• Journal of Dental Rehabilitation and Applied Science
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• v.25 no.2
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• pp.171-181
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• 2009

The objective of this study was to analyse stress distribution of maxillary complex by use of face mask. The construction of the three-dimensional FEM model was based on the computed tomography(CT) scans of 13.5 years-old male subject. The CT image were digitized and converted to the finite element model by using the mimics program, with PATRAN. An anteriorly directed force of 500g was applied at the first premolar 45 degrees downwards to the FH plane and at the first molar 20 degrees downwards to the FH plane. When 45 degrees force was applied at maxillary first premolar, there were observed expansion at molar part and constriction at premolar part. The largest displacement was 0.00011mm in the x-axis. In the y-axis, anterior displacement observed generally 0.00030mm at maximum. In the z-axis, maxillary complex was displaced 0.00036 mm forward and downward. When 20 degrees force was applied at maxilla first molar, there were observed expansion at lateral nasal wall and constriction at molar part. The largest displacement was 0.001mm in the X-axis. In the Y-axis, anterior displacement observed generally 0.004mm at maximum. In the Z-axis, ANS was displaced upward and pterygoid complex was displaced downward. The largest displacement was 0.002mm.

• Archives of Reconstructive Microsurgery
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• v.8 no.1
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• pp.71-76
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• 1999

Until recently, the cranial base tumors were deemed unresectable due to the inability to diagnose the extent of the involvement accurately and to approach and excise the tumor safely. With refinements in CT and NMR scanning and development of craniofacial techniques, reconstruction becomes absolutely crucial in allowing successful resection of these tumors. Resection of these tumors may sometimes result in massive and complex extirpation defects that are not amendable to local tissue closure. In such cases, the free tissue transfer was a useful alternative because it can provide large amount of well-vascularized tissues and reliable separation of intracranial space from bacterial flora of the upper airway. The microvascular free tissue transfer was used in 9 patients at our center to reconstruct the cranial base defects. Of these, 8 were free rectus muscle flaps, and 1 was free latissimua dorsi muscle flap. There were 1 case of partial flap loss and 1 case of postoperative wound infection. The large, complex defects were successfully reconstructed by one stage operation and the functional and aesthetic results were satisfactory with acceptable complication rates.

• Journal of Dental Rehabilitation and Applied Science
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• v.23 no.4
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• pp.359-371
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• 2007

Recently, many studies were reported accurate analysis of facemask effect due to the development of the personal computers and computer programs. The aim of this study is appropriate protraction direction of facemask using finite element study with computer aided design and computer aided measurement. The construction of the three dimensional FEM was based on the computer tomography(CT) scans of 13.5 year-old male subject. Protraction force of 500 mg was applied at 0, 30, 60 and 90 degrees downwards to the Frankfort horizontal plane, and maxillary displacement and stress distribution were measured. When 60 degree force was applied, it showed forward movement of premolar roots area and downward movement of anterior nasomaxillary area, and others showed clockwise rotation movement of the nasomaxillary complex. Finally, we can produce the protraction of maxillary bone without rotation of maxilla about 60 degrees.

• Macromolecular Research
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• v.17 no.7
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• pp.538-543
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• 2009

In this study, methotrexate (MTX)-encapsulated polymeric micelles using methoxy poly(ethylene glycol) (MPEG)-grafted chitosan (ChitoPEG) copolymer were prepared. The MIX-incorporated polymeric micelles of ChitoPEG copolymer has a particle size of around 50-100 nm. In 1H nuclear magnetic resonance (NMR) study, the specific peaks of MTX disappeared in heavy water ($D_2O$) and only the specific peak of MPEG was observed, while all of the peaks were confirmed in dimethyl sulfoxide (DMSO). These results indicated that MTX was complexed with chitosan and then formed an ion complex inner-core of the polymeric micelle in an aqueous environment. The drug contents of the polymeric micelle were around $4{\sim}12%$ and the loading efficiency of MTX in the polymeric micelles was higher than 60% (w/w) for all of the formulations. The cytotoxicity of MIX and MTX-incorporated polymeric micelle against CT26 tumor cells was not significantly changed.

• YAKHAK HOEJI
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• v.33 no.3
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• pp.141-148
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• 1989

The weak UV absorbing antihistaminics such as chlorpheniramine, triprolidine, tripelennamine and diphenhydramine were analyzed by charge-transfer spectrophotometric method. The results obtained are summarized as folows. It was possible to determine a weak UV absorbing antihistaminics using the intense charge-transfer UV bands in chloroform. Charge transfer complexes were formed in a 1:1 ratio between antihistaminics and iodine in chloroform. Linear relationship was found between absorbance and concentration in the range of $1.0\;{\times}\;10^{-5}M-5.0\;{\times}\;10^{-5}M$ for chlorpheniramine( ${\varepsilon}\;=\;2.082\;{\times}\;10^4$) and tripelennamine ( ${\varepsilon}\;=\;1.578\;{\times}\;10^4$), $1.0\;{\times}\;10^{-5}M-8.0\;{\times}\;10^{-5}M$ for triprolidine ( ${\varepsilon}\;=\;1.120\;{\times}\;10^4$) and $1.0\;{\times}\;10^{-5}M-1.0\;{\times}\;10^{-4}M$ for diphenhydramine ( ${\varepsilon}\;=\;9.900\;{\times}\;10^3$). Charge transfer complexes of chlorpheniramine, triprolidine and tripelennamine have absorption maxima at 293 nm and complex form of diphenhydramine has absorption maximum at 270 nm. By UV, IR spectra, it could be inferred that CT-complexes were formed by interaction between the basic nitrogen of antihistaminics as electron donor (non bonding electron) and iodine as electron acceptor (${\sigma}$ bonding electron).

• Fibers and Polymers
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• v.1 no.2
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• pp.97-102
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• 2000

Pitch precursors were synthesized from coal tar(CT) and pyrolysis fuel oil(PFO, petroleum residue oil) at relatively low temperature of $250^{\circ}$, in the presence of horontrifluorideidiethyletherate complex(BFDE) as a catalyst and nitrobenzene(NB) as a co-catalyst. The softening point, nitrogen content and carbon yield increased with an increase of concentration of NB. The pitch precursors with good spinnability were prepared by removing the volatile components through $N_2$ blowing. The precursor pitches were spun through a circular nozzle, stabilized at $310^{\circ}$ and finally carbonized at $1000^{\circ}$. The optically anisotropic structure formed at the absence of NB was changed into isotropic structure, showing a decrease in size of the flow domain. The hollow carbon fiber could be prepared in the process of stabilization. The results proposed that the morphology of carbon materials could be controlled by changing the concentration of catalyst and/or co-catalyst and/or stabilization condition that affect on the mobility of molecules during carbonization.

• Bulletin of the Korean Chemical Society
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• v.33 no.4
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• pp.1290-1296
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• 2012

Fenton reaction and iron autoxidation have been debated for the major process in ROS mediated DNA cleavage. We compared both processes on iron oxidation, DNA cleavage, and cyclic voltammetric experiment at different pHs. Both oxidation reactions were preferred at basic pH condition, unlike DNA cleavage. This indicates that iron oxidation and the following steps probably occur separately. The ROS generated from autoxidation seems to be superoxide radical since sod exerted the best inhibition on DNA cleavage when $H_2O_2$ was absent. In comparison of cyclic voltammograms of $Fe^{2+}$ in NaCl solution and phosphate buffer, DNA addition to phosphate buffer induced significant change in the redox cycle of iron, indicating that iron may bind DNA as a complex with phosphate. Different pulse voltammogram in the presence of ctDNA suggest that iron ions are recyclable at acidic pH, whereas they may form an electrically stable complex with DNA at high pH condition.

• Journal of the Korean Society of Radiology
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• v.9 no.6
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• pp.337-342
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• 2015

The one-year-follow-up test of abdomen/pelvis from 10 patients who were scanned more than twice a years were analyzed the radiation dose and image quality depend on the position of the arm retrospectively from January to December in 2013. There were classified two groups, group A was examined with raising an arm on standard position and group B was performed with lowering an arm, respectively. Group A of an average mAs from the first dose amount was shown 11.4% less compared to Group B. And the value of CTDI from Group B also was investigated 11.3% less. To compare the quality comparison of the second image as histogram value, the value of max from both of two groups was measured similarly. However, a big difference was shown from the value of min and SD, the short dose was appeared depends on the position of arm even though Group A was radiated more than Group B. Less exposure to the medical image quality only by working CT scan when the examiner actively raise the arm before the development and testing of high-end equipment introduction of complex algorithms for obtaining an optimized image will be provided to the patient.

• The Journal of Engineering Geology
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• v.21 no.4
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• pp.381-391
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• 2011

Weathering can reduce rock strength and eventually affect the structural stability of a rock mass, which is important in the field of engineering geology. Several methods have been developed to evaluate the degree of weathering, including the chemical weathering index. In this study, we analyzed the weathering degree and characteristics of microtextures and pores in crystalline rocks (gneiss and granites) based on petrographic observations, the chemical weathering index, mineralogy by XRD, microtextural analysis by SEM/EDS, measurements of pore size and surface area by the BET method, and microporosity by X-ray CT. The formation of secondary minerals and microtexture in gneiss and granitic rocks are assumed to be affected by complex processes such as dissolution, precipitation, and fracturing. Hence, it is clear that some chemical weathering indices that are based solely on whole-rock chemistry (e.g., CIA and CWI) are unable to provide reliable assessments of the degree of weathering. Great care is needed to evaluate the degree of chemical weathering, including an understanding of the mineralogy and microtexture of the rock mass, as well as the characteristics of micropores.

• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.2
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• pp.163-173
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• 2013

When the mandible performs opening movement, the condyle-disk complex conducts sliding movement along the articular eminence. Thus, anatomic configuration of articular eminence is very important to normal movement of TMJ. The purpose of this study was to measure the posterior slope of the articular eminence and evaluate the effect of a pathologic bone change in the condylar head on the stiffness of articular eminence, and compare the differences of the articular eminence slope by gender and age using dental cone-beam CT. As using i-CAT Cone-Beam Computed Tomography, the CT images of 204 TMJs of 102 patients(43 men and 59 women, mean age: 37.7 years) who were diagnosed at Wonkwang University Sanbon Dental Hospital were evaluated. All images were converted into a TMJ analysis mode to observe the continuous sagittal section images and coronal section images of the joints. To observe and assess bone changes in the condyle, three dentists measured the stiffness of the articular eminence on the same images, and when two of the three dentists agreed on their reading, these results were adopted and recorded. The articular eminence slope, considering the condylar anatomic configuration, was measured in three regions, namely, lateral part, central part, and medial part of the condyle. In the cases of a normal condyle(NCBC) and a condyle(CBC) with bone change, the articular eminence slopes were $57.0^{\circ}$(NCBC) and $51.8^{\circ}$(CBC) at the medial part, $57.9^{\circ}$(NCBC) and $52.4^{\circ}$(CBC) at the central part, and $55.1^{\circ}$(NCBC) and $49.5^{\circ}$(CBC) at the lateral part of the condyle. And the articular eminence slope of the condyle with bone change demonstrated less steepness than that of normal condyle (p<0.05). The articular eminence slope showed mediolaterally that it was the steepest at the central, followed by at the medial, and at the lateral (p<0.05). There were no significant differences by the gender and the age (p.0.05).