-two reliability and reproducibility for measures of training, bone density from a longitudinal study of master athletes. Fifty-two males (mean age at test $1=58.2{\pm}9.8\;years$) and thirty-two females ($54.4{\pm}8.8\;years$) were selected from the study population. Bone mineral density was determined using DEXA (Hologic 1500). The characteristics of the subjects are presented below as $means\;{\pm}\;S.D$. The data was imported into the Statistical Package for the Social Science (SPSS 9.0, Chicago, IL). Paired t-tests were performed between visit 1 and visit 2 in subjects. Pearson correlations were performed. The results of this study indicate the measures of training history, body mass and bone density are reasonably stable and reproducible. We conclude that body composition and bone density parameters are stable and reproducible over time in active older subjects. Physiologic measures in master athletes are fairly stable, and reproducible over time Longitudinal studies investigating age-related changes in master athletes need to be conducted on a time schedule of greater than two years.

• Structural Engineering and Mechanics
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• 제82권6호
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• pp.735-745
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• 2022

The suspension thyristor valve can generate tremendous vertical acceleration responses in layers and large tension forces in hangers. A shaking table test of a scaled-down model of thyristor valves suspended on a hall building is performed to qualify the risk of vertical uplift of two representative types of valves, the chain valve and the rigid valve. Besides, an analytical model is established to investigate the source of the slackening of hangers. The test results show that the valves frequently experience a large vertical acceleration response. The soft spring joint can significantly reduce acceleration, but is still unable to prevent vertical uplift of the chain valve. The analytical model shows a stiffer roof and inter-story connection both contribute to a higher risk of vertical uplift for a rigid valve. In addition, the planar eccentricity and short hangers, which result in torsional motion of the valve, increase the possibility of vertical uplift for a chain valve. Therefore, spring joints with additional viscous dampers and symmetric layout in each layer are recommended for the rigid and chain valve, respectively, to prevent the uplift of valves.

• 농업과학연구
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• 제10권2호
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• pp.193-199
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• 1983

대전근교(大田近郊)의 목장(牧場)에서 자유중인 유우(乳牛)를 대상(對象)으로 CMT법(法)에 의하여 유방염(乳房炎)으로 판정(判定)된 양성우(陽性牛)의 유즙(乳汁)으로부터 분리(分離)한 Staphylococcus aureus를 공시(供試)하여 유방염치료(乳房淡治療)에 있어 보다 개선(改善)된 방법(方法)을 모색(模索)하기 위하여 시판(市販)되고 있는 복합처방(複合處方)된 항균제(抗菌劑)를 선택(選擇)하여 내성시험법(耐性試驗法)을 개발(開發)할 목적(目的)으로 실시(實施)한 결과(結果)를 다음과 같이 요약(要約)한다. 1. 치료용(治療用) 항균제(抗菌劑)를 계속(繼續) 반복(反復)하여 사용(使用)하게되면 차등(差等)있는 내성(耐性)을 나타내었다. 2. Rifamastene, Neo-cillin은 다같이 4회(回)까지 Abimasten-100, Neo-Masti, Special formula, Mastalone은 6회(回)까지 약(弱)한 내성(耐性)을 나타내었다. 3. Tardomyocel-L는 6회(回)까지 내성(耐性)이 거의 나타나지 않았다. 4. 내성시험(耐性試驗)을 거처 선택(選擇)된 약제(藥齊)를 3일간격(日間隔)으로 교체사용(交替使用)할 것을 권장한다.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1994년도 교수 연수회(환경)
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• pp.431-438
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• 1994

As currently conducted, standard rodent bioassays do not provide sufficient information to assess carcinogenic risk to humans at doses thousands of times below the maximum tolerated dose. Recent analyses indicate that measures of carcinogenic potency from these tests are restricted to a narrow range about the maximum tolerated dose and that information on shape of the dose-response is limited in experiments with only two doses and a control. Extrapolation from high to low doses should be based on an understanding of the mechanisms of carcinogenesis. We have postulated that administration of the maximum tolerated dose can increase mitogenesis which, in turn. increases rates of mutagenesis and, thus, carcinogenesis. The animal data are consistent with this mechanism, because about half of all chemicals tested are indeed rodent carcinogens, and about 40% of the positives are not detectably mutagenic. Thus, at low doses where cell killing does not occur, the hazards to humans of rodent carcinogens may be much lower than commonly assumed. In contrast, for high-dose exposures in the workplace, assessment of hazard requires comparatively little extrapolation. Nevertheless. permitted workplace exposures are sometimes close to the tumorigenic dose-rate in animal tests. Regulatory policy to prevent human cancer has primarily addressed synthetic chemicals, yet similar proportions of natural chemicals and synthetic chemicals test positive in rodent studies as expected from an understanding of toxicological defenses, and the vast proportion of human exposures are to natural chemicals. Thus, human exposures to rodent carcinogens are common. The natural chemicals are the control to evaluate regulatory strategies, and the possible hazards from synthetic chemicals should be compared to the possible hazards from natural chemicals. Qualitative extrapolation of the carcinogenic response between species has been investigated by comparing two closely related species: rats and mice. Overall predictive values provide moderate confidence in interspecies extrapolation; however, knowing that a chemical is positive at any site in one species gives only about a 50% chance that it will be positive at the same site in the other species.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2003년도 한국우주과학회보 제12권2호
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• pp.52-52
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• 2003

1996년 미국 버클리 대학의 Space Science Laboratory와 공동으로 고온 성간 물질의 관측에 대한 Conceptual Study로부터 시작되어 1998년 과학위성 1호의 주 탑재체로 선정되면서 본격적인 개발에 들어간 원자외선 분광기(FIMS: Far-ultraviolet IMaging Spectrograph)는 Engineering Model 개발, Qualification Model 개발, Flight Model의 개발 및 보정, 그리고 최종적으로 과학기술위성 1호 본체와의 조립 시험 및 환경시험을 거쳐 2003년 9월 26일 러시아의 플레세츠크에서 COSMOS-3M 발사체에 의해 발사된다. FIMS를 포함한 과학위성 1호는 현재 발사를 위해 러시아 현지에 이송되어 최종 시험을 진행 중이며, 발사 후 약 20일 가량은 위성의 운용 시험을 하게 되며, 이후 FIMS의 운용에 영향을 줄 수 있는 Out-gassing이 충분히 이루어진 후 FIMS의 Test 및 초기 운용이 이루어 진다. FIMS의 Detector로 사용되는 MCP(Micro Channel Plate)의 정상적 동작이 확인되면, 1년여에 걸쳐 FIMS의 주 임무인 원자외선 영역(900∼1750')의 은하계 전천 탐사를 수행하게 된다. 전천 탐사가 마무리 되면, 전천탐사의 결과를 바탕으로 개별 천체의 영상 및 분광 자료를 획득하게 되며, 동시에 원자외선 영역의 오로라 및 지구 대기광 측정을 수행한다.

• Korea-Australia Rheology Journal
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• 제21권4호
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• pp.213-223
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• 2009

Taylor-Couette flow (i.e., flow between concentric, rotating cylinders) has long served as a paradigm for studies of hydrodynamic stability. For Newtonian fluids, the rich cascade of transitions from laminar, Couette flow to turbulent flow occurs through a set of well-characterized flow states (Taylor Vortex Flow, wavy Taylor vortices, modulated wavy vortices, etc.) that depend on the Reynolds numbers of both the inner and outer cylinders ($Re_i$ and $Re_o$). While extensive work has been done on (a) the effects of weak viscoelasticity on the first few transitions for $Re_o=0$ and (b) the effects of strong viscoelasticity in the limit of vanishing inertia ($Re_i$ and $Re_o$ both vanishing), the viscoelastic Taylor-Couette problem presents an enormous parameter space, much of which remains completely unexplored. Here we describe our recent experimental efforts to examine the effects of drag reducing polymers on the complete range of flow states observed in the Taylor-Couette problem. Of particular importance in the present work is 1) the rheological characterization of the test solutions via both shear and extensional (CaBER) rheometry, 2) the wide range of parameters examined, including $Re_i$, $Re_o$ and Elasticity number E1, and 3) the use of a consistent, conservative protocol for accessing flow states. We hope that by examining the stability changes for each flow state, we may gain insights into the importance of particular coherent structures in drag reduction, identify simple ways of screening new drag reducing additives, and improve our understanding of the mechanism of drag reduction.