• Journal of Radiation Protection and Research
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• v.40 no.1
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• pp.10-16
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• 2015

Bone changes are common sequela of irradiation in growing animal. The purpose of this study was to establish an experimental model of radiation-induced bone loss in growing mice using micro-computed tomography (${\mu}CT$). The extent of changes following 2 Gy gamma irradiation ($2Gy{\cdot}min^{-1}$) was studied at 4, 8 or 12 weeks after exposure. Mice that received 0.5, 1.0, 2.0 or 4.0 Gy of gamma-rays were examined 8 weeks after irradiation. Tibiae were analyzed using ${\mu}CT$. Serum alkaline phosphatase (ALP) and biomechanical properties were measured and the osteoclast surface was examined. A significant loss of trabecular bone in tibiae was evident 8 weeks after exposure. Measurements performed after irradiation showed a dose-related decrease in trabecular bone volume fraction (BV/TV) and bone mineral density (BMD), respectively. The best-fitting dose-response curves were linear-quadratic. Taking the controls into accounts, the lines of best fit were as follows: BV/TV (%) = $0.9584D^2-6.0168D+20.377$ ($r^2$ = 0.946, D = dose in Gy) and BMD ($mg{\cdot}cm^{-3}$) = $8.8115D^2-56.197D+194.41$ ($r^2$ = 0.999, D = dose in Gy). Body weight did not differ among the groups. No dose-dependent differences were apparent among the groups with regard to mechanical and anatomical properties of tibia, serum ALP and osteoclast activity. The findings provide the basis required for better understanding of the results that will be obtained in any further studies of radiation-induced bone responses.

• Korean Journal of Computational Design and Engineering
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• v.9 no.2
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• pp.122-132
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• 2004

Progressive mesh representation and generation have become one of the most important issues in network-based computer graphics. However, current researches are mostly focused on triangular mesh models. On the other hand, solid models are widely used in industry and are applied to advanced applications such as product design and virtual assembly. Moreover, as the demand to share and transmit these solid models over the network is emerging, the generation and the transmission of progressive solid models depending on specific engineering needs and purpose are essential. In this paper, we present a Cellular Topology-based approach to generating and transmitting progressive solid models from a feature-based solid model for internet-based design and collaboration. The proposed approach introduces a new scheme for storing and transmitting solid models over the network. The Cellular Topology (CT) approach makes it possible to effectively generate progressive solid models and to efficiently transmit the models over the network with compact model size. Thus, an arbitrary solid model SM designed by a set of design features is stored as a much coarser solid model SM/sup 0/ together with a sequence of n detail records that indicate how to incrementally refine SM/sup 0/ exactly back into the original solid model SM = SM/sup 0/.

• Korean Journal of Computational Design and Engineering
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• v.16 no.6
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• pp.458-466
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• 2011

The morphology of a bone is closely associated with its biomechanical response. Thus, much research has been focused on analyzing the effects of variation of bone morphology with subject-specific models. Subject-specific models, which are generally achieved from 3D imaging devices like CT and MRI, incorporate more of the detailed information that makes a model unique. Hence, it may predict individual responses more accurately. Despite these powerful characteristics, specific models are not easily parameterized to the extent possible with statistical models because of their morphologic complexities. Thus, it is still proven challenging to analyze morphologic variations of subject-specific models across changes due to aging or disease. The aim of this article is to propose a generic and robust parametric morphing method for a subject-specific bone structure. We demonstrate this by using the proposed method on a model of a human proximal femur. Automatic segmentation algorithms are also presented to parameterize the specific model efficiently. A total of 48 femur models were evaluated for defining morphing vector fields. Also, several anatomical and mechanical functions of femur were considered as morphing constraints, and the NURBS interpolating technique was applied in the method to guarantee the generality of our morphed results.

• The Transactions of the Korean Institute of Power Electronics
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• v.4 no.5
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• pp.455-461
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• 1999

In this paper, we present the 3DOF force-rei1ecting interface which allows to acquire force of objc'Ct within a a virtual environment. This system is comlxlsed of device, virtual environment model, and force-rei1ecting r rendering algorithm. We design a J DOF force reflecting device using the pc$\alpha$allel linkage, torque shared by W wire, and the controller of system applied by impedance control algorithm. The force reflecting behaviour i implemented as a function position is equivalent to controlling the mechanical impedance felt by the user. E Especially how force should be supplied to user, we know using a God-Object algorithm As we experiment a system implement$\varepsilon$d by the interface of 3D virtual object and 3DOF force reJll'Cting i interface, we can feel a contact, non contact of :)D virtual object surface and sensin앙 of push button model.utton model.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.907-910
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• 2005

Although several artificial disc designs have been developed for the treatment of discogenic low back pain, biomechanical change with its implantation was rarely studied. To evaluate the effect of artificial disc implantation on the biomechanics of functional spinal unit, nonlinear three-dimensional finite element model of L4-L5 was developed with 1-mm CT scan data. Two models implanted with artificial discs, SB $Charit\acute{e}$ or Prodisc, via anterior approach were also developed. The implanted model predictions were compared with that of intact model. Angular motion of vertebral body, force on spinal ligaments and facet joint, and the stress distribution of vertebral endplate for flexion-extension, lateral bending, and axial rotation with a compressive preload of 400 N were compared. The implanted model showed increased flexion-extension range of motion and increased force in the vertically oriented ligaments, such as ligamentum flavum, supraspinous ligament and interspinous ligament. The increase of facet contact force on extension were greater in implanted models. The incresed stress distribution on vertebral endplate for implanted cases indicated that additinal bone growth around vertebral body and this is matched well with clinical observation. With axial rotation moment, relatively less axial rotation were observed in SB $Charit\acute{e}$ model than in ProDisc model.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.20 no.7
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• pp.2257-2265
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• 1996

In the cold rolling mill, it is very important that a constrained static flow stress of rolled strip and rolling force calculation model be exactly considered to improve an prediction accuracy for rolling forces. Therefore, in this study, the values of the constrained static flow stress are used by deriving the regression equation which is a function of rolling conditions(FDT, CT) and chemical compositions(C, Si, Mn), previously applied by making the tables of yield strength for hot coils with size. And with the consideration that an elastic deformation part of an rolled strip appears at the entry and delivery side of the contacting area between the work roll and rolled strip is calculated. By applying these methods, the more accurate prediction for rolling force is obtained. As a results, the deviation of thickness is significantly reduced in the rolling direction.

• Journal of Institute of Control, Robotics and Systems
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• v.17 no.8
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• pp.807-813
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• 2011

High precision of planning in the preoperative phase can contribute to increase operational safety during computer-aided spinal fusion surgery, which requires extreme caution on the part of the surgeon, due to the complexity and delicacy of the procedure. In this paper, an advanced preoperative planning framework for spinal fusion is presented. The framework is based on spinal pedicle data obtained from CT (Computed Tomography) images, and provides optimal insertion trajectories and pedicle screw sizes. The proposed approach begins with safety margin estimation for each potential insertion trajectory that passes through the pedicle volume, followed by procedures to collect a set of insertion trajectories that satisfy operation safety objectives. The radius of a pedicle screw was chosen as 70% of the pedicle radius. This framework has been tested on 68 spinal pedicles of 8 patients requiring spinal fusion. It was successfully applied, resulting in an average success rate of 100% and a final safety margin of $2.44{\pm}0.51mm$.

• Journal of Power System Engineering
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• v.15 no.6
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• pp.73-80
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• 2011

The experimental investigation focuses on an influence of artificial aging time in longitudinal butt welded Al 6013-T4 aluminum alloy on the fatigue crack growth resistance. The preferred welding processes for this alloy are frequently tungsten inert gas welding (TIG) process due to its comparatively easier applicability and better weldability than other gas metal arc welding. Fatigue crack growth tests were carried out on compact tension specimens (CT) in longitudinal butt TIG welded after T82 heat treatment was varied in three artificial aging times of 6 hours, 18 hours and 24 hours. Of the three artificial aging times, 24 hours of artificial aging time are offering better resistance against the growing fatigue cracks. The superior fatigue crack growth resistance preferred spatial variation of materials within each specimen in the Paris equation based on reliability theory and fatigue crack growth rate by crack length are found to be the reasons for superior fatigue resistance of 24 hours of artificial aging time was compared to other joints. The highest of crack propagation resistance occurs in artificial aging times of 24 hours due to the increase in grain size (fine grained microstructures).

• Transactions of the Korean Society of Mechanical Engineers A
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• v.31 no.1 s.256
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• pp.70-76
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• 2007

Elastic-plastic fracture mechanics is popularly used for integrity evaluation of major components, however, it is not easy to extract standard specimens from operating facility. This paper examines how ductile fracture toughness is characterized by a small punch testing technique in conjunction with finite element analyses incorporating a damage model. At first, micro-mechanical parameters constituting Rousselier model are calibrated for typical nuclear materials using both estimated and experimental load-displacement (P-$\delta$) curves of miniaturized specimens. Then, fracture resistance (J-R) curves of relatively larger standard CT specimens are predicted by finite element analyses employing the calibrated parameters and compared with corresponding experimental ones. It was proven that estimated results by the proposed method using small punch specimen is promising and might be used as a useful tool for ductile crack growth evaluation.

• Journal of the Korean Society for Precision Engineering
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• v.23 no.4 s.181
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• pp.116-123
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• 2006

During the last two decades, many researchers investigated influences of stress triaxiality on ductile fracture for various specimens and structures. With respect to a transferability issue, the local approach reflecting micro-mechanical specifics is one of effective methods to predict constraint effects. In this paper, the applicability of the local approach was examined through a series of finite element analyses incorporating modified GTN (Gurson-Tvergaard-Needleman) and Rousselier models as well as fracture toughness tests. To achieve this goal, fracture resistance (J-R) curves of several types of compact tension (CT) specimens with various crack length, with various thickness and with/without 20% side- grooves were estimated. Then. the constraint effects were examined by comparing the numerically estimated J-R curves with experimentally determined ones. The assessment results showed that the damage models might be used as useful tool for fracture toughness estimation and both the crack length and thickness effects should be considered for realistic structural integrity evaluation.