• Korean Journal of Acupuncture
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• 제35권2호
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• pp.105-115
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• 2018

Objectives : This research aimed to verify the validities of contraindicated acupoints in acupuncture treatment in Zhenjiudacheng. Methods : We investigated contraindicated acupoints when performing needling in Zhenjiudacheng, then verified them in today's medical knowledge and clinical studies. Results : In Zhenjiudacheng, 39 acupoints - LU2, LI4, LI13, LI14, LI16, ST1, ST9, ST12, ST17, ST25, ST30, ST42, SP6, SP11, SI18, BL8, BL9, BL56, KI11, TE7, TE8, TE19, TE20, GB3, GB18, GB21, GV10, GV11, GV17, GV22, GV24, CV1, CV4, CV5, CV8, CV9, CV15, CV17 and EX-HN11 - were described to need a careful approach in acupuncture treatment and 21 acupoints among them had contraindications. Most of the contraindications can be explained based on anatomical knowledge and results of clinical studies, and acupuncture treatment at the 39 contraindicated acupoints can induce injury of tissues or organs near the acupoints. Conclusions : The contraindicated acupoints in acupuncture treatment in Zhenjiudacheng seem to have been classified based on the adverse events experienced by doctors at that time. Therefore careful acupuncture treatment at these acupoints is needed to avoid injury to tissue or organs.

• 한국임상수의학회지
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• 제22권3호
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• pp.202-205
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• 2005

본 연구는 개에서 위수혈(BL-21) 및 중완혈(CV-12)에 대한 지침의 구토억제효과를 규명할 목적으로 수행하였다. 사용 혈위는 BL-21 및 CV-12이었다. 각 군에서 구토 유발을 위하여 $2{\%}$ xylazine(2.2 mg/kg)을 투여하였으며, metoclopramide 수침은 1 mg/kg의 비율로 해당 혈위에 각각 수침하였다 대조군 및 실험군에 있어서 xylazine 투여 20분전에 BL-21 및 CV-12에 자침, metoclopramide 수침 및 뜸 처치를 각각 실시하였다. 대조군 및 실험군에서 구토율 및 구토발현시간을 각각 조사한 결과는 다음과 같았다. BL-21자침군, CV-12 자침군 및 BL-21과 CV-12 병용 자침군의 구토율은 각각 $33.3{\%}\;50.0{\%}$ 및 $33.3{\%}$로서 대조군($66.7{\%}$)보다 낮았다. BL-21 자침군, CV-12 자침군 및 BL-21과 CV-12 병용 자침군에 있어서 구토 발현 시간은 대조군과 유사하였다. BL-21 수침군 및 CV-12 수침군의 구토 억제율은 각각 $100{\%}$ 및 $83.6{\%}$로서 수침군의 대조군($63.6{\%}$)보다 높았다. 구토발현시간은 수침군의 BL-21 수침군은 0분이었으며, CV-12 수침군은 5분으로서 수침군의 대조군과 유사하였다. BL-21 뜸 처치군 및 CV-12뜸 처치군의 구토율은 각각 $33.3{\%}$로서 뜸 처치군의 대조군($66.7{\%}$)보다 낮았다. 구토발현시간은 뜸 처치군의 대조군 $2{\~}4$분, BL-21 뜸 처치군이 $2{\~}4$분 및 CV-12 뜸 처치군이 $2{\~}3$분으로서 큰 차이를 나타내지 않았다. 이상의 결과를 종합해 볼 때, 개에서 $2{\%}$ xylazine 투여로 유발된 구토에 대한 BL-21 및 CV-12의 자침, metoclopramide 수침 및 뜸 처치가 각각 구토 억제에 효과적이었으며, 또한 이들 중 BL-21에 대한 metoclopramide 수침의 구토억제 효과가 가장 우수하였다.

• Korean Journal of Acupuncture
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• 제27권2호
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• pp.35-47
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• 2010

Objectives : Chim-Gu-Kyung-Heom-Bang(CGKHB; 鍼灸經驗方) is the needle and moxa specialized document written by the doctor specialized in needle and moxa treatment of Joseon(朝鮮), Heo Im(1570-1647). The document was published in April 1644(22nd year of King Injo). CGKHB contains the needle and moxa treatment techniques accumulated by the Joseon Dynasty as well as the personal experience of Heo Im. The aim of this study is to restore the past treatment method as a method of Needle Insertion Method at CV12(NIM-CV12, needle to penetrate blood vessel technique) in CGKHB.. Methods : Through Dong-Yi-Bao-Gam(DYBG; 東醫寶鑑), the implication of Korean medicine study of the Jungwan(CV12) has been studied. Next is the contemplation of the NIM-CV12 of CGKHB with the Acupuncture Treatment Using Jungwan(中脘鍼法) of Park Tae-won and Acupuncture Treatment for Byeokjeok(癖積鍼法) of "Geup Yubang". Results and Conclusions : 1. CV12 is one of the acupuncture points representing stomach(脾胃), middle energizer(中焦), phlegm-fluid retention(痰飮) and greater yin(太陰). 2. NIM-CV12 of CGKHB is the technique to penetrate the needle into the CV12 strictly relying on tactile sense of a person who give the penetration. This CV12 administration was carried out at intervals of every 7 or 8 day. During the administration period, the patient was not allowed to intake excessive amount of food. 3. The Acupuncture Treatment Using Jungwan(中脘鍼法) of Park Tae-won and Acupuncture Treatment for Byeokjeok(癖積鍼法) of "GeupYubang", existed in the same era of the NIM-CV12 of CGKHB, have similar linkage to the NIM-CV12 of Heo Im.

• Journal of Microbiology and Biotechnology
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• 제27권4호
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• pp.834-837
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• 2017

A distinct double-stranded RNA (dsRNA) cryptic virus, named spinach cryptic virus 1 (SpCV1), was identified from spinach transcriptome datasets. The SpCV1 genome has two dsRNA genome segments. The larger dsRNA1 has an open reading frame for a conserved RNA-dependent RNA polymerase (RdRp). The smaller dsRNA2 encodes a putative coat protein (CP). The sequence identity of SpCV1 RdRp and CP to the closest cryptic virus is 81% and 60%, respectively. Phylogenetic analysis indicates that SpCV1 is a novel member of the genus Alphapartitivirus (family Partitiviridae).

• Biomolecules & Therapeutics
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• 제7권1호
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• pp.44-53
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• 1999

The resistant strains due to the extended-spectrum $\beta$-lactamase (ESBL) were susceptible to cefatrizine combined with clavulanic acid. The purpose of this study was to evaluate the in vitro and in vivo antibacterial activities of cefatrizine/clavulanic acid (CTRZ/CV) combination at a ratio of 2 : 1 in comparison with cefaclor (CCLO), cefuroxime (CRXM), cefuroxime axetil (CRXMA) and amoxicillin/clavulanic acid (AMXCCV). CTRZ/CV showed good activity against laboratory strains of gram-positive and gram-negative bacteria and exhibited excellent antibacterial activity against $\beta$-lactamase-producing strains. The bactericidal activity of CTRZ/CV was superior to that of CCLO and CRXM, and almost equal to that of AMXCCV against the $\beta$-lactamase-producing strains. The in vitro results were substantiated. by in vivo mouse experimental infection studies with $\beta$-lactamase-producing and non-producing strains. In mixed experimental infection due to $\beta$-lactamase-producing and non-producing strains, the therapeutic efficacy of CTRZ/CV was superior to that of CTRZ, CCLO, CRXMA and AMXCCV. In respiratory tract infection in mice due to Klebsiella pneumoniae EB4O, CTRZ/CV was more erective than CCLO, CRXMA and AMXCCV and also more efficacious than CCLO, CRXMA and AMXCCV in urinary tract infection in mice due to Escherichia coli EB13. These results indicate that CTRZ/CV is a useful drug for the treatment of infection caused by $\beta$-1actamase-producing strains including ESBL-producing strains.

• 대한수의학회지
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• 제33권4호
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• pp.735-746
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• 1993

Electrocardiographic parameters of amplitude and the shape of waves on the unipolar precordial chest leads in the normal Korean native cattles have been measured with a 3 channel electrocardiograph built in a computed and analysis. The study was conducted on 98 heads of mean age of 17.6 months. The wave forms of P, T and QRS complex wave in all leads showed various types. The parameters of the amplitude in the wave types showed the most frequency in each lead that were analyzed as follow : 1. In P wave, amplitudes of positive type showed a frequency of 92.9% and 93.9% in leads $CV_6LU$ and $CV_6LL$ that were $83.8{\pm}31.0{\mu}V$ and $76.0{\pm}30.7{\mu}V$, and negative type showed a frequency of 97.9% in lead V 10 that were $-80.2{\pm}29.4{\mu}V$, respectively. But the plate type in leads $CV_6RU$ and $CV_6RL$ showed frequency of 48% and 58.3%, respectively. 2. Average amplitude of the QRS complex were in a range of $277.0{\pm}154.0{\mu}V$ to $648.2{\pm}146.2{\mu}V$(mean of $418.8{\pm}139.4{\mu}V$) in all leads that were manifested the Low-Voltage QRS complex(below 1 mV in unipolar precordial leads). Average amplitudes of each wave type in the QRS complex were $-250.0{\pm}139.8{\mu}V$ and $-399.2{\pm}226.8{\mu}V$ in the QS group types that showed a frequency of 50.0% and 82.5% in the leads $CV_6LU$ and $CV_6LL$, respectively. And average amplitudes of the R group types showed a frequency of 85.6%, 56.1% and 75.8% in the $CV_6RU$, $CV_6RL$ and $V_{10}$ that were $321.5{\pm}142.1{\mu}V$, $271.6{\pm}139.9{\mu}V$ and $552.4{\pm}132.7{\mu}V$, respectively. 3. In T waves, Amplitudes of the positive type showed a frequency of 60.2%, 46.9% and 83.7% in leads of $CV_6LL$, $CV_6RU$ and $CV_6RL$ that were respectively $184.7{\pm}93.7{\mu}V$ $103.7{\pm}64.43{\mu}V$ and $111.8{\pm}39.3{\mu}V$, the negative type showed a frequency of 62.2% and 93.7% in leads $CV_6LU$ and $V_{10}$ that were $142.2{\pm}82.1{\mu}V$ and $-280.3{\pm}107.2{\mu}V$, respectively. 4. Average amplitude of ST segment were $3.7{\pm}33.1{\mu}V$, $0.9{\pm}23.1{\mu}V$, $10.9{\pm}28.6{\mu}V$, $5.8{\pm}28.3{\mu}V$ and $-34.7{\pm}48.4{\mu}V$ in leads $CV_6LL$, $CV_6RU$, $CV_6RL$, $CV_6LU$ and $V_{10}$ respectively.

• 공업화학
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• 제23권5호
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• pp.445-449
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• 2012

고분자 전해질막 연료전지의 대량 생산을 위하여 막-전극 접합체(MEA) 활성화 방법의 개발이 중요한 현안이다. 현재 개발된 MEA활성화 방법은 시간이 많이 소요됨으로 인해 수소의 사용량 또한 증가하여 연료전지의 상용화에 큰 걸림돌이 되고 있다. 통상적인 활성화 방법은 활성화 원리를 주로 전해질 수화 관점에서 이해하였다. 반면, 본 논문에서 제안된 순환전압전류(cyclic voltammetry, CV) 활성화 방법은 전해질 및 촉매적 관점에서 별도로 분리하여 이해하였다. 따라서 전해질 관점에서는 상대 습도 100%인 가습된 질소를 공급하여 전극 및 막의 전해질을 수화시키는 과정으로 구성되고, 촉매적 관점에서는 CV 사이클을 수행하여 백금 촉매에 흡착되어 있는 불필요한 오염물질, 또는 산화피막을 제거하는 과정으로 수행된다. CV 활성화법은 2.5 h 내에 활성화가 종료되어 활성화 시간을 크게 단축시킬 수 있을 뿐만 아니라, 수소 사용량도 기존 활성화 방법에 비하여 1/4 이하로 감소시킬 수 있어서 효과적인 연료전지 활성화 방법으로 제안하고자 한다.

• 산업경영시스템학회지
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• 제39권1호
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• pp.116-122
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• 2016

Recently, the production cycle in manufacturing process has been getting shorter and different types of product have been produced in the same process line. In this case, the control chart using coefficient of variation would be applicable to the process. The theory that random variables are located in the three times distance of the deviation from mean value is applicable to the control chart that monitor the process in the manufacturing line, when the data of process are changed by the type of normal distribution. It is possible to apply to the control chart of coefficient of variation too. ${\bar{x}}$, s estimates that taken in the coefficient of variation have just used all of the data, but the upper control limit, center line and lower control limit have been settled by the effect of abnormal values, so this control chart could be in trouble of detection ability of the assignable value. The purpose of this study was to present the robust control chart than coefficient of variation control chart in the normal process. To perform this research, the location parameter, ${\bar{x_{\alpha}}}$, $s_{\alpha}$ were used. The robust control chart was named Tim-CV control chart. The result of simulation were summarized as follows; First, P values, the probability to get away from control limit, in Trim-CV control chart were larger than CV control chart in the normal process. Second, ARL values, average run length, in Trim-CV control chart were smaller than CV control chart in the normal process. Particularly, the difference of performance of two control charts was so sure when the change of the process was getting to bigger. Therefore, the Trim-CV control chart proposed in this paper would be more efficient tool than CV control chart in small quantity batch production.

• 한국가정과학회지
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• 제7권3호
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• pp.49-58
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• 2004

The purpose of the study was to verify if or not as funtional food by estimating antitumor activity and antimicrobial activity of Coriolus versicolor(Fr.)Quel and Ganoderma Lucidum (Fr.)Karst. 1. The contents of moisture. crude fiber and crude protein of GL were higher $(18.28\%,\;10.3\%,\;78.4\%)$ than that of CV, but the content of crude lipid GL was higher than that of CV. 2. Inhibitory effects of on the growth of AGS human gastric adenocarcinoma cells and HT-29 human colon adenocarcinoma cell were increased by increasing of concentration in added methanol extracts of CV and GL. 3. Antimicrobial activity on Escherichia col1; Staphylococcus aureus, Salmonella typhimurium existed methanol extracts of CV. Therefore. it is suggested that CV is worth as functional food.

• 대한의료기공학회지
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• 제14권1호
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• pp.52-62
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• 2014

Objective : The aim of this study is to analyze the effectiveness of Korean Medicine treatment on post-hysterectomy syndrome patients by thermographic change during treatment. Methods : 5 female patients who had a hysterectomy within a year were treated with Korean Medicine concluding acupuncture, herbal medicine, cupping therapy, herbal bath. We evaluated the thermographic differences by checking Digital Infrared Thermal Imaging(D.I.T.I.) at CV17(膻中), CV4(關元), ST3(巨髎), BL15(心兪), and BL23(腎兪). Results : In consequence of Korean Medicine Treatment for 3 weeks, thermographic differences between CV17(膻中) and CV4(關元), ST3(巨髎) and CV4(關元), BL15(心兪), and BL23(腎兪) tended to decrease. Conclusion : After Korean Medicine treatment, thermographic differences between upper body and lower body tended to decrease cause shangrexiahanzheng(上熱下寒證) made by hysterectomy became moderated.