• Journal of Information Processing Systems
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• v.10 no.1
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• pp.103-118
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• 2014

Over the last couple of years, traditional VANET (Vehicular Ad Hoc NETwork) evolved into VANET-based clouds. From the VANET standpoint, applications became richer by virtue of the boom in automotive telematics and infotainment technologies. Nevertheless, the research community and industries are concerned about the under-utilization of rich computation, communication, and storage resources in middle and high-end vehicles. This phenomenon became the driving force for the birth of VANET-based clouds. In this paper, we envision a novel application layer of VANET-based clouds based on the cooperation of the moving cars on the road, called CaaS (Cooperation as a Service). CaaS is divided into TIaaS (Traffic Information as a Service), WaaS (Warning as a Service), and IfaaS (Infotainment as a Service). Note, however, that this work focuses only on TIaaS and WaaS. TIaaS provides vehicular nodes, more precisely subscribers, with the fine-grained traffic information constructed by CDM (Cloud Decision Module) as a result of the cooperation of the vehicles on the roads in the form of mobility vectors. On the other hand, WaaS provides subscribers with potential warning messages in case of hazard situations on the road. Communication between the cloud infrastructure and the vehicles is done through GTs (Gateway Terminals), whereas GTs are physically realized through RSUs (Road-Side Units) and vehicles with 4G Internet access. These GTs forward the coarse-grained cooperation from vehicles to cloud and fine-grained traffic information and warnings from cloud to vehicles (subscribers) in a secure, privacy-aware fashion. In our proposed scheme, privacy is conditionally preserved wherein the location and the identity of the cooperators are preserved by leveraging the modified location-based encryption and, in case of any dispute, the node is subject to revocation. To the best of our knowledge, our proposed scheme is the first effort to offshore the extended traffic view construction function and warning messages dissemination function to the cloud.

• 한국전산유체공학회:학술대회논문집
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• 2003.10a
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• pp.75-76
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• 2003

Direct numerical simulation results of aeolian tones generated by a two-dimensional obstacle (circular cylinder, square cylinder, NACA0012 airfoil) in a uniform flow are presented and the generation and propagation mechanisms of the sound are discussed. The unsteady compressible Navier-Stokes equations are solved by a highly-accurate finite difference scheme over the entire region from near to far fields. The direct numerical simulation results are also compared with the results obtained by Curle's acoustic analogy.

• Journal of Aerospace System Engineering
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• v.15 no.5
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• pp.50-59
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• 2021

The need for risk based safety management has been highlighted in accordance with the growth of aviation industry and public interest in aviation safety. Maintenance, Repair and Overhaul (MRO) in aviation industry is defined to guarantee the safety and reliability. Therefore, state's Civil Airworthiness Authority (CAA) has established safety oversight system dedicated for the development of a healthy MRO industry. The study proposed a risk based oversight system considering Korean environment. Based on literature review including analysis of International Civil Aviation Organization guidance and advance system, we identified two organization risks. Organization complexity can be evaluated in accordance with how large the organization is and how complicated the service they provide are. Organization profile is the organization's characteristic related with safety. This study contributes to improving the process of identifying risk of organization and focusing surveillance capabilities on risk areas for efficient management of CAA's resources.

• Korean Circulation Journal
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• v.54 no.9
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• pp.577-586
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• 2024

Background and Objectives: Kawasaki disease (KD) is an acute vasculitis that primarily affects children under age 5 years. Approximately 20-25% of untreated children with KD and 3-5% of those treated with intravenous immunoglobulin therapy develop coronary artery aneurysms (CAAs). The prevalence of CAAs is much higher in male than in female patients with KD, but the underlying factors contributing to susceptibility to CAAs in patients with KD remain unclear. This study aimed to identify sex-specific susceptibility loci associated with CAAs in KD patients. Methods: A sex-stratified genome-wide association study (GWAS) was performed using previously obtained GWAS data from 296 KD patients and a new replication study in an independent set of 976 KD patients by comparing KD patients without CAA (controls) and KD patients with aneurysms (internal diameter ≥5 mm) (cases). Results: Six male-specific susceptibility loci, PDE1C, NOS3, DLG2, CPNE8, FUNDC1, and GABRQ (odds ratios [ORs], 2.25-9.98; p=0.00204-1.96×10^-6), and 2 female-specific susceptibility loci, SMAD3 (OR, 4.59; p=0.00016) and IL1RAPL1 (OR, 4.35; p=0.00026), were significantly associated with CAAs in patients with KD. In addition, the numbers of CAA risk alleles additively contributed to the development of CAAs in patients with KD. Conclusions: A sex-stratified GWAS identified 6 male-specific (PDE1C, NOS3, DLG2, CPNE8, FUNDC1, and GABRQ) and 2 female-specific (SMAD3 and IL1RAPL1) CAA susceptibility loci in patients with KD.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.3
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• pp.72-77
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• 2017

This paper focuses on the development of a supporting S/W tool for the automated design of an automotive press trim die. To define the die design process based on automation, we analyze the press die design process of the current industry and group repetitive works in the 3D modeling process. The proposed system consists of two modules, namely the template models of the trim steel parts and UI function for their auto-positioning. Four kinds of template models are developed to adapt to various situations and the rules of the interaction formula which are used for checking and correcting the directions of the datum point, datum curve, datum plane are implemented to eliminate errors. The system was developed using CATIA Knowledgeware, CAA(CATIA SDK) and Visual C++, in order for it to function as a plug-in module of CATIA V5, which is one of the major 3D CAD systems in the manufacturing industry. The developed system was tested by applying it to various panels of current automobiles and the results showed that it reduces the time-cost by 74% compared to the traditional method.

• Genomics & Informatics
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• v.19 no.4
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• pp.38.1-38.7
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• 2021

Kawasaki disease (KD) is an acute pediatric vasculitis that affects genetically susceptible infants and children. To identify coding variants that influence susceptibility to KD, we conducted whole exome sequencing of 159 patients with KD and 902 controls, and performed a replication study in an independent 586 cases and 732 controls. We identified five rare coding variants in five genes (FCRLA, PTGER4, IL17F, CARD11, and SIGLEC10) associated with KD (odds ratio [OR], 1.18 to 4.41; p = 0.0027-0.031). We also performed association analysis in 26 KD patients with coronary artery aneurysms (CAAs; diameter > 5 mm) and 124 patients without CAAs (diameter < 3 mm), and identified another five rare coding variants in five genes (FGFR4, IL31RA, FNDC1, MMP8, and FOXN1), which may be associated with CAA (OR, 3.89 to 37.3; p = 0.0058- 0.0261). These results provide insights into new candidate genes and genetic variants potentially involved in the development of KD and CAA.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.3
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• pp.147-154
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• 2018

This paper focuses on the development of a support system that can rapidly generate the design data of a hot-form die with cooling channels, commonly known as hot stamping technology. We propose a new process for designing hot-form dies based on our (automated) system, whose main features are derived from the analysis of the design requirements and design process in the current industry. Our design support system consists of two modules, which allow for the generation of a 3D geometry model and its 2D drawings. The module for 3D modeling automation is implemented as a type of CATIA template model based on CATIA V5 Knowledgeware. This module automatically creates a 3D model of a hot-form die, including the cooling channels, that depends on the shape of the forming surface and the number of STEELs (subsets of die product) and cooling channels. It also allows for both the editing of the positions and orientations of the cooling channels and testing for the purpose of satisfying the constraints on the distance between the forming surface and cooling channels. Another module for the auto-generation of the 2D drawings is being developed as a plug-in using CAA (CATIA SDK) and Visual C++. Our system was evaluated using the S/W test based on a user defined scenario. As a result, it was shown that it can generate a 3D model of a hot form die and its 2D drawings with hole tables about 29 times faster than the conventional manual method without any design errors.

• 유체기계공업학회:학술대회논문집
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• 2001.11a
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• pp.76-80
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• 2001

Unsteady compressible Euler equation is solved and the high-order, high-resolution numerical solver, physical boundary condition, adaptive nonlinear artificial dissipation model and conformal mapping are applied to computation of steady transonic flow and unsteady acoustics. The acoustic characteristics of axi-symmetric duct and two dimensional straight/S channel are studied and the computation results shows good agreements with linear analysis. In transonic case, local time stepping and canceling-the-residual techniques are used for convergence acceleration. The aspect of flow and acoustics in S-channel and the Pattern of noise radiation is changed by inflow Mach no. and static pressure at fan-face.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2013.04a
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• pp.166-171
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• 2013

In this study, low noise designs of a Savonius wind turbines are numerically investigated. From a previous study, it was found that the high harmonic components whose fundamental frequency is higher than the BPF were found to be dominant in noise spectrum of a Savonius wind turbine. On a basis of this observation, S-shaped blade tip is proposed as a low design factors that decrease wind turbine noise by inducing phase differences in vortex shedding. The conventional Savonius and S-shaped turbines are investigated using Hybrid CAA method where flow field around the turbine are computed using CFD techniques and the radiated noise are predicted by applying acoustic analogy to the computed flow data. Noise reductions by these design factors are confirmed by comparing the predicted noise levels from these turbines.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.13
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• pp.5249-5252
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• 2014

Nogo protein, encoded by gene reticulon-4 (RTN4), includes three major isoforms by different splicing, named Nogo-A Nogo-B and Nogo-C. Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. RTN4 single nucleotide polymorphisms (SNPs) can influence the efficiency of transcription and translation thus being related with an individual's predisposition to cancer. The CAA insertion/deletion polymorphism (rs34917480) within RTN4 3'-UTR has been reported to be associated with many cancer types. In order to investigate the relationship between this polymorphism and susceptibility to non-small cell lung cancer (NSCLC) in the Chinese population, we conducted the present case-control study including 411 NSCLC patients and 471 unrelated healthy controls. The genotype distributions were significantly different between cases and controls (p=0.014). We found that the del allele could significantly increase NSCLC risk (ins/ins vs ins/del: p=0.007, OR 1.46, 95%CI=1.11-1.93; dominant model: p=0.004, OR 1.47, 95%CI=1.13-1.92 and allele model: p=0.008, OR 1.35, 95%CI=1.08-1.67). This association was stronger in participants over 60 years old, males and smokers. We therefore conclude that the CAA insertion/deletion polymorphism (rs34917480) contributes to non-small cell lung cancer risk in Chinese population. Age, sex and environmental exposure are also related to carcinogenic effects of rs34917480.