• 대한화학회지
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• 제55권2호
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• pp.317-322
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• 2011

• 약학회지
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• 제11권3_4호
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• pp.36-38
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• 1967

One of the coumarin derivatives, (-) trans-khellactone was isolated from the roots of Angelica purpureafolia $C_{HUNG}$.

• 대한설비공학회지:설비저널
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• 제27권3호
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• pp.264-272
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• 1998

• 한국균학회지
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• 제21권1호
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• pp.28-37
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• 1993

섬유소 분해균인 P. verrculosum의 배양 여액으로부터 endo형 cellulase 인 CMCase IV를 정제하였다. CMCase IV는 13%의 탄수화물과 4.0의 pl값을 가진 산성, 당단백질이었다. CMCase IV의 SDSPAGE 상에서 분자량은 52 KDa이었으며, 효소 활성을 위한 최적 pH 및 온도는 5.0과 $50^{\circ}C$ 였다. CMCase IV를 CMC에 반응시 대부분 glucose와 cellobiose가 생산되었으며, 또한 동시에 transglycosylation 작용을 함께 갖는 것으로 사료되었다. Cellulase 활성 염색법(zymogram)을 통해서 P. verruculosum의 cellulase component가 배지 내에서 aggregation 되어있지 않음을 알 수 있었다. P. verruculosum mRNA의 in vitro 번역을 통하여 CMCase IV를 coding하는 번역산물이 동정 되었다.

• 대한화학회지
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• 제31권2호
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• pp.178-183
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• 1987

$VO_2^+$와 $[Mo_3O_4(H_2O)_9]^{4+}$의 산화반응에 대한 속도론을 $25^{\circ}C$에서 분광광도법으로 연구하였다. 과량의 $VO_2^+$에서 $[Mo_3O_4(H_2O)_9]^{4+}$의 산화반응은 $Mo^{IV}_3+6V^V{\rightleftarrows}3Mo^{IV}+6V^IV}$이다. 반응에 대한 관찰된 속도상수, $k_{obs}$는 수소이온과 $VO^{2+}$에 의존한다. $[Mo_3O_4(H_2O)_9]^{4+}$와 $VO_2^+$의 산화-환원반응에 대한 상세한 메카니즘이 제시되며 이에 대하여 논의된다.

• Journal of Trauma and Injury
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• 제26권4호
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• pp.255-260
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• 2013

Purpose: For the treat hypothermia patients, active warming might be needed. In most emergency departments, IV warm saline infusion is used for treatments. However, during IV warm saline infusion, heat loss from the warm saline may occur and aggravate hypothermia. Thus, in this study, we conducted an experiment on conserving heat loss from warm saline by using a simple method. Methods: Four insulation methods were used for this study. 1) wrapping the set tube for the administration of the IV fluid with a cotton bandage, 2) wrapping the set tube for the administration of the IV fluid with a cotton bandage with aluminum foil, 3) wrapping the warm saline bag and tube with a cotton bandage, and 4) wrapping the warm saline bag and tube with a cotton bandage with aluminum foil. Intravenous fluid was preheated to a temperature between $38-40^{\circ}C$. The temperatures of the saline bag temperature and the distal end of the IV administration set were measured every ten minutes for an hour. The infusion rate was 1000 cc/hr, and to obtain an accurate infusion rate, we used an infusion pump. Results: The mean initial temperature of the saline bag was $39.11^{\circ}C$. An hour later, the fluid temperature at the distal end of the fluid temperature ranged from $39.11^{\circ}C$ to $34.3^{\circ}C$. Without any insulation, the initial temperature of the pre-heated warm saline, $39^{\circ}$ had decreased to $34.8^{\circ}C$ after having been run through the 170-cm-long IV administration tube, and after 1-hour, the temperature was $29.63^{\circ}C$. As we expected, heat loss was prevented most by wrapping both the saline bag and the IV administration set with a cotton bandage and aluminum foil. Conclusion: Wrapping both the saline bag and the IV administration set with a cotton bandage and aluminum foil can prevent heat loss during IV infusion in Emergency departments.

• BMB Reports
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• 제30권2호
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• pp.95-100
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• 1997

Two kinds of cDNA encoding mouse $Gal{\beta}$1,3(4)GlcNAc ${\alpha}$2,3-sialyltransferase (mST3Gal III) and $Gal{\beta}$1,4(3)GlcNAc ${\alpha}$2,3-sialyltransferase (mST3Gal IV) were isolated from mouse brain cDNA library by means of a PCR-based approach. The cDNA sequences included an open reading frame coding for proteins of 374 and 333 amino acids, respectively, and the primary structure of these enzymes suggested a putative domain structure consisting of four regions, like that in other glycosyltransferases. The deduced amino acid sequences of mST3GaI III and IV showed a 98% and 89% identity with rat ST3GaI III and human ST3Gal IV, respectively. Northern analysis indicated that the expression of mST3Gal III mRNA was abundant in heart, liver and adult brain, while that of mST3GaI IV mRNA was detected in all tissues tested except for testis, but the level was the highest in liver. Soluble forms of mST3GaI III and IV transiently expressed in COS cells exhibited enzyme activity toward acceptor substrates containing the terminal either $Gal{\beta}$1,3GlcNAc or $Gal{\beta}$1,4GlcNAc sequences. The substrate preferences of both enzymes were stronger for tetrasaccharides than for disaccharides.

• 한국자기공명학회논문지
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• 제21권3호
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• pp.109-113
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• 2017

The hepatitis C virus (HCV) internal ribosome entry site (IRES) is an RNA structure located in the 5'-UTR of the HCV RNA genome. The HCV IRES consists of four domains I, II, III, and IV, where domains II - IV are recognized by 40S ribosomal subunit and the domain III is bound to eukaryotic initiation factor 3 (eIF3) for translation initiation. Here, we have characterized the tertiary interaction between an L-/K- rich peptide and the HCV IRES domain IV. To probe the peptide binding interface in RNA, we synthesized $^{13}C$- and $^{15}N$-double labeled RNA and the binding site was identified by using the chemical shift perturbation (CSP) NMR methods. Our results showed that the peptide binds to the upper stem of the IRES domain IV, indicating that the tertiary interaction between the IRES domain IV and the peptide would disrupt the initiation of translation of HCV mRNA by blocking the start codon exposure. This study will provide an insight into the new peptide-based anti-viral drug design targeting HCV IRES RNA.

• Archives of Pharmacal Research
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• 제8권4호
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• pp.229-236
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• 1985

Oxidation of presenegenin dimethyl ester triacetate with chromium trioxide in acetic acid yielded two compounds, 11-ketone (IV) and 12-ketone (IV) derivatives. The latter was a main product. On mild alkaline hydrolysis, IV afforded 11-keto-presenegenin dimethyl ester (V), mp 232-$234^{\circ}$, $C_{32}H_{48}O_{8}$, whereas VI did 12-keto-presenegenin dimethyl ester 12, 27-hemiketal (VIII), mp 240-$242^{\circ}$, $C_{32}H_{50}O_{8}$.

• 한국양식학회지
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• 제17권2호
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• pp.139-143
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• 2004

본 연구는 국내 양어사료에서 이용되고 있는 어유의 품질을 평가하는데 있어 어떠한 분석 항목이 중요한지 확인하여 양어용 사료의 질적 개선을 위한 기초자료를 마련하는데 그 목적이 있다. 실제 양어사료에 이용되고 있는 E사 어유를 6$0^{\circ}C$ 건조기에서 10일 동안 인위적으로 산화시켜 POV, AnV, Totox, AV, IV, 불포화지방산의 변화를 관찰하였다. 실험결과 POV, AnV, Totox의 수치는 지질의 산화가 최대 값을 나타낸 뒤 불일정하게 나타났다. 반면에, DHA와 EPA를 비롯한 PUFA는 지속적으로 감소하고, 이에 따라 SFA와 monoene은 지속적으로 증가하는 경향이 나타났다. 그리고 PUFA/SFA와 DHA/C16:0은 산화가 진행됨에 따라 지속적으로 감소하는 경향이 나타났다. 따라서, 실험결과를 통하여 POV, AnV, totox, AV, IV, 불포화지방산 등 각각의 분석항목을 단독으로 이용하여 어유 전차의 품질을 판단하기 어렵다고 판단되며, POV, AnV totok, AV, IV 불포화지방산 외에 PUFA/SFA와 DHA/C16:0의 비율도 어유의 품질평가를 하기 위한 새로운 지표가 될 것으로 사료된다.